Search clinical trials for: Donor lymphocytes

Total 1645 results

St. Petersburg State Pavlov Medical University

Active, not recruiting

Risk-adapted Donor Lymphocyte Infusion After Allo-HSCT in Children With Hematologic Malignancy

Hematologic Malignancy

Russian Federation
Roswell Park Cancer Institute

Completed

Donor Lymphocyte Infusion in Treating Patients With Recurrent or Persistent Hematologic Cancer After Donor Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm

United States
Assistance Publique - Hôpitaux de Paris
Pierre and Marie Curie University; Paris 12 Val de Marne University

Completed

Suicide Gene Therapy for Donor Lymphocytes Infusion After Allogeneic Hematopoietic Stem Cell Transplantation (ILD-TK01)

Hematological Malignancy

France
Beijing Friendship Hospital

Recruiting

Clinical Study of Donor EBV-CTL Infusion in Patients With CAEBV and EBV-HLH After Allo-HSCT

Chronic Active Epstein-Barr Virus Infection | Virus-Associated Hemophagocytic Syndrome

China
University of Erlangen-Nürnberg Medical School
German Research Foundation; University Hospital, Essen; Wuerzburg University... and other collaborators

Unknown

Open-label Clinical Trial to Investigate the Safety and Tolerability of Allogeneic B-cell Concentrates for Immune Reconstitution After Allogeneic Stem Cell Transplantation Measured as Response to a Antedated Single Vaccination (B-cell therapy)

Acute Myeloid Leukemia | Multiple Myeloma | Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia | Myelodysplastic Syndrome | Aplastic Anemia | Non Hodgkin's Lymphoma | Hodgkin's Disease

Germany
Dana-Farber Cancer Institute
National Cancer Institute (NCI); Beth Israel Deaconess Medical Center; Brigham...

Completed

Donor Dendritic Cells And Donor Lymphocytes in Patients With Relapsed Hematologic Malignancies After Allogeneic Transplant

Hematologic Malignancy

United States
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Guangzhou First People's Hospital; Sun Yat-Sen... and other collaborators

Completed

MRD-directed Donor Lymphocyte Infusion for Reduce of Relapse After Allo-HSCT

Hematopoietic Stem Cell Transplantation | Minimal Residual Disease | Relapse | Donor Lymphocyte Infusion

China
Masonic Cancer Center, University of Minnesota

Completed

Donor Lymphocyte Infusion (DLI) for Relapsed (Post Transplant) Leukemia

AML | MDS | Leukemia, Lymphocytic, Acute | Leukemia, Myeloid, Chronic

United States
Peking University People's Hospital

Unknown

Chemotherapy and DLI for Prevention of Second Relapse in Patients With Relapsed Acute Leukemia After Allotransplant

Acute Leukemia | Allogeneic Hematopoietic Stem Cell Transplantation | Minimal Residual Disease | Relapse | Donor Lymphocyte Infusion | Graft-versus-host Disease

China
M.D. Anderson Cancer Center
Eligix

Terminated

CD8 DLI for Patients With Relapse or Residual Disease Following Allogeneic Stem Cell Transplantation

Multiple Myeloma | Chronic Lymphocytic Leukemia | Chronic Myelogenous Leukemia | Non Hodgkin's Lymphoma | Hodgkin's Disease

United States
Great Ormond Street Hospital for Children NHS Foundation...

Terminated

Suicide Gene Therapy Trial

Haploidentical Stem Cell Transplantation

United Kingdom
Hong Kong Children's Hospital

Recruiting

CD62L Depleted Donor Lymphocyte Infusion With T Cell Depleted Haploidentical Hematopoietic Stem Cell Transplantation

Hematopoietic Organs; Disorder

Hong Kong
Institut Paoli-Calmettes

Not yet recruiting

Early Prophylactic Donor Lymphocyte Infusion After Allo-HSCT for Patients With AML (ELIT-AML01)

Acute Myeloid Leukemia

France
Everett Meyer
National Cancer Institute (NCI)

Withdrawn

Donor Regulatory T Cells in Treating Patients With Visceral Acute Graft-versus-Host Disease After Stem Cell Transplant

Graft Versus Host Disease

United States
Rigshospitalet, Denmark

Recruiting

Innate Donor Effector Allogeneic Lymphocyte Infusion After Stem Cell Transplantation: the IDEAL Trial (IDEAL)

AML/MDS

Denmark
Washington University School of Medicine
National Cancer Institute (NCI); MacroGenics

Recruiting

Flotetuzumab for Relapsed Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Following Allogeneic Hematopoietic Cell Transplantation (Allo-HCT)

Relapsed Acute Myeloid Leukemia

United States
University Hospital Tuebingen

Recruiting

CD45RA Depleted DLI After TCRα/β Depleted Haploidentical HCT (CD45RADLIHaplo)

Hematologic Malignancy

Germany
DERSHENG SUN

Unknown

Lymphocytes Subpopulation in Cancer Patients (CaLym)

Cancer

Korea, Republic of
University of California, San Francisco
Johns Hopkins All Children's Hospital

Completed

A Study of Withdrawal of Immunosuppression and Donor Lymphocyte Infusions Following Allogeneic Transplant for Pediatric Hematologic Malignancies

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Acute Leukemia | Chronic Myelogenous Leukemia | Biphenotypic Leukemia | Pre-leukemic Syndromes | Monosomy 7 | Bone Marrow Clonal Malformations

United States
National University Hospital, Singapore
Singapore General Hospital

Unknown

T-cell Depleted Donor Lymphocyte Infusion (DLI)for Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome (MDS)

Acute Myeloid Leukemia | Myelodysplastic Syndromes

Singapore
Assistance Publique - Hôpitaux de Paris
Pierre and Marie Curie University; Université Paris XII

Completed

Amplifying Graft-Versus-Tumor Effect by Donor Regulatory T-Cell Depletion Before Donor Lymphocytes Infusion (ILD-Treg)

Hematologic Neoplasms | Relapse

France
National Cancer Institute (NCI)

Terminated

Pilot Study of Radiation-Enhanced Allogeneic Cell Therapy for Progressive Hematologic Malignancy After Allogeneic Hematopoietic Stem Cell Transplantation

Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Chronic Lymphocytic Leukemias | Multiple Myeloma With Plasmacytoma

United States
New York Medical College
Johns Hopkins University; M.D. Anderson Cancer Center; Baylor College of Medicine and other collaborators

Terminated

Allogeneic Stem Cell Transplantation With Adoptive Immunotherapy in Epstein-Barr Virus Positive Recurrent/Refractory Hodgkins Lymphoma

Hodgkins Lymphoma

United States
Nelson Chao

Terminated

Trial of CMV Specific DLIs From 3-6/6 HLA Matched Family Member Following Nonmyeloablative Allo SCT

Cytomegalovirus Infections

United States
Baptist Health South Florida

Active, not recruiting

T-cell Receptor α/β Depleted Donor Lymphocyte Infusion

Myeloid Malignancy | Lymphoid Leukemia, Acute | Plasma Cell Tumor

United States
Washington University School of Medicine

Completed

Infusion of Genetically Modified T Cell for Post Transplant Patients With Relapsed Disease

Lymphoma, Non-Hodgkin | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma | Hodgkin Disease

United States
Kiadis Pharma

Terminated

Efficacy and Safety of a Donor Lymphocyte Preparation Depleted of Functional Host Alloreactive T-cells (ATIR) in Patients Undergoing a Peripheral Blood Stem Cell Transplant From a Related, Haploidentical Donor

Lymphoma | Myeloid Leukemia | Myeloproliferative Disorders | Multiple Myeloma | Myelodysplastic Syndrome | Lymphoblastic Leukemia

Canada, Netherlands, Germany, Belgium, United States, Italy, United Kingdom
Mitchell Horwitz, MD

Completed

Naive T-Cell Depleted DLI Following Allo Stem Cell Transplant

Hematological Malignancies

United States
Suping ZHANG

Recruiting

Blinatumomab for Relapsed Acute B Lymphoblastic Leukemia After Transplantation

Acute B-cell Lymphoblastic Leukemia

China
Seoul National University Hospital

Terminated

Irradiated Donor Lymphocyte Infusion Plus High-dose IL-2

Metastatic Malignant Melanoma and Renal Cell Carcinoma

Korea, Republic of
Istituto Clinico Humanitas

Completed

Feasibility and Efficacy of Modified Donor Lymphocytes Infusion (CD45RA Negative Selected) After Haploidentical Transplantation With Post-transplantation Cyclophosphamide in Patients With Hematological Malignancies (ONC-2016-002).

Infection | Graft Vs Host Disease | Hematological Malignancy | Bone Marrow Transplant Complications | Bone Marrow Transplant Infection

Italy
University of Wisconsin, Madison

Recruiting

BK With VST for Kidney Transplant Patients

BK Virus Infection | Kidney Transplant Infection

United States
Kiadis Pharma

Completed

Dose-ranging Study of a Single Administration of T-cell Add-back Depleted of Host Alloreactive Cells in Patients Undergoing a Peripheral Blood Stem Cell Transplant From a Related, Haploidentical Donor

Hematologic Diseases | Hematologic Malignancies

Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Immunex Corporation

Withdrawn

Therapy of Relapsed AML With Chemotherapy and Dendritic Cell Activated Lymphocytes

Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia
Wake Forest University Health Sciences

Terminated

Donor Lymphocyte Infusion After Alternative Donor Transplantation

Immunodeficiency

United States
Sumithira Vasu

Completed

Daratumumab and Donor Lymphocyte Infusion in Treating Participants With Relapsed Acute Myeloid Leukemia After Stem Cell Transplant

Recurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes | Recurrent Adult Acute Myeloid Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Minimal Residual Disease

United States
M.D. Anderson Cancer Center
Ziopharm Oncology

Completed

Infusion of Allogeneic CD19-Specific T Cells From Peripheral Blood

Lymphoma | Leukemia

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

Enhancing Graft vs Leukemia Via Delayed Ex-Vivo Co-Stimulated DLI After Non-Myeloablative Stem Cell Transplantation

Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia

United States
Haukeland University Hospital

Completed

Effects and Interactions of Liquorice and Grapefruit on Glucocorticoid Replacement Therapy in Addison's Disease

Addison Disease

Norway
H. Lee Moffitt Cancer Center and Research Institute

Active, not recruiting

CD8 Depleted, Non-engrafting, HLA Mismatched Unrelated Infusion With MDS and Secondary AML

Myelodysplastic Syndromes | Secondary Acute Myeloid Leukemia

United States
Karolinska University Hospital
Nordic MDS Group

Recruiting

A Study Using Subject-specific MRD to Adopt Treatment After HSCT for Subjects With MDS

Myelodysplastic Syndromes | Acute Myeloid Leukemia With Myelodysplasia Related Disease and < 30% Blasts | Mixed Myelodysplastic/Myeloproliferative Disease

Sweden
The First Affiliated Hospital of Soochow University
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

PD-1 Inhibitor, Azacitidine and Low-dose DLI in AML Relapse After Allo-HSCT

Acute Myeloid Leukemia

China
University Hospital of Limerick

Completed

The Circulating Fibrocyte - a Novel and Accurate Biomarker in Diagnosing Acute Appendicitis in Adults

Appendicitis

Ireland
GlaxoSmithKline

Completed

Expanded Access Study Of BEXXAR® For Low Grade And Transformed Low-Grade Non-Hodgkin's Lymphoma

Lymphoma, Non-Hodgkin
Shanghai General Hospital, Shanghai Jiao Tong University...
Shanghai iCELL Biotechnology Co., Ltd, Shanghai, China

Completed

CMV-CTL for the Treatment of CMV Infection After HSCT

Cytomegalovirus Infections | Hematological Disease

China
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Donor Lymphocyte Infusion in Treating Patients With Persistent, Relapsed, or Progressing Cancer After Donor Hematopoietic Cell Transplant

Recurrent Hodgkin Lymphoma | Recurrent Adult Acute Myeloid Leukemia | Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent Non-Hodgkin Lymphoma | Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Recurrent Plasma Cell Myeloma

United States, Germany, Italy
Laura Kair
The Gerber Foundation; Children's Miracle Network

Completed

Rx Milk Study of Donor Milk Supplementation to Improve Breastfeeding Outcomes (Rx Milk)

Exclusive Breastfeeding | Breastfeeding Duration | Donor Milk Supplementation

United States
Monica Thakar

Completed

Phase 2 STIR Trial: Haploidentical Transplant and Donor Natural Killer Cells for Solid Tumors (STIR)

Osteosarcoma | Ewing Sarcoma | Neuroblastoma | Rhabdomyosarcoma | CNS Tumors

United States
Masonic Cancer Center, University of Minnesota
Incyte Corporation

Completed

Multi-Ctr PII Cmb.Modality Tx Ruxolitinib, Decitabine, and DLI for Post HSCT in AML/MDS

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Myeloid and Monocytic Leukemia

United States
Groupe Francophone des Myelodysplasies
Astex Pharmaceuticals, Inc.

Active, not recruiting

ASTX727 and Donor Lymphocyte Infusions After Allogenic Stem Cell Transplantation in Very High Risk MDS or AML Patients

AML | MDS

France

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