Search clinical trials for: IDN-6556

Total 9996 results

University of Alberta
Conatus Pharmaceuticals Inc.

Completed

Caspase Inhibition in Islet Transplantation

Diabetes

Canada
Conatus Pharmaceuticals Inc.
Idun Pharmaceuticals

Completed

A Caspase Inhibitor in Chronic Hepatitis C (HCV) Patients

Hepatitis C, Chronic

United States
Conatus Pharmaceuticals Inc.

Completed

PK and PD Study of IDN-6556 in Subjects With Hepatic Impairment and Matched Healthy Volunteers

Liver Diseases | Digestive System Diseases | Hepatic Impairment

United States
Conatus Pharmaceuticals Inc.

Completed

PK and PD Study of IDN-6556 in Subjects With Severe Renal Impairment and Matched Healthy Volunteers

Kidney Diseases | Renal Insufficiency | Renal Impairment | Kidney Disease

United States
Conatus Pharmaceuticals Inc.
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Terminated

Study of IDN-6556 in Patients With Severe Alcoholic Hepatitis and Contraindications to Steroid Therapy (AH)

Alcoholic Hepatitis

United States
Conatus Pharmaceuticals Inc.
Idun Pharmaceuticals

Completed

Safety and Efficacy Study of a Caspase Inhibitor in Patients Undergoing Liver Transplantation

Liver Transplantation | Hepatitis | Carcinoma, Hepatocellular | Cholestasis

United States, Germany
Conatus Pharmaceuticals Inc.

Completed

Emricasan, a Caspase Inhibitor, for Evaluation in Subjects With Non-Alcoholic Steatohepatitis (NASH) Fibrosis (ENCORE-NF)

Liver Diseases | Fibrosis | Non-alcoholic Steatohepatitis

United States, Spain, Germany
Conatus Pharmaceuticals Inc.

Completed

A Study of IDN-6556 in Cirrhotic Subjects With Portal Hypertension (PH)

Liver Cirrhosis | Portal Hypertension | Hepatic Cirrhosis

United States
Conatus Pharmaceuticals Inc.

Completed

A Study of IDN-6556 in Subjects With Liver Cirrhosis (LC)

Liver Cirrhosis | Hepatic Cirrhosis

United States
Conatus Pharmaceuticals Inc.

Terminated

Pharmacokinetic and Pharmacodynamic Study of IDN-6556 in ACLF

Liver Cirrhosis | Acute on Chronic Hepatic Failure | Acute Liver Failure | Acute Alcoholic Hepatitis

United States, United Kingdom
Conatus Pharmaceuticals Inc.

Completed

A Trial of IDN-6556 in Post Orthotopic Liver Transplant for Chronic HCV (POLT-HCV-SVR)

Liver Cirrhosis | Hepatic Fibrosis | Liver Fibrosis | Hepatic Cirrhosis

United States
Conatus Pharmaceuticals Inc.

Completed

A Study of IDN-6556 in Subjects With NAFLD and Raised Transaminases (NAFLD)

Non-alcoholic Fatty Liver Disease | Nonalcoholic Steatohepatitis

United States
Conatus Pharmaceuticals Inc.

Unknown

Emricasan, a Caspase Inhibitor, for Treatment of Subjects With Decompensated NASH Cirrhosis (ENCORE-LF)

Decompensated Cirrhosis

United States
Kyowa Kirin Co., Ltd.

Completed

A Study of Single and Multiple Doses of KW-6356 in Healthy Subjects

Parkinson's Disease

Japan
LivaNova

Completed

Optimal Anti-tachycardia Therapy in Implantable Cardioverter-defibrillator (ICD) Patients Without Pacing Indications (OPTION)

Tachycardia

France, Germany, Portugal, Italy, Canada, United States, Belgium, Netherlands, United Kingdom
Bial R&D Investments, S.A.

Recruiting

Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PD (ACTIVATE)

Parkinson's Disease

United States, Spain, France, Italy, Netherlands, Germany, United Kingdom, Canada, Poland, Portugal, Sweden
Kyowa Kirin, Inc.

Completed

Single-dose Study to Investigate the Plasma PK of KW-6356 and Its Major Metabolite

Hepatic Impairment

United States
Kyowa Kirin, Inc.

Completed

Phase 1, Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-KW-6356

Healthy Male Subjects

United States
Novo Nordisk A/S

Recruiting

Investigation of Safety, Tolerability and Pharmacokinetics of Multiple Doses of NNC0113-6856 in Healthy Participants, Including a Subset of Healthy Japanese Participants

Healthy Participants

Germany
Kyowa Kirin Co., Ltd.

Completed

A Study of KW-6356 in Subjects With Early Parkinson's Disease

Parkinson's Disease

Japan
Merck Sharp & Dohme LLC

Recruiting

Study of MK-6552 in Participants With Narcolepsy Type 1 (MK-6552-004)

Narcolepsy

United States
Novo Nordisk A/S

Completed

A Research Study of a New Medicine NNC0113-6856 in Healthy Males

Type 2 Diabetes | Healthy Volunteers

Germany
Bial R&D Investments, S.A.

Completed

Mass Balance Recovery and Metabolite Identification of Carbon-14 BIA 28-6156

Parkinson Disease

United Kingdom
Wake Forest University Health Sciences
Procter and Gamble

Active, not recruiting

Shaving Satisfaction in Males With Skin Irritation From Shaving

Pseudofolliculitis Barbae

United States
Concert Pharmaceuticals

Completed

Food Effect Study of CTP-656 in Healthy Male Volunteers

Healthy

Australia
Kyowa Kirin Co., Ltd.

Completed

A Study of KW-6356 in Patients With Parkinson's Disease on Treatment With Levodopa-containing Preparations

Parkinson's Disease

Japan
Pfizer

Terminated

Study Evaluating Safety Of BMP-655/ACS As An Adjuvant Therapy For Rotator Cuff Repair

Rotator Cuff Tear

Germany, Netherlands
Nuvalent Inc.

Recruiting

A Study of NVL-655 in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)

Metastatic Solid Tumor | Locally Advanced Solid Tumor

Canada, United States, Australia, Spain, United Kingdom, France, Singapore
Concert Pharmaceuticals

Completed

Healthy Volunteer Solid Oral Dose and Multiple Ascending Dose Evaluation of CTP-656

Healthy

Australia
Kubota Vision Inc.
Otsuka Pharmaceutical Co., Ltd.

Completed

Safety/Efficacy Study: OPA-6566 Ophthalmic Solution in Subjects With Primary Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Primary Open-angle Glaucoma

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Immunogenicity of an HIV-1 gp41 MPER-656 Liposome Vaccine in Healthy, HIV-uninfected Adult Participants

HIV Infections

United States
Takeda
Shire; Takeda Development Center Americas, Inc.

Recruiting

A Study of TAK-755 in Participants With Congenital Thrombotic Thrombocytopenic Purpura

Thrombotic Thrombocytopenic Purpura (TTP)

China, United States, France, Japan, Poland, Germany, Austria, Spain, Italy, Switzerland, United Kingdom
NantCell, Inc.

Terminated

QUILT-3.026: AMG 655 in Combination With AMG 479 in Advanced, Refractory Solid Tumors

Sarcoma | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Metastatic Cancer | Solid Tumors | Locally Advanced
Amgen

Completed

A Phase 1b/2 Study of AMG 655 in Combination With Paclitaxel and Carboplatin for the First-Line Treatment of Advanced Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer
Takeda
Takeda Development Center Americas, Inc.

Recruiting

A Study of TAK-755 (rADAMTS13) With Little to No Plasma Exchange (PEX) Treatment in Adults With Immune-mediated Thrombotic Thrombocytopenic Purpura (iTTP)

Thrombotic Thrombocytopenic Purpura (TTP)

United States, Spain, Italy, Greece, United Kingdom, Argentina, Poland, Austria
Pfizer

Terminated

A Safety Study Of BMP-655/ACS As An Adjuvant Therapy For Treatment Of Rotator Cuff Tears

Rotator Cuff Tear

Japan
2C Tech Corp

Completed

Intravitreal Injection of SeeQ CdSe 655 Alt Nanoparticles for Patients With Degenerative Retinal Diseases

Retinitis Pigmentosa

Mexico
Bayer

Completed

Non-interventional Multi-center Study on Patients Under Routine Treatment of Pulmonary Arterial Hypertension (PAH) With Inhaled Iloprost Using I-Neb as a Device for Inhalation (COMPHI)

Pulmonary Hypertension

Portugal
Bayer
Nektar Therapeutics

Completed

A Study to Determine the Correct Dose of Amikacin Which is Delivered Directly to the Lungs of Ventilated Patients as an Aerosol Via an Investigational Device Called the Pulmonary Delivery Device System (PDDS)

Pneumonia

France, Spain, United States
Apira Science, Inc.

Completed

Treatment of Androgenetic Alopecia in Males and Females (LLLT)

Androgenetic Alopecia

United States
ELA Medical, Inc.

Completed

Ovatio DR and VR Implantable Cardioverter Defibrillators Post-approval Study (Post-Ovatio)

Sudden Cardiac Death

United States
Baxalta now part of Shire
Takeda Development Center Americas, Inc.

Recruiting

A Study of BAX 930 in Children, Teenagers, and Adults Born With Thrombotic Thrombocytopenic Purpura (TTP)

Thrombotic Thrombocytopenic Purpura (TTP)

United States, Spain, Poland, Italy, Germany, France, Switzerland, Austria, Japan, United Kingdom
Bayer
Nektar Therapeutics

Completed

Safety, Tolerability and Pharmacokinetics of Aerosolized Amikacin in Intubated and Mechanically-ventilated Patients With Nosocomial Pneumonia

Pneumonia

United States, France
Bayer
Nektar Therapeutics

Completed

Inhaled Amikacin Solution BAY41-6551 as Adjunctive Therapy in the Treatment of Gram-Negative Pneumonia (INHALE 1)

Pneumonia, Bacterial

Korea, Republic of, Taiwan, United States, Canada, Philippines, Turkey, Thailand, Australia, Mexico, Colombia, Czechia, Brazil
Peking Union Medical College Hospital
National Institute for Biomedical Imaging and Bioengineering (NIBIB)

Unknown

177Lu-EB-PSMA617 in Patients With Metastatic Castration-resistant Prostate Cancer

Metastatic Castration-resistant Prostate Cancer

China
Amgen

Completed

Conatumumab/Panitumumab Combination Metastatic Colorectal Cancer Study

Metastatic Colorectal Cancer | Colorectal Cancer | Rectal Cancer | Colon Cancer | Oncology
Sorrento Therapeutics, Inc.

Suspended

Study to Assess Abivertinib in Combination With Abiraterone in Metastatic Castration Resistant Prostate Cancer

Prostate Cancer | Prostate Cancer Metastatic

United States
Vertex Pharmaceuticals Incorporated

Recruiting

A Study To Evaluate the Relative Bioavailability, Food Effect, and Dose Proportionality of a Granule Formulation of Vanzacaftor/Tezacaftor/Deutivacaftor(VNZ/TEZ/D-IVA)

Cystic Fibrosis

United States
Vertex Pharmaceuticals Incorporated

Enrolling by invitation

Evaluation of Long-Term Safety and Efficacy of Vanzacaftor/Tezacaftor/Deutivacaftor in Cystic Fibrosis Participants 1 Year of Age and Older

Cystic Fibrosis

United States, Australia, Germany, Sweden, Switzerland, France, Netherlands, United Kingdom
Vertex Pharmaceuticals Incorporated

Enrolling by invitation

A Study of Vanzacaftor/Tezacaftor/Deutivacaftor (VNZ/TEZ/D-IVA) in Healthy Adult Panelists

Cystic Fibrosis

United States

Search clinical trials for: IDN-6556

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