Search clinical trials for: Estetrol oral tablet

Total 13614 results

Estetra
ICON Clinical Research

Completed

Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort)

Vasomotor Symptoms | Menopausal Symptoms

United States, Canada
Pantarhei Oncology B.V.

Completed

Evaluation of Effects of Estetrol on Testosterone Suppression and Quality of Life in Prostate Cancer Patients Treated With an LHRH Agonist.

Prostatic Neoplasm

Netherlands
Estetra
ICON Clinical Research

Active, not recruiting

Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort Study I)

Vasomotor Symptoms | Menopausal Symptoms

Spain, United States, Argentina, Lithuania, Poland, Italy, Hungary, United Kingdom, Romania, Czechia, Brazil, Canada, Russian Federation, Slovakia
Tasly Pharmaceutical Group Co., Ltd

Completed

Study of Jitongning Tablet to Treat Spondyloarthritis

Spondyloarthritis

China
Harmony Biosciences, LLC

Active, not recruiting

A Phase 2 Study to Evaluate the Safety and Efficacy of Pitolisant in Patients With Prader-Willi Syndrome, Followed by an Open Label Extension

Prader-Willi Syndrome

United States
Fulcrum Therapeutics

Completed

Relative Bioavailability and Food Effect Study of Losmapimod 15 mg Tablets

Healthy Adult Subjects

United States
Paratek Pharmaceuticals Inc

Active, not recruiting

Oral Omadacycline vs. Placebo in Adults With NTM Pulmonary Disease Caused by Mycobacterium Abscessus Complex (MABc)

Mycobacterium Infections, Nontuberculous | Nontuberculous Mycobacterial Lung Disease | Mycobacterium Abscessus Infection | Nontuberculous Mycobacterial Pulmonary Infection

United States
Rigshospitalet, Denmark

Completed

The Association Between Hyponatremia and Osteoporosis in Patients With Epilepsy.

Hyponatremia | Metabolic Bone Disease

Denmark
Donesta Bioscience

Completed

Effect of Food on the Bioavailability of 30 mg Estetrol (E4) Tablet in Healthy Postmenopausal Female Volunteers

Food-effect

Bulgaria
Pantarhei Bioscience

Completed

Feasibility Study Into the Contraceptive Effect of Estetrol

Healthy

Netherlands
Pantarhei Bioscience

Completed

Study to Evaluate 3 Dosages of Estetrol After 28 Days Administration in Healthy Postmenopausal Women

Healthy

Netherlands
Vaxart

Completed

Safety & Immunogenicity Study of Ad5 Based Oral Norovirus Vaccines (VXA-NVV-103)

Norovirus Infection

United States
Estetra

Completed

Cycle Control Assessment of a Combined Oral Contraceptive Containing Estetrol and a Progestin P1 or P2 (FIESTA)

Contraception

Finland
EicOsis Human Health Inc.

Recruiting

Safety, Tolerability, and Pharmacokinetics of Multiple Doses of Oral EC5026 in Healthy Subjects

Healthy Subjects

New Zealand
Cara Therapeutics, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of CR845 in Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States
Harmony Biosciences, LLC

Active, not recruiting

Safety and Efficacy of Pitolisant on Excessive Daytime Sleepiness and Other Non-Muscular Symptoms in Patients With Myotonic Dystrophy Type 1

Myotonic Dystrophy 1 | Excessive Daytime Sleepiness

United States, Canada
Syntrix Biosystems, Inc.
National Institute on Drug Abuse (NIDA); DF/Net Research

Completed

Omnitram Safety and Efficacy in the Treatment of Diabetic Neuropathy

Diabetic Neuropathies | Neuropathic Pain | Pain, Chronic

United States
University of Oxford
Novo Nordisk A/S

Recruiting

A Study of Cardiovascular Events iN Diabetes Plus (ASCEND PLUS)

Diabetes Mellitus, Type 2

United Kingdom
Fulcrum Therapeutics

Terminated

Losmapimod Safety and Efficacy in COVID-19 (LOSVID)

COVID-19

United States, Mexico, Brazil, Peru
EicOsis Human Health Inc.

Completed

Safety, Tolerability, Pharmacokinetics and Food Effects of Oral EC5026 in Healthy Subjects

Healthy Adults

United States
Vaxart

Completed

Phase 1 Placebo-controlled, Randomized Trial of an Adenoviral-vector Based Norovirus Vaccine

Norovirus Gastroenteritis

United States
Damanhour University

Completed

Ivabradine in Patients With Congestive Heart Failure

Congestive Heart Failure

Egypt
Estetra
Quotient Clinical

Completed

Study Conducted to Further Understand the Elimination Pathways, Metabolite Profile and PK Profile of 14C-estetrol

Menopause | Contraception

United Kingdom
Pantarhei Oncology B.V.

Completed

Evaluation of Safety and Efficacy of Estetrol in Healthy Men

Prostatic Neoplasms

Netherlands
Baylor Research Institute

Not yet recruiting

Neratinib in Combination With Ruxolitinib in Patients With mTNBC

Breast Cancer | Metastatic Triple-Negative Breast Carcinoma

United States
Vaxart

Completed

Dose-Ranging Trial of Safety & Immunogenicity of an Oral Adenoviral-Vector Based RSV Vaccine (VXA-RSV-f)

Respiratory Syncytial Virus (RSV)

United States
University of California, Los Angeles

Recruiting

Metformin Treatment in Progressive Multiple Sclerosis

Primary Progressive Multiple Sclerosis | Secondary Progressive Multiple Sclerosis

United States
Ocera Therapeutics, Inc.

Completed

OCR002-SP103 - Oral Immediate Release Study

Cirrhosis

United States
Cara Therapeutics, Inc.

Recruiting

A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States
Cara Therapeutics, Inc.

Recruiting

CR845-310302: A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States, Korea, Republic of, Australia, Bulgaria, Germany, Hungary, Italy, Poland, Romania, Spain, Argentina, Brazil, Mexico
University of Milan

Not yet recruiting

Carnosine Supplementation on Quantity/Quality of Oral Salivae. (PHoral)

Oral Diseases

Italy
The Mind Research Network

Terminated

Mechanisms of Lorcaserin for Smoking Cessation

Smoking Cessation | Tobacco Use Disorder

United States
Donesta Bioscience
SynteractHCR

Completed

E4Relief (Response to Estetrol in Life Improvement for MEnopausal-associated Hot Flushes)

Hot Flushes

Belgium
Sunshine Lake Pharma Co., Ltd.

Completed

The Tolerability and Pharmacokinetics Study of HEC110114 Tablets in Healthy Adult Subjects (HEC110114)

Chronic Hepatitis C

China
Mereo BioPharma
Syneos Health

Completed

A 12-week Study Treating Participants Who Have alpha1-antitrypsin-related COPD With Alvelestat (MPH966) or Placebo. (ASTRAEUS)

Emphysema | Alpha 1-Antitrypsin Deficiency | COPD

United Kingdom, Belgium, United States, Denmark, Canada, Sweden, Poland, Spain
Harmony Biosciences, LLC

Completed

A Phase 3 Study to Assess the Safety and Efficacy of Pitolisant in Adult Patients With Idiopathic Hypersomnia

Idiopathic Hypersomnia

United States
Cassava Sciences, Inc.
National Institute on Aging (NIA)

Completed

PTI-125 for Mild-to-moderate Alzheimer's Disease Patients

Alzheimer Disease

United States
GlaxoSmithKline

Completed

GSK189075, GW869682 Or Placebo In Type 2 Diabetic Patients

Diabetes Mellitus, Type 2 | Non-Insulin-Dependent Diabetes Mellitus

Germany, United States
Pierre Fabre Medicament
Biotrial

Active, not recruiting

Relative Bioavailability of Binimetinib 3 x 15 mg and 45 mg Formulations

Melanoma | Metastatic Melanoma | Unresectable Melanoma | BRAF V600 Mutation

France
Grupo Cooperativo de Hemopatías Malignas

Completed

Treatment of SARS Caused by COVID-19 With Ruxolitinib

COVID-19 | Severe Acute Respiratory Syndrome Coronavirus 2

Mexico
Azienda Ospedaliero, Universitaria Pisana

Unknown

Baricitinib Compared to Standard Therapy in Patients With COVID-19 (BARICIVID-19)

Covid-19 | SARS-CoV 2 | SARS Pneumonia

Italy
Estetra

Completed

Safety, Tolerability and Pharmacokinetics of Estetrol (E4) After Single and Multiple Oral Doses in Healthy Female Volunteers

Menopause | Contraception

Bulgaria
AgeneBio
National Institute on Aging (NIA)

Completed

Study of AGB101 in Mild Cognitive Impairment Due to Alzheimer's Disease (HOPE4MCI)

Mild Cognitive Impairment | Prodromal Alzheimer's Disease

United States, Canada
Yiling Pharmaceutical Inc.

Completed

A Single-dose Study to Investigate the Tolerance and Pharmacokinetics of Finamine Tablets in China

Parkinson Disease

China
Pfizer

Terminated

Efficacy, Safety and Tolerability of PF-06649751 in Parkinson's Disease Patients at Early Stage of the Disease

Parkinson Disease

United States, France, Israel, Germany
Azienda USL Toscana Nord Ovest
Azienda Ospedaliero, Universitaria Pisana; Azienda Ospedaliera Universitaria... and other collaborators

Unknown

Ruxolitinib for the Treatment of Acute Respiratory Distress Syndrome in Patients With COVID-19 Infection (RESPIRE)

Severe Acute Respiratory Syndrome Coronavirus 2
Charite University, Berlin, Germany
Bayer

Not yet recruiting

Study to Investigate Improvement in Physical Function in SF-36 With Vericiguat Compared With Placebo in Participants With Post-COVID-19 Syndrome

Post-COVID ME/CFS

Germany
Pierre Fabre Medicament
Biotrial

Completed

Bioequivalence Binimetinib 3 x 15 mg and 45 mg Formulations

Melanoma | Metastatic Melanoma | Unresectable Melanoma | BRAF V600 Mutation

France
Peking University
The First Affiliated Hospital with Nanjing Medical University; Xiangya Hospital... and other collaborators

Active, not recruiting

Ripretinib in Chinese Patients With Advanced GIST: a Real World Study

Gastrointestinal Stromal Tumors

China
Ain Shams University
Cairo University

Recruiting

Pharmacokinetics, Safety, Efficacy and Acceptability of Daclatasvir Plus Sofosbuvir in HCV-infected Children

HCV

Egypt

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