Search clinical trials for: Colesevelam HCl

Total 2805 results

Daiichi Sankyo, Inc.

Completed

Effects of Metformin Hydrochloride (HCl) in Combination With Colesevelam HCl, Compared to Metformin HCl Alone, in Patients With Type 2 Diabetes Mellitus and the Effects of Colesevelam HCl on Lipids and Glucose on Pre-diabetic Patients.

Type 2 Diabetes Mellitus | Hypercholesterolemia | Pre-diabetes

United States, Colombia, India, Mexico
Seattle Institute for Biomedical and Clinical Research
VA Puget Sound Health Care System

Completed

Study to Evaluate the Effects of Colesevelam on Insulin Sensitivity and ß-Cell Function in Subjects With Impaired Fasting Glucose (Prediabetes)

Prediabetes | Impaired Fasting Glucose
Daiichi Sankyo, Inc.

Completed

A Study to Determine the Effect of WelChol Tablets on Cholesterol in Patients Who Have Been Taking Atorvastatin for at Least 4 Weeks.

Hypercholesterolemia

United States
Daiichi Sankyo, Inc.

Completed

A Study to Determine the Effect of WelChol Tablets on Cholesterol in Patients Who Have Been Taking Simvastatin for at Least 4 Weeks.

Hypercholesterolemia

United States
University of Colorado, Denver
Daiichi Sankyo, Inc.

Completed

Efficacy of Colesevelam in Subjects With Type 1 Diabetes Mellitus

Diabetes Mellitus, Type 1 | Hyperlipidemias

United States
KineMed
University Medical Center Groningen; Daiichi Sankyo, Inc.; Diabetes & Glandular...

Completed

Effects of Colesevelam HCl On Bile Acid Kinetics

Type 2 Diabetes Mellitus | Impaired Glucose Tolerance

United States
Daiichi Sankyo, Inc.

Completed

Efficacy and Safety of Colesevelam in Pediatric Patients With Genetic High Cholesterol

Hypercholesterolemia

United States, South Africa, Israel, Netherlands, Canada, Norway, Austria, Australia
University of California, San Diego
Daiichi Sankyo, Inc.

Completed

Colesevelam Versus Placebo in the Treatment of Nonalcoholic Steatohepatitis

Nonalcoholic Steatohepatitis

United States
HealthPartners Institute
Daiichi Sankyo, Inc.; International Diabetes Center at Park Nicollet

Completed

Glycemic Effect of Colesevelam HCl (Welchol) in Patients With Type 2 Diabetes

Type 2 Diabetes

United States
Carine Beysen

Completed

Mechanisms of Glucose Lowering Effect of Colesevelam HCl

Diabetes

United States
Louisville Metabolic and Atherosclerosis Research...
Daiichi Sankyo, Inc.; Provident Clinical Research

Completed

Comparison of Colesevelam Hydrogen Chloride (HCl) Powder For Oral Suspension Versus Generic Cholestyramine Through Use of the Bile Acid Sequestrant Acceptability (BASA) Scale

Healthy

United States
Daiichi Sankyo, Inc.

Completed

Study to Compare Welchol and TriCor to TriCor Alone in Patients With High Cholesterol

Hypercholesterolemia | Hyperlipidemia, Familial Combined

United States
Daiichi Sankyo, Inc.

Completed

Colesevelam for Children With Type 2 Diabetes (WELKid DM)

Type 2 Diabetes Mellitus

United States
Daiichi Sankyo, Inc.

Completed

Long-Term Study of Safety and Efficacy of WelChol® as an Additional Therapy in Patients With Type 2 Diabetes

Type 2 Diabetes

United States, Peru, Mexico
KineMed

Completed

The Effects of Co-admin of Colesevelam and Sitagliptin on Glucose Metabolism in Subjects With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
University Hospital, Gentofte, Copenhagen

Completed

Effect of Bile Acids on GLP-1 Secretion

Obesity | Type 2 Diabetes

Denmark
Daiichi Sankyo, Inc.

Completed

Effects of Colesevelam on How the Body Responds to Insulin in Patients With Type 2 Diabetes

Type 2 Diabetes

United States
Daiichi Sankyo, Inc.

Completed

WelChol® With Metformin in Treating Patients With Type 2 Diabetes

Type 2 Diabetes

United States, Peru, Mexico
Foundation for Liver Research

Completed

Colesevelam Versus Placebo in Cholestatic Pruritus (COPE)

Chronic Liver Disease

Netherlands
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Trial to Understand Efficacy of Colesevelam in Diarrhea Predominant IBS Patients With Bile Acid Malabsorption

Irritable Bowel Syndrome With Diarrhea | Bile Acid Malabsorption | Chronic Diarrhea

United States
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Ability of Mayo Clinic High-performance Liquid Chromatography (HPLC) Method to Measure Fecal Bile Acids

Diarrhea Predominant Irritable Bowel Syndrome

United States
University of Manitoba

Unknown

Effects of Fish Oil and Colesevelam (STAIR7007)

Sitosterolemia

Canada
Daiichi Sankyo, Inc.

Completed

WelChol® and Sulfonylurea in Treating Patients With Type 2 Diabetes

Type 2 Diabetes

United States, Peru, Mexico
St. Boniface Hospital

Not yet recruiting

Impact of Therapy Using Colesevelam Treatment Reducing Bile Acids in Patients With Fontan Circulation. (MYSTIC)

Fontan Circulation
Memorial Sloan Kettering Cancer Center

Active, not recruiting

A Study of Colesevelam for Lenalidomide-Associated Diarrhea

Diarrhea | Multiple Myeloma

United States
Florian Beigel

Terminated

Colesevelam for the Treatment of Bile Acid Malabsorption in Patients With Crohn's Disease (COBAM)

Crohns Disease | Bile Acid Malabsorption

Germany
Daiichi Sankyo, Inc.

Completed

Effects on Colesevelam HC1 (WelChol®) on Insulin Sensitivity in Subjects With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Hvidovre University Hospital
University of Copenhagen

Completed

Effects of Bile Acids and Bile Acid Sequestrants on GLP-1 Secretion After Roux-en-Y Gastric Bypass

Severe Obesity

Denmark
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Does Welchol (Colesevelam Hydrochloride) Improve Colonic Transit in Diarrhea-predominant Irritable Bowel Syndrome (D-IBS)? (welchol)

Irritable Bowel Syndrome | Diarrhea

United States
University Hospital, Gentofte, Copenhagen

Completed

Bileacid Malabsorption and GLP-1 Secretion

Bileacid Malabsorption

Denmark
Hvidovre University Hospital
University of Copenhagen

Completed

Effect of Bile Acids and Bile Acid Sequstrants on GLP-1 Secretion After Roux-en-Y Gastric Bypass

Severe Obesity

Denmark
Daiichi Sankyo, Inc.

Completed

WelChol® and Insulin in Treating Patients With Type 2 Diabetes

Type 2 Diabetes

United States, Peru, Mexico
Daiichi Sankyo, Inc.

Completed

Effects of Colesevelam HCl, Rosiglitazone, Sitagliptin on Control of Blood Glucose and Lipids in Type 2 Diabetes Patients Whose Blood Glucose Isn't Completely Controlled With Metformin

Type 2 Diabetes | Hyperlipidemia

United States
Genzyme, a Sanofi Company

Completed

A Study of the Safety and Efficacy of Patients With Familial Hypercholesterolaemia Taking Colesevelam as add-on Therapy to Their Existing Medication

Familial Hypercholesterolemia

Netherlands, France, Germany, Sweden, United Kingdom
University of Virginia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Diabetes Closed-Loop Project 6 (DCLP6): Fully Automated Closed-Loop Control in Type 1 Diabetes Using Meal Anticipation

Type 1 Diabetes

United States
University Hospital, Gentofte, Copenhagen

Completed

The Role of Metformin and Colesevelam in Human GLP-1 Secretion (ColMetInc)

Type 2 Diabetes

Denmark
Spanish Breast Cancer Research Group
Pierre Fabre Laboratories; Puma Biotechnology, Inc.

Recruiting

Three Antidiarrheal Strategies in HER2+/HR+ Early Breast Cancer Patients Treated With Extended Adjuvant Neratinib (DIANER)

HER2 Positive Breast Cancer | Hormone Receptor Positive | Early-stage Breast Cancer

Spain
Rabin Medical Center
Medtronic; GIF

Completed

An Open-label, Two-center, Randomized, Cross-over Study to Evaluate the Safety and Efficacy of Glycemic Control Using Hybrid-closed Loop vs. Advanced Hybrid Closed-loop in Young Subjects With Type 1 Diabetes

Diabetes Mellitus, Type 1

Germany, Israel
Rabin Medical Center

Completed

Comparison of Two Closed-Loop Strategies for Glucose Control in Type 1 Diabetes The DREMED Trail- 2

Type 1 Diabetes

Israel
University of Washington
National Heart, Lung, and Blood Institute (NHLBI); Pfizer; Daiichi Sankyo, Inc.; Abbo... and other collaborators

Completed

Evaluate Carotid Artery Plaque Composition by Magnetic Resonance Imaging in People Receiving Cholesterol Medication (CPC)

Coronary Artery Disease | Atherosclerosis | Carotid Artery Diseases

United States
LMC Diabetes & Endocrinology Ltd.
Bausch Health Americas, Inc.

Completed

Randomized Trial Comparing Colesevelam vs. Ezetimibe (GOAL-RCT)

Type 2 Diabetes Mellitus

Canada
Genzyme, a Sanofi Company

Completed

A Study to Assess Any Potential Interaction Between Colesevelam and Ciclosporin in Healthy Volunteers

Healthy

Netherlands
National Taiwan University Hospital

Completed

Investigating the Gut Microbiota Modulation Effects of Allicin for Cardiovascular Disease Protection and Establishing Microbiota Directed Personalized Nutrition Guidance With Novel Humanized Gnotobiotic Mice Model, Microbial Culturomics and Metabolomic Technique

Atherosclerosis

Taiwan
Daiichi Sankyo, Inc.

Completed

Colesevelam as Add-on to Pioglitazone Therapy for Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Genzyme, a Sanofi Company
Manipal Acunova Ltd.

Completed

A Multicenter, Active and Placebo-controlled Study of Enteric Coated Sevelamer in Patients With Mild to Moderate Hypercholesteremia (Sevelamer ECS)

Hypercholesterolemia

India
Universidad Complutense de Madrid

Completed

One- Versus Two-Stage Aesthetic Crown Lengthening

Patients in Need of Surgical CL in the Anterior Maxillary Sextant for Restorative Purposes
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Daiichi... and other collaborators

Completed

The Effect of Welchol on Glucose Metabolism in Type 2 Diabetics

Type 2 Diabetes

United States
University of Kansas Medical Center
National Cancer Institute (NCI)

Completed

Acolbifene in Preventing Cancer in Premenopausal Women at High Risk of Breast Cancer

Breast Cancer

United States
Radiant Research

Completed

Colesevelam Treatment for Impaired Fasting Glucose During Niacin Therapy (CERTAIN)

Hyperglycemia | Dyslipidemia | Hyperlipidemia

United States
Acologix, Inc.

Unknown

A Randomized-Withdrawal Phase 3 Study Evaluating the Safety and Efficacy of Oral Nalfurafine HCl (AC-820)in Subjects on Hemodialysis With Uremic Pruritus (Renal Itch) (AC120-8231)

Uremic Pruritus

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