Search clinical trials for: Emapalumab

Total 12 results

Swedish Orphan Biovitrum

Recruiting

Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE (EMERALD)

Systemic Lupus Erythematosus | Macrophage Activation Syndrome | Still Disease | Secondary Hemophagocytic Lymphohistiocytosis | SJIA | AOSD | MAS

United States, Belgium, Italy, Netherlands, United Kingdom, China, France, Spain, Czechia, Canada, Sweden, Japan, Germany, Poland
M.D. Anderson Cancer Center
Sobi, Inc.

Not yet recruiting

A Pilot Study of Emapalumab for the Treatment of CAR T-Cell Therapy-Associated Prolonged Cytopenia

Cytopenia

United States
Swedish Orphan Biovitrum

Completed

Study to Assess the Efficacy and Safety of Emapalumab in Primary Haemophagocytic Lymphohistiocytosis

Primary Hemophagocytic Lymphohistiocytosis

Spain, United States, United Kingdom, Germany, Italy, Sweden, Canada, Switzerland
Swedish Orphan Biovitrum

Active, not recruiting

A Post-authorization Study to Describe the Safety and Efficacy of Emapalumab for the Treatment of pHLH in Treatment Experienced Chinese Patients

Primary Hemophagocytic Lymphohistiocytosis

China
Swedish Orphan Biovitrum

Completed

A Study to Investigate the Safety and Efficacy of Emapalumab, an Anti-IFN-gamma mAb in Patients With Systemic Juvenile Idiopathic Arthritis (sJIA) or Adult-onset Still's Disease (AOSD) Developing Macrophage Activation Syndrome/Secondary HLH (MAS/sHLH)

Arthritis, Juvenile | Lymphohistiocytosis, Hemophagocytic | Macrophage Activation Syndrome | Adult Onset Still Disease

United States, Spain, United Kingdom, France, Italy
Swedish Orphan Biovitrum
Seventh Framework Programme

Completed

A Study for Long-term Follow-up of Hemophagocytic Lymphohistiocytosis (HLH) Participants Who Received Treatment With Emapalumab (NI-0501), an Anti-interferon Gamma Monoclonal Antibody

Hemophagocytic Lymphohistiocytosis

United States, France, Italy, Spain, United Kingdom
Swedish Orphan Biovitrum
Light Chain Bioscience - Novimmune SA

Terminated

A Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Emapalumab in Adult Patients With HLH

Hemophagocytic Lymphohistiocytoses

United States
Swedish Orphan Biovitrum
PRA Health Sciences; Cromsource; BioMérieux; Q2 Solutions; Cytel Inc.; ABF Pharmaceutical...

Terminated

Study to Investigate the Pharmacokinetics, Pharmacodynamics and Assess the Efficacy and Safety to Support Dose Selection of Emapalumab in Pre-empting Graft Failure in Patients at High Risk After HSCT.

Graft Failure

Canada, Australia, Israel
Instituto Bioclon S.A. de C.V.
University of Arizona

Completed

A Comparison of Crotalinae Equine Immune F(ab)2 Antivenom (Anavip) and Crotalidae Polyvalent Immune Fab,

Blood Coagulation Disorders | Snake Bite

United States
Swedish Orphan Biovitrum

Terminated

Efficacy and Safety of Emapalumab and Anakinra in Reducing Hyperinflammation and Respiratory Distress in Patients With COVID-19 Infection.

SARS-CoV-2

United States, Italy
Memorial Sloan Kettering Cancer Center
Sobi, Inc.

Recruiting

A Study of Treatment of Inflammation Before Stem Cell Transplant in People With a Primary Immune Regulatory Disorder (PIRD) and/or an Autoinflammatory Condition

Immune System Diseases | Autoimmune Lymphoproliferative | Primary Immune Regulatory Disorder

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease (CGD) With an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined With Cytokine (IL-6, +/- IFN-gamma) Antagonists

Chronic Granulomatous Disease

United States

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