Search clinical trials for: Inhaled mannitol

Total 1208 results

Pharmaxis

Completed

Crossover Trial Determining the Efficacy of Dry Powder Mannitol to Improve Lung Function in Subjects Aged 6-17 Years

Cystic Fibrosis

United Kingdom
Pharmaxis

Completed

Inhaled Mannitol as a Mucoactive Therapy for Bronchiectasis

Bronchiectasis

United States, United Kingdom, Australia, New Zealand, Argentina, Belgium, Chile, Germany, Netherlands
Pharmaxis

Completed

A Pilot Study to Investigate Administration of Mannitol Via a Novel Dry Powder Inhaler Device

Healthy | Bronchiectasis

Australia
Pharmaxis
ethica Clinical Research Inc.; Europe: KasaConsult bvba, Hoegaarden, Belgium; Argentina: Resolution Latin America; Buenos Aires, Argentina

Completed

Long Term Administration of Inhaled Mannitol in Cystic Fibrosis

Cystic Fibrosis

United States, France, Belgium, Canada, Argentina, Germany, Netherlands
Pharmaxis

Completed

A Phase 2 Study to Determine the Safety and Efficacy of Inhaled Dry Powder Mannitol in Cystic Fibrosis

Cystic Fibrosis

Australia, New Zealand
Pharmaxis

Completed

A Safety and Efficacy Trial of Inhaled Mannitol in Adult Cystic Fibrosis Subjects

Cystic Fibrosis

United States, Spain, Israel, Belgium, Czechia, South Africa, Italy, Mexico, Argentina, Australia, Canada, Hungary, New Zealand, Poland, Romania, Russian Federation, Slovakia, Ukraine
Tim Corcoran

Completed

Repeatability and Response Study of Absorptive Clearance Scans

Cystic Fibrosis

United States
University of British Columbia

Completed

Double-blind Trial of Mannitol Cream to Block the Effect of Capsaicin Cream (LipTRP)

Pain

Canada
Orion Corporation, Orion Pharma

Completed

Inspiratory Flow Parameters and Handling of Easyhaler and Turbuhaler Inhalers (PIFECO)

Pulmonary Disease, Chronic Obstructive | Asthma

United Kingdom, Finland
Seoul National University Hospital

Unknown

Mannitol Brain Relaxation Effect (MANNITOL)

Supratentorial Neoplasms

Korea, Republic of
Pharmaxis

Completed

Comparison of Inhaled Mannitol and rhDNase in Children With Cystic Fibrosis

Cystic Fibrosis

United Kingdom
Synspira, Inc.

Terminated

A Study of the Safety and Tolerability of Inhaled SNSP113 in Healthy Subjects and Subjects With Stable Cystic Fibrosis

Lung Diseases | Cystic Fibrosis | Pulmonary Disease | Antibiotic Resistant Infection | Respiratory Tract Disease | Cystic Fibrosis Pulmonary Exacerbation | Lung Inflammation | Burkholderia Infections | Lung Infection | Multi-antibiotic Resistance | Pulmonary Inflammation | Lung Infection Pseudomonal | Cystic Fibrosis... and other conditions

United Kingdom
Shandong University

Unknown

Individualized Volume of Oral Contrast Agent in CT Enterography

CTE

China
GlaxoSmithKline

Completed

Study to Assess the Safety and PK of GSK573719 and GSK573719/GW642444(VI) Combination in Healthy Subjects and Subjects With Severe Renal Impairment

Pulmonary Disease, Chronic Obstructive

Czechia, Hungary
GlaxoSmithKline

Completed

A Study to Assess the Effects of GSK573719/VI Combination and GSK573719 Monotherapy in Subjects With Moderate Hepatic Impairment and Matched Healthy Volunteers

Pulmonary Disease, Chronic Obstructive

Hungary, Slovakia
Galecto Biotech AB

Completed

RCT (Randomized Control Trial) of TD139 vs Placebo in HV's (Human Volunteers) and IPF Patients

Idiopathic Pulmonary Fibrosis

United Kingdom
Pharmaxis

Withdrawn

A Pilot Safety Study of Inhaled Dry Powder Mannitol in Acute Exacerbations of COPD

COPD | Exacerbation

Australia
University of British Columbia

Completed

Mannitol Cream for Post Herpetic Neuralgia (MannitolPHN)

Neuralgia, Postherpetic

Canada
Pharmaxis

Completed

High Dose Inhaled Mannitol Study

Bronchiectasis

Australia
Pharmaxis

Completed

Mannitol Dose Response Study in Cystic Fibrosis

Cystic Fibrosis

Canada, Argentina
Makerere University
University of Copenhagen

Completed

Inhaled Corticosteroids in U-5 Children With Acute Respiratory Infection in Uganda: A Randomised Trial (ICS)

Bacterial Pneumonia | Acute Asthma | Viral Pneumonia

Uganda
Kuopio University Hospital
John Hunter Hospital

Recruiting

Reference Ranges for the Cough Responsiveness to Inhaled Mannitol

Cough

Australia, Finland
Abela Pharmaceuticals, Inc.
Ohio State University; University of California, Irvine; Dr. Mahajan's Hospital...

Unknown

Controlled Trial of ABELADRUG200 in Closed, Severe Head Injury (ABELADRUG200)

Severe Head Trauma

United States
University of North Carolina, Chapel Hill
Chiesi USA, Inc.

Recruiting

Inhaled Mannitol on Mucociliary Clearance in Moderate to Severe Cystic Fibrosis

Cystic Fibrosis

United States
Imam Abdulrahman Bin Faisal University

Completed

Mannitol Improves Cerebral Oxygen Saturation

Anesthesia

Saudi Arabia
Thomas Jefferson University

Unknown

Comparison of Two Different Medications Used to Treat Elevated Intracranial Pressure

Increased Intracranial Pressure
University of Wisconsin, Madison
National Heart, Lung, and Blood Institute (NHLBI); Pharmaxis

Completed

Mannitol Bronchoprovocation Challenge Ancillary Study/ACRN

Asthma

United States
Bispebjerg Hospital

Unknown

Bronchial Response to Mannitol and Inflammation in Steroid Naive Asthmatics.

Asthma

Denmark
Institut d'Anesthesiologie des Alpes Maritimes
Institut National de la Santé Et de la Recherche Médicale, France; PT Kalbe...

Terminated

Sodium-Lactate and Traumatic Brain Injury

Intracranial Hypertension | Severe Trauma Brain Injury

France
University Hospital, Saarland
Else Kröner Fresenius Foundation

Unknown

Effects of Hemofiltration and Mannitol Treatment on Cardiopulmonary-Bypass Induced Immunosuppression

Inflammation

Germany
Brigham and Women's Hospital

Completed

Mannitol - Potential Role in Hemodialysis Initiation for Reduction of Intra-dialytic Hypotension

Intra-dialytic Hypotension

United States
GlaxoSmithKline

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of GSK2339345.

Cough

United Kingdom
Mayo Clinic
Takeda Pharmaceuticals International, Inc.

Completed

Biomarkers for Intestinal Permeability in Patients With Constipation

Irritable Bowel Syndrome | Intestinal Diseases | Constipation

United States
Hadassah Medical Organization

Unknown

Safety, Tolerability and Effects of Mannitol in Parkinson's Disease (PD-mannitol)

Parkinson Disease

Israel
Mundipharma AB

Completed

Mannitol Challenge Test in Adult Asthma Patients With Fixed Dose Combinations

Asthma

Sweden
University of Dundee

Completed

Steroid Titration Against Mannitol IN Asthma

Asthma
Shandong University

Unknown

Evaluation of the Performance of Two Neutral Oral Contrast Agents in CT Enterography

CTE

China
University Hospital, Grenoble

Terminated

Comparison of 2 Doses of Mannitol on Post Traumatic Intracranial Hypertension and Cerebral Monitoring

Traumatic Brain Injury | Intracranial Hypertension

France
Ting Li
Affiliated Hospital of Armed Police Logistics College

Unknown

Multi-parameters'Change Process During Dehydration Therapy on Brain Edema Patients.

Intracranial Pressure Increase | Hemodynamic Instability | Water on the Brain
Boehringer Ingelheim

Completed

The OPTI Study in Spain Looks at the History Flare-ups in Patients With Chronic Obstructive Pulmonary Disease (COPD) Treated With Inhaled Steroids.

Pulmonary Disease, Chronic Obstructive

Spain
Pearl Therapeutics, Inc.

Completed

Phase I Study Evaluating the Safety and Pharmacokinetics of Budesonide, Glycopyrronium, and Formoterol Fumarate Inhalation Aerosol (BGF MDI) in Healthy Volunteers

Healthy Volunteers

United States
Liquidia Technologies, Inc.
Nuventra, Inc.

Completed

Investigation of the Safety and Pharmacology of Dry Powder Inhalation of Treprostinil (INSPIRE)

Primary Pulmonary Hypertension

United States
National Heart, Lung, and Blood Institute (NHLBI)
Childhood Asthma Research and Education Network

Completed

Prevention of Early Asthma in Kids (PEAK)

Lung Diseases | Asthma
Liquidia Technologies, Inc.
Nuventra, Inc.

Active, not recruiting

Extension Study for Participants in LIQ861 Trials to Evaluate the Long-term Safety of Dry Powder Inhalation of Treprostinil

Primary Pulmonary Hypertension

United States
Centre Hospitalier Universitaire de Besancon

Completed

Sodium Lactate and Brain Relaxation (LSD) (LSD)

Intracranial Hypertension | Sodium Lactate | Brain Relaxation

France
Alexza Pharmaceuticals, Inc.

Completed

Staccato Prochlorperazine in Migraine (Out Patient)

Migraine Headache | Aura

United States
Ajou University School of Medicine
AstraZeneca

Recruiting

Long-term Effect of Steroid on Metabolic Diseases in Asthmatics

Asthma | Osteoporosis Risk | Osteoporotic Fractures | Osteoporosis, Osteopenia

Korea, Republic of
GlaxoSmithKline

Completed

WEUKBRE5554: IMI PROTECT(Work Package 2): Beta2 Agonists and Acute Myocardial Infarction

Asthma
Massachusetts General Hospital
Rezoagli, Emanuele, M.D., Massachusetts General Hospital, Harvard Medical... and other collaborators

Active, not recruiting

Prolonged Hypoxic Breathing in Healthy Volunteers: a Safety Study (MGH-nitrogen)

Healthy Volunteers

United States
Syral
Beghin-Meiji

Completed

Digestive Tolerance of Maltitol and FOS

Digestive Tolerance in Healthy Adults

France

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