Search clinical trials for: Cyclosporin A

Total 11091 results

National Cancer Institute (NCI)

Active, not recruiting

Selumetinib and Cyclosporine in Treating Patients With Advanced Solid Tumors or Advanced or Metastatic Colorectal Cancer

Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Recurrent Colorectal Carcinoma | Stage IIIA Colorectal Cancer AJCC v7 | Stage IIIB Colorectal Cancer AJCC v7 | Stage IIIC Colorectal Cancer AJCC v7 | Solid Neoplasm

United States, Canada
Seoul National University Hospital

Completed

Comparison Study of Psoriasis Severity Assessment Tools

Psoriasis

Korea, Republic of
The Cleveland Clinic

Completed

Anti-thymocyte Globulin and Cyclosporine as First-Line Therapy in Treating Patients With Severe Aplastic Anemia

Aplastic Anemia

United States
National Cancer Institute (NCI)

Terminated

Dasatinib and Cyclosporine in Treating Patients With Chronic Myelogenous Leukemia Refractory or Intolerant to Imatinib Mesylate

Accelerated Phase Chronic Myelogenous Leukemia | Chronic Phase Chronic Myelogenous Leukemia | Relapsing Chronic Myelogenous Leukemia | Chronic Myelogenous Leukemia, BCR-ABL1 Positive

United States
Shandong University
National Natural Science Foundation of China

Unknown

Safety and Efficacy Study of Umbilical Cord/Placenta-Derived Mesenchymal Stem Cells to Treat Severe Aplastic Anemia

Aplastic Anemia

China
Instituto de Investigación Hospital Universitario...

Recruiting

Optimization of Cyclosporin in Atopic Dermatitis Through Multiomic Predictive Models of Treatment Response (DermAtOmics)

Atopic Dermatitis

Spain
Safaa AA Khaled
Assiut University

Completed

Combination of Thrombopoietin Mimetic and Immunosuppressive Therapy in Aplastic Anaemia

Aplastic Anemia

Egypt
Stanford University

Completed

Ph II of Non-myeloablative Allogeneic Transplantation Using TLI & ATG In Patients w/ Cutaneous T Cell Lymphoma

Lymphoma, Non-Hodgkin | Mycoses | Lymphoma, T-Cell, Cutaneous | Sezary Syndrome | Cutaneous T-cell Lymphoma | Bone Marrow Transplant Failure

United States
Rennes University Hospital
Novartis

Terminated

Switch From Tacrolimus to Cyclosporin in the Treatment of Recurrent Hepatitis C After Liver Transplantation

Chronic Hepatitis C | Evidence of Liver Transplantation

France
Hospices Civils de Lyon

Completed

Cyclosporine and Prognosis in Acute Myocardial Infarction (MI) Patients (CIRCUS)

ST Elevation Acute Myocardial Infarction

France, Spain, Belgium
London School of Hygiene and Tropical Medicine
Armauer Hansen Research Institute, Ethiopia; Alert Hospital, Ethiopia; Homes...

Completed

Ciclosporin in the Management of New Erythema Nodosum Leprosum

Leprosy

Ethiopia
Institute of Hematology & Blood Diseases Hospital

Unknown

Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Classic Paroxysmal Nocturnal Hemoglobinuria (PNH-2012)

Urination Disorders | Thrombosis | Proteinuria | Anemia, Hemolytic | Hemoglobinuria, Paroxysmal | Hemoglobinuria | Paroxysmal Nocturnal Hemoglobinuria | Bone Marrow Failure | Aplastic Anemia,

China
Mahidol University

Completed

Efficacy of 0.05% Cyclosporin Eye Drop in Stevens Johnson Syndrome Patient With Chronic Dry Eye

Stevens-Johnson Syndrome

Thailand
Novaliq GmbH

Completed

CyclASol for the Treatment of Moderate to Severe Dry-eye Disease (DED)

Dry Eye Syndromes

United States
Aurinia Pharmaceuticals Inc.

Completed

Randomized, Placebo and Ciclosporin Controlled Study of ISA247 in Plaque Psoriasis Patients (ESSENCE)

Psoriasis

Canada, Germany, Poland
Institute of Hematology & Blood Diseases Hospital

Unknown

Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Subclinical Paroxysmal Nocturnal Hemoglobinuria and PNH in the Setting of Another Bone Marrow Failure Syndromes(PNH-2013)

Urination Disorders | Thrombosis | Proteinuria | Anemia, Hemolytic | Hemoglobinuria, Paroxysmal | Hemoglobinuria | Paroxysmal Nocturnal Hemoglobinuria | Bone Marrow Failure | Aplastic Anemia,

China
National Eye Institute (NEI)

Completed

Treatment of Dry Eye Syndrome With Cyclosporin A Eye Drops

Keratoconjunctivitis Sicca | Sjogren's Syndrome

United States
Virginia G. Kaklamani

Not yet recruiting

Breast/Cyclosporin A/TNBC (Triple Negative Breast Cancer)

Triple Negative Breast Cancer | DNA Damage Repair Deficiency

United States
National Eye Institute (NEI)

Completed

Cyclosporin Implant to Treat Uveitis

Inflammation | Uveitis | Eye Disease

United States
Instituto de Seguridad y Servicios Sociales de...

Unknown

Cyclosporine A Plus Low-steroid Treatment in COVID-19 Pneumonia

COVID 19 Pneumonia

Mexico
Allergan

Completed

Study of Two Formulations of Cyclosporine Ophthalmic Emulsion in Healthy Volunteers and in Patients With Dry Eye

Dry Eye Syndromes

United States
Medical University of South Carolina

Completed

Evaluation of Blink Tears and Systane Concomitant With Restasis for the Treatment of Dry Eye Symptoms

Dry Eye Syndrome

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Low-Dose Total Body Irradiation and Donor Peripheral Blood Stem Cell Transplant Followed by Donor Lymphocyte Infusion in Treating Patients With Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, or Multiple Myeloma

Stage II Multiple Myeloma | Stage III Multiple Myeloma | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma and other conditions

United States, Germany, Italy
Shandong University

Withdrawn

A Multicenter Investigation of Recombinant Human Thrombopoietin (rhTPO) Combining Cyclosporin A Versus Cyclosporin A in Management of Steroid-Resistant/Relapsed Immune Thrombocytopenia （ITP）

Immune Thrombocytopenia

China
London School of Hygiene and Tropical Medicine
Armauer Hansen Research Institute, Ethiopia; Alert Hospital, Ethiopia; Homes...

Completed

Ciclosporin in the Management of Chronic or Recurrent Erythema Nodosum Leprosum

Leprosy

Ethiopia
Hospices Civils de Lyon

Unknown

Ciclosporin A and Acute Myocardial Infarction

Myocardial Infarction

France
Zambon SpA

Enrolling by invitation

Extension Trial on Efficacy / Safety of L-CsA + SoC in Treating BOS in Post Single or Double Lung Transplant (BOSTON-3) (BOSTON-3)

Bronchiolitis Obliterans | Bronchiolitis Obliterans Syndrome | Obliterative Bronchiolitis

France, United States, Spain, Israel, Belgium, Denmark, Germany, United Kingdom, Austria
Hannover Medical School
Hoffmann-La Roche

Completed

Exchange of Azathioprine by Mycophenolatmofetile and Cyclosporine A Dose Reduction After Heart Transplantation

Heart Transplantation

Germany
University of Minnesota

Withdrawn

Kidney Allograft Dysfunction Without Reversible Causes (KADWORC)

Kidney Graft Dysfunction

United States
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Safety and Effectiveness of Trappa Ethanolamine Tablets Combined With Ciclosporin in the Treatment of Primary Treatment of Non-severe Aplastic Anemia

Non-severe Aplastic Anemia

China
Maruho Europe Limited

Completed

Drug-Drug Interaction Study: ASP2151 and Ciclosporin

Healthy

United Kingdom
Bing Han

Completed

Sirolimus Treatment for Newly Diagnosed Primary Acquired PRCA (PRCA)

Pure Red Cell Aplasia, Acquired

China
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Cyclosporine, Pravastatin Sodium, Etoposide, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute... and other conditions

United States
LEO Pharma

Withdrawn

Investigation of Flare and Remission in Subjects With Atopic Dermatitis

Atopic Dermatitis

Netherlands
St. Franziskus Hospital

Completed

Cyclosporine A in the Treatment of Juvenile Idiopathic Arthritis (JIA) Associated Chronic Anterior Uveitis

Uveitis | Juvenile Idiopathic Arthritis

Germany
Sirion Therapeutics, Inc.

Completed

Study of Cyclosporine in the Treatment of Dry Eye Syndrome (ST-603-006)

Dry Eye Syndromes

United States
National Cancer Institute (NCI)

Completed

Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer

HIV Infection | Unspecified Childhood Solid Tumor, Protocol Specific | Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal... and other conditions

United States
Hospices Civils de Lyon

Withdrawn

Postconditioning by Cyclosporin A in Pulmonary Transplantation (CsA Poumon)

Lung Transplantation

France
Rockefeller University

Completed

Reversal of Epidermal Phenotype in Severe Atopic Dermatitis With Cyclosporine Therapy

Eczema | Atopic Dermatitis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cyclosporine A to Treat Hypertrophic Cardiomyopathy (HCM)

Cardiomyopathy, Hypertrophic | Heart Hypertrophy

United States
University of Oslo School of Pharmacy

Completed

Metabolic Pattern of Cyclosporine A and Acute Renal Failure

Heart Transplantation | Acute Renal Failure

Norway
University of Oslo School of Pharmacy

Completed

Intracellular and Renal/Myocardial Tissue Concentrations of Cyclosporine A (CsA) and Rejection Frequency Following Transplantation

Heart Transplantation | Renal Transplantation

Norway
University Medical Center Groningen
ZonMw: The Netherlands Organisation for Health Research and Development

Unknown

Alitretinoin vs Cyclosporine in Severe Recurrent Vesicular Hand Eczema (ALICsA)

Hand Eczema

Netherlands
Fudan University

Unknown

Use of Cyclosporin A for the Treatment of Recurrent Miscarriage

Miscarriage, Recurrent

China
PerioC Limited

Completed

The Effect of Locally Delivered Ciclosporin as an Adjunct to Healing After Treatment of Periodontal Pockets

Periodontitis

Sweden
Novartis Pharmaceuticals

Completed

Long-term Study of Ciclosporin for Atopic Dermatitis

Severe Atopic Dermatitis
Ameera Gamal Abdelhameed
Ministry of Health, Kuwait

Unknown

Topical Steroids and Cyclosporin-A for COVID-19 Keratoconjunctivitis

Keratonjunctivitis

Kuwait
Institute of Hematology & Blood Diseases Hospital...
Jiangsu Hengrui Pharmaceuticals Co.,Ltd

Recruiting

Herombopag Added to Cyclosporine in Non Severe Aplastic Anemia

Non Severe Aplastic Anemia | Untreated

China
University Hospital, Clermont-Ferrand
University Hospital, Montpellier; Poitiers University Hospital; Centre Hospitalier... and other collaborators

Unknown

Cyclosporine A Pretreatment and Kidney Graft Function (Cys-A-Rein)

Kidney Transplantation | Brain Death

France

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