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Search clinical trials for: GABA-A Receptor Agonists

Total 143 results

NCT04278404

Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

Conditions: Coronavirus Infection (COVID-19); Pulmonary Arterial Hypertension; Urinary Tract Infections in Children; Hypertension; Pain; Hyperphosphatemia; Primary Hyperaldosteronism; Edema; Hypokalemia; Heart Failure; Hemophilia; Menorrhagia; Insomnia; Pneumonia; Skin Infection; Arrythmia; Asthma in Children; Bronchopulmonary Dysplasia; Adrenal Insufficiency; Fibrinolysis; Hemorrhage; Attention Deficit Hyperactivity Disorder; Multisystem Inflammatory Syndrome in Children (MIS-C); Kawasaki Disease; Coagulation Disorder; Down Syndrome
NCT04273776

Enrolling by invitation

A Comparison of the Physiological and Behavioral Effects of Suvorexant and Zolpidem in Healthy Volunteers: A Randomized, Double-blind, Placebo Controlled Study

Conditions: Performance Enhancing Product Use
NCT04118387

Not yet recruiting

Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment

Conditions: Sleep Disordered Breathing; Able Bodied
NCT04102345

Enrolling by invitation

Lavender vs Zolpidem Sleep Quality During Diagnostic PSG

Conditions: Sleep
NCT04014387

Recruiting

Treatment of Disturbed Sleep in Progressive Supranuclear Palsy (PSP)

Conditions: Treatment
NCT03885141

Not yet recruiting

Biolab Zolpidem Orodispersible 1.0 mg, 1.75 mg and 3.5 mg to Treat Maintenance Insomnia Disorder.

Conditions: Insomnia Disorder
NCT03786120

Recruiting

The Efficacy of Lower Dose Zolpidem for Achieving Satisfactory Sleep in Women With Disordered Sleep

Conditions: Sleep Disorder
NCT03774810

Recruiting

Partial Reinforcement II: Three Approaches to Maintenance Therapy for Chronic Insomnia

Conditions: Insomnia; Insomnia Chronic
NCT03657355

Completed

Study to Evaluate the Abuse Potential of ACT-541468 in Healthy Recreational Drug Users

Conditions: Healthy Recreational Drug Users
NCT03657212

Recruiting

Enhancing Memory Consolidation in Older Adults

Conditions: Aging
NCT03621046

Completed

Use of Low-dose Zolpidem in Parkinson's Disease

Conditions: Parkinson Disease
NCT03526575

Completed

Optimize Astronaut Sleep Medication Efficacy and Individual Effects

Conditions: Sleep; Cognition; Pharmacologic Actions
NCT03436745

Recruiting

The Effects of Castration on the Pharmacokinetics of Zolpidem After Single Dose Administration In Men With Prostate Cancer Undergoing Androgen Deprivation Therapy Compared to Normal Healthy Females

Conditions: Prostatic Neoplasms
NCT03375034

Completed

Exploring the Role of the GABAergic Modulation in Pain Transmission in Human

Conditions: Neuropathic Pain
NCT03375203

Completed

A Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-42847922 in Participants With Insomnia Disorder

Conditions: Insomnia Disorders
NCT03371836

Completed

Use of Clobazam for Epilepsy and Anxiety

Conditions: Epilepsy; Anxiety
NCT03307005

Completed

Improving Sleep Quality in Heart Failure

Conditions: Sleep Disturbance; Heart Failure
NCT03297944

Completed

Sedative-Anxiolytic Effects on Simulated Driving Performance

Conditions: Psychomotor Impairment
NCT03269760

Completed

Multimodal Sleep Pathway for Shoulder Arthroplasty

Conditions: Sleep Disturbance; Shoulder Arthritis; Arthroplasty Complications; Perioperative/Postoperative Complications
NCT03196466

Recruiting

Population Pharmacokinetics of Antiepileptic in Pediatrics

Conditions: Epilepsy
NCT03160404

Recruiting

Zolpidem or Exercise for Insomnia?

Conditions: Chronic Insomnia
NCT03158025

Completed

A Study to Determine the Abuse Potential of Single Oral Doses of Lemborexant Compared to Zolpidem, Suvorexant and Placebo in Healthy, Non-Dependent, Recreational Sedative Users

Conditions: Insomnia Disorders
NCT03075241

Recruiting

Z-Drugs for Sleep Disorders in Alzheimer's Disease

Conditions: Sleep; Sleep Disorders; Insomnia; Alzheimer's Disease
NCT03056053

Completed

Study to Validate the Questionnaire Called IDSIQ™ in Patients With Insomnia Disorder

Conditions: Insomnia Disorder
NCT02948660

Recruiting

The Role of Sleep-modulating Drugs in the Recovery of Patients With Disorders of Consciousness

Conditions: Consciousness Disorders
NCT02839200

Completed

Efficacy and Safety of ACT-541468 in Adult Subjects With Insomnia Disorder

Conditions: Insomnia Disorder
NCT02817750

Completed

Pharmacokinetics Study of Zolpidem Hemitartarate Orodispersible Tablet 3.5 mg Formulation

Conditions: Healthy
NCT02818309

Unknown status

Lesogaberan in Chinese Patients With Refractory Reflux Symptoms

Conditions: Gastroesophageal Reflux Disease
NCT02814058

Completed

Pharmacokinetics Study of Zolpidem Hemitartarate Orodispersible Tablet 1.75 mg Formulation

Conditions: Healthy
NCT02783729

Completed

Study of the Efficacy and Safety of Lemborexant in Subjects 55 Years and Older With Insomnia Disorder (SUNRISE 1)

Conditions: Insomnia
NCT02778659

Completed

Hypnotic Intake and Motor and Cognitive Performances at High Altitude

Conditions: Physiology
NCT02726919

Unknown status

Clobazam Adjunctive Treatment of Adults With Refractory Focal Epilepsy

Conditions: Epilepsy
NCT02607696

Withdrawn

Pharmacokinetics of Zolpidem Orodispersible Tablet

Conditions: Healthy Volunteers
NCT02578472

Completed

Pilot Study to Evaluate the Duration of Effects on Simulated Car Driving and Cognitive Performance After a Single Dose of JNJ-42847922, Zolpidem and Placebo in Healthy Participants

Conditions: Healthy
NCT02564952

Completed

An Open-label Extension Study to Investigate Possible Drug-drug Interactions Between Clobazam and Cannabidiol

Conditions: Epilepsy
NCT02565108

Completed

A Randomized Controlled Trial to Investigate Possible Drug-drug Interactions Between Clobazam and Cannabidiol

Conditions: Epilepsy
NCT02484963

Completed

The Study of Spectrum of Sleep Disorders in Cirrhotic Patients and the Efficacy of Zolpidem in Cirrhotic Patients With Insomnia

Conditions: Cirrhosis
NCT02456532

Recruiting

Safety and Efficacy of Chronic Hypnotic Use 2

Conditions: Chronic Insomnia
NCT02374567

Terminated

Pharmacovigilance in Gerontopsychiatric Patients

Conditions: Dementia; Depression; Schizophrenia; Psychosomatic Disorders; Anxiety Disorders
NCT02353299

Completed

Assess the Effect of Zolpidem, Silenor & Placebo on Arousability, Ataxia/Balance & Cognition in Healthy Volunteers

Conditions: Healthy
NCT02205931

Unknown status

Ketogenic Diet in Infants With Epilepsy (KIWE)

Conditions: Epilepsy
NCT02187809

Terminated

Safety and Tolerability of Clobazam as Adjunctive Therapy in Paediatric Patients Aged ≥1 to ≤16 Years With Dravet Syndrome

Conditions: Dravet Syndrome
NCT02174094

Withdrawn

Clobazam as Adjunctive Therapy in Paediatric Patients Aged ≥1 to ≤16 Years With Dravet Syndrome

Conditions: Dravet Syndrome
NCT02139098

Terminated

Alternative Dosing Regimens in the Pharmacotherapy of Insomnia

Conditions: Insomnia
NCT02134366

Terminated

Clobazam Use in Epilepsia Partialis Continua - Pilot Study

Conditions: Epilepsia Partialis Continua; Kojewnikov's Epilepsy; Epilepsy
NCT02127918

Completed

Electrical Status Epilepticus in Sleep: Response of Neuropsychological Deficits and Epileptiform Activity to Clobazam Treatment

Conditions: Electrical Status Epilepticus in Sleep
NCT02096900

Completed

A Comparison of Midazolam and Zolpidem as Oral Premedication in Children

Conditions: Parental/Caregiver Anxiety; Child's Anxiety
NCT01987739

Completed

Study to Evaluate the Relative Abuse Potential of Almorexant in Recreational Drug Users

Conditions: Abuse Potential Study
NCT01932502

Unknown status

Evaluation of Onfi Conversion Therapy Replacing Clonazepam in Patients With Medically Refractory Epilepsy

Conditions: Refractory Epilepsy
NCT01920334

Unknown status

Effects of Zolpidem CR® in Sleep and Heart Recovery in Cardiac Intensive Care Unit Patients

Conditions: Acute Coronary Syndrome; Sleep Deprivation