Search clinical trials for: Coxsackievirus A21

Total 1221 results

Viralytics

Completed

Intratumoural Administration of Coxsackievirus A21 for the Control of Malignant Melanoma (PXS-X02) (PXS-X02)

Malignant Melanoma

Australia
Viralytics

Completed

A Safety Study of Two Intratumoural Doses of Coxsackievirus Type A21 in Melanoma Patients (PSX-X03)

Stage IV Melanoma

Australia
Viralytics

Completed

A Study of Intratumoral CAVATAK™ in Patients With Stage IIIc and Stage IV Malignant Melanoma (VLA-007 CALM ) (CALM)

Malignant Melanoma

United States
Viralytics

Terminated

A Study of the Intratumoural Administration of CAVATAK to Head and Neck Cancer Patients (VLA-X06) (VLA-X06)

Head and Neck Cancer

Australia
Viralytics

Completed

Intratumoral CAVATAK (CVA21) and Pembrolizumab in Patients With Advanced Melanoma (VLA-011 CAPRA) (CAPRA)

Melanoma

United States
Viralytics

Completed

CAVATAK® and Ipilimumab in Uveal Melanoma Metastatic to the Liver (VLA-024 CLEVER) (CLEVER)

Liver Metastases | Uveal Melanoma

United States
Viralytics
Providence Health & Services

Completed

Intratumoral CAVATAK (CVA21) and Ipilimumab in Patients With Advanced Melanoma (VLA-013 MITCI) (MITCI)

Melanoma

United States
Viralytics

Completed

CAVATAK (CVA21) in Non-muscle Invasive Bladder Cancer (VLA-012 CANON) (CANON)

Non-muscle Invasive Bladder Cancer

United Kingdom
Merck Sharp & Dohme LLC

Terminated

A Study of Gebasaxturev (V937) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Solid Tumors (V937-013)

Neoplasm Metastasis

United States, Canada, France, Germany, Hungary, Israel, Italy, Japan, Norway, Peru, Poland, Portugal, Spain, Taiwan
Merck Sharp & Dohme LLC

Terminated

Efficacy, Safety, and Tolerability of Gebasaxturev (V937) Administered Intravenously or Intratumorally With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone in Participants With Advanced/Metastatic Melanoma (V937-011)

Advanced/Metastatic Melanoma

United States, Australia, Chile, France, Germany, Israel, Italy, Korea, Republic of, Norway, South Africa, Spain
University of Reading

Completed

Effects of A2 Milk on Gastrointestinal Function in Non-lactose Milk Intolerance

Milk Intolerance

United Kingdom
Institut Pasteur de Lille

Completed

Milk Consumption on Digestive Comfort. (A2-DIGEST)

Healthy Volunteers

France
Merck Sharp & Dohme LLC

Active, not recruiting

Substudy 02C: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With Stage III Melanoma Who Are Candidates for Neoadjuvant Therapy (MK-3475-02C/KEYMAKER-U02)

Melanoma

United States, Australia, France, Israel, Italy, Switzerland
Seoul National University Bundang Hospital

Active, not recruiting

Evaluation of the Efficacy and Safety of A2 Milk on Digestion

Digestive Discomfort

Korea, Republic of
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of a Vaccine in Combination With Beta-glucan in People With Neuroblastoma

Neuroblastoma | High-risk Neuroblastoma | Metastatic Neuroblastoma

United States
Vicore Pharma AB
SGS Life Sciences, a division of SGS Belgium NV

Completed

Cold Challenge With C21 in RP

Systemic Sclerosis | Raynaud Phenomenon

United Kingdom
a2 Milk Company Ltd.

Completed

Incidence of Lactose Intolerance Among Self-reported Lactose Intolerant People

Lactose Intolerance
Thuasne

Recruiting

Contribution of an Off-the-shelf Carbon Ankle Foot Orthosis (AFO) in the Management of Walking Functional Impairment (DEFISTEP)

Neuropathy (Disorder)

France
University of Pittsburgh

Completed

Effects of an 8-day Advanced Meditation, Samyama on Physical, Psychological and Spiritual Wellbeing ,and Associated Neural Mechanisms

Depression | Stress | Inflammatory Bowel Diseases | Dietary Habits | Mental Health Wellness 1 | Happiness | Consciousness, Level Altered | Ecstasy

United States
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of a Vaccine in Combination With β-glucan and GM-CSF in People With Neuroblastoma

Neuroblastoma

United States
Northumbria University
ESPA Research; a2 Milk Company Ltd.

Completed

a2 Milk for Autism and Attention-deficit Hyperactivity Disorder (ADHD) (A2MT)

Autism Spectrum Disorder | Attention Deficit Hyperactivity Disorder | Autism

United Kingdom
Bayer

Completed

Study on the Safety of Drug BAY2586116 and How it Works in Patients With Obstructive Sleep Apnea (a Sleep Disorder Caused by the Narrowing and Collapse of the Airway During Sleep) Including the Blood Level of the Drug and Effect of Its Doses and Routes of Administration (KOALA)

Sleep Apnea, Obstructive

Australia
Scorpion Therapeutics, Inc.

Recruiting

First-In-Human Study of STX-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR Exon 20 Insertion Mutations

Non-Small Cell Lung Cancer | NSCLC | EGFR/HER2 Exon 20 Insertion Mutation

United States, Taiwan
Arcturus Therapeutics, Inc.

Completed

Ascending Dose Study of Investigational SARS-CoV-2 Vaccine ARCT-021 in Healthy Adult Subjects

SARS-CoV-2

Singapore
Valeant Pharmaceuticals

Unknown

A Study Comparing the Efficacy and Safety of IDP-121 and IDP-121 Vehicle Lotion in the Treatment of Acne Vulgaris

Acne Vulgaris
Samsung Electronics
Nexus DX

Terminated

Evaluation of the Samsung LABGEO IVD-A20 CHF Test in a Point-of-Care Setting

Congestive Heart Failure

United States
Vertex Pharmaceuticals Incorporated

Active, not recruiting

Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age

Cystic Fibrosis

United States, Australia, Germany, Sweden, Switzerland, France, Netherlands, United Kingdom
Vertex Pharmaceuticals Incorporated

Active, not recruiting

A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy

Cystic Fibrosis

United States, Spain, United Kingdom, Belgium, Netherlands, Denmark, Israel, New Zealand, France, Australia, Ireland, Germany, Sweden, Canada, Czechia, Switzerland, Portugal, Italy, Austria, Hungary, Norway, Poland, Greece
Vertex Pharmaceuticals Incorporated

Completed

Pharmacokinetics and Safety Assessment of VX-121/Tezacaftor/Deutivacaftor in Participants With Moderate Hepatic Impairment

Cystic Fibrosis

United States
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Relative Bioavailability of a Fixed-dose Combination Tablet of VX-121/Tezacaftor/Deutivacaftor

Cystic Fibrosis

United States
MediciNova

Completed

Evaluate the Safety of MN-221 in Subjects With Stable Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United States
National Cancer Institute (NCI)

Completed

Phase II Study of IMC-A12 in Patients With Mesothelioma Who Have Been Previously Treated With Chemotherapy

Peritoneal Mesothelioma | Pleural Mesothelioma

United States
Valeant Pharmaceuticals

Unknown

A Study Comparing the Efficacy and Safety of IDP-121 and IDP-121 Vehicle Lotion in the Treatment of Acne Vulgaris

Acne Vulgaris
Ono Pharmaceutical Co. Ltd

Completed

A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacology of ONO-4474 in Healthy Volunteers

Osteoarthritis

Denmark, United Kingdom
Allarity Therapeutics
Amarex Clinical Research; Alcedis GmbH

Recruiting

Investigation of 2X-121 in Patients With Advanced Ovarian Cancer Selected by the 2X-121 DRP® (PREDICT 2X-121)

Advanced Ovarian Cancer

United Kingdom, United States
Purdue University

Recruiting

Comparing the Adaptation of Commercial Milk and A2 Milk in Lactose Maldigesters

Lactose Intolerance

United States
Purdue University

Recruiting

Comparing the Inflammation, Maldigestion and Symptoms Due to Commercial Milk and A2 Milk

Lactose Intolerance

United States
Nirmish Shah

Recruiting

AB1 in Adult Patients With Sickle Cell Disease (SCD) ((SCD))

Sickle Cell Disease

United States
Purdue University

Completed

Comparing the Gastric Transit of Commercial Milk and A2 Milk

Lactose Intolerance, Adult Type

United States
Kissei Pharmaceutical Co., Ltd.

Completed

A Phase III Study of PA21 in Peritoneal Dialysis Patients With Hyperphosphatemia

Peritoneal Dialysis | Hyperphosphatemia

Japan
H. Lundbeck A/S

Completed

Study Investigating the Safety, Tolerability, and Pharmacokinetic Properties of Lu AE58054 in Healthy Japanese and Caucasian Subjects

Healthy

United Kingdom
AJU Pharm Co., Ltd.

Completed

Efficacy and Safety of AJU-A51 in Type 2 Diabetes Mellitus Patients

Type2 Diabetes

Korea, Republic of
Kala Pharmaceuticals, Inc.

Completed

Safety and Efficacy of KPI-121 in Subjects With Postsurgical Inflammation (Hawaii-1)

Ocular Infections, Irritations and Inflammations

United States
a2 Milk Company Ltd.

Completed

A1 Versus A2® Milk on the Gastrointestinal Physiology, Symptoms and Cognitive Behaviour for the Preschool Children

Gut Inflammation
Kissei Pharmaceutical Co., Ltd.

Completed

A Long-term Study of PA21 in Hemodialysis Patients With Hyperphosphatemia

Hemodialysis Patients With Hyperphosphatemia

Japan
UBP Greater China (Shanghai) Co., Ltd

Not yet recruiting

Evaluating Safety and Efficacy of Repeat Doses of UB-621in Adult Patients With Recurrent Genital Herpes

Recurrent Genital Herpes
University Hospital, Strasbourg, France

Unknown

Visual Exploration and Attention: Studies in Patients With Schizophrenia and Autism Spectrum Disorders

Schizophrenia | Autism Spectrum Disorders

France
University of Oxford

Completed

VAC 072-An Efficacy Study of R21/MM in Different Dose Schedules

Malaria

United Kingdom
Ajax Therapeutics, Inc.

Not yet recruiting

A Phase 1 Study of AJ1-11095 in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)

Primary Myelofibrosis | Post-Polycythemia Vera Myelofibrosis | PMF | Post-Essential Thrombocythemia Myelofibrosis | PPV-MF | PET-MF

United States
IDP Discovery Pharma S.L.

Recruiting

A Phase 1/2 Study of IDP-121 in Patients With Relapsed/Refractory Hematologic Malignancies (CASSANDRA)

Chronic Lymphocytic Leukemia (CLL) | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Multiple Myeloma (MM) | High Grade B-Cell Lymphoma, Not Otherwise Specified | Double Hit Lymphoma | Triple Hit Lymphoma

Spain

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