Search clinical trials for: H3B-6527

Total 602 results

Eisai Inc.
H3 Biomedicine Inc.

Completed

A Study to Evaluate the Food-Effect of H3B-6527

Healthy Participants

United States
H3 Biomedicine Inc.
Eisai Inc.

Completed

Phase 1 Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of H3B-6527 in Participants With Advanced Hepatocellular Carcinoma

Liver Neoplasms | Hepatocellular Carcinoma | Advanced Hepatocellular Carcinoma | Liver Cancer | Hepatic Cancer | Hepatic Carcinoma

France, United States, Belgium, Spain, Taiwan, Korea, Republic of, Russian Federation, Canada, Italy, Singapore, United Kingdom
Provention Bio, Inc.

Completed

Phase 2a Study of PRV-6527 in Subjects With Moderately to Severely Active Crohn's Disease (PRINCE)

Crohn's Disease

Austria, Germany, Hungary, Poland, Russian Federation, Spain, Ukraine
Merck Sharp & Dohme LLC

Recruiting

Safety and Pharmacokinetic Study of Oral MK-8527 QM in Participants at Low-Risk for HIV-1 Infection (MK-8527-007)

HIV | HIV Pre-exposure Prophylaxis

United States, South Africa, Israel
Shandong New Time Pharmaceutical Co., LTD

Not yet recruiting

Study of F527 in Patients With Relapsed or Refractory Lymphoma

Relapsed/Refractory Lymphoma

China
PT Bio Farma

Completed

Immunogenicity and Safety of DTP/HB/Hib (Bio Farma)Compared to DTP/HB Given Simultaneously With Hib(Registered)Vaccine

Healthy

Indonesia
Myrexis Inc.

Completed

Multiple Dose Study of MPC-6827 in Subjects With Refractory Brain Metastases

Brain Neoplasms

United States
Boehringer Ingelheim

Completed

BI 6727 (Volasertib) Human ADME Trial in Various Solid Tumours

Neoplasms

Hungary
Boehringer Ingelheim

Completed

BI 6727 Administered Intravenously Every 3 Weeks in Patients With Solid Tumours

Neoplasms

Belgium
Boehringer Ingelheim

Completed

BI 6727 (Volasertib) in Combination With Cisplatin or Carboplatin in Patients With Advanced or Metastatic Solid Tumour

Neoplasms

Belgium
GlaxoSmithKline

Completed

A Study of Safety, Reactogenicity and Immunogenicity of HRV Vaccine in HIV Infected Infants in South Africa

Infections, Rotavirus

South Africa
PT Bio Farma

Completed

Protectivity and Safety of DTP/HB/Hib (Bio Farma) Vaccines in Infants, Batch Consistency, Multi Center Trial

Healthy

Indonesia
Merck Sharp & Dohme LLC

Not yet recruiting

A Study of MK-8527 in Participants With Moderate and Severe Renal Impairment (MK-8527-008)

Renal Impairment
Boehringer Ingelheim

Completed

Dose Finding Study of BI 6727 (Volasertib) in Patients With Various Solid Cancers

Neoplasms

Taiwan
Myrexis Inc.

Completed

Phase 1, Multiple Dose Study of MPC-6827 in Subjects With Refractory Solid Tumors

Refractory Solid Tumors

United States
PT Bio Farma

Completed

Comparison of Immunogenicity and Safety of DTP-HB-Hib (Bio Farma) With Pentabio® Vaccine Primed With Recombinant Hepatitis B

Safety | Immunogenicity

Indonesia
Boehringer Ingelheim

Completed

Intravenous BI 6727 (Volasertib) in 2nd Line Treatment of Urothelial Cancer

Neoplasms

United States, Taiwan
Eisai Inc.

Completed

Trial of H3B-6545, in Women With Locally Advanced or Metastatic Estrogen Receptor-positive, HER2 Negative Breast Cancer

Breast Cancer | Breast Neoplasms | Cancer, Breast | Breast Cancer Female | Estrogen Receptor Positive Tumor | Breast Adenocarcinoma | ER Positive | Estrogen-receptor Positive Breast Cancer

France, United Kingdom, United States
Sanofi Pasteur, a Sanofi Company

Completed

Safety of DTaP-IPV-Hep B-PRP~T Combined Vaccine Compared to Tritanrix-HepB/Hib™ and OPV Given at Age 2, 4, and 6 Months.

Hepatitis B | Pertussis | Tetanus | Diphtheria | Haemophilus Influenzae Type b

Peru, Mexico
Myrexis Inc.

Completed

Phase 2 Study MPC-6827 for Recurrent Glioblastoma Multiforme

Glioblastoma Multiforme

United States
Atea Pharmaceuticals, Inc.

Completed

Study of AT-527 in Healthy Subjects Under Fasting Conditions or With a Meal

Healthy Volunteer Study

Canada
Atea Pharmaceuticals, Inc.
Hoffmann-La Roche

Completed

Study of AT-527 in Healthy Subjects (R07496998)

Healthy Volunteer Study

Canada
Rigshospitalet, Denmark

Completed

Increase in Temperature in Children Undergoing MRI (HOT-MR)

Children, Only | Temperature Change, Body | Magnetic Field Exposure

Denmark
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity and Safety of a Meningococcal Conjugate Vaccine Given Concomitantly With Other Vaccines in Toddlers

Meningitis, Meningococcal

Korea, Republic of, Mexico, Russian Federation, Thailand
Mayo Clinic
Virginia Commonwealth University; Indiana University; Hennepin County Medical...

Completed

Use of F-652 in Patients With Alcoholic Hepatitis (TREAT 008)

Alcoholic Hepatitis

United States
Tobira Therapeutics, Inc.

Completed

A Proof of Concept Study to Evaluate the Antiviral Activity, Safety, and Pharmacokinetics of the CCR5 Antagonist TBR 652 in HIV 1-Infected, Antiretroviral Treatment-Experienced, CCR5 Antagonist-Naïve Patients

HIV-1 Infection
Atea Pharmaceuticals, Inc.

Terminated

Safety and Efficacy of AT-527 in Subjects With Moderate Coronavirus Disease (COVID-19) in a Hospital Setting

COVID-19

United States, Argentina, Belgium, Brazil, Egypt, Moldova, Republic of, Romania, South Africa, Spain, Ukraine
EVIVE Biotechnology

Completed

Placebo-controlled Trial of F-627 in Women With Breast Cancer Receiving Myelotoxic Chemotherapy

Breast Cancer | Neutropenia

United States
EVIVE Biotechnology

Withdrawn

Study of F-652 in Subjects With Corona Virus Disease 2019 (COVID-19) Pneumonia

COVID-19 Pneumonia
Abbott

Completed

Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of ABT-652 in Subjects With Excessive Daytime Sleepiness

Sleep Disorder

United States
Hemavant Sciences GmbH

Terminated

A Study of H3B-8800 (RVT-2001) in Participants With Lower Risk Myelodysplastic Syndromes (Encore-MDS)

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute | Leukemia, Myelomonocytic, Chronic

Korea, Republic of, United States, Taiwan, Belgium, France, Spain, Italy
Sanofi Pasteur, a Sanofi Company

Completed

Comparison of DTaP-IPV-Hep B-PRP~T Combined Vaccine to CombAct-HIB® Concomitantly Given With Engerix B® Paediatric and OPV

Hepatitis B | Pertussis | Diphtheria | Polio | Haemophilus Influenzae Type b

South Africa
Atea Pharmaceuticals, Inc.

Completed

The Study of Bemnifosbuvir in Healthy Japanese Subjects

Healthy Volunteer Study

United States
Aspen Medical Products

Terminated

A Prospective, Multicenter, Randomized Control Study To Determine Clinical Effectiveness, Patient Wellness and Cost of Pain Related Care of In-Elastic Lumbar Sacral Orthoses Versus Standard Medical Treatment in Patients Presenting With Acute Low Back Pain In Primary Care Centers (The ARREST Study) (ARREST)

Back Pain | Low Back Pain
Boryung Pharmaceutical Co., Ltd
Covance

Completed

Fimasartan (BR-A-657) Multiple Oral Dose in Healthy Subjects

Essential Hypertension
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Bemalenograstim Alfa for the Prevention in Patients With Colorectal Cancer/Pancreatic Cancer

Colorectal Cancer | Pancreatic Cancer

China
EVIVE Biotechnology

Completed

Neulasta-controlled Trial of F-627 in Women With Breast Cancer Receiving Myelotoxic Chemotherapy

Breast Cancer | Neutropenia

United States
Serum Institute of India Pvt. Ltd.
PATH

Terminated

Study Comparing DTP-HB-Hib by Disposable-Syringe Jet Injector To Vaccination By Needle And Syringe In Infants

Immune Response to DTP-HB-Hib Vaccine

India
PT Bio Farma

Completed

Antibody Persistence, Immune Response and Safety After Doses of Pentabio Vaccine

Healthy

Indonesia
EVIVE Biotechnology

Terminated

Study of F-652 (IL-22:IgG2 Fusion Protein) in Patients With Moderate to Severe COVID-19

Covid19

United States
Atea Pharmaceuticals, Inc.
Hoffmann-La Roche

Completed

Bronchopulmonary PK of AT-527 (R07496998)

Healthy Volunteer Study

United Kingdom
Atea Pharmaceuticals, Inc.
Hoffmann-La Roche

Completed

Mass Balance Study of AT-527 in Healthy Adult Male Subjects (R07496998)

Healthy Volunteer Study

United States
Atea Pharmaceuticals, Inc.

Completed

Study of AT-527 in Combination With Daclatasvir in Subjects With Hepatitis C Virus (HCV) Infection

Hepatitis C Virus Infection | Hepatitis C | Hepatitis C, Chronic | Chronic Hepatitis C | HCV Infection

Belgium, Mauritius, Moldova, Republic of
Merck Sharp & Dohme LLC

Completed

MK-8527 Single-Dose Trial in HIV-1 Infected Participants (MK-8527-004)

Human Immunodeficiency Virus

Romania, South Africa
Boryung Pharmaceutical Co., Ltd

Completed

Efficacy of fimaSartan on arTerIal stiFFness iN patiEntS With HypertenSion (STIFFNESS)

Hypertension

Korea, Republic of
Northwestern University
National Cancer Institute (NCI); National Comprehensive Cancer Network

Withdrawn

Volasertib and Vincristine Sulfate Liposome in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia

Recurrent Adult Acute Lymphoblastic Leukemia | Refractory Adult Acute Lymphoblastic Leukemia

United States
Atea Pharmaceuticals, Inc.

Recruiting

Study of Bemnifosbuvir in Subjects With Normal and Impaired Hepatic Function

Hepatic Impairment | Healthy Volunteer

United States
EVIVE Biotechnology

Completed

Trial to Compare the Efficacy and Safety of F-627 and GRAN® (F-627)

Breast Cancer

China
Atea Pharmaceuticals, Inc.

Recruiting

Study of AT-527 in Subjects With Normal and Impaired Renal Function

Renal Impairment | Healthy Volunteer

Canada
Myrexis Inc.

Unknown

Phase 1 Study of MPC-6827 and Carboplatin in Recurrent/Relapsed Glioblastoma Multiforme

Glioblastoma Multiforme

United States

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