Search clinical trials for: Comparator: Placebo to Aliskiren

Total 2174 results

Merck Sharp & Dohme LLC

Completed

The Effect of Hypertension Medications on Renal Blood Flow Measurements in Healthy Males (MK-0000-127)

Hypertension
Novartis

Completed

Efficacy and Safety of Once Daily Dosing of Aliskiren (300 mg (qd) Once a Day) to Twice Daily Dosing of Aliskiren (150 mg (Bid) Twice a Day) in Treating Moderate Hypertension.

Essential Hypertension

Germany, Spain, United States
Clinical Nutrition Research Center, Illinois Institute...

Completed

Dose-dependent Effect of Grape Seed Extract on Glucose Control in People With Impaired Glucose Tolerance (GSE3)

Impaired Glucose Tolerance

United States
Novartis

Completed

Efficacy and Safety of Aliskiren 300 mg Compared to Telmisartan 80 mg After 1 Week of Treatment Withdrawal (ASSERTIVE)

Hypertension

Brazil, Canada, Ecuador, Germany, Hungary, Korea, Republic of, Malaysia, Mexico, Panama, Philippines, Singapore, Slovakia, Spain, Turkey, United Kingdom, Venezuela
Novartis

Completed

Study to Evaluate the Efficacy and Safety of Combination Aliskiren/Amlodipine in Patients Not Adequately Responding to Aliskiren Alone

Hypertension

Estonia, France, Iceland, India, Italy, Korea, Republic of, Lithuania, Spain, Venezuela
Novartis

Completed

A Study Evaluating the Gastrointestinal (GI) Safety and Tolerability of Aliskiren Compared to Ramipril in Essential Hypertension

Hypertension

United States, Argentina, Colombia, France, Germany, India, Spain
Novartis

Completed

Efficacy and Safety of Aliskiren in Patients With Mild to Moderate Hypertension During Exercise

Hypertension

Singapore, Hungary, Czech Republic, United Kingdom
Merck Sharp & Dohme LLC

Completed

A Study to Test Once-Weekly Doses of Odanacatib (MK0822) on Healthy Adult Females (0822-005)(COMPLETED)

Osteoporosis
Merck Sharp & Dohme LLC

Terminated

A Single-Dose Study of MK6349 in Patients With Type 2 Diabetes (6349-002)

Type 2 Diabetes Mellitus
Novartis

Completed

Efficacy and Safety of Aliskiren 75 mg, 150 mg, and 300 mg in Elderly Patients With Essential Hypertension When Given With a Light Meal in a 8 Week Placebo-controlled Study

Hypertension

Slovakia, Italy, Netherlands, Argentina, Germany, Poland, Czech Republic, Iceland
Novartis

Completed

Efficacy of Aliskiren Compared to Ramipril in the Treatment of Moderate Systolic Hypertensive Patients (ALIAS)

Essential Hypertension

France
Aswan University Hospital

Unknown

Triple Tourniquets With or Without Tranexamic Acid for Reducing Blood Loss at Open Myomectomy (TTT)

Myoma

Egypt
Novartis Pharmaceuticals

Terminated

Aliskiren Trial in Type 2 Diabetes Using Cardiovascular and Renal Disease Endpoints (Core and Extension Phases) (ALTITUDE)

Cardiovascular Disease | Type 2 Diabetes Mellitus

Spain, China, United States, Belgium, Colombia, South Africa, Italy, United Kingdom, Germany, Hungary, Japan, Taiwan, Turkey, Netherlands, Greece, Switzerland, Austria, France, Thailand, Argentina, Canada, Singapore, Lithuania, Sweden, ... and more
Novartis Pharmaceuticals

Completed

Effects of Aliskiren, Ramipril, and the Combination on Levels of Angiotensin II in Patients With Decompensated Systolic Heart Failure (ESCAPE-SHF)

Heart Failure

Russian Federation, Germany, Poland
Christiana Care Health Services

Completed

The Effect of Renin Inhibition on Nerve Function in Diabetes

Diabetes

United States
Novartis Pharmaceuticals
The Cleveland Clinic

Completed

Safety and Efficacy of Aliskiren on the Progression of Atherosclerosis in Coronary Artery Disease Patients (AQUARIUS)

Coronary Artery Disease (CAD) | Coronary Atherosclerosis

Italy, Spain, Hungary, Australia, United States, Belgium, Canada, Germany, France, Argentina, Poland
Wake Forest University Health Sciences
Novartis Pharmaceuticals

Completed

Effects of Aliskiren on Patient With Heart Failure and a Normal Ejection Fraction (Aliskiren)

Heart Failure

United States
Novartis Pharmaceuticals

Terminated

Efficacy of Aliskiren in the Treatment of Diabetic Macular Edema

Diabetic Macular Edema

Denmark, United States
Aswan University Hospital

Unknown

Carbetocin Versus Oxytocin Infusion Plus Tranexamic Acid During Cesarean Section

Cesarean Section Complications

Egypt
Vanderbilt University Medical Center

Completed

The Effects of Renin Inhibition on Fibrinolytic Balance and Endothelial Function

High Blood Pressure

United States
Novartis Pharmaceuticals

Completed

Six Months Efficacy and Safety of Aliskiren Therapy on Top of Standard Therapy, on Morbidity and Mortality in Patients With Acute Decompensated Heart Failure (ASTRONAUT)

Acute Decompensated Heart Failure | Congestive Heart Failure

Colombia, Czech Republic, India, Italy, Belgium, Turkey, Argentina, France, Germany, Israel, Spain, Canada, Taiwan, United States, Singapore, Russian Federation, Philippines, Slovakia, Sweden, Hungary, Finland, Poland, Romania, Brazil
Aswan University Hospital

Unknown

Foley's Catheter Balloon Plus Tranexamic Acid During Cesarean Delivery for Placenta Previa

Placenta Previa

Egypt
Brigham and Women's Hospital
Novartis

Terminated

Effect of Short Term Aliskiren Treatment in Kidney Transplant Patients

Kidney Failure, Chronic | Kidney Disease

United States
hany farouk

Unknown

Buccal Misoprostol and Intravenous Tranexamic Acid During Emergent Cesarean Delivery

Cesarean Section Complications

Egypt
Mayo Clinic
National Heart, Lung, and Blood Institute (NHLBI); Novartis; National Institute...

Terminated

The Effect of Tekturna on Endothelial Function and Endothelial Progenitor Cells in Patients With Early Atherosclerosis

Endothelial Dysfunction

United States
Aswan University Hospital

Unknown

Role of 200 mg Versus 400mg Vaginal Progesterone in Prevention of Preterm Labor in Twin Gestation

Twin; Pregnancy, Affecting Fetus or Newborn

Egypt
Merck Sharp & Dohme LLC

Completed

Three-Dose Regimen of MRKAd5+6 Trigene (V526) in Healthy Adults (V526-001)(COMPLETED)

HIV Infections | HIV
Novartis

Completed

Hemodynamic Effects of Aliskiren Compared to Captopril on the Kidney in Healthy Volunteers on a Low- and High- Sodium Diet

Hypertension

United States
Merck Sharp & Dohme LLC

Completed

A Study of a Bivalent Influenza Peptide Conjugate Vaccine in Healthy Adults

Influenza
University Medical Center Groningen

Terminated

Safety and Efficacy Study of Add On Aliskiren in Patients With Heart Failure and Renal Impairment (ARIANA-CHF-RD)

Heart Failure | Kidney Failure

Netherlands
Novartis

Completed

Safety and Efficacy of Aliskiren in Post Myocardial Infarction Patients (ASPIRE)

Myocardial Infarction

United States, Argentina, Belgium, Canada, Colombia, Czech Republic, Denmark, Germany, Hungary, India, Israel, Italy, Korea, Republic of, Netherlands, Norway, Poland, Russian Federation, Slovakia, Spain, Sweden, Turkey, United Kingdom and more
Aswan University Hospital

Unknown

Sublingual Misoprostol and Tranexamic Acid in Pregnant Women With Twin Pregnancy Undergoing Cesarean Section

Cesarean Section Complications

Egypt
Ohio State University
Novartis

Terminated

Aliskiren Effect on Aortic Plaque Progression (ALPINE)

Atherosclerosis

United States
Aswan University Hospital

Unknown

17-Alpha-Hydroxyprogesterone Caproate in Pregnant Women With Placenta Previa

Placenta Previa

Egypt
Vitae Pharmaceuticals, Inc.
Brigham and Women's Hospital

Completed

Direct Renin Inhibition and the Kidney

Renal Function

United States
Beth Israel Deaconess Medical Center
Novartis Pharmaceuticals

Completed

The Effect of Aliskiren on Endothelial Function in Pre-Diabetes and Diabetes

Diabetes Type 2

United States
Chinese University of Hong Kong

Completed

Aliskiren for Immunoglobulin A (IgA) Nephropathy

IgA Nephropathy

Hong Kong
Novartis Pharmaceuticals

Terminated

Assessment of Aliskiren/Amlodipine and Amlodipine on Ankle Foot Volume (AFV) in Patients With Hypertension

Hypertension | Ankle Edema

Netherlands
Merck Sharp & Dohme LLC

Completed

The Effect of MK0859 on Lipoprotein Metabolism in Patients With Dyslipidemia (0859-026 AM3)

Dyslipidemia
Merck Sharp & Dohme LLC

Withdrawn

Study to Evaluate Different Regimens of Vaniprevir (MK7009) for the Treatment of Chronic Genotype 1 Hepatitis C Virus Infection in Treatment-naive Patients (MK-7009-019)(WITHDRAWN)

Chronic Genotype 1 Hepatitis C Virus Infection
Novartis Pharmaceuticals

Terminated

To Study the Effects of Aliskiren on Albuminuria and Various Biomarkers in Patients With Nephropathy (ARIA)

Non-diabetic Nephropathy

Netherlands
National Taiwan University Hospital
Taipei Veterans General Hospital, Taiwan

Unknown

Add-on Aliskiren Treatment in Patients With Chronic Congestive Heart Failure

Congestive Heart Failure

Taiwan
Vyne Therapeutics Inc.

Terminated

A Study of MK0594 in Patients With Alcohol Dependence (0594-020)

Alcohol Dependence
Wayne State University
Novartis

Unknown

Vitamin D Augmentation of Tekturna (Aliskiren) in Hypertension (VDATH)

Hypertension

United States
Novartis

Completed

Efficacy and Safety of SPA100 (Fixed-dose Combination of Aliskiren/Amlodipine) in Patients With Essential Hypertension

Essential Hypertension

Japan
Organon and Co

Completed

To Evaluate Ezetimibe/Simvastatin and Niacin (Extended Release Tablet) in Patients With Type IIa or Type IIb Hyperlipidemia (0653A-091)(COMPLETED)

Hypercholesterolemia
Merck Sharp & Dohme LLC

Completed

Sitagliptin and Pioglitazone Mechanism of Action Study in Type 2 Diabetes Mellitus (0431-061)

Type 2 Diabetes Mellitus (T2DM)
University of Alabama at Birmingham
Novartis

Terminated

Effect of the Direct Renin Inhibitor Aliskiren on Endothelial Function and Arterial Stiffness in Diabetic Subjects

Hypertension | Diabetes | Pre-hypertension

United States
Aswan University Hospital

Unknown

Topical Tranexamic Acid Plus Perivascular Vasopressin at the Time of Abdominal Myomectomy

Myoma

Egypt
Eisai Inc.

Completed

A Randomized, Double-blind, Placebo-controlled, Combined Single Ascending Dose and Multiple Ascending Dose Study

Alzheimer's Disease

United States

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