Search clinical trials for: Ertugliflozin OC Slow

Total 7328 results

Merck Sharp & Dohme LLC
Pfizer

Completed

Study To Estimate The Relative Bioavailability of Ertugliflozin (PF-04971729, MK-8835) in Healthy Adult Participants (MK-8835-039)

Healthy
Merck Sharp & Dohme LLC
Pfizer

Completed

Study of Safety and Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes And Hypertension (MK-8835-042)

Hypertension | Diabetes Mellitus, Type 2
Ocellaris Pharma, Inc.

Recruiting

A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers

Sarcoma | Neoplasms | Renal Cell Carcinoma | Cervical Cancer | Cancer | Hepatocellular Carcinoma | Gastric Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Squamous Cell Carcinoma of Head and Neck | Bladder Cancer | Triple Negative Breast Cancer | Urothelial Carcinoma | Merkel Cell Carcinoma | Squamous... and other conditions

Canada
Shenzhen Geno-Immune Medical Institute

Suspended

Intervention of Ovarian Cancer With Antigen-specific Engineered Immune Effectors

Ovarian Cancer

China
University of California, Los Angeles
Virtually Better, Inc.

Completed

Initial Development and Dissemination of OC-Go (OC-GoPhaseI)

Obsessive-Compulsive Disorder

United States
Shenzhen Geno-Immune Medical Institute

Unknown

Engineered Immune Effectors Against Ovarian Cancer

Ovarian Cancer

China
Oyster Point Pharma, Inc.

Completed

Evaluation of the Long Term Follow up of the Efficacy of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye Disease

Long Term Follow up Dry Eye Disease

United States
Merck Sharp & Dohme LLC
Pfizer

Active, not recruiting

Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

Type 2 Diabetes Mellitus

United States, Belgium, Canada, Colombia, Costa Rica, Dominican Republic, France, Guatemala, Hungary, Israel, Italy, Malaysia, Mauritius, Mexico, Philippines, Poland, Russian Federation, Saudi Arabia, Turkey, Ukraine, United Arab... and more
Shenzhen Geno-Immune Medical Institute

Unknown

Genetically Modified T Cells Against Ovarian Cancer

Ovarian Cancer

China
OcuCure Therapeutics, Inc.

Completed

Phase I Study Assessing the Ocular and Systemic Safety and Tolerability of OC-10X

Proliferative Diabetic Retinopathy (PDR)

Bangladesh
Bispebjerg Hospital
University College Absalon; Danske Fysioterapeuter

Active, not recruiting

Blood Flow Restriction Training for Treatment of Chronic Patellar Tendinopathy

Jumper's Knee | Patellar Tendinopathy

Denmark
Lumbini Medical College

Completed

Single Setting ERCP and Laparoscopic Cholecystectomy is a Safe Procedure in Patients With Cholecysto-Choledocholithiasis

Choledocholithiasis With Cholecystitis With Obstruction | Choledocholithiasis With Acute and Chronic Cholecystitis | Cholelithiasis With Acute and Chronic Cholecystitis
Merck Sharp & Dohme LLC
Pfizer

Completed

Effects of Once and Twice Daily Dosing Regimen of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes (MK-8835-040)

Diabetes Mellitus, Type 2 | Adult
BIXINK Therapeutics Co., Ltd.

Recruiting

An ERP-based Mobile Intervention as an Adjunctive Treatment for OCD

Obsessive-Compulsive Disorder | Obsessive-compulsive Disorders and Symptoms

United States
Oyster Point Pharma, Inc.

Completed

Evaluation of the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (the RAINIER Study)

Dry Eye Disease

United States
Oyster Point Pharma, Inc.

Completed

Clinical Trial to Evaluate the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (The PEARL Study)

Dry Eye Disease

United States
National Taiwan University Hospital

Unknown

Screening for Stomach Diseases and Colorectal Neoplasms With the Fecal Testing

Colorectal Cancer | Stomach Disease

Taiwan
Merck Sharp & Dohme LLC
Pfizer

Completed

A Phase 1 Study of Ertugliflozin in Healthy Male Participants (MK-8835-020)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC
Pfizer

Completed

A Study to Evaluate the Efficacy and Safety of Ertugliflozin in Asian Participants With Type 2 Diabetes and Inadequate Glycemic Control on Metformin Monotherapy (MK-8835-012)

Type 2 Diabetes Mellitus
University of California, Los Angeles
Virtually Better, Inc.

Completed

Randomized Controlled Trial of Standard ERP and OC-Go (OC-GoPhaseII)

Obsessive-Compulsive Disorder

United States
Merck Sharp & Dohme LLC
Pfizer

Completed

Pharmacokinetics, Safety, and Tolerability of Ertugliflozin (MK-8835/PF-04971729) in Participants With Hepatic Impairment and in Healthy Participants (MK-8835-014)

Type 2 Diabetes Mellitus | Hepatic Impairment
Merck Sharp & Dohme LLC
Pfizer

Completed

A Study of the Efficacy and Safety of Ertugliflozin in Participants With Type 2 Diabetes Mellitus With Stage 3 Chronic Kidney Disease Who Have Inadequate Glycemic Control on Antihyperglycemic Therapy (MK-8835-001)

Type 2 Diabetes Mellitus
University of California, San Diego

Not yet recruiting

Head to Head Mailed Cologuard to Mailed FIT

Colorectal Cancer
Nottingham University Hospitals NHS Trust

Completed

4-week Serial FIT Analysis in Patients With CRC

Colorectal Cancer

United Kingdom
Sato Ashida
University of Michigan; National Institute on Aging (NIA); Boston College; University... and other collaborators

Completed

Building a Bridge (BAB) Between Clinical and Community Care (BAB)

Caregiver Burden

United States
Aga Khan University

Completed

Effectiveness of Nigella Sativa (Kalonji) Seed in Dyslipidemia

Hypertension | Diabetes Mellitus | Hypercholesterolemia | Metabolic Syndrome X

Pakistan
Karaman Training and Research Hospital

Recruiting

Effect of Preoperative Oral Carbohydrate Loading on Elderly Patient Quality of Recovery in Total Knee Arthroplasty

Quality Of Recovery

Turkey
Merck Sharp & Dohme LLC
Pfizer

Completed

Study Of Safety And Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes (MK-8835-016)

Diabetes Mellitus, Type 2
Merck Sharp & Dohme LLC
Pfizer

Completed

Safety and Efficacy of Ertugliflozin in the Treatment of Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin and Sitagliptin (MK-8835-006; VERTIS SITA2)

Type 2 Diabetes Mellitus
Amsterdam UMC, location VUmc

Completed

Renal Oxygenation, Oxygen Consumption and Hemodynamic Kinetics in Type 2 DIabetes: an Ertugliflozin Study. (ROCKIES)

Type 2 Diabetes Mellitus | Diabetic Nephropathy | Diabetic Kidney Disease | Renal Hypoxia | Renoprotection | SGLT2 Inhibitor | Ertugliflozin

Netherlands
Getz Pharma

Not yet recruiting

Effect of Erugliflozin On Liver Fat, Liver Fibrosis and Glycemic Control in Type II DM Patients With NASH/NAFLD (Ertu-NASH)

Body Weight Changes | Liver Fat | Tolerance | Liver Fibrosis | Glycemic Control | Waist Circumference
AdventHealth Translational Research Institute

Recruiting

Low-CArbohydrate Diet and SGLT2-INhibitOr to Achieve Moderate Ketosis in Healthy Volunteers (CASINO)

Ketones, Metabolism

United States
Medical University of Graz
Medical University of Vienna; Landesklinkum Wiener Neustadt; Klinik Ottakring; Medical... and other collaborators

Terminated

Ertugliflozin to Reduce Arrhythmic Burden in ICD/CRT patientS (ERASe-Trial) - a Phase III Study (ERASE)

Implantable Cardioverter-Defibrillators | Heart Failure With Reduced Ejection Fraction | Cardiac Resynchronization Therapy | Heart Failure With Mid Range Ejection Fraction

Austria
University Hospitals Cleveland Medical Center

Terminated

Evaluating Metabolic Mechanisms of Ertugliflozin in Diabetes & Heart Failure (EMMED-HF)

Diabetes Mellitus, Type 2 | Heart Failure, Diastolic

United States
National Cancer Institute (NCI)

Terminated

Phase II Study of the Efficacy and Toxicity of Ontak(Registered Trademark) (Denileukin Diftitox) in the Therapy of Adult T-Cell Leukemia

Leukemia, Adult T-Cell

United States
Merck Sharp & Dohme LLC
Pfizer

Completed

A Study of the Efficacy and Safety of Ertugliflozin Monotherapy in the Treatment of Participants With Type 2 Diabetes Mellitus and Inadequate Glycemic Control Despite Diet and Exercise (MK-8835-003, VERTIS MONO)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC
Pfizer

Completed

A Single Escalating Dose Study Of Ertugliflozin (PF-04971729, MK-8835) Under Fed and Fasted Conditons In Healthy Volunteers (MK-8835-036)

Type 2 Diabetes Mellitus
Baylor College of Medicine
University of Pittsburgh; Brown University

Recruiting

Measuring Automated Behavioral Observations & Vocal Expressions (ABOVE) (ABOVE)

Obsessive-Compulsive Disorder | OCD

United States
Amsterdam UMC, location VUmc
University of Colorado, Denver; Merck Sharp & Dohme LLC

Not yet recruiting

DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study (DESIGN)

Hypertension | Diabetes Mellitus | Diabetic Kidney Disease
University of North Carolina, Chapel Hill
National Institute of Mental Health (NIMH)

Completed

Continuous Oral Contraceptive Treatment in Premenstrual Dysphoric Disorder (PMDD) (PMDD)

Premenstrual Dysphoric Disorder

United States
Merck Sharp & Dohme LLC
Pfizer

Completed

A Multiple Dose Study Of Ertugliflozin (PF-04971729, MK-8835) In Otherwise Healthy Overweight And Obese Volunteers (MK-8835-037)

Healthy Volunteer
Universidad Vina del Mar

Completed

Effects of Oral Contraceptives on DNIC in Non-painful Healthy Women

Contraceptive Usage | Diffuse Noxious Inhibitory Control

Chile
Kiyuk Chang
Seoul St. Mary's Hospital; Pusan National University Hospital; Korea University... and other collaborators

Recruiting

SGLT2 Inhibitors on Clinical Outcomes and Left Ventricular Remodeling in Type 2 Diabetic Patients With Acute Myocardial Infarction, a Prospective, Multi-center Registry Study (RECORD-AMI)

Myocardial Infarction | Diabetes Mellitus, Type 2

Korea, Republic of
Navy General Hospital, Beijing

Completed

Maternal Oxygen Administration for Fetal Distress

Fetal Distress | Oxygen Inhalation Therapy | Second Stage of Labour

China
Merck Sharp & Dohme LLC
Pfizer

Completed

Ertugliflozin vs. Glimepiride in Type 2 Diabetes Mellitus (T2DM) Participants on Metformin (MK-8835-002)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC
Pfizer

Completed

Ertugliflozin and Sitagliptin Co-administration Factorial Study (VERTIS FACTORAL, MK-8835-005)

Type 2 Diabetes Mellitus
M.D. Anderson Cancer Center

Completed

High-Flow Oxygen for Dyspnea in Hospitalized Cancer Patients

Cancer

United States
Riphah International University

Recruiting

Comparison Between Blood Flow Resistance and Slow Motion Strength Training in Wrestlers

Sports

Pakistan
Bristol-Myers Squibb

Completed

The Effect of BMS-986142 on the Pharmacokinetics of a Combined Oral Contraceptive (OC) Containing Ethinyl Estradiol (EE) and Norethindrone Acetate (NET) in Healthy Female Subjects

Arthritis

United States
Merck Sharp & Dohme LLC
Pfizer

Completed

A Study To Evaluate The Efficacy And Safety Of Ertugliflozin In Participants With Type 2 Diabetes Mellitus And Inadequate Glycemic Control On Metformin Monotherapy (MK-8835-007).

Type 2 Diabetes Mellitus

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