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Search clinical trials for: Entacapone

Total 56 results

NCT04246437

Recruiting

[18F]F-DOPA Imaging in Patients With Autonomic Failure

Conditions: Autonomic Failure; Pure Autonomic Failure; Parkinson Disease; Multiple System Atrophy; Dementia With Lewy Bodies
NCT04006769

Not yet recruiting

Entacapone Combination With Imatinib for Treatment of GIST

Conditions: Gastrointestinal Stromal Tumor, Malignant
NCT03103399

Completed

Efficacy and Tolerability of Nebicapone in Parkinson's Disease Patients With "Wearingoff" Phenomenon

Conditions: Parkinson Disease
NCT03094156

Completed

Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics

Conditions: Parkinson Disease
NCT03091868

Completed

Pharmacokinetics of Rising Single-doses of BIA 6-512 and Their Effect on the Levodopa Pharmacokinetics

Conditions: Parkinson Disease
NCT02994719

Active, not recruiting

Gait Analysis in Neurological Disease

Conditions: Parkinson's Disease; Parkinsonian Disorders; Atypical Parkinson Disease; Progressive Supranuclear Palsy; Multiple System Atrophy; Corticobasal Degeneration; Gait, Frontal; Huntington Disease
NCT02834507

Completed

Effect of Two Multiple-dose Regimens of BIA 3-202 on the Pharmacokinetics and Motor Response of Levodopa, and on the Erythrocyte Comt Activity in Parkinson's Disease Patients

Conditions: Parkinson's Disease (PD)
NCT02764125

Completed

Efficacy and Safety Proof of Concept Study in Patients With Parkinson's Disease and End-of-dose Wearing-off (COMPOC)

Conditions: Parkinson's Disease
NCT02554734

Completed

Pharmacokinetic Study in Healthy Volunteers

Conditions: Parkinson's Disease
NCT02452606

Unknown status

Clock and Narcolepsy Genetic Variants and the Effects of Stalevo® (Levodopa/Carbidopa/Entacapone) on Sleep Disorders in Parkinson's Disease

Conditions: Parkinson Disease; Sleep Disorders
NCT02448914

Completed

A Study to Compare Plasma Levels of Levodopa, Carbidopa and Entacapone After TRIGEL or Duodopa Infusion in PD Patients

Conditions: Parkinson's Disease
NCT02349243

Unknown status

Effect of Entacapone on Bodyweight Loss in Obese Population

Conditions: Obesity
NCT02170376

Completed

The Effect of BIA 9-1067 at Steady-state on the Levodopa Pharmacokinetics

Conditions: Parkinson's Disease (PD)
NCT02070887

Unknown status

Inhibiting COMT in Parkinson's Disease

Conditions: Parkinson's Disease
NCT02058966

Completed

Pilot Study of Entacapone for Methamphetamine Abuse

Conditions: Methamphetamine Dependence
NCT01840423

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ODM-104 in Healthy Volunteers

Conditions: Healthy
NCT01766258

Completed

Efficacy and Safety Proof of Concept Study in Patients With Parkinson's Disease and End-of-dose Motor Fluctuations

Conditions: Parkinson's Disease
NCT01688089

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ODM-103 in Healthy Volunteers

Conditions: Healthy
NCT01568073

Completed

Efficacy and Safety of BIA 9-1067 in Idiopathic Parkinson's Disease Patients With "Wearing-off" Phenomenon

Conditions: Parkinson's Disease
NCT01520727

Completed

A Single Oral Ascending Dose Study of BIA 9-1067 in Healthy Male Subjects

Conditions: Parkinson Disease
NCT01519284

Completed

Study of BIA 9-1067 to Investigate Its Effect on Levodopa Pharmacokinetic

Conditions: Parkinson Disease
NCT01468012

Completed

Imaging the Neurobiology of Behavioral and Medication Treatment for Cocaine Dependence

Conditions: Cocaine Dependence
NCT01437293

Completed

Behavioral and Physiological Effects of Cocaine in Cocaine-dependent Participants Treated With Levodopa in Combination With Carbidopa and Entacapone (LCE)

Conditions: Cocaine Abuse
NCT01296464

Completed

Comparing Different Levodopa/Carbidopa/Entacapone Treatment Regimens

Conditions: Parkinson's Disease
NCT01158950

Completed

A Study of Neural Circuit Responses to Catechol-O-methyl Transferase (COMT) Inhibitors

Conditions: Impulsive Behavior
NCT01130493

Completed

A Study to Compare IPX066 and Carbidopa/Levodopa/Entacapone (CLE) Followed by an Open-Label Safety Study of IPX066

Conditions: Parkinson's Disease
NCT01070628

Completed

Levodopa Concentration Profile With Stalevo 75/125 mg

Conditions: Parkinson's Disease
NCT00906828

Completed

Pharmacokinetics of Levodopa/Carbidopa Infusion With and Without Oral Catechol-O-methyl Transferase (COMT) Inhibitors

Conditions: Parkinson Disease
NCT00693862

Completed

Pharmacokinetic Study With Repeated Doses of Stalevo

Conditions: Pharmacokinetics
NCT00642356

Terminated

Carbidopa/Levodopa/Entacapone Versus Immediate Release (IR) Carbidopa/Levodopa on Non-motor Symptoms in Patients With Idiopathic Parkinson's Disease and Demonstrating Non-motor Symptoms of Wearing Off

Conditions: Parkinson's Disease
NCT00601978

Withdrawn

Carbidopa/Levodopa Versus Carbidopa/Levodopa/Entacapone on Markers of Event Related Potentials (ERPs) in Patients With Idiopathic Parkinson's Disease (PD) and End-of-dose Wearing Off

Conditions: Parkinson's Disease
NCT00562198

Terminated

PET-Study: Effects of Single Doses of Stalevo and Levodopa/Carbidopa on Striatal 11C-Raclopride Binding

Conditions: Parkinson´s Disease
NCT00547911

Terminated

Augmenting Effects of L-DOPS With Carbidopa and Entacapone

Conditions: Parkinson Disease; Multiple System Atrophy; Autonomic Nervous System Diseases
NCT00537017

Completed

Follow Up Safety Study of SCH 420814 in Subjects With Parkinson's Disease (P05175)

Conditions: Parkinson Disease; Neurodegenerative Diseases; Central Nervous System Diseases; Movement Disorders; Brain Diseases
NCT00491998

Completed

PK, PD and Safety of Multiple Doses of V1512 Tablets in PD Patients Compared to Standard Levodopa/Carbidopa Oral Tablets

Conditions: Parkinson's Disease
NCT00415740

Completed

Bioequivalence Study of Carbidopa/Levodopa/Entacapone Combination vs. Carbidopa/Levodopa Combination Plus Entacapone in Healthy Volunteers

Conditions: Healthy
NCT00415831

Completed

Bioequivalence Study of Carbidopa/Levodopa/Entacapone Combination vs. Carbidopa/Levodopa Combination Plus Entacapone in Healthy Volunteers

Conditions: Healthy
NCT00415844

Completed

Bioequivalence Study of Carbidopa/Levodopa/Entacapone Combination vs. Carbidopa/Levodopa Combination Plus Entacapone Under Fasting Conditions in Healthy Volunteers

Conditions: Healthy
NCT00415922

Completed

Bioequivalence Study of Carbidopa/Levodopa/Entacapone Combination vs. Carbidopa/Levodopa Combination Plus Entacapone in Healthy Volunteers

Conditions: Healthy
NCT00406029

Completed

Dyskinesia in Parkinson's Disease (Study P04501)

Conditions: Parkinson Disease; Movement Disorders; Central Nervous System Diseases; Neurodegenerative Diseases; Brain Diseases
NCT00391898

Completed

Efficacy of Levodopa/Carbidopa/Entacapone vs Levodopa/Carbidopa in Parkinson's Disease Patients With Early Wearing-off

Conditions: Parkinson's Disease
NCT00373087

Completed

COMT Polymorphism and Entacapone Efficacy

Conditions: Parkinson's Disease
NCT00360308

Terminated

Efficacy, Safety and Tolerability of E2007 in Levodopa Treated Parkinson's Disease Patients With Motor Fluctuations

Conditions: Parkinson's Disease
NCT00262470

Active, not recruiting

Treatment of Orthostatic Intolerance

Conditions: Tachycardia; Chronic Orthostatic Intolerance
NCT00247247

Completed

Comtess® Versus Cabaseril® as Add-on to Levodopa in the Treatment of Parkinsonian Patients Suffering From Wearing- Off.

Conditions: Parkinson's Disease
NCT00245700

Completed

Adherence of Stalevo, Entacapone and Levodopa

Conditions: Parkinson's Disease
NCT00237263

Completed

An Extension Study of Entacapone in Patients With Parkinson's Disease With End-of-dose Wearing-off. This Study is Not Recruiting in the United States

Conditions: Parkinson's Disease
NCT00219284

Completed

Effects of Carbidopa/Levodopa/Entacapone on Motor Function and Quality of Life in Patients With Parkinson's Disease

Conditions: Parkinson's Disease With End of Dose Wearing Off
NCT00199394

Completed

A Study of Istradefylline (KW-6002) for the Treatment of Parkinson's Disease

Conditions: Parkinson's Disease
NCT00200447

Completed

An Open-Label Feasibility/Pilot Study With [123I]-IBZM SPECT (DOPA-SYN)

Conditions: Parkinson's Disease