Search clinical trials for: Ezetrol (Ezetimibe)

Total 458 results

University Medicine Greifswald

Completed

Pharmacokinetic and Pharmacodynamic Interactions Between the Cholesterol-lowering Ezetimibe and the Non-nucleoside Reverse Transcriptase Inhibitor Efavirenz During Chronic Treatment in Healthy Volunteers With Reference to Intestinal Expression of CYP3A4, UGT1A1, ABCB1 and ABCC2

Pharmacokinetics | Pharmacodynamics | Drug Interactions | Intestinal Transporter Expression

Germany
NVP Healthcare

Completed

to Investigate the Pharmacokinetic Interactions and Safety Between Rosuvastatin and Ezetimibe in Healthy Male Volunteers (NVP-1205)

Healthy
Cao Yu

Recruiting

Bioequivalence of Ezetimibe Tablets in Healthy Subjects

Therapeutic Equivalency

China
The Affiliated Hospital of Qingdao University

Completed

Bioavailability and Bioequivalence of Ezetimibe Tablets in Healthy Subjects

Hyperlipidemias

China
University Medicine Greifswald

Completed

Pharmacokinetic Drug Interaction Between Ezetimibe and Tacrolimus After Single Dose Administration in Healthy Subjects

Hypercholesterolemia | Pharmacokinetics | Immunosuppression | Drug Interactions

Germany
Chong Kun Dang Pharmaceutical

Completed

CKD-391 DDI : Atorvastatin and Ezetimibe in Healthy Volunteers

Healthy

Korea, Republic of
Medical University of Graz

Completed

Fluvastatin 80 mg Ret. vs Combination With Ezetimibe 10 mg in Patients With High Cardiovascular Risk

Hypercholesterolemia

Austria
Korea University

Withdrawn

Effects on Atherosclerosis Regression of Ezetimibe or Ezetimibe Plus Simvastatin; Evaluated by Fluorodeoxyglucose Positron Emission Tomography (FDG-PET)

Atherosclerosis

Korea, Republic of
JW Pharmaceutical

Completed

To Evaluate the Efficacy and Safety in Patients With Primary Hypercholesterolemia

Primary Hypercholesterolemia

Korea, Republic of
University Hospital Freiburg
Essex Pharma GmbH

Completed

Effect of Ezetimibe or Simvastatin or Both on Low Densitiy Lipoprotein -Subfractions in Patients With Type 2 Diabetes (EZE)

Hypercholesterolemia | Diabetes Mellitus Type 2

Germany
University Medicine Greifswald

Completed

Pharmacokinetic Drug Interaction Between Ezetimibe and Sirolimus After Single Dose Administration in Healthy Subjects

Hypercholesterolemia | Pharmacokinetics | Immunosuppression | Drug Interactions

Germany
University of California, San Diego

Completed

Ezetimibe Versus Placebo in the Treatment of Non-alcoholic Steatohepatitis

Non Alcoholic Steatohepatitis

United States
University of Oxford
National Health and Medical Research Council, Australia; Merck Sharp & Dohme... and other collaborators

Completed

Study of Heart and Renal Protection (SHARP)

Kidney Disease, Chronic

United Kingdom
Shanghai Jiao Tong University School of Medicine

Unknown

Atorvastatin Plus Ezetimibe on Coronary Plaque Progression (AEPP)

Coronary Artery Disease

China
Odense University Hospital

Completed

Ezetimibe In Addition To Atorvastatin Therapy On The Plaque Composition In Patients With Acute Myocardial Infarction. (OCTIVUS)

ST-Segment Elevation Myocardial Infarction

Denmark
Xijing Hospital

Unknown

Ezetimibe and Atorvastatin Therapy on TCFA

Coronary Artery Disease

China
Organon and Co

Completed

Observational Study of Approaches to Lipid-Lowering Therapy in Russian Patients With Coronary Heart Disease <<Treat to Goal>> (Study P05464)

Hypercholesterolemia | Coronary Heart Disease
Laval University

Completed

Effects of Selective Inhibition of Cholesterol Absorption With Ezetimibe on Intestinal Cholesterol Homeostasis in Dyslipidemic Men With Insulin-resistance - a Pilot Study (EZEmRNA)

Metabolic Syndrome X

Canada
NVP Healthcare

Completed

Compare the Pharmacokinetics of NVP-1205 and Coadministration of Rosuvastatin and Ezetimibe (NVP-1205)

Dyslipidemia

Korea, Republic of
Abbott

Completed

Safety and Efficacy Study Comparing ABT-335 Coadministered With Atorvastatin and Ezetimibe to Atorvastatin Coadministered With Ezetimibe in Subjects With Multiple Abnormal Lipid (Fat) Levels in the Blood

Dyslipidemias | Coronary Heart Disease | Mixed Dyslipidemia | Combined (Atherogenic) Dyslipidemia

United States
Organon and Co

Completed

Effect Of Ezetimibe Coadministration With Simvastatin In A Middle Eastern Population: A Prospective, Multicentre, Randomized, Double-Blind, Placebo-Controlled Trial (0653-151)

Hypercholesterolemia
Karolinska Institutet
Danderyd Hospital

Completed

Platelet Function in Diabetic Patients With and Without Renal Impairment, and the Effects of Lipid Lowering Treatment (PLAUDIT)

Diabetes Mellitus | Impaired Renal Function

Sweden
Laboratorios Silanes S.A. de C.V.

Completed

Study of no Pharmacokinetic Interaction Between Rosuvastatin 20mg and Ezetimibe10mg, Fixed Dose vs Individual Components

Healthy

Mexico
Daewon Pharmaceutical Co., Ltd.

Completed

Clinical Trial to Evaluate the Efficacy and Safety of DW1125 and DW1125A

Hypercholesterolemia, Dyslipidemia

Korea, Republic of
LMC Diabetes & Endocrinology Ltd.
Bausch Health Americas, Inc.

Completed

Randomized Trial Comparing Colesevelam vs. Ezetimibe (GOAL-RCT)

Type 2 Diabetes Mellitus

Canada
Merck Sharp & Dohme LLC

Completed

Ezetrol Post-Marketing Study

Hyperlipidemia
University Clinical Centre of Republic of Srpska

Recruiting

Low-density Lipoprotein Cholesterol Reduction With State-of-the-art Therapy in Secondary Prevention and Major Cardiovascular Adverse Events: Republic of Srpska Registry (RS-ACS)

Dyslipidemias | Acute Coronary Syndrome

Bosnia and Herzegovina
University of British Columbia
Merck Frosst-Schering Pharma, G.P.

Completed

Addition of Ezetimibe (Ezetrol®) to Ongoing Therapy With Rosuvastatin (Crestor®) in HIV Positive Patients Not Reaching Cholesterol Targets

HIV Infections | Hypercholesterolemia

Canada
Organon and Co

Completed

Study To Assess The Efficacy Of A Cholesterol Lowering Drug On Top Of Statins In Patients After Myocardial Infarction (MI)(0653A-150)

Cardiovascular Disorder
Regeneron Pharmaceuticals
Sanofi

Completed

Study of Alirocumab (REGN727/SAR236553) added-on to Rosuvastatin Versus Other Lipid Modifying Treatments (LMT) (ODYSSEY OPTIONS II)

Hypercholesterolemia

United States, France, Italy, Germany, Spain, Canada, United Kingdom, Australia, Mexico
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Active, not recruiting

Investigating the Lowest Threshold of Vascular Benefits From LDL Cholesterol Lowering in Patients With Stable CV Disease (INTENSITY-HIGH)

Cardiovascular Diseases | Atherosclerosis

United Kingdom
Queen's University

Completed

Atorvastatin Versus Ezetimibe and Fenofibrate as a Lipid-lowering Strategy

Dyslipidemia | Vascular Disease

Canada
Regeneron Pharmaceuticals
Sanofi

Completed

Study of the Efficacy and Safety of Alirocumab (REGN727/SAR236553) in Combination With Other Lipid-modifying Treatment (LMT) (ODYSSEY OPTIONS I)

Hypercholesterolemia

United States, France, Italy, Germany, Spain, Mexico, Canada, United Kingdom, Australia
Pantarhei Bioscience

Completed

Study to Evaluate 3 Dosages of Estetrol After 28 Days Administration in Healthy Postmenopausal Women

Healthy

Netherlands
Yonsei University
dotter

Recruiting

Comparative Study of Rosuvastatin/Ezetimib 20/10 mg and Atovastatin/Ezetimib 40/10 mg (TOLERANT Trial)

Coronary Artery Disease | Dyslipidemias

Korea, Republic of
Organon and Co

Completed

Co-administration Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-802)(COMPLETED)

Coronary Disease | Hypercholesterolemia
Organon and Co

Completed

An Investigational Drug Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-804)(COMPLETED)

Coronary Disease | Hypercholesterolemia
Organon and Co

Completed

Co-administration Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-803)

Coronary Disease | Hypercholesterolemia
Organon and Co

Completed

Investigational Drug Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-801)

Coronary Disease | Hypercholesterolemia
Estetra
Quotient Clinical

Completed

Study Conducted to Further Understand the Elimination Pathways, Metabolite Profile and PK Profile of 14C-estetrol

Menopause | Contraception

United Kingdom
Pantarhei Oncology B.V.

Completed

Evaluation of Safety and Efficacy of Estetrol in Healthy Men

Prostatic Neoplasms

Netherlands
Bronx VA Medical Center

Completed

Evaluation of LDL Cholesterol in Patients Switched From 10 to 5 Milligrams of Zetia (Ezetimibe)

Hypercholesterolemia

United States
Karo Bio AB

Completed

LDL-Cholesterol Lowering Effect of KB2115 as Add on to Ezetimibe

Hypercholesterolemia

Sweden
Kaleida Health

Unknown

To Study the Effect of Vytorin on Intracellular Lipid and Inflammation in Obese Subjects

Inflammation

United States
GlaxoSmithKline

Completed

Acotral® Versus Zetia® Ezetimibe Bioequivalance Study.

Hypercholesterolaemia

India
Peking Union Medical College Hospital

Unknown

Efficacy and Safety of Simvastatin-ezetimibe Combination Therapy Among Patients With SLE

Atherosclerosis

China
NewAmsterdam Pharma

Completed

Study to Evaluate the Effect of Obicetrapib in Combination With Ezetimibe as an Adjunct to HIS Therapy (ROSE2)

Dyslipidemias | Hypercholesterolemia | High Cholesterol

United States
NewAmsterdam Pharma

Recruiting

Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies (TANDEM)

Dyslipidemias | Hypercholesterolemia | Familial Hypercholesterolemia | High Cholesterol | ASCVD

United States
Organon and Co

Completed

A Study of MK0653A (Ezetimibe (+) Simvastatin) in Patients With Hypercholesterolemia (0653A-038)

Hypercholesterolemia
Donesta Bioscience
SynteractHCR

Completed

E4Relief (Response to Estetrol in Life Improvement for MEnopausal-associated Hot Flushes)

Hot Flushes

Belgium

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