Search clinical trials for: Gemfibrozil

Total 36 results

Elixir Pharmaceuticals

Completed

Drug-Drug Interaction Study of Mitiglinide and Gemfibrozil

Type 2 Diabetes Mellitus
VA Office of Research and Development
Parke-Davis; Fournier Labs

Completed

The VA HDL Intervention Trial (HIT): Secondary Prevention of Coronary Heart Disease in Men With Low HDL-Cholesterol and Desirable LDL-Cholesterol (HIT)

Coronary Heart Disease

United States
Wyeth is now a wholly owned subsidiary of Pfizer
Pfizer

Completed

Study Evaluating Potential Interaction Between SAM-531 And Gemfibrozil When Co-Administered

Healthy

Netherlands
Blu Caribe

Completed

Bioequivalence Study Between Two Oral Formulations of Gemfibrozil Tablets

Bioavailability
Forest Hills Lab

Not yet recruiting

Study to Evaluate the Safety, Tolerability, Efficacy, and PK of FHL-301 in Parkinson's Disease Patients.

Parkinson Disease
The Mind Research Network

Terminated

Exploration of Gemfibrozil as a Treatment for AUD

Alcohol Use Disorder

United States
Bellus Health Inc. - a GSK company

Completed

Evaluation of the Potential Drug-drug Interactions Between Gemfibrozil or Dabigatran Etexilate and Camlipixant

Healthy

Canada
Changhai Hospital
The First Affiliated Hospital with Nanjing Medical University; China Medical... and other collaborators

Unknown

A Multi-center Trial of Single-Branched Stent Graft System to Treat Aortic Dissection

Distal Aortic Dissection

China
National Taiwan University Hospital
National Science Council, Taiwan

Completed

Effect of Gemfibrozil on the Safety and Pharmacokinetics of Red Yeast Rice in Healthy Subjects

Healthy Subjects

Taiwan
National Institutes of Health Clinical Center (CC)

Completed

Drug Interaction Study of Lopinavir/Ritonavir and Gemfibrozil (GEM-PK)

Healthy Volunteers

United States
US Department of Veterans Affairs

Completed

Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides

Hypertriglyceridemia

United States
Gregory Jicha, 323-5550

Completed

Modulation of Micro-RNA Pathways by Gemfibrozil in Predementia Alzheimer Disease

Preclinical Alzheimer's Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Harvard Atherosclerosis Reversibility Project (HARP)

Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Coronary Disease
Centre for Addiction and Mental Health

Completed

Initial Screening of Gemfibrozil as a Novel Treatment for Tobacco Addiction

Nicotine Dependence

Canada
University of Texas Southwestern Medical Center

Completed

Gemfibrozil for Nicotine Smoking Cessation (GEMNIC)

Smoking Cessation

United States
Eli Lilly and Company

Completed

A Study of Evacetrapib in Healthy Participants

Healthy Volunteers

United States
Polaryx Therapeutics, Inc.

Not yet recruiting

Safety, Tolerability, and Efficacy of PLX-200 in Patients With CLN3

Juvenile Neuronal Ceroid Lipofuscinosis
AstraZeneca

Completed

To Evaluate the Effect of Gemfibrozil on the Pharmacokinetics and Pharmacodynamics of a Single Dose of AZD1656

Type 2 Diabetes Mellitus

Sweden
University Hospital Muenster

Withdrawn

Early Therapeutic Effects of Statins and Fibrates on Unstable Atherosclerotic Plaques

Atherosclerosis
Sanofi

Completed

Study of Drug-drug Interaction of the Effects of Gemfibrozil and Rifampicin on SAR442168 in Healthy Adult Subjects

Multiple Sclerosis

United States
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Effect of Multiple Doses of Gemfribozil on a Single Dose of ASP3652, and to Assess the Effects of Multiple Doses of ASP3652 on a Single Dose of Repaglinide in the Body of Healthy Subjects

Healthy Subjects | Drug-Drug Interaction (DDI)

United Kingdom
GlaxoSmithKline
Octagon Research Solutions, Incoporated

Completed

Study to Assess the Pharmacokinetics of GSK1278863A Coadministered With a High Fat Meal or an Inhibitor of CYP2C8 (Gemfibrozil) (DDI)

Anaemia

India
Boehringer Ingelheim

Completed

Relative Bioavailability of Single Dose Empagliflozin (BI 10773) When Co-administered With Multiple Doses of 600 mg Gemfibrozil Compared to Single Dose Treatment With Empagliflozin (BI 10773) When Given Alone in Healthy Volunteers

Healthy

Germany
National Institutes of Health Clinical Center (CC)

Completed

Endothelial Dysfunction as a Risk Factor in HIV Study

HIV Infections

United States
Aragon Pharmaceuticals, Inc.

Completed

Study to Assess Drug-Drug Interaction Between Itraconazole or Gemfibrozil and JNJ-56021927

Healthy

United States
Reata, a wholly owned subsidiary of Biogen
Covance

Completed

A Clinical Drug-Drug Interaction (DDI) Study With Omaveloxolone

Healthy Adult Subjects

United States
Eli Lilly and Company

Completed

The Effect of Gemfibrozil, Ketoconazole and Clarithromycin on the Amount of LY2409021 in the Bloodstream

Healthy Volunteers

United States
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

Drug-drug Interaction Study With MDV3100 (ASP9785) and Gemfibrozil and Itraconazole

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction

France
GlaxoSmithKline

Completed

A Pharmacokinetics Study of the Effects of GSK2118436 on Warfarin, the Effects of Ketoconazole and Gemfibrozil on GSK2118436, and the Effects of Repeat Doses of GSK2118436 in Subjects With BRAF Mutant Solid Tumors

Cancer

Australia, United States, United Kingdom
Seagen Inc.

Completed

A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib

Drug-drug Interaction

United States
Actelion

Completed

A Clinical Study to Investigate the Effect of Gemfibrozil or Rifampicin on Blood Concentrations of Selexipag in Healthy Subjects

Healthy Subjects

Germany
EMS

Completed

Efficacy and Safety of Pediatric Drugs in Nasal Congestion

Nasal Congestion

Brazil
Bristol-Myers Squibb

Completed

A Study to Assess the Effect of Itraconazole, Phenytoin and Gemfibrozil on the Drug Levels of BMS-986166 in Healthy Participants

Healthy Participants

United States
Bristol-Myers Squibb

Completed

A Study to Assess the Effect of Multiple Doses of Itraconazole, Gemfibrozil, or Carbamazepine on BMS-986278 in Healthy Participants

Healthy Participants

Canada
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Active, not recruiting

A Study to Investigate the Drug-drug Interactions (DDIs) of SKLB1028 With Itraconazole, Gemfibrozil or Rifampicin in Healthy Subjects

Healthy Subjects

China
Celgene

Completed

Drug-drug Interaction Study of Ozanimod With Inhibitor or Inducer of CYP2C8 and/or CYP3A

Healthy Volunteer

United States

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