Search clinical trials for: Cinaciguat (BAY58-2667)

Total 367 results

Bayer

Terminated

BAY58-2667 Dose Finding Trial Investigating Fixed Doses in Patients With Acute Decompensated Chronic Congestive Heart Failure (ADHF) (COMPOSE 1)

Acute Heart Failure

Israel, Italy, Japan, Switzerland, United States, Austria, Germany, Thailand, Romania, Slovenia, Croatia, Serbia, Russian Federation, Finland, Sweden, Poland, Slovakia
Bayer

Terminated

Placebo Controlled, Randomized, Double-blind, Multi-center Study to Investigate the Efficacy and Tolerability of BAY58-2667

Congestive Heart Failure

Spain, Germany, Italy, United States, Canada, Hungary, Israel, Estonia, Slovenia, Croatia, Serbia, Lithuania, Poland, Sweden, Russian Federation, Czech Republic, United Kingdom
Bayer

Terminated

A Phase IIb Study to Investigate the Efficacy and Tolerability of Lower Doses Cinaciguat (25 µg/h, 10 µg/h) Given Intravenously to Patients With Acute Decompensated Chronic Congestive Heart Failure (ADHF) (COMPOSE 2)

Acute Heart Failure

Belgium, France, Argentina, United States, Austria, Mexico, Germany, Philippines, Ireland
Bayer

Terminated

A Phase IIb Study to Investigate the Efficacy and Tolerability of Cinaciguat (150 µg/h, 100 µg/h, 50 µg/h) Given Intravenously to Subjects With Acute Decompensated Chronic Congestive Heart Failure (ADHF) (COMPOSE EARLY)

Heart Failure | Heart Decompensation

Italy, United States, Germany, Spain, Japan, Canada, France, Hungary, Poland, South Africa, Korea, Republic of, Israel, Finland, United Kingdom, Ireland, Czech Republic
Blade Therapeutics

Withdrawn

Healthy Volunteer Study Comparing Tablet and Capsule Formulations

Fibrosis

Australia
Shionogi

Completed

Phase IIb One Year Efficacy and Safety Study of S-2367 in Obese Subjects With Reduced Calorie Diet

Obesity

United States
Bayer

Completed

Safety and Efficacy of Oral BAY85-8501 in Patients With Non-CF (Cystic Fibrosis) Bronchiectasis

Bronchiectasis

Italy, Spain, Germany, United Kingdom, France
Bayer

Completed

Study to Investigate the Effect of the A1 Agonist Capadenoson on Ventricular HR in Patients With Persistent or Permanent Atrial Fibrillation.

Atrial Fibrillation

Germany
Bayer

Completed

Single Dose Group Stratified Study in Renal Impaired and Healthy Aged and Gender Matched Subjects

Anemia

Germany
Bayer

Completed

Combined Single / Multiple Dose Escalation Study in Patients With Renal Anemia Due to CKD (Chronic Kidney Disease)

Anemia

Germany, United Kingdom
Shionogi

Completed

Open-Label Extension (OLE) Study for Safety and Efficacy of Velneperit (S-2367) in Obese Subjects (OLE)

Obesity

United States
Bayer

Recruiting

A Study to Learn More About the Long-term Safety and Effectiveness of Molidustat as a Treatment for Japanese Men and Women With Renal Anemia

Renal Anemia

Japan
Blade Therapeutics

Withdrawn

Safety, Pharmacodynamics, and Pharmacokinetics of Orally Administered BLD-2660 in Subjects With IPF

Idiopathic Pulmonary Fibrosis

United Kingdom
Bayer

Completed

15141 Fixed Dose Correction / naïve and Pre Dialysis (Europe and Asia Pacific) (DIALOGUE 1)

Renal Insufficiency, Chronic | Anemia

Japan, Korea, Republic of, United Kingdom, Hungary, Israel, Spain, Bulgaria, Australia, Germany, Italy, Poland, Romania, Turkey, France
Bayer

Completed

Age and Gender Effects on the Pharmacokinetics of BAY85-3934

Anemia

United States
University Hospital, Ghent

Completed

Comparison of Acute Toxicity and Cost Between Whole Breast Irradiation With Sequential Boost and Simultaneous Integrated Boost After Breast Conserving Surgery. (SeqB vs SIB)

Radiotherapy After Breast Conserving Surgery

Belgium
Bayer

Completed

Radiation Dosimetry, Metabolism, Safety, Tolerability and Positron Emission Tomography/Computed Tomography (PET/CT) Imaging With BAY 85-8050 in Healthy Volunteers and Patients

Neoplasm

Germany
Bayer

Completed

Efficacy/Safety Study to Confirm Iberogast's Efficacy in Patients With Irritable Bowel Syndrome Diagnosed on ROME III Criteria Compared to Placebo

Irritable Bowel Syndrome

Germany
Bayer

Completed

A Pharmacy-based Study to Learn More About How Well Iberogast Works, How it Affects the Body, How it is Used, and User Satisfaction in Patients With Functional and Motility-related (Stomach and Bowel Movement-related) Gastrointestinal Diseases, Including Irritable Bowel Syndrome

Functional and Motility Related Gastrointestinal Disorders Such as Irritable Bowel Syndrome and Functional Dyspepsia

Germany
Bayer

Completed

Dose Escalation Study to Investigate Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BAY85-3934 in Subjects With Chronic Kidney Disease (CKD)

Kidney Diseases

Germany
Shionogi

Completed

Phase IIb One Year Efficacy and Safety Study of S-2367 in Obese Subjects With Initial 6-Week Low Calorie Diet

Obesity

United States
Bayer

Completed

Study to Learn More About the Onset of Effect of Iberogast in Patients Suffering From Abnormal Stomach and Intestine Function

Functional Gastrointestinal Disorders

Germany
Bayer

Completed

Evaluation of ZK 6032924 in Probable Alzheimer's Disease Patients Versus Healthy Volunteers and the Radiation Dosimetry of ZK 6032924 in Healthy Volunteers

Alzheimer's Disease | Positron-Emission Tomography

Netherlands, Sweden
Radius Health, Inc.
Nordic Bioscience A/S

Completed

Phase 2 Study of BA058 (Abaloparatide) Transdermal Delivery in Postmenopausal Women With Osteoporosis

Post Menopausal Osteoporosis

Poland, Denmark, United States, Estonia
Bayer

Completed

Study in Patients Suffering From Heartburn and Backward Flow of Stomach Liquid Into the Esophagus

Functional Gastrointestinal Disorders

Germany
Bayer

Completed

Evaluation of the Neuroinflammation Pattern of BAY85-8102 F-18, DPA-714 in Probable Alzheimers Disease Patients Versus Healthy Volunteers and Radiation Dosimetry of F 18, DPA-714 in Healthy Volunteers

Diagnostic Imaging

Finland, Netherlands
Bayer

Completed

A Pharmacy-based Observational Study to Learn More About Iberogast Advance in the Real-world Setting

Functional Dyspepsia | Irritable Bowel Syndrome | Functional Gastrointestinal Disorders Such as Irritable Bowel Syndrome and Functional Dyspepsia

Germany
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bayer; Dendreon

Completed

Study of Sipuleucel-T W/ or W/O Radium-223 in Men With Asymptomatic or Minimally Symptomatic Bone-MCRPC

Prostate Cancer

United States
Radius Health, Inc.

Completed

Phase 2 Dose-finding Study to Evaluate the Effects of BA058 in the Treatment of Postmenopausal Women With Osteoporosis

Osteoporosis

United States
Hoffmann-La Roche

Completed

Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors (ARROW)

Neoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Neoplasms, Glandular and Epithelial | Endocrine System Diseases | Gastrointestinal Neoplasms | Neoplasms, Germ Cell and Embryonal | Head and Neck Neoplasms | Carcinoma, Non-Small-Cell Lung | Respiratory Tract... and other conditions

France, Spain, United States, Korea, Republic of, United Kingdom, Taiwan, China, Belgium, Singapore, Netherlands, Germany, Italy, Hong Kong
Bayer

Terminated

Efficacy/Safety Pilot Study to Investigate Iberogast N's Efficacy in Mild to Moderate Colitis Ulcerosa Patients

Colitis, Ulcerative

Germany
Blade Therapeutics

Completed

First in Human Study in Healthy Volunteers Followed With Dosing in Participants With Lung or Liver Fibrosis

Fibrosis

Australia
Blade Therapeutics
Clinipace Worldwide

Completed

Safety and Antiviral Activity of BLD-2660 in COVID-19 Hospitalized Subjects

Covid19 | Sars-CoV-2

United States, Brazil
Bayer

Completed

To Investigate Pharmacokinetics (Absorption, Distribution, Elimination), Safety and Tolerability of a Single Oral Dose of 75 mg Molidustat Tablet in Male and Female Subjects Requiring Hemo- or Peritoneal Dialysis Compared to Healthy Subjects

Renal Insufficiency, Chronic

Germany
Bayer

Completed

Maintenance Treatment of Renal Anemia in Dialysis Subjects (MIYABI HD-M)

Renal Insufficiency, Chronic | Anemia

Japan
Numab Therapeutics AG

Recruiting

NM32-2668 in Adult Patients With Selected Advanced Solid Tumors

Renal Cell Carcinoma | Mesothelioma, Malignant | Adenocarcinoma of Lung | Triple Negative Breast Cancer | Endometrial Cancer | Fallopian Tube Carcinoma | Peritoneal Carcinoma | Leiomyosarcoma | Liposarcoma | Ovarian Carcinoma | Adenocarcinoma of the Stomach | Melanoma, Malignant | Adenocarcinoma - Gastroesophageal...

United States
Bayer

Completed

A Study of Molidustat for Maintenance Treatment of Renal Anemia in Non-dialysis Subjects (MIYABI ND-M)

Renal Insufficiency, Chronic | Anemia

Japan
Bayer

Completed

A Study of Molidustat for Correction of Renal Anemia in Dialysis Subjects (MIYABI HD-C)

Renal Insufficiency, Chronic | Anemia

Japan
Bayer

Completed

A Study of Molidustat for Treatment of Renal Anemia in Peritoneal Dialysis Subjects (MIYABI PD)

Renal Insufficiency, Chronic | Anemia

Japan
Bayer
Steigerwald Arzneimittelwerk GmbH

Completed

Study to Learn About Relapse Prevention of Hypericumextract (a Drug Based on the Plant St. John Wort) in Outpatients Suffering From Moderate Depressive Episodes

Moderate Depressive Episodes (Major Depression)
Bayer

Completed

Assess Satisfaction of Patients and Physicians With Results of Yaz Plus Treatment for 13 Cycles

Contraception

Russian Federation
Imperial College London
University of Southern California; Guy's and St Thomas' NHS Foundation Trust; Ipse... and other collaborators

Terminated

A Study to Assess the Ability of a Novel Endocrine Treatment for Breast Cancer, Irosustat, to Slow Down Cancer Growth (IPET)

Breast Neoplasms

United Kingdom
Imperial College London
Cancer Research UK

Completed

A Study of the Safety and Effectiveness of Irosustat When Added to an AI in ER+ve Locally Advanced or Metastatic Breast Cancer. (IRIS)

Metastatic Breast Cancer | Locally Advanced Breast Cancer

United Kingdom
Radius Health, Inc.
Medpace, Inc.

Completed

Study to Evaluate and Compare the PK Profiles of Abaloparatide-SC and Abaloparatide-sMTS in a Cohort of Healthy Men and Healthy Women.

Healthy Volunteers

United States
Bayer

Completed

Evaluation of the Positron Emission Tomography (PET) Tracer ZK 6032924 in Patients With Multiple Sclerosis Compared to Healthy Volunteers

Multiple Sclerosis | Positron-Emission Tomography

Australia, Sweden
Bayer

Completed

Long Term Extension Study for the Maintenance Treatment of Anemia Associated With Chronic Kidney Disease (CKD) in Hemodialysis Subjects on Epoetin Alfa / Beta Treatment Versus BAY85-3934 (DIALOGUE5)

Renal Insufficiency, Chronic | Anemia

United States, Japan
Bayer

Completed

Evaluation of Bay 59-8862 in Patients With Aggressive, Refractory Non-Hodgkin's Lymphoma

Lymphoma, Non-Hodgkin

Canada, France, Germany, United States, Netherlands, United Kingdom
Bayer

Completed

Alpharadin™ (Radium-223 Chloride) Safety and Dosimetry With HRPC That Has Metastasized to the Skeleton

Prostate Cancer | Pharmacokinetics | Metastases

United States
Bayer
Janssen Research & Development, LLC

Completed

Exploring the Efficacy and Safety of Rivaroxaban to Support Elective Percutaneous Coronary Intervention (X-PLORER)

Coronary Artery Disease | Cardiovascular Disease

Belgium, Netherlands
Bayer

Completed

A Local Retrospective Observational Study to Evaluate the Treatment Patterns of mCRPC Patients in Belgium Treated With Radium-223 (BELFIGO)

Prostatic Neoplasms, Castration-Resistant

Belgium

3

Subscribe