Search clinical trials for: EDIT-301

Total 4053 results

Editas Medicine, Inc.

Recruiting

EDIT-301 for Autologous Hematopoietic Stem Cell Transplant (HSCT) in Participants With Transfusion-Dependent Beta Thalassemia (TDT)

Hemoglobinopathies | Thalassemia Major | Thalassemia Intermedia | Transfusion Dependent Beta Thalassemia

United States, Canada
Editas Medicine, Inc.

Active, not recruiting

Single Ascending Dose Study in Participants With LCA10

Retinal Degeneration | Eye Diseases, Hereditary | Vision Disorders | Leber Congenital Amaurosis 10 | Inherited Retinal Dystrophies | Retinal Disease | Eye Disorders Congenital

United States
Editas Medicine, Inc.

Recruiting

A Study Evaluating the Safety and Efficacy of EDIT-301 in Participants With Severe Sickle Cell Disease (RUBY)

Sickle Cell Disease | Hemoglobinopathies

United States, Canada
Alcediag
Hospital Clinic of Barcelona; Fundacion Clinic per a la Recerca Biomédica; Fundació... and other collaborators

Recruiting

Clinical Validation Study for EDIT-B Test: an Aid for Differential Diagnosis of Bipolar Disorder, Based on RNA Editing Blood Biomarkers (EDIT-B)

Bipolar Disorder | Major Depressive Disorder

Spain, France, Denmark
EGEN, Inc.

Terminated

A Study of the Safety and Biological Activity of Intraperitoneal (IP) EGEN-001 Administered Alone and in Combination With Standard Chemotherapy in Colorectal Peritoneal Carcinomatosis Patients

Colorectal Cancer

United States
NHS Greater Glasgow and Clyde
Rocket Medical plc

Unknown

EDIT Management Feasibility Trial (Pre-EDIT)

Pleural Effusion, Malignant

United Kingdom
Hookipa Biotech GmbH

Recruiting

HB-302/HB-301 Therapy in Participants With Metastatic Castration-Resistant Prostate Cancer

Prostate Cancer Metastatic

United States
NewG Lab Pharma

Active, not recruiting

KAT-101 in Subjects With Hepatocellular Carcinoma (HCC)

Hepatocellular Carcinoma | Fibrolamellar Carcinoma

Korea, Republic of
Swiss Tropical & Public Health Institute
Pevion Biotech Ltd; Mymetics Corporation

Completed

Phase Ib Trial of Two Virosome Formulated Malaria Vaccine Components (PEV 301, PEV 302) in Tanzania (PMAL03)

Falciparum Malaria

Tanzania
Ospedale San Raffaele

Unknown

Mavrilimumab in Severe COVID-19 Pneumonia and Hyper-inflammation (COMBAT-19) (COMBAT-19)

Covid-19 | Acute Respiratory Failure | ARDS, Human | Sars-CoV2 | Viral Pneumonia

Italy
Orion Corporation, Orion Pharma
Bayer

Completed

Mass Balance, Pharmacokinetics, Biotransformation and Bioavailability Study of ODM-201 in Healthy Male Subjects (ARIADME)

Healthy

United Kingdom
Chong Kun Dang Pharmaceutical

Completed

A Clinical Trial to Compare and Evaluate the Safety and Pharmacokinetics of CKD-391(2)

Dyslipidemias

Korea, Republic of
Rutgers, The State University of New Jersey
National Institute on Aging (NIA)

Recruiting

Pilot Testing Dementia-Enhanced Training and Tool for Home Hospice Clinicians (EDITH-HC)

Alzheimer's Disease and Related Dementias

United States
University Hospital, Clermont-Ferrand

Unknown

Cross-cultural Adaptation and Validation of the French Version of the EXIT (EXperiences of Induction Tool) (EXIT) (EXIT)

Induction of Labor

France
Sorrento Therapeutics, Inc.

Withdrawn

A Study of STI-3031 (an Anti-PD-L1 Antibody) in Patients With Selected Relapsed/Refractory Malignancies

Diffuse Large B Cell Lymphoma | Biliary Tract Cancer | Peripheral T Cell Lymphoma | Extranodal NK T Cell Lymphoma, Nasal
Philips Healthcare

Terminated

ZeroFall - Reliability Testing of Optical Sensor to Detect Bed Exit for Patients in Hospital

Delirium of Mixed Origin

United Kingdom
The Catholic University of Korea

Unknown

Efficacy of 311-nm Ti:Sapphire Laser Versus 308-nm Excimer Laser Treatment in Vitiligo

Vitiligo

Korea, Republic of
Flame Biosciences

Withdrawn

Phase 1/2a Study to Evaluate FL-301 in Patients With Advanced Solid Tumors

Gastric Cancer | Solid Tumor | Pancreas Cancer
University of Pittsburgh

Recruiting

Post-Concussion Differences Between Buffalo Concussion Treadmill Test (BCTT) and Modified Dynamic Exertion (mEXiT) Test

Mild Traumatic Brain Injury

United States
Woolcock Institute of Medical Research
University of Sydney

Completed

Cannabinol Use in Patients With Insomnia Disorder (CUPID)

Insomnia Disorder

Australia
The Miriam Hospital

Completed

System Based Tracking and Treatment for Emergency Patients Who Smoke: STTEPS (STTEPS)

Tobacco Dependence

United States
Mohamed Mahmoud Dohiem

Recruiting

Digital VS. Conventional Ear Impression

Patient Loss His Ear and Need Auricular Prosthesis

Egypt
Beth Israel Deaconess Medical Center
National Institute of Neurological Disorders and Stroke (NINDS); Dartmouth-Hitchcock...

Completed

Feasibility of an Electrical Impedance Tomography Device for Pulmonary Function Testing in ALS Patients

ALS

United States
Universitaire Ziekenhuizen KU Leuven
Belgium Health Care Knowledge Centre; Erasmus University Rotterdam

Active, not recruiting

Blended Care Versus Face-to-Face Therapy for Depression (BLENDED)

Major Depressive Disorder

Belgium
BioSerenity

Unknown

Monitoring of Regional Lung Ventilation by Chest Electrical Impedance in the Course of Extubation (EXIT)

Respiratory Disease

France
M.D. Anderson Cancer Center

Withdrawn

A Feasibility and Acceptability Pilot Study Evaluating a Patient-Specific Targeted Intervention Using Patient Navigators or Routine Clinical Care

Breast Cancer

United States
University Hospital, Ghent

Completed

Exclusion of Non-involved Uterus From the Target Volume in Locally Advanced Cervical Cancer (EXIT)

Uterine Cervical Neoplasms

Belgium
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Recruiting

REcruitment MAneuvers and Mechanical Ventilation Guided by EIT in pARDS (REMAV-EIT)

ARDS | Respiratory Disease | Pediatric Respiratory Distress Syndrome

Italy
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Recruiting

Effects of NIV and CPAP on Ventilation Distribution, Measured by EIT, During Deep Sedation in Paediatric Patients (NIVEIT-ped)

Respiratory Failure | Sedation | Mechanical Ventilation Complication

Italy
Sensei Biotherapeutics, Inc.
Accelovance

Completed

Phase 1 Trial of PAN-301-1 (SNS-301) in Cancer Patients

Prostate Cancer

United States
Stefan Kluge

Completed

Electric Impedance Tomography Before and After Dilatative Tracheotomy

ICU Patients | Tracheotomy Required

Germany
First Affiliated Hospital of Zhejiang University

Unknown

Effect of EDIP Based Diet on CD Activity

Crohn Disease
Medtronic Cardiovascular

Completed

Medtronic HAMMOCK Post Approval Study

Heart Valve Diseases

United States, Germany, Poland
University Hospital of Patras

Completed

Choroidal Thickness in Beta-thalassemia Patients

Beta-Thalassemia

Greece
Kiora Pharmaceuticals, Inc.

Recruiting

A Phase I/II Dose-escalating Study of the Safety, Tolerability and Efficacy of KIO-301 Administered Intravitreally to Patients With Retinitis Pigmentosa and Choroideremia (ABACUS) (ABACUS)

Retinitis Pigmentosa | Choroideremia

Australia
LYSOGENE

Completed

Long-term Follow-up of Sanfilippo Type A Patients Treated by Intracerebral SAF-301 Gene Therapy

Mucopolysaccharidosis Type III A | Sanfilippo Disease Type A

France
LYSOGENE

Completed

Intracerebral Gene Therapy for Sanfilippo Type A Syndrome

Mucopolysaccharidosis Type III A | Sanfilippo Disease Type A

France
Lumen Bioscience, Inc.

Recruiting

A Study to Determine the Tolerability of Intranasal LMN-301

COVID-19

Australia
University of Alabama at Birmingham

Recruiting

NTX-301 in MDS/AML

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia

United States
Kodiak Sciences Inc

Terminated

Exploratory Study to Investigate the Bioactivity, Ocular and Systemic Safety, Tolerability, and Pharmacokinetics Following Single and Multiple Intravitreal Administrations of KSI-301 in Subjects With wAMD, DME and RVO

Diabetic Macular Edema | Retinal Vein Occlusion | Wet Age-related Macular Degeneration

United States
Oncolys BioPharma Inc
Medigen Biotechnology Corporation

Unknown

Phase I Study to Evaluate the Safety and Efficacy of Telomelysin (OBP-301) in Patients With Hepatocellular Carcinoma

Carcinoma, Hepatocellular

Taiwan, Korea, Republic of
Mersin University

Completed

Does Diaphragm Electrical Activity Monitoring Predict Extubation Success in Children?

Pediatrics | Neurally Adjusted Ventilatory Assist | Diaphragm Electrical Activity
Sensei Biotherapeutics, Inc.

Withdrawn

SNS-301 Monotherapy in High Risk MDS and CMML

Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia (CMML)
Celldex Therapeutics

Completed

A Study to Evaluate CDX-301 (rhuFlt3L) in Healthy Volunteers

Healthy

United States
University of Michigan

Completed

Electrical Impedance Tomography for Optimization of Positive End-Expiratory Pressure: Acute Respiratory Distress Syndrome

Acute Respiratory Distress Syndrome | ARDS

United States
Czech Technical University in Prague

Completed

Spirometry Using Electrical Impedance Tomography (EIT)

Healthy

Czechia
Benitec Biopharma, Inc.

Recruiting

A Study to Evaluate the Safety and Clinical Activity of Intramuscular Doses of BB-301 Administered to Subjects With Oculopharyngeal Muscular Dystrophy With Dysphagia

Oculopharyngeal Muscular Dystrophy

United States
Neuramedy Co. Ltd.
Quotient Sciences

Not yet recruiting

Single and Multiple Ascending Dose Study to Assess Safety, Tolerability and Pharmacokinetics of NM-101

Parkinson Disease

United Kingdom
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Intra-Lymphatic STI-3031 Using the Sofusa DoseConnect Device for Treatment of In-Transit Melanoma, The Sofusa-2 Study

Melanoma | Metastatic Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Recurrent Metastatic Melanoma

United States
Jena University Hospital

Active, not recruiting

Imbalances of Regional Pulmonary Ventilation in Patients With Post-acute-COVID-19

Electric Impedance | COVID-19 Pneumonia | Post-acute COVID-19 Syndrome

Germany

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