Search clinical trials for: Chloroquine/Primaquine

Total 269 results

Menzies School of Health Research
Tribhuvan University, Nepal

Active, not recruiting

Short Course Radical Cure of P. Vivax Malaria in Nepal

Malaria | Malaria, Vivax | Malaria,Falciparum

Nepal
PATH
Mahidol Oxford Tropical Medicine Research Unit

Terminated

Assessing a Risk Model for G6PD Deficiency

Malaria, Vivax | G6PD Deficiency

Thailand
GlaxoSmithKline
Medicines for Malaria Venture

Completed

Ph 2B/3 Tafenoquine (TFQ) Study in Prevention of Vivax Relapse

Malaria, Vivax

Thailand, India, Brazil, Ethiopia, Peru, Bangladesh, Cambodia, Philippines
Ministry of Health, Bhutan
Menzies School of Health Research; Asia Pacific Malaria Elimination Network

Unknown

Parasitic Clearance and Recurrence Rates Among Patients With Vivax Malaria (BCAPES)

Parasitemia

Bhutan
Menzies School of Health Research
Ministry of Health, Malaysia

Unknown

Artemether-lumefantrine vs Chloroquine for Uncomplicated P. Vivax Malaria in Malaysia (PRIMAL)

Plasmodium Vivax Malaria Without Complication

Malaysia
University of Oxford
Mahidol University; National Malaria and Leishmaniasis Control Program, Afghanistan

Completed

Estimating the Risk of Plasmodium Vivax Relapses in Afghanistan (VRA)

Vivax Malaria

Afghanistan
University of Oxford
Mahidol Oxford Tropical Medicine Research Unit; Nangarhar University

Completed

G6PD Assessment Before Primaquine for Radical Treatment of Vivax Malaria (GAP)

Vivax Malaria

Afghanistan
LILIA GONZALEZ CERON
Pan American Health Organization; Instituto de Diagnóstico y Referencia Epidemiológicos... and other collaborators

Completed

Effectiveness of Malaria Treatment in Mexico (EMTM)

Malaria
University of Mississippi, Oxford
University of Colorado, Denver; Southern Research Institute

Unknown

Primaquine Enantiomers in G6PD Deficient Human Volunteers

G6PD Deficiency

United States
U.S. Army Medical Research and Development Command
GlaxoSmithKline

Terminated

Study to Evaluate the Efficacy and Safety of Tafenoquine for the Treatment of Plasmodium Vivax in Adults

Malaria | Plasmodium Vivax

Thailand
London School of Hygiene and Tropical Medicine
World Health Organization; United Nations High Commissioner for Refugees; HealthNet... and other collaborators

Completed

ACT With Chloroquine, Amodiaquine & Sulphadoxine-pyrimethamine in Pakistan

Malaria | Vivax Malaria | Falciparum Malaria

Pakistan
University of Oxford
Mahidol University

Completed

Study on the Treatment of Vivax Malaria (VHX)

Vivax Malaria

Thailand
GlaxoSmithKline
Medicines for Malaria Venture

Completed

Study to Assess the Incidence of Hemolysis, Safety, and Efficacy of Tafenoquine (SB-252263, WR238605) Versus Primaquine in Subjects With Plasmodium Vivax Malaria

Malaria, Vivax

Thailand, Vietnam, Colombia, Brazil, Ethiopia, Peru
Dinka Dugassa
Ethiopian Public Health Institute

Completed

Therapeutic Efficacy of Chloroquine Plus Primaquine in the Treatment of Uncomplicated Plasmodium Vivax (CQ+PQ)

Malaria | Efficacy | Vivax Malaria | Chloroquine

Ethiopia
Centers for Disease Control and Prevention

Completed

Plasmodium Vivax Efficacy Trial in Cruzeiro do Sul, Acre, Brazil

Malaria

Brazil
Menzies School of Health Research
Ministry of Health, Bhutan

Completed

Safety and Efficacy of Chloroquine and Primaquine for Vivax Malaria in Bhutan

Vivax Malaria

Bhutan
Menzies School of Health Research
International Centre for Diarrhoeal Disease Research, Bangladesh

Completed

A Study to Assess Safety of Current Standard Malaria Treatment and an Assessment of G6PD Status in South-east Bangladesh

Malaria
Centre Hospitalier de Cayenne
Oswaldo Cruz Foundation

Recruiting

Radical CUREfor MAlaria Among Highly Mobile and Hard-to-reach Populations in the Guyanese Shield (CUREMA)

Malaria, Vivax

Brazil, Suriname
Research Institute for Tropical Medicine, Philippines
World Health Organization

Completed

TES of Chloroquine for Pv in the Philippines in 2016 (TES)

Malaria | Vivax Malaria | Recrudescence
University of Mississippi, Oxford

Completed

Metabolism and Pharmacokinetics of Primaquine Enantiomers in Human Volunteers, Study 1

Malaria

United States
GlaxoSmithKline
Medicines for Malaria Venture

Completed

G6PD (Glucose-6-phosphate Dehydrogenase) Study to Evaluate Hemolysis Potential of TFQ (Tafenoquine)

Malaria

Thailand
Seattle Children's Research Institute (SCRI)

Completed

Malaria Challenge in Healthy Volunteers (ITV)

Malaria

United States
Research Institute for Tropical Medicine, Philippines
World Health Organization

Completed

TES of Artemether-lumefantrine for Pf and Chloroquine for Pv in the Philippines From 2013-2014 (TES)

Malaria | Vivax Malaria | Falciparum Malaria | Malaria Recrudescence
University of Mississippi, Oxford

Completed

Metabolism and Pharmacokinetics of Primaquine Enantiomers in Human Volunteers Receiving a Seven Day Dose Regimen

Malaria | Glucose 6 Phosphate Dehydrogenase Deficiency

United States
University of California, San Francisco
Bill and Melinda Gates Foundation; Wellcome Trust; Malaria Research and Training... and other collaborators

Completed

Phase2a Primaquine Dose Escalation Study

Malaria

Mali
Fundação de Medicina Tropical Dr. Heitor Vieira...
Oswaldo Cruz Foundation; Conselho Nacional de Desenvolvimento Científico e...

Active, not recruiting

Safety and Efficacy of Different Regimens of Primaquine on Vivax Malaria Treatment in G6PD Deficient Patients

Vivax Malaria | G6PD Deficiency

Brazil
Oswaldo Cruz Foundation
University of Sao Paulo

Completed

Efficacy of Chloroquine (CQ) Alone Compared to Concomitant CQ and Primaquine for Plasmodium Vivax Infection

Malaria, Vivax

Brazil
London School of Hygiene and Tropical Medicine
HealthNet TPO

Completed

Trial of Artesunate Combination Therapy in Pakistan

Uncomplicated Falciparum Malaria

Pakistan
Centers for Disease Control and Prevention
Columbia University; United States Agency for International Development (USAID) and other collaborators

Completed

Ethiopia Antimalarial in Vivo Efficacy Study 2012

Plasmodium Vivax Infection

Ethiopia
University of California, San Francisco
Pan American Health Organization

Withdrawn

Primaquine Double Dose for Radical Cure of Plasmodium Vivax in Colombia

Malaria, Vivax | Relapse
Menzies School of Health Research
International Centre for Diarrhoeal Disease Research, Bangladesh; Addis Ababa... and other collaborators

Completed

Reducing the Risk of P. Vivax After Falciparum Infections in Co-endemic Areas (PRIMA)

Malaria | Vivax Malaria | Falciparum Malaria

Ethiopia, Bangladesh, Indonesia
Menzies School of Health Research
Armauer Hansen Research Institute, Ethiopia

Withdrawn

A Trial on Supervised Primaquine Use in Ethiopia (SPRUE)

Malaria
Ulrika Morris
Uppsala University; University of California, San Francisco; RTI International; Mahidol Oxford Tropical Medicine Research Unit and other collaborators

Completed

Effectiveness of Mass Drug Administration for Reducing Seasonal Malaria Transmission in Zanzibar (MaDrAZ)

Malaria | Plasmodium Infections

Tanzania
Menzies School of Health Research
World Health Organization; Walter and Eliza Hall Institute of Medical Research and other collaborators

Unknown

Safety and Efficacy of Primaquine for P. Vivax

Malaria

Solomon Islands, Vanuatu
London School of Hygiene and Tropical Medicine
HealthNet TPO

Completed

Eight Week Primaquine Regimen for the Treatment of Vivax Malaria

Malaria | Vivax Malaria
University of Oxford
Mahidol Oxford Tropical Medicine Research Unit; Faculty of Tropical Medicine...

Not yet recruiting

A Study to Assess the Availability of Oral Primaquine and Its Inert Metabolite, Carboxyprimaquine, in the Body (PQcPQ)

Healthy | Pharmacokinetic

Thailand
University of Oxford
Mahidol Oxford Tropical Medicine Research Unit

Completed

P.Vivax Treatment Trial (Lao Pv)

Plasmodium Vivax

Lao People's Democratic Republic
London School of Hygiene and Tropical Medicine
Wellcome Trust

Completed

Evaluation of the Gametocytocidal Efficacy and Safety of Primaquine in Uncomplicated Falciparum Malaria in Uganda

Falciparum Malaria

Uganda
Papua New Guinea Institute of Medical Research
University of Oxford; Curtin University; The University of Western Australia; Walter...

Unknown

Investigation of Short Course, High Dose Primaquine Treatment for Liver Stages of Plasmodium Vivax Infection

Plasmodium Vivax

Papua New Guinea
University of Oxford
Mahidol University

Completed

Incidence of Vivax Along the Thai Burma Border (VHC)

Vivax Malaria

Thailand
University of Oxford
Mahidol Oxford Tropical Medicine Research Unit

Withdrawn

Tafenoquine and Primaquine in Colostrum and Breast Milk (TBM)

Healthy Lactating Women

Thailand
Menzies School of Health Research
Aga Khan University; University of Melbourne; Universitas Sumatera Utara; Ethiopian... and other collaborators

Recruiting

Effectiveness of Novel Approaches to Radical Cure With Tafenoquine and Primaquine (EFFORT)

Vivax Malaria | Malaria, Vivax | Plasmodium Vivax | Malaria Relapse

Cambodia, Ethiopia, Indonesia, Pakistan
Papua New Guinea Institute of Medical Research
Swiss Tropical & Public Health Institute; Walter and Eliza Hall Institute of... and other collaborators

Completed

Effect of Liver and Blood-stage Treatment on Subsequent Plasmodium Reinfection and Morbidity

Plasmodium Falciparum Infection | Plasmodium Vivax Infection | Plasmodium Vivax Clinical Episode | Plasmodium Falciparum Clinical Episode

Papua New Guinea
Muhimbili University of Health and Allied Sciences
Karolinska Institutet

Completed

Efficacy and Safety of a Single Low-dose Primaquine for the Clearance of Gametocytes

Plasmodium Falciparum

Tanzania
Menzies School of Health Research
Ministry of Health, Malaysia

Completed

P. Knowlesi Trial of Artesunate-mefloquine Versus Chloroquine (ACT KNOW)

Uncomplicated Plasmodium Knowlesi Malaria

Malaysia
University of Oxford
FHI 360; Oxford University Clinical Research Unit, Vietnam; Shoklo Malaria Research... and other collaborators

Completed

Targeted Chemo-elimination (TCE) of Malaria (TME)

Plasmodium Falciparum Malaria

Thailand, Cambodia, Lao People's Democratic Republic, Myanmar, Vietnam
London School of Hygiene and Tropical Medicine
Medical Research Council Unit, The Gambia

Terminated

Evaluation of the Safety of Primaquine in Combination With Dihydroartemisinin-piperaquine in G6PD Deficient Males in The Gambia (SAFEPRIM-II)

Malaria

Gambia
Centers for Disease Control and Prevention
Ministry of Health, Brazil; Evandro Chagas National Institute of Infectious...

Completed

Efficacy of 3 Regimens of Chloroquine and Primaquine for Treatment of P. Vivax Malaria, Cruzeiro do Sul, Acre, Brazil

Malaria, Vivax | P Vivax

Brazil
David Saunders
National Centre for Parasitology, Entomology and Malaria Control, Cambodia; Royal Cambodian Armed Forces and other collaborators

Suspended

Antimalarial Drug Resistance With Assessment of Transmission Blocking Activity

Uncomplicated Plasmodium Falciparum Malaria

Cambodia
University of Oxford
Mahidol University; Mahidol Oxford Tropical Medicine Research Unit

Terminated

Study of Artemether-lumefantrine, Amodiaquine and Primaquine in Healthy Subjects (ALAQPQ)

Healthy | Pharmacokinetic | Drug Combination

Thailand

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