Search clinical trials for: Endotoxin

Total 85 results

University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of a 10,000 EU Dose of Endotoxin in Allergic and Mildly Asthmatic Adults

Asthma | Rhinitis, Allergic, Perennial | Rhinitis, Allergic, Seasonal

United States
University of Alabama at Birmingham
American Fibromyalgia Syndrome Association

Completed

The Innate Central Nervous System Immune Response to an Experimental Immune Challenge in People With Fibromyalgia

Fibromyalgia

United States
University of California, Los Angeles
National Institute of Mental Health (NIMH)

Completed

Inflammation-Induced Depressed Mood: The Role of Social Neurocognitive Mechanisms

Depression

United States
University of California, Los Angeles

Completed

Cytokine-Associated Depression and Social Pain

Depression

United States
University of California, Los Angeles
National Institute on Aging (NIA)

Recruiting

Aging and Reward System Response to Inflammation and Anxiety Study (ARIA)

Depression | Inflammation | Anhedonia | Anxiety | Aging

United States
Radboud University Medical Center

Completed

Determining the Fingerprint of Endotoxin Tolerance (100LPS)

Sepsis | Endotoxemia | Systemic Inflammation | Immunosuppresion

Netherlands
Ohio State University
National Institute of Mental Health (NIMH)

Not yet recruiting

Inflammatory Challenge in Human Aggression. (LPSS)

Intermittent Explosive Disorder

United States
Michael Irwin, MD

Completed

Sleep and Healthy Aging Research for Depression (SHARE-D) Study (SHARE-D)

Depression in Old Age

United States
University of California, Los Angeles

Completed

Sleep and Healthy Aging Research on Depression for Younger Women

Depression | Anhedonia

United States
Robert J Noveck, M.D.
Foundation for the National Institutes of Health

Completed

Dose-Related Inflammatory Effects of Intravenous Endotoxin in Humans

Healthy

United States
Aarhus University Hospital

Completed

Peripheral Effects of Endotoxin on Insulin Resistance

Healthy

Denmark
Karolinska Institutet
The Swedish Research Council; University of California, San Francisco; Swedish... and other collaborators

Completed

Inflammation and Brain Function - Main Study

Sickness Behavior
University of Lausanne
Centre Hospitalier Universitaire Vaudois

Completed

Lactate Metabolism After an Endotoxin Challenge in Healthy Humans

Sepsis

Switzerland
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Inflammation and the Metabolic Syndrome in Humans (LPS)

Metabolic Syndrome X

United States
Rigshospitalet, Denmark

Unknown

Study of Renal Blood Flow During Human Endotoxemia

Healthy | Type 2 Diabetes | Endotoxemia

Denmark
Herlev Hospital

Unknown

Low-Dose Endotoxemia and the Acute Phase Response

Sepsis | Endotoxemia

Denmark
John Sundy

Completed

Role of TLR4 in Environmental Asthma

Asthma

United States
John Sundy

Terminated

Genetics of Asthma - Bronchoscopy Studies

Healthy | Atopic Asthma

United States
Pfizer

Terminated

A Study To Evaluate The Safety And Effects On The Body Of An Investigational Drug Using An Endotoxin-Induced Inflammatory Response Model (POM)

Healthy

United States
Karolinska Institutet
The Swedish Research Council; University of California, San Francisco; Swedish... and other collaborators

Completed

Inflammation and Brain Function - Pilot Study

Sickness Behavior
University of North Carolina, Chapel Hill
National Institutes of Health (NIH)

Terminated

Safety Study of 20,000 EU of Clinical Center Reference Endotoxin in Allergic Adults With and Without Mild Asthma

Mild Allergic Rhinitis | Mild Allergic Rhinitis With Mild Asthma

United States
University of North Carolina, Chapel Hill
National Institute of Environmental Health Sciences (NIEHS)

Completed

Inhalation of 20,000 Endotoxin Units(EU) of Clinical Center Reference Endotoxin in Healthy Volunteers (Entox)

Healthy Adults

United States
Rigshospitalet, Denmark
The Ministry of Science, Technology and Innovation, Denmark; H:S, Denmark; The...

Completed

Cerebral Blood Flow and Metabolism During Hypoxia and Endotoxemia

Healthy | Hypoxia | Endotoxemia

Denmark
University of California, Los Angeles

Completed

An Inflammatory Challenge Using Endotoxin

Inflammatory Response | Alcohol Use Disorder | Craving | Depressed Mood

United States
University of Aarhus

Completed

The Effects of Amino Acid Supplement During Acute Inflammation.

Metabolic Diseases | Inflammation | Febrile Illness Acute

Denmark
Radboud University Medical Center

Completed

The Effects of Concentration/Meditation on the Innate Immune Response During Human Endotoxemia

Innate Immune Response

Netherlands
Medical University of Vienna

Completed

Effect of Retaron® on Oxygen Induced Retinal Vasoconstriction in LPS Induced Inflammatory Model in Humans

Healthy Subjects | Imparied Retinal Vascular Reactivity

Austria
University of North Carolina, Chapel Hill
United States Department of Defense; RTI International; Environmental Protection...

Completed

Effects of 20,000 EU of Clinical Center Reference Endotoxin (CCRE) Versus Placebo(ENDOHEART) (Endoheart)

Healthy

United States
Aarhus University Hospital
University of Aarhus; Lundbeck Foundation

Completed

Endotoxin & Cytokines. Do Protein Loss and Metabolic Effects Depend on Central Nervous System (CNS) Activation of Stress Hormones or on Local Mechanisms in Muscle and Fat?

Glucose Metabolism Disorders | Inflammation

Denmark
National Institutes of Health Clinical Center (CC)

Enrolling by invitation

Effects of Bronchial Segmental Endotoxin Instillation in Humans

Acute Lung Inflammation

United States
Radboud University Medical Center

Completed

The Effects of Immunostimulation With GM-CSF or IFN-y on Immunoparalysis Following Human Endotoxemia

Sepsis | Inflammation | Endotoxemia | Multi Organ Dysfunction Syndrome

Netherlands
Chinese University of Hong Kong

Completed

Bacteria Endotoxin in Peritoneal Dialysis Effluent as a Predictor of Relapsing, Recurrent, and Repeat Peritonitis

Peritoneal Dialysis Associated Peritonitis

Hong Kong
University of North Carolina, Chapel Hill
National Institute of Environmental Health Sciences (NIEHS)

Terminated

Response of Airway Cells to 20,000 EU of Endotoxin in Normal Adults

Healthy Controls

United States
Washington University School of Medicine
Doris Duke Charitable Foundation

Completed

Assessing NOS Uptake With PET Imaging in Lung Inflammation

Lung Inflammation

United States
Washington University School of Medicine
Barnes-Jewish Hospital

Completed

PET Imaging of Endotoxin-induced iNOS Activation

Pneumonia

United States
Fraunhofer-Institute of Toxicology and Experimental...

Terminated

Effect of an Immunotoxin on Activated Human Macrophages in Those With Allergic Rhinitis or Mild Intermittent Asthma

Rhinitis | Bronchial Asthma | Atopy

Germany
Karolinska Institutet
Danderyd Hospital

Completed

Endotoxin-induced Inflammatory and Behavioral Responses and Predictors of Individual Differences

Sickness Behavior
University of California, Los Angeles

Completed

Sleep Health, Inflammation, and Emotion Study (SHINE)

Depression

United States
Radboud University Medical Center
Exponential Biotherapies Inc.

Completed

PK/PD of EA-230 During Endotoxemia

Endotoxemia | Systemic Inflammatory Response

Netherlands
University of North Carolina, Chapel Hill
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

A Study of Inhalation of 20,000 EU CCRE in Normal Volunteers Compared to Allergic Asthmatic Individuals (Endomac)

Hypersensitivity | Asthma

United States
National Institute of Environmental Health Sciences...
National Center for Research Resources (NCRR)

Completed

The Genetics of Environmental Asthma

Asthma

United States
Rigshospitalet, Denmark

Completed

Study of Gene Activity in Fat and Muscle in Diabetics and Healthy Controls

Healthy | Type 2 Diabetes | Endotoxemia

Denmark
University of Foggia

Completed

The Diagnostic and Prognostic Value of Presepsin in Sepsis

Septic Shock

Italy
University of North Carolina, Chapel Hill
Environmental Protection Agency (EPA)

Completed

Systemic Inflammatory Response to CCRE (Endoscreen)

Healthy

United States
University of Aarhus

Completed

Effects of Free Fatty Acids and 3-hydroxybutyrate on Protein, Glucose, Lipid Metabolism and Intracellular Signals.

Systemic Inflammatory Response Syndrome

Denmark
Radboud University Medical Center
UMC Utrecht

Completed

The Effects of Human Endotoxemia on Functional Capacity of Hematopoietic Stem and Progenitor Cells (LPS-BM)

Sepsis, Endotoxemia, Immunosuppression

Netherlands
National Jewish Health

Not yet recruiting

Nasal Inflammation Following Endotoxin Challenge in Patients With Asthma (Nasal-LPS)

Asthma | Asthma; Eosinophilic

United States
Rutgers, The State University of New Jersey

Completed

Inflammation and the Host Response to Injury (In Healthy Volunteers) (Mono)

Immune System

United States
Laureate Institute for Brain Research, Inc.

Completed

Lipopolysaccharide (LPS) Challenge in Depression

Major Depressive Disorder

United States
Rigshospitalet, Denmark
Bispebjerg Hospital

Completed

Autonomic Nervous Activity During the Systemic Inflammatory Response in Trained and Untrained Healthy Volunteers

Systemic Inflammatory Response Syndrome

Denmark

Search clinical trials for: Endotoxin

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