Search clinical trials for: EPX-100 (Clemizole HCl)

Total 268 results

Epygenix

Completed

Study of Safety and Pharmacokinetics of Oral Doses of EPX-100 in Healthy Subjects.

Dravet Syndrome

United States
Epygenix
Forest Hills Lab; Liberyx Therapeutics

Recruiting

EPX-100 (Clemizole Hydrochloride) as Add-on Therapy to Control Convulsive Seizures in Patients With Dravet Syndrome (ARGUS)

Dravet Syndrome

United States, Canada, Spain, Georgia, Hungary
Epygenix

Not yet recruiting

EPX-100 (Clemizole Hydrochloride) as Adjunctive Therapy in Children With Lennox Gastaut Syndrome (LGS)

Lennox Gastaut Syndrome
OrthoTrophix, Inc

Completed

A Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 in Subjects With Mild to Moderate Patello-Femoral Osteoarthritis Involving Both Knees

Knee Osteoarthritis

United States
Sunovion Respiratory Development Inc.

Completed

A Study of the Efficacy and Safety of EP-101 ( (SUN101) in Subjects With Moderate to Severe Chronic Obstructive Pulmonary Disease (GOLDEN-2)

COPD

United States
Gem Pharmaceuticals

Completed

GPX-100 in Treating Patients With Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
OrthoTrophix, Inc

Completed

A Prospective Observational Study to Evaluate Long-term Changes in Cartilage Morphology in Subjects Who Previously Received TPX-100 or Placebo in Study TPX-100-1 for Patellar Osteoarthritis Involving Both Knees

Mild to Moderate Knee OA

United States
OrthoTrophix, Inc

Completed

A Study Evaluating the Safety and Efficacy of a Second Course of TPX-100 in Subjects Who Previously Received TPX-100 for Patellar Osteoarthritis Involving Both Knees

Knee Osteoarthritis
Rabin Medical Center

Unknown

Effect of Fish Oil on Surgery Pain After Knee Replacement Patients: Randomized, Prospective, Double Blind, Placebo Control Trial (EFOPaKR-01)

Rheumatoid Arthritis

Israel
Meir Medical Center

Completed

Use of APX 100 Device for Small-pupil Cataract Surgery and Intraoperative Floppy-iris Syndrome

Intraoperative Floppy Iris Syndrome | Miosis Disorder

Israel
Esperance Pharmaceuticals Inc

Completed

Pharmacodynamics (PD) and Pharmacokinetics (PK) Study of EP-100 in Advanced Solid Tumors

Advanced Solid Tumors | Solid Tumors

United States
Turino, Gerard, M.D.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Safety Study of CTX-100 Inhalation Solution (Formerly ETX-100)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Salvat

Completed

A Clinical Trial to Assess the Effect of HC-SVT-1001 and HC-SVT-1002 in the Surgical Treatment of Atrophic Pseudarthrosis of Long Bones (Bonecure) (Bonecure)

Pseudoarthrosis

Spain
Millendo Therapeutics US, Inc.

Terminated

A Study of ATR-101 for the Treatment of Endogenous Cushing's Syndrome

Cushing Syndrome

United States, United Kingdom
Engrail Therapeutics INC

Withdrawn

ENACT: A Study of ENX-101 as Adjunctive Treatment in Patients With Focal Seizures (ENACT)

Focal Epilepsy

United States
Engrail Therapeutics INC

Recruiting

ENCALM: A Study of ENX-102 as a Monotherapy Treatment in Patients With Generalized Anxiety Disorder (ENCALM)

Generalized Anxiety Disorder

United States
Contour Research

Completed

Examination of Circumferential Reduction

Overweight or Obesity

United States
CicloMed LLC
Cmed Clinical Services

Completed

Safety, Dose Tolerance, Pharmacokinetics, and Pharmacodynamics Study of CPX-POM in Patients With Advanced Solid Tumors

Advanced Solid Tumors

United States
Abbott

Completed

Study to Evaluate the Role of Itopride HCI in Patients With Irritable Bowel Syndrome With Predominant Constipation

Irritable Bowel Syndrome

Pakistan
Almirall, S.A.
Allergan

Completed

Double-Blind, Placebo-Controlled Study to Evaluate 3 Doses of a Novel Tetracycline in the Treatment of Facial Acne Vulgaris

Acne Vulgaris

United States
SparX Biotech(Jiangsu) Co., Ltd.

Not yet recruiting

Study of SPX-101 in Subjects With Advanced or Refractory Solid Tumors

Solid Tumors
Bayer

Completed

Continuous Dosing of BAY73-4506 in Patients With Advanced Malignancies

Neoplasm

United States
Tego Science, Inc.

Completed

Safety and Efficacy Study of TPX-105 for Correction of Nasojugal Groove

Tear Trough Eyelid Deformity

Korea, Republic of
Charleston Laboratories, Inc

Completed

A Study to Assess the Efficacy and Safety of Oral CL-H1T in the Treatment of Acute Migraine Pain

Pain | Nausea | Vomiting | Migraine | Aura

United States
Spyryx Biosciences, Inc.

Completed

A Safety Study of SPX-101 Inhalation Solution in Subjects With Cystic Fibrosis

Cystic Fibrosis

Canada
Gem Pharmaceuticals

Terminated

Study of GPX-100 in the Treatment of Metastatic Breast Cancer

Breast Cancer | Metastasis

United States, Bulgaria
Bellicum Pharmaceuticals
M.D. Anderson Cancer Center; The University of Texas Health Science Center,... and other collaborators

Completed

MTD Study of Vaccine BP-GMAX-CD1 Plus AP1903 to Treat Castrate Resistant Prostate Cancer

Castrate Resistant Prostate Cancer (CRPC)

United States
Dark Canyon Laboratories, LLC

Completed

A Safety and Efficacy Study of DCL-101 Compared to GoLYTELY

Bowel Preparation Before Colonoscopy

United States
University of Michigan

Terminated

OPTIMA-TBI Pilot Study (OPTIMA)

Mild Traumatic Brain Injury

United States
University Hospital Birmingham
Ortho Biotech, Inc.; Gambro Renal Products, Inc.

Completed

European Trial of Free Light Chain Removal by Extended Haemodialysis in Cast Nephropathy (EuLITE)

Multiple Myeloma | Kidney Failure | Cast Nephropathy

United Kingdom
Sandoz

Completed

A Relative Bioavailability Study of Metformin HCL Tablets, 1000 mg Under Fasting Conditions

Type 2 Diabetes
National Institute of Allergy and Infectious Diseases...

Completed

Safety of and Immune Response to the Experimental Preventive HIV Vaccine, EP HIV-1090, in Healthy, HIV-1 Uninfected Adults

HIV Infections

United States
Sunovion Respiratory Development Inc.

Completed

Study to Investigate the Dose Response, Safety and Efficacy of Nebulized EP-101(SUN101) in Patients With Chronic Obstructive Pulmonary Disease (COPD): GOLDEN-1 Study

Chronic Obstructive Pulmonary Disease

United States, United Kingdom
Spyryx Biosciences, Inc.

Completed

An Efficacy and Safety Study of SPX-101 Inhalation Solution in Subjects With Cystic Fibrosis ((HOPE-1))

Cystic Fibrosis

United Kingdom, Canada, France, Italy, Portugal
Phenex Pharmaceuticals AG
Medical University of Vienna

Completed

Safety Pilot Study of Farnesoid X Receptor (FXR) Agonist in Non-alcoholic Fatty Liver Disease (NAFLD) Patients

Non Alcoholic Fatty Liver Disease

Austria
National Institute of Allergy and Infectious Diseases...

Completed

Safety of and Immune System Response to an HIV Vaccine (EP HIV-1090) in HIV Uninfected Adults

HIV Infections

Botswana, United States
Gem Pharmaceuticals

Completed

Safety Study of GPX-150 in Patients With Solid Tumors

Advanced Solid Tumors - Phase 1 Population

United States
Gem Pharmaceuticals

Completed

Efficacy and Safety Study of GPX-150 to Treat Soft Tissue Sarcoma

Soft Tissue Sarcoma

United States
Cambium Medical Technologies LLC
University of Michigan; Duke University; Oregon Health and Science University; Stanford... and other collaborators

Completed

Topical Fibrinogen-Depleted Human Platelet Lysate in Patients With Dry Eye Secondary to Graft vs. Host Disease

Dry Eye | Graft-versus-host-disease | Ocular Discomfort

United States
InQpharm Group

Completed

IQP-CL-101 in IBS Management

Irritable Bowel Syndrome

Germany
Phenex Pharmaceuticals AG

Completed

Single Ascending Oral Dose Phase I Study With Px-102

Healthy

Germany
Phenex Pharmaceuticals AG

Completed

Multiple Ascending Oral Dose Phase I Study With Px-102

Healthy

Germany
Imperial College London

Not yet recruiting

Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) Trial (MAST)

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Chronic Myeloid Leukemia | Myelodysplastic Syndrome | Acute Leukemia of Ambiguous Lineage | Acute Lymphoblastic Leukaemia

United Kingdom
Acasti Pharma Inc.

Active, not recruiting

Single-dose to Evaluate the Pharmacokinetics of GTX-101 and Subcutaneous Injectable Bupivacaine in Healthy Subjects

Postherpetic Neuralgia

Canada
Alaunos Therapeutics

Completed

Safety Study of Adenovirus Vector Engineered to Express hIL-12 in Combination With Activator Ligand to Treat Melanoma

Melanoma

United States
Sun Yat-sen University

Unknown

Epi-keratoplasty Versus Collagen Cross-Linking in Progressive Keratoconus

Progressive Keratoconus

China
Actavis Inc.

Completed

A Relative Bioavailability Study of Sertraline HCl 100 mg Tablets Under Non-fasting Conditions

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Sertraline HCl 100 mg Tablets Under Fasting Conditions

Healthy

United States
Alaunos Therapeutics

Completed

A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Breast Cancer

Metastatic Breast Cancer

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety of and Immune System Response to an HIV Vaccine (EP HIV-1090) in HIV Infected Patients

HIV Infections

United States

3

Subscribe