Search clinical trials for: Clofazimine

Total 37 results

Kaiser Permanente
Health Resources and Services Administration (HRSA)

No longer available

Treatment Protocol for Clofazamine in the Long Term Treatment of Leprosy

Leprosy

United States
Novartis Pharmaceuticals

Available

Lamprene Multiple Patient Program

Non-Tuberculous Mycobacterial (NTM) Infections

United States, Canada
University of Washington
Bill and Melinda Gates Foundation; University of Virginia; The Emmes Company,... and other collaborators

Terminated

A Phase 2A Evaluation of the Safety, Tolerability, Pharmacokinetics, Efficacy of Clofazimine (CFZ) in Cryptosporidiosis

Cryptosporidiosis

Malawi
Global Alliance for TB Drug Development

Completed

Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With Clofazimine (C)-TMC207 (J)-PA-824 (Pa)-Pyrazinamide (Z) (NC-003)

Pulmonary Tuberculosis

South Africa
National Institute of Allergy and Infectious Diseases...

Recruiting

Linezolid Dosing Strategies in Drug-Resistant TB

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant

Brazil, India, Kenya, Philippines, South Africa, Zimbabwe, Thailand, Haiti, Peru, Botswana
National Institute of Allergy and Infectious Diseases...
University of Miami; Children's National Health System

Recruiting

Study of Mycobacterial Infections

Mycobacterium Infections

United States
University of California, San Francisco

Completed

A Randomized Controlled Prophylactic Study of Clofazimine To Prevent Mycobacterium Avium Complex Infection in HIV Disease

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Radboud University Medical Center

Completed

Pharmacokinetic Study With a Loading Dose of Clofazimine in Adult Patients With Nontuberculous Mycobacterial Disease (C-LOAD)

Nontuberculous Mycobacterial Diseases

Netherlands
Paul Saunderson

Completed

Effect of Additional Clofazimine on Erythema Nodosum Leprosum (ENL) Reactions in Leprosy

Lepromatous Leprosy | Borderline Lepromatous Leprosy

Philippines
Medstar Health Research Institute

Withdrawn

Treatment of Crohn's Disease With an Antibiotic Regimen Directed Against Mycobacterium Avium Paratuberculosis

Crohn's Disease
Oregon Health and Science University
National Institute of Allergy and Infectious Diseases (NIAID); National Heart... and other collaborators

Recruiting

Clofazimine in the Treatment of Pulmonary Mycobacterium Avium Complex (MAC)

Mycobacterium Avium Complex

United States
RedHill Biopharma Limited

Active, not recruiting

RHB-204 for the Treatment of Pulmonary Mycobacterium Avium Complex Disease (CleaR-MAC)

Lung Diseases | Bronchiectasis | Pulmonary Mycobacterium Avium Complex Infection

United States
Médecins Sans Frontières, France
Harvard Medical School (HMS and HSDM); Institute of Tropical Medicine, Belgium and other collaborators

Active, not recruiting

Evaluating Newly Approved Drugs in Combination Regimens for Multidrug-Resistant TB With Fluoroquinolone Resistance (endTB-Q) (endTB-Q)

Bacterial Infections | Gram-Positive Bacterial Infections | Tuberculosis | Tuberculosis, Multidrug-Resistant | Pulmonary Tuberculoses | Mycobacterial Infections

Vietnam, Pakistan, India, Kazakhstan, Lesotho, Peru
RedHill Biopharma Limited

Completed

Open Label Efficacy and Safety of Anti-MAP (Mycobacterium Avium Ssp. Paratuberculosis) Therapy in Adult Crohn's Disease (MAPUS2)

Crohn Disease

United States, Canada, Czechia, Israel, New Zealand, Poland, Serbia
University of Brasilia
Ministry of Health, Brazil; Conselho Nacional de Desenvolvimento Científico... and other collaborators

Completed

Uniform Multidrug Therapy Regimen for Leprosy Patients (U-MDT)

Leprosy

Brazil
The University of Hong Kong

Unknown

Dual Therapy With Interferon Beta-1b and Clofazimine for COVID-19

COVID-19

China
Abbott

Completed

The Safety and Effectiveness of Clarithromycin Plus Ethambutol Used With or Without Clofazimine in the Treatment of MAC in Patients With AIDS

HIV Infections | Mycobacterium Avium-intracellular Infection

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Active, not recruiting

Clofazimine- and Rifapentine-Containing Treatment Shortening Regimens in Drug-Susceptible Tuberculosis: The CLO-FAST Study

HIV | Tuberculosis

Haiti, Zimbabwe, Malawi, South Africa, India
Wits Health Consortium (Pty) Ltd
University of Cape Town; Perinatal HIV Research Unit of the University of the... and other collaborators

Active, not recruiting

Building Evidence for Advancing New Treatment for Rifampicin Resistant Tuberculosis (RR-TB) Comparing a Short Course of Treatment (Containing Bedaquiline, Delamanid and Linezolid) With the Current South African Standard of Care

Tuberculosis | Multi Drug Resistant Tuberculosis | Rifampicin Resistant Tuberculosis | Extensively Drug-Resistant Tuberculosis | Pre-XDR-TB

South Africa
National Institute of Allergy and Infectious Diseases...

Completed

Study of Four Different Treatment Approaches for Patients Who Have Mycobacterium Avium Complex Disease (MAC) Plus AIDS

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Huashan Hospital

Active, not recruiting

Refining MDR-TB Treatment (T) Regimens (R) for Ultra(U) Short(S) Therapy(T)-PLUS (TB-TRUSTplus)

Multidrug Resistant Tuberculosis

China
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University of Liverpool; Ministry... and other collaborators

Recruiting

Economic Evaluation of New MDR TB Regimens (PRACTECAL-EE)

Multi-drug Resistant Tuberculosis | Pulmonary Tuberculoses | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa, Uzbekistan
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University of Sussex; Ministry... and other collaborators

Recruiting

Patient-reported Experiences and Quality of Life Outcomes in the TB-PRACTECAL Clinical Trial (PRACTECAL-PRO)

Multidrug Resistant Tuberculosis

Belarus, South Africa, Uzbekistan
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Active, not recruiting

PRACTECAL-PKPD Sub Study (PRACTECAL-PKPD)

Multi-drug Resistant Tuberculosis | Pulmonary Tuberculosis | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa
Boston University
Harvard Medical School (HMS and HSDM); University of Colorado, Denver; National... and other collaborators

Recruiting

Efficacy and Tolerability of Bedaquiline, Delamanid, Levofloxacin, Linezolid, and Clofazimine to Treat MDR-TB (DRAMATIC)

Tuberculosis, Multidrug-Resistant

Philippines, Vietnam
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Active, not recruiting

Pragmatic Clinical Trial for a More Effective Concise and Less Toxic MDR-TB Treatment Regimen(s) (TB-PRACTECAL)

Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa, Uzbekistan
Beijing Chest Hospital

Recruiting

A Study of an Oral Short-course Regimen Including Bedaquiline for the Treatment of Participants With Multidrug-resistant Tuberculosis in China (PROSPECT)

Tuberculosis, Multidrug-Resistant

China
Médecins Sans Frontières, France
Harvard Medical School (HMS and HSDM); Institute of Tropical Medicine, Belgium and other collaborators

Completed

Evaluating Newly Approved Drugs for Multidrug-resistant TB (endTB)

Tuberculosis, Multidrug-Resistant | Infection, Bacterial | Pulmonary Tuberculoses

Pakistan, Georgia, India, Kazakhstan, Lesotho, Peru, South Africa
Brigham and Women's Hospital
University of California, Los Angeles; University of Stellenbosch; University... and other collaborators

Recruiting

Ultra-Short Course Bedaquiline, Clofazimine, Pyrazinamide and Delamanid Versus Standard Therapy for Drug-Susceptible TB (PRESCIENT)

HIV | Tuberculosis, Pulmonary

South Africa, Haiti
National Institute of Allergy and Infectious Diseases...

Completed

A Phase II/III Trial of Rifampin, Ciprofloxacin, Clofazimine, Ethambutol, and Amikacin in the Treatment of Disseminated Mycobacterium Avium Infection in HIV-Infected Individuals.

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Beijing Chest Hospital
National Medical Center for Infectious Diseases

Recruiting

Innovating Shorter, All- Oral, Precised, Individualized Treatment Regimen for Rifampicin Resistant Tuberculosis：Contezolid, Delamanid and Bedaquiline Cohort (INSPIRE-CODA)

Pulmonary Tuberculosis | Rifampicin-resistant Tuberculosis

China
The University of Queensland
University of Copenhagen; Erasmus Medical Center; Monash University; Hôpital Cochin and other collaborators

Recruiting

Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT)

Pulmonary Disease Due to Mycobacteria (Diagnosis)

Australia, Canada, Denmark, France, Ireland, Netherlands, New Zealand, United Kingdom, Singapore
IUATLD, Inc
Medical Research Council; Institute of Tropical Medicine, Belgium; Liverpool... and other collaborators

Completed

The Evaluation of a Standard Treatment Regimen of Anti-tuberculosis Drugs for Patients With MDR-TB (STREAM)

MDR-TB

Ethiopia, Georgia, India, Moldova, Republic of, Mongolia, South Africa, Uganda
University College, London
National University Hospital, Singapore; Singapore Clinical Research Institute...

Completed

Two-month Regimens Using Novel Combinations to Augment Treatment Effectiveness for Drug-sensitive Tuberculosis (TRUNCATE-TB)

Tuberculosis, Pulmonary

Singapore, Uganda, Thailand, Indonesia, Philippines, India
Beijing Children's Hospital
Hopital Universitaire Robert-Debre; Shandong University; Rennes University Hospital

Recruiting

Population Pharmacokinetics of Anti-tuberculosis Drugs in Children With Tuberculosis

Tuberculosis

China
National Institute of Allergy and Infectious Diseases...

Completed

A Prospective Study of Multidrug Resistance and a Pilot Study of the Safety of and Clinical and Microbiologic Response to Levofloxacin in Combination With Other Antimycobacterial Drugs for Treatment of Multidrug-Resistant Pulmonary Tuberculosis (MDRTB) in HIV-Infected Patients.

HIV Infections | Tuberculosis

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy

HIV Infections

United States, Puerto Rico, Thailand, Botswana, Argentina, Brazil, Tanzania, South Africa

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