Search clinical trials for: first-line chemotherapy

Total 8099 results

Peking University People's Hospital
Peking University Shougang Hospital

Completed

Clinical Evaluation of Neoadjuvant Chemotherapy for Primary Malignant Sarcomas That Originate in Bone (CESOFB-00)

Prognosis | Clinical Response | Histopathological Response

China
National Cancer Institute, Naples

Active, not recruiting

PET/CT Scan as a Tool to Rationalize the Treatment of Patients With Advanced ColoRectal Cancer Undergoing First-line Medical Treatment (PETRA2 - CRC)

Colorectal Cancer Stage IV

Italy
Novartis Pharmaceuticals

Active, not recruiting

A Non-interventional Study for Women With HR-positive, HER2-negative Locally Advanced or Metastatic Breast Cancer to Evaluate the Real-world Effectiveness of Treatment Algorithms Beginning With Ribociclib + AI/FUL, or With Endocrine Therapy or Chemotherapy as First Line Treatment (RIBANNA)

Breast Cancer

Germany
Hebei Tumor Hospital

Unknown

Safety and Efficacy of Ginsenoside Rg3 in Combination With First-line Chemotherapy in Advanced Gastric Cancer

Self Efficacy

China
Regina Elena Cancer Institute
Fondazione Policlinico Universitario Agostino Gemelli IRCCS; University of... and other collaborators

Active, not recruiting

Prospective Validation of a DNA Damage Repair-Hippo Pathway Signature in Patients With Advanced Gastric Cancer

Gastric Cancer | DNA Damage

Italy
French Innovative Leukemia Organisation
AbbVie; AstraZeneca; BeiGene; Janssen-Cilag Ltd.

Recruiting

French Observational Study of Patients With Chronic Lymphocytic Leukemia Or Small Lymphocytic Lymphoma in Real-World Settings (FOLLOW)

CLL/SLL

France
Lei Li

Completed

First-line Chemotherapy for Recurrent Cervical Cancer

Chemotherapy | Recurrent Cervical Carcinoma | Apatinib | Targeted Therapy | Persistent Advanced Cervical Carcinoma | Vascular Endothelial Growth Factor 2 Inhibitor

China
Joint Academy
Lund University; The Swedish Osteoarthritis Registry

Recruiting

Can Digitally Delivered First-line Osteoarthritis Treatment Improve Equal Access to Care (Access)

Osteoarthritis | First-line Treatment | Health Services Accessibility

Sweden
Shu-Zhong Cui
Guangdong Provincial Hospital of Traditional Chinese Medicine; Chinese PLA... and other collaborators

Unknown

Efficacy of HIPEC Combined With Systemic Chemotherapy and CRS on Peritoneal Metastases From Gastric Cancer

Gastric Cancer | Peritoneal Carcinomatosis

China
Genentech, Inc.

Completed

A Study of Bevacizumab in Combination With First- or Second-Line Therapy in Subjects With Treated Brain Metastases Due to Non-Squamous NSCLC (PASSPORT)

Brain Neoplasms | Non-Small Cell Lung Cancer
Rennes University Hospital
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

Completed

Hed-O-Shift: Hedonic and Neurocognitive Processes in Relation to Dietary Habits and Weight Status (Hed-O-Shift)

Neurocognitive Correlates of Eating Habits

France
CHU de Reims

Unknown

Clinical and Radiological Impact of Tibial Cutting Int Total Knee Arthroplasty, Accelerated Navigation Versus Extramedullary Targeting

Gonarthrosis

France
Zhejiang Cancer Hospital

Not yet recruiting

Durvalumab Combined With Chemotherapy and Stereotactic Body Radiotherapy (SBRT) in Patients With Oligometastatic Non-small Cell Lung Cancer (NSCLC)

Carcinoma, Non-Small-Cell Lung
Medical College of Wisconsin

Recruiting

Pancreatic Cancer Adaptive Neoadjuvant Chemotherapy Trial (PANC)

Pancreatic Cancer

United States
Guang'anmen Hospital of China Academy of Chinese...

Recruiting

Survival Benefit of Compound Kushen Injection in the Treatment of Advanced Colorectal Cancer

Advanced Colorectal Carcinoma

China
Henan Cancer Hospital

Recruiting

A Dose Exploration Study of Almonertinib for EGFRm NSCLC Patients With Brain/Leptomeningeal Metastasis (ARTISTRY)

NSCLC | Brain Metastases | Leptomeningeal Metastasis

China
Menoufia University

Completed

Radiotherapy to the Primary in Metastatic Non-small Cell Lung Cancer Patients

Radiation Therapy | Non-Small Cell Carcinoma of Lung, TNM Stage 4

Egypt
Microvention-Terumo, Inc.

Recruiting

REal-World Analyses of Stroke - Thrombus Occlusion REtrieval ("RESTORE")

Stroke | Acute Ischemic Stroke | Ischemic | Vessel Occlusion

United States
Hebei Tumor Hospital

Unknown

Pilot Study of Zoledronic Acid in Combination With First-line Chemotherapy in Aged Patients With Lung Cancer

Lung Cancer

China
Université de Sherbrooke

Unknown

Early Evaluation of the Response of Large B Cell Non Hodgkin's Lymphoma to Chemotherapy by PET/CT

Lymphoma, Large-Cell

Canada
Hoffmann-La Roche

Completed

A Study of MabThera (Rituximab) Plus Standard Chemotherapy in Patients With Previously Untreated Mantle Cell Lymphoma.

Mantle Cell Lymphoma

Hungary
Chinese PLA General Hospital

Unknown

Temozolomide as Maintenance Therapy Following Induction Chemotherapy in Extensive Stage Small Cell Lung Cancer

Extensive-stage Small Cell Lung Cancer

China
Joint Academy
Lund University

Completed

Change in Patient Reported Outcomes and Wish for Joint Surgery

Osteoarthritis, Knee and Hip

Sweden
University Hospital, Lille
Federation Francophone de Cancerologie Digestive; UNICANCER; Federation of Research...

Recruiting

Evaluation of Surgery Versus Primary Chemotherapy in Resectable Signet Ring Cell Gastric Adenocarcinoma (ADCI002)

Signet Ring Cell Gastric Adenocarcinoma

France
Mark Vincent
AstraZeneca

Recruiting

Osimertinib Then Chemotherapy in EGFR-mutated Lung Cancer With Osimertinib Third-line Rechallenge (OCELOT)

Non-Small Cell Lung Cancer

Canada
University Hospital, Angers
Vitaflo International, Ltd

Recruiting

Ketogenic Diet for Patients Receiving First Line Treatment for Metastatic Renal Cell Carcinoma (CETOREIN)

Metastatic Renal Cancer

France
Shanghai Gynecologic Oncology Group
Zhejiang Cancer Hospital; Sun Yat-sen University; Fudan University; Shanghai Zhongshan...

Active, not recruiting

Surgery or Chemotherapy in Recurrent Ovarian Cancer (SOC 1 Trial)?

Fallopian Tube Carcinoma | Ovarian Epithelial Cancer Recurrent | Primary Peritoneal Carcinoma

China
Fudan University

Not yet recruiting

Envafolimab Combined With Recombinant Human Endostatin and First-line Chemotherapy Treat of Advanced Mucosal Melanoma

Advanced Mucosal Melanoma
Tuen Mun Hospital

Unknown

Change in Body Weight During Treatment of Advanced Colorectal Cancer

Weight Loss | Chemotherapy Effect | Prognosis | Cancer, Colorectal

Hong Kong
Karolinska Institutet

Completed

Feasibility of Uninterrupted Infant Respiratory Support Treatment (FUIRST)

Respiratory Distress Syndrome, Newborn | Infant, Newborn | Respiratory Insufficiency Syndrome of Newborn

Sweden
National Development and Research Institutes, Inc.
The University of Texas Health Science Center, Houston

Completed

The First Twenty (TF20) for Volunteer Firefighters in a Clinic Based Setting

Obesity

United States
Institut fur Diabetesforschung, Munich, Germany

Unknown

BABYDIET-Study - Primary Prevention of Type 1 Diabetes in Relatives at Increased Genetic Risk

Type 1 Diabetes

Germany
Centre Oscar Lambret
University Hospital, Lille

Terminated

Correlation Between Tissue and Plasmatic EGFR in CBNPC With EGFR Mutation or Predictive Factor of EGFR Mutation (CONCORDE)

Nsclc

France
Hunan Province Tumor Hospital

Completed

Severe Adverse Events Biomarkers Investigation on Extensive Stage Small Cell Lung Cancer

Extensive Stage Small Cell Lung Cancer

China
Sun Yat-sen University

Not yet recruiting

Study to Evaluate the Safety and Efficacy of Serplulimab Plus Bevacizumab and Chemotherapy in NSCLC Patients With Brain Metastases (SUPER BRAIN)

Bevacizumab | Brain Metastases | Immunotherapy | Non-small Cell Lung Cancer Stage II

China
King Faisal Specialist Hospital & Research Center

Completed

First-Line Bevacizumab and Chemotherapy in Metastatic Cancer of the Colon or Rectum - International Study

Rectal Neoplasms | Colonic Neoplasms
Grupo Argentino de Tratamiento de la Leucemia Aguda

Recruiting

PET Adapted Treatment of Patients With Limited Stage DLBCL and no Risk Factors

Lymphoma, Non-Hodgkin's, Adult

Argentina
Australasian Gastro-Intestinal Trials Group
Cancer Council Victoria; Walter and Eliza Hall Institute of Medical Research

Recruiting

RESOLUTE Trial Aims to Investigate the Value of Adding Local Ablative Treatment to Standard Systemic Treatment for Unresectable Oligometastatic Colorectal Cancer (RESOLUTE)

Colorectal Cancer | Oligometastatic Disease

Australia
University of Liverpool
Infectious Diseases Institute, Makerere University College of Health Sciences

Recruiting

Pharmacokinetics of Drugs Used to Treat Drug Sensitive Tuberculosis in Breastfeeding Mother-infant Pairs (MILK TB)

Tuberculosis | Breastfeeding | Tuberculosis Active

Uganda
Grupo Argentino de Tratamiento de la Leucemia Aguda

Recruiting

RWE of 1st Line Treatment in Adults With AML From 18 to 70 Years Old.

Acute Myeloid Leukemia, Adult

Argentina
Hunan Province Tumor Hospital

Completed

Efficacy Biomarker Investigation on Extensive Stage Small Cell Lung Cancer

Extensive Stage Small Cell Lung Cancer

China
Hunan Province Tumor Hospital

Completed

Tumor Microenvironment Surveillance on Simultaneous Liver Metastases Extensive Stage Small Cell Lung Cancer

Extensive Stage Small Cell Lung Cancer

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Minimally Invasive Surgery After Neoadjuvant Chemotherapy for the Treatment of Stage IIIC-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer, LANCE Trial

Ovarian Endometrioid Adenocarcinoma | Ovarian Clear Cell Adenocarcinoma | Fallopian Tube Transitional Cell Carcinoma | Ovarian Transitional Cell Carcinoma | Fallopian Tube Clear Cell Adenocarcinoma | Ovarian Serous Adenocarcinoma | Primary Peritoneal Serous Adenocarcinoma | Primary Peritoneal Clear... and other conditions

United States
University College Cork

Completed

Short-term Topical Application to Prevent Atopic Dermatitis (STOP AD)

Eczema | Food Allergy | Eczema, Infantile | Eczema Atopic Dermatitis

Ireland
Fujian Cancer Hospital

Recruiting

HRQOL in Locally Advanced Thyroid Carcinoma (LATCQOL)

Thyroid Cancer | Health Related Quality of Life | Tyrosine Kinase Inhibitor

China
Pfizer

Not yet recruiting

A Study to Learn About the Effect of Avelumab First-Line Maintenance in Canadian People With Advanced Bladder Cancer

Urinary Bladder Neoplasms | Bladder Cancer | Urothelial Carcinoma | Bladder Tumors

Canada
Case Comprehensive Cancer Center

Recruiting

Natalizumab in Recurrent, Refractory or Progressive Pulmonary Metastatic Osteosarcoma

Pulmonary Metastatic Osteosarcoma (pOS)

United States
Biogen

Completed

A Study to Evaluate Efficacy, Safety, and Tolerability of EID of Natalizumab (BG00002) in Participants With RRMS Switching From Treatment With Natalizumab SID in Relation to Continued SID Treatment- Followed by Extension Study Comprising SC and IV Natalizumab Administration

Multiple Sclerosis, Relapsing-Remitting

United States, Spain, Canada, Australia, Germany, Italy, United Kingdom, Belgium, Netherlands, France, Israel
UMC Utrecht
Dutch Colorectal Cancer Group

Recruiting

Radioembolization in Elderly/ Fragile Patients With mCRC (CAIRO7)

Colorectal Cancer Metastatic

Netherlands
Hospital General Universitario de Alicante
Instituto de Salud Carlos III

Not yet recruiting

Ursodeoxycolic Acid for the Prevention of Relapsing Complications After Gallstone Acute Pancreatitis (OSOPOLAR)

Acute Pancreatitis Due to Gallstones

Spain

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