Search clinical trials for: Donor blood stem cells and T cells

Total 8547 results

Beijing GoBroad Hospital

Not yet recruiting

CD5 Chimeric Antigen Receptor (CAR) T Cells in Subjects With Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia, in Relapse | Refractory Acute Lymphoblastic Leukemia | T-Cell Acute Lymphocytic Leukemia
Laura Johnston
National Institutes of Health (NIH)

Completed

Phase 1 Infused Donor T Regulatory Cells in Steroid Dependent/Refractory Chronic GVHD

Graft Versus Host Disease | Allogeneic Hematopoietic Cell Transplant Recipient

United States
Mitchell Horwitz, MD

Completed

Naive T-Cell Depleted DLI Following Allo Stem Cell Transplant

Hematological Malignancies

United States
Masonic Cancer Center, University of Minnesota

Terminated

Donor T Cells in Treating Patients With High-Risk Hematologic Cancer Undergoing Donor Peripheral Blood Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm | Graft Versus Host Disease

United States
Samuel Strober
California Institute for Regenerative Medicine (CIRM)

Recruiting

Inducing Graft Tolerance in HLA Haplotype Matched Related and 3 Ag Matched Unrelated Living Donor Kidney Transplantation (CIRM)

Immune Tolerance

United States
Wuhan Sian Medical Technology Co., Ltd
Wuhan Union Hospital, China; Xiangyang Central Hospital; Jingzhou Central Hospital and other collaborators

Unknown

Anti-CD19 CAR-T Therapy Combine With HSCT to Treat MRD+ B-cell Malignancies

B Cell Lymphoma | Acute Lymphoblastic Leukemia

China
University College, London

Unknown

Autologous Stem Cells in Achilles Tendinopathy (ASCAT)

Tendinopathy | Achilles Tendinitis | Achilles Degeneration | Achilles Tendinitis, Right Leg | Achilles Tendon Thickening | Achilles Tendinitis, Left Leg

United Kingdom
Zhejiang University
Yake Biotechnology Ltd.

Recruiting

CD7 CAR-T Bridging to alloHSCT for R/R CD7+Malignant Hematologic Diseases

Neoplasms | Hematologic Diseases

China
Children's Hospital of Philadelphia

Completed

CHP 834 Unrelated and Partially Matched Related Donor Peripheral Stem Cell Transportation for T and B Cell Depletion (CliniMACs)

Immunodeficiencies

United States
Porteus, Matthew, MD
California Institute for Regenerative Medicine (CIRM)

Recruiting

Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Adults With T-allo10 Cells Addback

Hematologic Diseases

United States
Zhejiang University
Yake Biotechnology Ltd.

Recruiting

Autologous Hematopoietic Stem Cell Transplantation Combined With CAR-T Cells in the Treatment of Refractory and Relapsed Malignant Lymphoma

Lymphoma

China
Beijing GoBroad Hospital

Recruiting

Clinical Trial of CD19 and CD22 CAR Sequential Therapy Versus Single CD19 CAR Bridging to HSCT for r/r B-ALL Patients

Acute Lymphoblastic Leukemia, in Relapse | B-cell Acute Lymphoblastic Leukemia | Refractory Acute Lymphoid Leukemia

China
Christopher Dvorak

No longer available

Expanded Access Protocol (EAP) Using the CliniMACS® Device for Pediatric Haplocompatible Donor Stem Cell Transplant

Acute Myeloid Leukemia | Leukocyte Disorders | Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia | Myelodysplastic Syndrome | Cytopenias | Immune Deficiency | Lymphomas | Bone Marrow Failure | Osteopetrosis | Hemoglobinopathy | Anemia Due to Intrinsic Red Cell Abnormality

United States
Johann Wolfgang Goethe University Hospital

Completed

Safety and Feasibility Study of Autologous Bone Marrow Cell Transplantation in Patients With Peripheral Arterial Occlusive Disease (PAOD)

Arterial Occlusive Diseases

Germany
National Cancer Institute (NCI)

Completed

Administration of Anti-CD19-chimeric-antigen-receptor-transduced T Cells From the Original Transplant Donor to Patients With Recurrent or Persistent B-cell Malignancies After Allogeneic Stem Cell Transplantation

Lymphoma, B-Cell | Leukemia, B-cell | Lymphoma, Hodgkins | Lymphoma, Non-hodgkins

United States
Joseph C. Wu
California Institute for Regenerative Medicine (CIRM)

Recruiting

Human Embryonic Stem Cell-Derived Cardiomyocyte Therapy for Chronic Ischemic Left Ventricular Dysfunction (HECTOR)

Chronic Ischemic Left Ventricular Dysfunction

United States
Aryn Knight
The University of Texas Health Science Center, Houston; Baylor College of Medicine and other collaborators

Withdrawn

Umbilical Cord Blood in the Treatment of Stroke in Children. (Pedi Stroke)

Arterial Ischemic Stroke (AIS) in Children

United States
Chinese PLA General Hospital

Unknown

A Feasibility and Safety Study of Concomitant Therapy With Allo-CAR-T Cells and Allo-HSCT in Patients With Relapse or Refractory Leukemia

B Cell Leukemia

China
University Hospitals Cleveland Medical Center
Case Western Reserve University

Recruiting

Impact of Mesenchymal Stem Cells in Knee Osteoarthritis

Musculoskeletal Pain | Knee Osteoarthritis | Cartilage Injury | Cartilage Degeneration

United States
University of Liege

Completed

Mesenchymal Stem Cell Infusion as Prevention for Graft Rejection and Graft-versus-host Disease

Hematological Malignancies

Belgium
Hospital Universitario Dr. Jose E. Gonzalez

Unknown

Autologous Bone Marrow Stem Cells for Children With Autism Spectrum Disorders (Autism)

Autism | Autism Spectrum

Mexico
Memorial Sloan Kettering Cancer Center

Terminated

T-cell Depleted Hematopoietic Stem Cell Boosts Without Conditioning for Poor Marrow Graft Function Following Allogeneic Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplant | Poor Marrow Graft Function

United States
UPECLIN HC FM Botucatu Unesp
Laboratório de Genética Humana e Terapia Celular, Unesp - Assis; Instituto...

Completed

Safety Study of Cell Therapy to Treat Chronic Obstructive Pulmonary Disease (COPD-01)

Chronic Obstructive Pulmonary Disease | Pulmonary Emphysema

Brazil
University College, London
Medical Research Council

Completed

Infusion of Depleted T Cells Following Unrelated Donor Stem Cell Transplant (ICAT) (ICAT)

Haematological Malignancies

United Kingdom
University Hospital Carl Gustav Carus

Completed

Prophylactic Transfer of Leukemia-reactive T Cells After Allogeneic Transplantation

Chronic Myeloid Leukemia

Germany
Peking University People's Hospital

Completed

Preemptive Therapy With CMV-specific T Cells Infusion to Prevent Refractory CMV Infection Post Transplantation

CMV Infection

China
Postgraduate Institute of Medical Education and...

Completed

Efficacy Of Autologous Bone Marrow Derived Stem Cell Transplantation In Patients With Type 2 Diabetes Mellitus (SCT)

Type 2 Diabetes Mellitus

India
James Baumgartner, MD
CBR Systems, Inc.

Completed

Safety of Autologous Stem Cell Infusion for Children With Acquired Hearing Loss

Sensorineural Hearing Loss

United States
JKastrup
European Union

Completed

Stem Cell Therapy in IschEmic Non-treatable Cardiac Disease (SCIENCE)

Heart Failure

Denmark
Seattle Children's Hospital

Active, not recruiting

Pilot Study of T-APCs Following CAR T Cell Immunotherapy for CD19+ Leukemia

CD 19+ Acute Leukemia

United States
Everett Meyer
National Cancer Institute (NCI)

Withdrawn

Donor Regulatory T Cells in Treating Patients With Visceral Acute Graft-versus-Host Disease After Stem Cell Transplant

Graft Versus Host Disease

United States
University College, London
Deutsche Krebshilfe e.V., Bonn (Germany); European Union; The Leukemia and Lymphoma... and other collaborators

Terminated

CD19-CAR Immunotherapy for Childhood Acute Lymphoblastic Leukemia (ALL) (CD19TPALL)

Acute Lymphoblastic Leukemia

United Kingdom, Germany
St. Jude Children's Research Hospital

Completed

Haploidentical Stem Cell Transplant for Treatment Refractory Hematological Malignancies

Lymphoma, Non-Hodgkin | Hodgkin Disease | Chronic Myeloid Leukemia | Acute Myeloid Leukemia (AML) | Acute Lymphoblastic Leukemia (ALL) | Paroxysmal Nocturnal Hemoglobinuria (PNH) | Myelodysplastic Syndrome (MDS) | Secondary AML | Juvenile Myelomonocytic Leukemia (JMML) | Secondary MDS

United States
Nantes University Hospital

Not yet recruiting

Study on the Treatment of Anal Fistulas Using Alofisel Versus Fat Autologous Stem Cells (CHAZAM)

Crohn Disease | Anal Fistula
Hospital Sao Rafael
Oswaldo Cruz Foundation; Hospital Espanhol; Irep Sociedade de Ensino Superior...

Completed

Autologous Bone Marrow Stem Cell Transplantation in Patients With Spinal Cord Injury

Spinal Cord Injury

Brazil
Instituto do Cerebro de Brasilia
Hospital Sao Lucas da PUCRS; Instituto do Cerebro da PUCRS

Completed

Autologous Bone Marrow Stem Cells Transplantation in Patients With Temporal Lobe Epilepsy

Epilepsy

Brazil
University College, London

Suspended

Study of Adoptive Immunotherapy With Donor-derived CMV-specific T Cells for Recipients of Allo-HSCT (CMV_TCR-001)

CMV Infection | Haematological Malignancies

United Kingdom
Assistance Publique - Hôpitaux de Paris
Pierre and Marie Curie University; Université Paris XII

Completed

Amplifying Graft-Versus-Tumor Effect by Donor Regulatory T-Cell Depletion Before Donor Lymphocytes Infusion (ILD-Treg)

Hematologic Neoplasms | Relapse

France
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Sun Yat-sen University; Guangzhou First... and other collaborators

Unknown

Mesenchymal Stem Cells Combined With Cord Blood for Treatment of Graft Failure

Mesenchymal Stem Cells | Hematopoietic Stem Cell Transplantation | Hematological Diseases | Graft Failure | Umbilical Cord Blood

China
Chaitanya Hospital, Pune

Unknown

Study the Safety and Efficacy of Bone Marrow Derived Autologous Cells for the Treatment of Optic Nerve Disease (OND)

Optic Atrophy

India
Throne Biotechnologies Inc.

Not yet recruiting

Stem Cell Educator Therapy Treat the Viral Inflammation in COVID-19

Severe Acute Respiratory Syndrome (SARS) Pneumonia
Beijing GoBroad Hospital

Recruiting

Autologous and Donor-derived CD7 CAR-T Therapy in Refractory or Relapsed T-cell Acute Lymphoblastic Leukemia/Lymphoma

Acute Lymphoblastic Leukemia, in Relapse | Refractory Acute Lymphoblastic Leukemia | T-cell Acute Lymphoblastic Leukemia

China
Leiden University Medical Center

Completed

Mesenchymal Stem Cells and Subclinical Rejection (Measure)

Organ Transplantation

Netherlands
Postgraduate Institute of Medical Education and...
Indian Council of Medical Research

Unknown

Tissue Distribution of F18-FDG Labelled Autologous Bone Marrow Derived Stem Cells in Patients With Type 2 DM

Type 2 Diabetes Mellitus

India
Fuda Cancer Hospital, Guangzhou
Jinan University Guangzhou

Completed

Safety and Efficiency of γδ T Cell Against Non Small Lung Cancer ( Without EGFR Mutation)

Lung Cancer

China
St. Jude Children's Research Hospital

Completed

Partially Matched Stem Cell Transplantation for Patients With Refractory Severe Aplastic Anemia or Refractory Cytopenias

Anemia, Aplastic | Diamond-Blackfan Anemia | Amegakaryocytic Thrombocytopenia | Kostmann Syndrome

United States
Acibadem University

Unknown

Efficacy of Umbilical Cord Mesenchymal Stem Cells in Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy

Turkey
Burnasyan Federal Medical Biophysical Center

Unknown

Effectiveness and Safety of MMSCs for Enhancing Hematopoietic Recovery and Prophylaxis of Neutropenic Enterocolitis

Neutropenic Enterocolitis | Myeloablative Chemotherapy Induced Bone Marrow Aplasia

Russian Federation
Ageless Regenerative Institute
Instituto de Medicina Regenerativa

Withdrawn

Adipose Derived Stem Cell Therapy for Autism

Autism

United States
Mariella Enoc

Completed

Trial to Assess the Efficacy of a TCR Alfa Beta Depleted Graft in Pediatric Affected by ALL or AML and Receiving an HSCT

Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia | Non-Hodgkin Lymphoma | Leukemia Acute Myeloid - AML

Italy

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