Search clinical trials for: IMO-2125

Total 1846 results

Idera Pharmaceuticals, Inc.

Completed

A Study of Intratumoral IMO-2125 in Patients With Refractory Solid Tumors (ILLUMINATE-101)

Melanoma | Refractory Solid Tumors

United States, Israel
Capstone Therapeutics

Terminated

A Study to Evaluate the Safety and Effectiveness of Different Doses of Chrysalin in Adults Who Have a Broken Wrist

Radius Fracture

United States
Idera Pharmaceuticals, Inc.

Completed

Study of Combination Treatment With IMO-2125 and Ribavirin in Naïve Hepatitis C-infected, Genotype 1 Patients

Hepatitis C, Treatment Naïve, Genotype 1 Patients

France
A.J.M. van den Eertwegh
Idera Pharmaceuticals, Inc.

Recruiting

A Randomized Controlled Phase II Trial With Intradermal IMO-2125 in Pathological Tumor Stage (p) T3-4 cN0M0 Melanoma (INTRIM)

Malignant Melanoma

Netherlands
Idera Pharmaceuticals, Inc.

Completed

Placebo-controlled, Dose-escalation Study of the Safety of IMO-2125 (Immunomodulatory Oligonucleotide) in Hepatitis C-infected Patients

Hepatitis C

United States, Puerto Rico
Idera Pharmaceuticals, Inc.

Completed

A Phase 2 Study to Assess the Safety and Efficacy of IMO-2125 With 8 mg Ipilimumab in Patients With Metastatic Melanoma

Metastatic Melanoma

United States
Idera Pharmaceuticals, Inc.
Bristol-Myers Squibb

Active, not recruiting

Study of Tilsotolimod in Combination With Nivolumab and Ipilimumab for the Treatment of Solid Tumors (ILLUMINATE-206)

Solid Tumor

United States
Idera Pharmaceuticals, Inc.
Bristol-Myers Squibb

Terminated

A Study of Tilsotolimod in Combo With Ipilimumab vs Ipilimumab Alone in Subjects With Anti-PD-1 Refractory Melanoma

Metastatic Melanoma

United States, Canada, Spain, United Kingdom, France, Australia, Germany, Italy, Netherlands, Sweden, Czechia
Idera Pharmaceuticals, Inc.

Completed

A 12-week Dose-Ranging Trial in Patients With Moderate to Severe Plaque Psoriasis (8400-201)

Plaque Psoriasis

Netherlands
Grünenthal GmbH

Completed

A Clinical Study in Healthy Subjects Which Aims to Investigate the Safety, the Tolerability and the Effects of GRT0151Y and How the Compound is Taken up and Excreted From the Body

Acute Pain

France
Dokuz Eylul University

Completed

The Effect of Inspiratory Muscle Warm-Up in Patients With COPD

Chronic Obstructive Pulmonary Disease | COPD

Turkey
Idera Pharmaceuticals, Inc.

Completed

Trial of IMO-8400 in Adult Patients With Dermatomyositis (8400-211)

Dermatomyositis

United States, Hungary, United Kingdom
Idera Pharmaceuticals, Inc.

Completed

Trial of IMO-3100 in Patients With Moderate to Severe Plaque Psoriasis

Moderate to Severe Plaque Psoriasis | Actively Extending Plaque Psoriasis

United States
Emory University
University of Calgary; Children's Hospital Medical Center, Cincinnati; Heidelberg... and other collaborators

Recruiting

Endovascular Therapy for Low NIHSS Ischemic Strokes (ENDOLOW)

Cerebral Ischemia

United States, Canada, Germany
Idera Pharmaceuticals, Inc.

Completed

Dose Escalation Study in Patients With Relapsed or Refractory DLBCL and MyD88 L265P Mutation

Diffuse Large B Cell Lymphoma

United States
Idera Pharmaceuticals, Inc.

Terminated

Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia (8400-401)

Waldenstrom's Macroglobulinemia

United States
Idera Pharmaceuticals, Inc.

Completed

Study of IMO-2055 in Metastatic or Locally Recurrent Clear Cell Renal Carcinoma

Renal Cell Carcinoma

United States
Nanfang Hospital, Southern Medical University

Recruiting

Effect of IMO on Intestinal Microbiota Translocation in Cirrhosis

Decompensated Cirrhosis

China
Merck Sharp & Dohme LLC

Completed

Safety, Tolerability, and Immunogenicity of the Human Cytomegalovirus Vaccine (V160) in Healthy Adults (V160-001)

Cytomegalovirus Infections
Inovio Pharmaceuticals
GeneOne Life Science, Inc.; Defense Advanced Research Projects Agency

Completed

Open-Label Study of INO-4212 With or Without INO-9012, Administered IM or ID Followed by Electroporation in Healthy Volunteers

Ebola Vaccine

United States
EMD Serono

Completed

Safety of Adding IMO-2055 to Erlotinib + Bevacizumab in 2nd Line Treatment for Patients With NSCLC

Non-Small Cell Lung Cancer

United States
Aquinox Pharmaceuticals (Canada) Inc.
Quotient Clinical

Completed

Phase 1 Absorption Distribution Metabolism and Excretion of AQX-1125 (ADME)

Healthy Volunteer

United Kingdom
Inovio Pharmaceuticals

Completed

A Study of DNA Vaccine With Electroporation for the Prevention of Disease Caused by H1 and H5 Influenza Virus

Healthy

United States
University of Illinois at Chicago
TÜBİTAK

Not yet recruiting

High-intensity Inspiratory Muscle Training as a Pre-cardiac Rehabilitation in Heart Disease

CABG | Coronary Artery Bypass Graft

United States
Hadassah Medical Organization
XTL Biopharmaceuticals

Withdrawn

Safety, Tolerability and Efficacy of XTL 2125 in HCV-Infected Patients Who Are Interferon-Alpha Non-Responders or Relapsers

Chronic Hepatitis C Virus Infection

Israel
Inovio Pharmaceuticals
University of Pennsylvania

Completed

Immunotherapy in Subjects With HPV-6 Associated Aerodigestive Precancerous Lesions and Malignancies

Aerodigestive Precancerous Lesions and Malignancies

United States
Guangzhou Institute of Respiratory Disease

Unknown

NPPV Added Inspiratory Muscle Training in Severe COPD

Chronic Obstructive Pulmonary Disease | Hypercapnic Respiratory Failure

China
Johns Hopkins University

Not yet recruiting

Preoperative Optimization to Improve Functional Status

Pulmonary Atelectasis | Pneumonia, Ventilator-Associated

United States
Kyowa Hakko Bio Co., Ltd.

Recruiting

Prebiotic Effects on Gut Microbiota, Gut Comfort and Immune Function

Gastrointestinal Diseases | Healthy

Singapore
Terrence J Bradley, MD
Imago BioSciences, Inc., a subsidiary of Merck & Co., Inc., (Rahway, New...

Recruiting

IMG-7289 in Patients With Essential Thrombocythemia (ET) or Polycythemia Vera (PV)

Polycythemia Vera | Essential Thrombocythemia

United States
Imara, Inc.

Withdrawn

Selective PDE9 Inhibition With IMR-687 in Adults With Heart Failure With Preserved Ejection Fraction (SP9In-HFpEF)

Heart Failure With Preserved Ejection Fraction
Aquinox Pharmaceuticals (Canada) Inc.

Completed

Efficacy and Safety of AQX-1125 in Unstable COPD (FLAGSHIP)

COPD

United States, New Zealand, Poland, Australia, Denmark, Finland, Hungary, Sweden
Brno University Hospital

Recruiting

Inspiratory Muscle Training and COPD

Chronic Obstructive Pulmonary Disease

Czechia
Hong Kong Baptist University

Not yet recruiting

A Chinese Herbal Medicine for IBS-C (CDD2105RCT1)

Constipation-predominant Irritable Bowel Syndrome
Aptinyx
Worldwide Clinical Trials

Completed

Efficacy and Safety of NYX-2925 in Subjects With Fibromyalgia

Fibromyalgia

United States
Aquinox Pharmaceuticals (Canada) Inc.
Innovaderm Research Inc.

Completed

Pilot Efficacy and Safety Study of AQX-1125 in Atopic Dermatitis (KINSHIP)

Atopic Dermatitis

Canada
Istanbul University

Not yet recruiting

Effects of Inspiratory Muscle Training on Diaphragm Thickness, Respiratory Muscle Strength and Balance in Dancers.

Athletic Injuries
Hospital Universitari Vall d'Hebron Research Institute

Not yet recruiting

Can High Intensity Inspiratory Muscle Training Improve Inspiratory Muscle Strength and Accelerate Weaning in Medical Patients With Difficulty on Weaning?

Weaning Failure

Spain
Instituto de Cardiologia do Rio Grande do Sul

Not yet recruiting

Inspiratory Muscle Training X CardioBreath App Effects On Vagal Modulation And Pulse Wave Velocity (CardioBreath)

Vascular Stiffness | Autonomic Imbalance | Postmenopausal Disorder

Brazil
Dokuz Eylul University

Completed

Effects of Home-based Inspiratory Muscle Training in Patients With IPF

Idiopathic Pulmonary Fibrosis | IPF

Turkey
Eli Lilly and Company

Completed

An Open-Label, Dose-Escalation Study of IMC-20D7S In Participants With Malignant Melanoma

Malignant Melanoma

United States
Universitas Katolik Widya Mandala Surabaya

Completed

Pre-meal High-performance Inulin Supplementation in Healthy Non-diabetic Subjects

Diet, Healthy

Indonesia
Ruijin Hospital

Recruiting

Evaluating Omitting of Internal Mammary Irradiation Among Early Stage Intermediate Risk (N1) Breast Cancer

Breast Cancer

China
Universidade Federal do Rio Grande do Norte

Completed

Intensity, Specificity and Reversibility of Inspiratory Muscle Training in Asthmatics

Asthma

Brazil
Medical University of Graz

Completed

Optical Quality After Implantation of a Spherical or Aspherical Intraocular Lens in Hypermetropic Patients

Cataract | Spherical Aberrations | Intraocular Lenses | Depth of Focus

Austria
Johnson & Johnson Vision Care, Inc.

Completed

Evaluating Soft Contact Lens Prototypes for Myopia Control

Visual Acuity

China
Inflammatix

Withdrawn

Sepsis Prognosis and Diagnosis in the Emergency Department (SPEED)

Respiratory Tract Infections | Sepsis | Urinary Tract Infections | Intra-Abdominal Infections | Skin and Soft Tissue Infection | Suspected Meningitis/Encephalitis or Any Other Infection
KU Leuven

Recruiting

Improving Our Understanding of Respiratory Muscle Training to Facilitate Weaning From Mechanical Ventilation in the ICU (TrainToWean)

Weaning Failure

Belgium
Neuropore Therapies Inc.
Celerion

Completed

A Study to Assess the Safety, Tolerability and PK of NPT520-34 in Healthy Subjects

Healthy Volunteers

United States
University of Lausanne

Not yet recruiting

The Effects of Inspiratory Muscle Training on Endurance Performance in Trained Athletes Under Normoxic and Hypoxic Conditions: A Gender-based Comprehensive Study (RespiPerf)

Hypoxia, Altitude

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