Search clinical trials for: Excitatory Amino Acid Agonists

Total 10166 results

University Hospital, Caen

Completed

Excitotoxicity Markers and the Clinical-radiological Progression After a Demyelinating Event: a Prospective Pilot Study (EXCEED)

Multiple Sclerosis
Hospital de Clinicas de Porto Alegre

Unknown

Therapeutic Efficacy of Oral L-Ornithine-L-Aspartate on Minimal Encephalopathy (PORTOALEGRE)

Hepatic Encephalopathy

Brazil
Air Force Military Medical University, China

Completed

The Effectiveness of L-ornithine-L-aspartate (LOLA) on Plasma Ammonia in Cirrhotic Patients After TIPS

Decompensated Cirrhosis | Portal Hypertension | Bleeding Varices | Refractory Ascites

China
All India Institute of Medical Sciences, New Delhi

Unknown

Therapeutic Efficacy of L-Ornithine L-Aspartate Infusion in Patients With Acute Liver Failure

Acute Liver Failure

India
Aga Khan University

Completed

Efficacy of L-Ornithine-L-Aspartate in Cirrhotics With Hepatic Encephalopathy

Hepatic Encephalopathy

Pakistan
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Efficacy of L-ornithine L-aspartate and Therapeutic Plasma Exchange Versus Plasma Exchange Alone in Lowering Ammonia and Improving Outcomes in Pediatric Acute Liver Failure.

Liver Failure, Acute

India
Imperial College London
University of London; Royal College of Physicians; Paddington Charitable Estates...

Completed

Brain Imaging in Patients With Chronic Liver Disease and Functional Impairment.

Hepatic Encephalopathy | Cirrhosis

United Kingdom
New York State Psychiatric Institute

Completed

Glutamatergic Modulation of Motivation Enhancement: A Pilot Feasibility Trial

Cocaine Use Disorders

United States
Medical University of Graz
CBmed Ges.m.b.H.

Recruiting

Effect of L-ornithine-L-aspertate (LOLA) on the Gut Microbiome (LOLAbiome)

Cirrhosis

Austria
State University of New York at Buffalo

Enrolling by invitation

Repurposing Lithium for Parkinson's Disease

Parkinson's Disease

United States
Centro Regional para el Estudio de las Enfermedades...
MERZ PHARMA

Completed

Efficacy of L-Ornithine L-Aspartate in Acute Hepatic Encephalopathy.

Hepatic Encephalopathy

Mexico
Dayanand Medical College and Hospital

Completed

L-ornithine L-aspartate in Overt Hepatic Encephalopathy (HEAL)

Hepatic Encephalopathy | Cirrhosis of Liver

India
Ain Shams University

Recruiting

Efficacy of L-Ornithine L-Aspartate (LOLA) as an Adjunct to Branched Chain Amino Acids (BCAA) Enriched Solutions on Clinical Outcomes in ICU Patients With Hepatic Encephalopathy

Hepatic Encephalopathy

Egypt
Sanofi

Terminated

Effect of Chronic Supplementation of L-arginine in the Muscular Performance

Muscular Fatigue

Brazil
Mahidol University

Completed

Efficacy of Combined Oral L-ornithine-L-aspartate and Lactulose in Patients With Hepatic Encephalopathy

Hepatic Encephalopathy

Thailand
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Talampanel for Amyotrophic Lateral Sclerosis (ALS) (ALS)

ALS

United States, Netherlands, Canada, Italy, Spain, Belgium, France, Germany, Hungary, Israel
National Institute of Mental Health (NIMH)

Completed

Clinical Trial of Felbamate for Treatment-Resistant Bipolar Depression

Bipolar Disorder

United States
Northwestern University

Completed

Does a Single Intravenous Dose of Ketamine Reduce the Need for Supplemental Opioids in Post-Cesarean Section Patients?

Ketamine Adverse Reaction | Effects of; Anesthesia, Spinal and Epidural, in Pregnancy | Complication of Labor and/or Delivery

United States
BrainCells Inc.

Completed

A Multiple Ascending Dose Study of BCI-838 in Healthy Volunteers

Healthy

Netherlands
Emory University

Completed

Effects of Riluzole on CNS Glutamate and Fatigue in Breast Cancer Survivors With High Inflammation

Inflammation | Fatigue

United States
King's College London
South London and Maudsley NHS Foundation Trust

Recruiting

The Role of Glutamatergic Function in the Pathophysiology of Treatment-resistant Schizophrenia (RESTORE)

Treatment-resistant Schizophrenia | Healthy Controls | Treatment-responsive Schizophrenia

United Kingdom
National Institute of Mental Health (NIMH)

Completed

Riluzole to Treat Child and Adolescent Obsessive-Compulsive Disorder With or Without Autism Spectrum Disorders

Obsessive-Compulsive Disorder | Autism Spectrum Disorder | Autism | Asperger Disorder | Developmental Disorder

United States
Jinnah Postgraduate Medical Centre

Not yet recruiting

Efficacy of L-Ornithine L-Aspartate and Polyethylene Glycol in Cirrhotic Patients With Overt Hepatic Encephalopathy

Hepatic Encephalopathy Stage 2 | Hepatic Encephalopathy Stage 3 | Hepatic Encephalopathy Stage 4

Pakistan
National Institute of Mental Health (NIMH)

Completed

Riluzole to Treat Major Depression

Depression

United States
Mclean Hospital

Completed

Riluzole in the Treatment of Bipolar Depression

Bipolar Depression

United States
Yale University

Completed

Efficacy and Tolerability of Riluzole in Treatment Resistant Depression

Depression

United States
PNA Center for Neurological Research
Eisai Inc.

Unknown

Fycompa in Subjects With Small Fiber Neuropathy (SFN)

Neuropathy, Small Fiber

United States
National Institute of Neurological Disorders and...

Completed

Treatment of Parkinson's Disease With Eliprodil

Parkinson Disease | Movement Disorders

United States
Hospital General de Mexico

Completed

Lactulose, L-ornithine L-aspartate, or Rifaximin Versus Placebo for Preventing Hepatic Encephalopathy in Variceal Bleeding

Hepatic Encephalopathy

Mexico
National Institute of Mental Health (NIMH)

Terminated

Riluzole to Treat Depression in Bipolar Disorder

Bipolar Disorder

United States
Yale University

Completed

Functional Neuroimaging of Alcoholism Vulnerability (PIT) (CTNA)

Healthy

United States
Yale University
National Institute of Mental Health (NIMH)

Completed

Riluzole Augmentation in Treatment-refractory Obsessive-compulsive Disorder

Obsessive-compulsive Disorder | Ocd

United States
Chinese Medical Association

Recruiting

Elevated Initial APRI Value Was Associated With SALD

Liver Dysfunction | Sepsis-associated Liver Dysfunction

China
Xinhua Hospital, Shanghai Jiao Tong University...
Beijing YouAn Hospital; Beijing Ditan Hospital; First Affiliated Hospital, Sun... and other collaborators

Recruiting

The Efficacy and Safety of Ornithine Aspartic Acid Granules in NAFLD Against Silymarin Capsules

Non-alcoholic Fatty Liver Disease

China
National Taiwan University Hospital

Unknown

Memantine add-on for Cognitive and Negative Symptoms of Schizophrenia

Schizophrenia

Taiwan
National Institute of Neurological Disorders and...

Completed

Dextromethorphan for the Treatment of Parkinson's Disease and Similar Conditions of the Nervous System

Parkinson's Disease | Neurodegenerative Disease

United States
Johns Hopkins University
National Institute of Mental Health (NIMH)

Completed

Developing New Treatments for Tourette Syndrome: Therapeutic Trials With Modulators of Glutamatergic Neurotransmission

Tourette Syndrome

United States
Assiut University

Completed

Effect of Memantine on Cognitive Impairment in Patients With Epilepsy

Epilepsy

Egypt
University Hospital, Lille

Completed

Study of Memantine for Gait Disorders And Attention Deficit In Parkinson's Disease (FOGG-I)

Parkinson's Disease | Gait Disorders, Neurologic

France
King's College London

Unknown

Memantine and Down's Syndrome

Dementia | Learning Disabilities | Down's Syndrome

United Kingdom
Population Health Research Institute

Terminated

Preventing pAIn With NMDA Antagonists - Steroids in Thoracoscopic lObectomy Procedures (PAIN-STOP) Pilot Trial (PAIN-STOP)

Pain, Postoperative

United States, Canada
Assiut University

Recruiting

Memantine Hydrochloride for Treatment of Cognitive Dysfunction Due to Traumatic Brain Injury

Treatment of Posttraumatic Cognitive Dysfunction

Egypt
National Institute of Mental Health (NIMH)

Completed

Clinical Trial of Memantine for Major Depression

Depression

United States
University Medicine Greifswald

Completed

EUROPAC-2 - Pain Treatment of Hereditary and Idiopathic Pancreatitis

Pancreatitis
Washington University School of Medicine
National Alliance for Research on Schizophrenia and Depression

Completed

Prevention of N-methyl-D-aspartate (NMDA) Antagonist-induced Psychosis in Kids

Psychoses, Substance-Induced

United States
BrainCells Inc.

Completed

A Study of BCI-838 and Several BCI-632 Prodrugs in Healthy Volunteers

Healthy

Netherlands
University of Washington
Forest Laboratories

Unknown

Memantine for Post-Operative Pain Control

Pain, Post-operative

United States
AB Science

Recruiting

Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients

Amyotrophic Lateral Sclerosis

France, Spain, United States, Sweden, Denmark, Portugal, Italy, Israel, Germany, Norway, Poland, Russian Federation, Slovenia, Ukraine, Greece, Belgium, Serbia
King Abdullah International Medical Research Center

Unknown

Effect of N-methyl D-aspartate (NMDA) Receptor Antagonist Dextromethorphan on Opiods Analgesia and Tolerance in Pediatric Intensive Care Unit Patients

Pain | Opioid Tolerance | Analgesia Tolerance

Saudi Arabia
James Murrough

Completed

Ketamine For Suicidal Ideation

Suicidal Ideation

United States

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