Search clinical trials for: Estradiol (E2)

Total 1081 results

University of Michigan
National Institute on Aging (NIA)

Completed

Early Menopause Hormone Treatment and Cognition (R21)

Menopausal Syndrome

United States
Bayer

Completed

Low-dose Hormone Therapy for Relief of Vasomotor Symptoms

Vasomotor Symptoms | Hot Flashes

United States
Organon and Co

Withdrawn

Efficacy and Safety of Oral NOMAC-E2 in Indian Women (P07057/MK-8175A-017)

Contraception
Organon and Co
IQVIA Inc.; OSTAtistics

Terminated

Contraceptive Efficacy and Safety of NOMAC-E2 Combined Oral Contraceptive

Contraception

United States
AbbVie

Completed

Safety and Efficacy in Premenopausal Women With Heavy Menstrual Bleeding (HMB) Associated With Uterine Fibroids (UF)

Uterine Fibroids | Heavy Uterine Bleeding
Alexandria University

Completed

Hormonal Monitoring and Progesterone Adjustment in Frozen Embryo Transfer Cycles

Female Infertility

Egypt
Myovant Sciences GmbH

Completed

LIBERTY 2: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Uterine Fibroid | Heavy Menstrual Bleeding

United States, Belgium, Czechia, South Africa, Chile, Brazil, Hungary, Poland
Organon and Co

Completed

A Dose-Finding Study to Evaluate Ovarian Function and Vaginal Bleeding in Next Generation Rings (P06109/MK-8175A/MK-8342B-012)

Contraception
Organon and Co
CRS Mannheim GmbH

Completed

A Trial to Assess the Pharmacokinetic Profile (e.g., Uptake, Distribution and Excretion of a Substance in the Body) of Nomegestrol Acetate (NOMAC), Estradiol (E2) and Estrone (E1) After Multiple and Single Dose Administration of the Combined Oral Contraception NOMAC-E2 (COMPLETED)(P05822)

Healthy
Massachusetts General Hospital
National Institutes of Health (NIH); National Institute on Aging (NIA)

Completed

Effect of Race on Gonadotropin Responses

Healthy | Premenopause

United States
Organon and Co

Completed

Effects on Hemostasis, Lipids, Carbohydrate Metabolism, Adrenal & Thyroid Function of the Combined Oral Contraceptive NOMAC-E2 Compared to a COC Containing LNG-EE (292004)(COMPLETED)(P05764)

Contraception
Bayer

Completed

Angeliq Regulatory Post Marketing Surveillance (Angeliq rPMS)

Osteoporosis, Postmenopausal | Postmenopausal Period

Korea, Republic of
Genexine, Inc.

Completed

Study to Evaluate Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of GX-E2 in Healthy Subjects (GX-E2-P1)

Healthy

Korea, Republic of
AbbVie

Completed

A Clinical Study to Evaluate the Safety and Efficacy of Elagolix in Participants With Moderate to Severe Endometriosis-Associated Pain

Endometriosis

United States, Canada, Puerto Rico
ART Fertility Clinics LLC

Recruiting

Optimal Timing of Euploid Day 6 Blastocyst Transfer in Frozen HRT Cycles, Day 6 or Day 7 of Progesterone Administration.

Infertility | Fertility Issues | Infertility, Female

United Arab Emirates
Akdeniz University

Completed

The Impact of Estrogen Administration Duration in Hormonally Prepared Frozen Embryo Transfer Cycles

Duration of Estrogen Administration

Turkey
Bayer

Completed

Julina Post-marketing Surveillance for Climacteric Symptoms in Japan (JULINA-CLIMA)

Osteoporosis, Postmenopausal

Japan
Bayer

Completed

Julina Post-marketing Surveillance for Postmenopausal Osteoporosis in Japan

Osteoporosis, Postmenopausal

Japan
Organon and Co

Completed

Bioequivalence of Nomegestrol Acetate (NOMAC) and Estradiol (E2) in Commercial Versus Phase 3 Pivotal Clinical Batches of NOMAC-E2 Tablets (P06328)

Healthy Postmenopausal Females
Myovant Sciences GmbH

Completed

SPIRIT 1: Efficacy and Safety Study of Relugolix in Women With Endometriosis-Associated Pain

Endometriosis Related Pain

United States, Spain, Hungary, Argentina, Belgium, Bulgaria, Canada, Czechia, Finland, Poland, Portugal, South Africa, Ukraine
Myovant Sciences GmbH

Completed

SPIRIT 2: Efficacy and Safety Study of Relugolix in Women With Endometriosis-Associated Pain

Endometriosis Related Pain

United States, Poland, Australia, Brazil, Chile, Czechia, Georgia, Italy, New Zealand, Romania, Sweden
Myovant Sciences GmbH

Completed

Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Uterine Fibroids | Uterine Leiomyoma

United States, Italy, Poland, Czechia, Hungary, South Africa, Brazil, Chile
Jeanne Drisko, MD, CNS, FACN
University of Kansas; Private Foundation through KU Endowment

Terminated

Bioidentical 'Natural' Hormone Evaluation in Early Menopause

Menopause

United States
Organon and Co

Terminated

Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring and Levonorgestrel-Ethinyl Estradiol Combined Oral Contraceptive in Adult Women at Risk for Pregnancy (MK-8342B-062)

Contraception

South Africa, Austria, Costa Rica, Denmark, Finland, Germany, Hungary, Italy, Mexico, Netherlands, Norway, Peru, Poland, Sweden
Bayer

Completed

Wellnara Post-marketing Surveillance in Japan (WELLNARA)

Osteoporosis, Postmenopausal

Japan
University Hospital, Toulouse

Completed

Effect of 17ß-estradiol on Inflammatory-immune Responses in Post-menopausal Women According to Administration Route

Postmenopausal

France
Yale University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Sex Hormones and Orthostatic Tolerance

Orthostatic Intolerance

United States
CytoCore, Inc.
University Hospitals Cleveland Medical Center

Completed

Adequacy and Efficacy of the e2TM Cervical Cell Collector Compared to Standard Spatula/CytoBrush Technique.

Colposcopy | Biopsy

United States
AbbVie

Completed

Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women (Replicate Study)

Uterine Fibroids | Heavy Menstrual Bleeding

United States, Canada
AbbVie

Completed

Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women

Uterine Fibroids | Heavy Menstrual Bleeding

United States, Canada, Puerto Rico
Boston Pharmaceuticals

Completed

Study to Determine the Relative Bioavailability, Single and Repeat Dose Pharmacokinetics, Safety and Tolerability of BOS172767 Enantiomers in Healthy Subjects

Healthy Participants

United Kingdom
AbbVie

Active, not recruiting

Long-Term Safety Study of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women

Uterine Fibroids | Heavy Menstrual Bleeding

United States, Puerto Rico
AbbVie (prior sponsor, Abbott)

Completed

Safety and Efficacy of Elagolix in Pre-Menopausal Women With Heavy Uterine Bleeding and Uterine Fibroids

Uterine Fibroids | Heavy Uterine Bleeding
National and Kapodistrian University of Athens

Terminated

Oestradiol Pre-treatment in an Ultrashort Flare GnRH Agonist/GnRH Antagonist Protocol in Poor Responders Undergoing IVF

Infertility

Greece
AbbVie

Terminated

A Study to Evaluate Safety and Efficacy of Elagolix in Participants With Endometriosis With Associated Moderate to Severe Pain

Endometriosis

United States
Maire Mac Bride
National Center for Advancing Translational Sciences (NCATS)

Terminated

A Trial to Evaluate the Efficacy of Low Dose Vaginal Estrogens in the Treatment of Atrophic Vaginitis

Atrophic Vaginitis

United States
Health Decisions
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

A Dose-finding Study to Evaluate the Effect of a Contraceptive Vaginal Ring, Releasing Nestorone® and Estradiol, on Cycle Control, Ovulation Inhibition, and Pharmacokinetics in Normal Cycling Women

Suppression of Ovulation

United States
Bayer
University of California, San Francisco; Laboratorium für Klinische Forschung; Diagnostic Cytology Laboratory

Completed

Endometrial Safety Study

Postmenopause

Mexico, United States, Italy, Denmark, Austria, Argentina, Brazil, Russian Federation
Myovant Sciences GmbH

Completed

LIBERTY 1: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Uterine Fibroid | Heavy Menstrual Bleeding

United States, Italy, Poland, Brazil, South Africa, United Kingdom
University Medical Centre Maribor

Not yet recruiting

Propess Versus Prostin for Induction of Labour in Women With Term PROM (PESTIBOR)

Induction of Labour | Premature Rupture of Membranes at Term
London North West Healthcare NHS Trust

Terminated

Vaginal Estrogen for the Treatment of Faecal Incontinence in Women

Fecal Incontinence

United Kingdom
Population Council

Completed

A Phase 2, Dose-finding, Cross-over Study to Evaluate the Effect of a NES/E2 Transdermal Gel Delivery on Ovulation Suppression in Normal Ovulating Women

Ovulation

Dominican Republic, Chile, United States
Rennes University Hospital

Unknown

Improved Medically Assisted Procreation Monitoring (NGAMP)

Infertility

France
Organon and Co

Completed

Thorough QT/QTc Study of Multiple Oral Doses of NOMAC-E2 (Org 10486 0 + Org 2317) in Healthy Women (Study 292011)(P05802)

Contraception
Organon and Co

Terminated

Study of the Contraceptive Efficacy and Safety of a NOMAC-E2 Combined Oral Contraceptive (COC)(P06448)

Contraception
Shanghai First Maternity and Infant Hospital

Unknown

The Use of High-energy Digestible Food in Women Undergoing Caesarean Section

Caesarean Section

China
University of Colorado, Denver

Completed

Effects of Ovarian Hormone Suppression on Vascular and Cognitive Function

Cognitive Impairment | Menopause | Endothelial Dysfunction | Vascular Stiffness | Estrogen Deficiency

United States
Health Decisions
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Unknown

Study of Efficacy, Cycle Control, and Safety of a NES-E2 Contraceptive Vaginal Ring

Female Contraception | Healthy Women

United States
University of Pittsburgh
University of Zimbabwe

Completed

HIV-Target Cell Response in Women Initiating Various Contraceptive Methods in High HIV-Incidence Areas: Zim CHIC (Zim CHIC)

HIV | Contraception | Microbiota | Immune Cells (Mucosal and Systemic)

Zimbabwe
Johnson & Johnson Vision Care, Inc.

Completed

One Month Daily Wear Clinical Evaluation of New Prototype Contact Lenses in Habitual and Neophyte Contact Lens Wearers

Visual Correction

India

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