Search clinical trials for: Irinotecan

Total 1395 results

National Cancer Center, Korea

Unknown

Preoperative Chemoradiotherapy With Cetuximab in Rectal Cancer (ERBIRIX)

Rectal Neoplasms | Neoadjuvant Treatment

Korea, Republic of
Luye Pharma Group Ltd.

Enrolling by invitation

Safety, Tolerability, Pharmacokinetics (PK), and Primary Clinical Efficacy of LY01616 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

China
Qingdao Central Hospital

Completed

Study of Irinotecan,Oxaliplatin, and S1 in Patients With Advanced Pancreatic Cancer

Overall Survival

China
Southwest Oncology Group
National Cancer Institute (NCI); Cancer and Leukemia Group B; North Central Cancer...

Completed

S0124: Cisplatin Combined With Irinotecan or Etoposide For Extensive-Stage Small Cell Lung Cancer

Lung Cancer

United States, Canada
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Terminated

Irinotecan and Cediranib in Treating Patients With Metastatic Colorectal Cancer That Did Not Respond to Previous Oxaliplatin, Fluoropyrimidine, and Bevacizumab

Colorectal Cancer

United States
Hans-Joachim Schmoll, MD
Biocompatibles UK Ltd

Terminated

TACE With Irinotecan Drug-eluting Beads and Intravenous (IV) Cetuximab in Refractory Colorectal Cancer (DEBIRITUX)

Colorectal Cancer

Germany
University of New Mexico

Completed

Phase I Study of Capecitabine in Combination With Cisplatin and Irinotecan

Cancer | Solid Tumors

United States
Kuirong Jiang
CSPC Ouyi Pharmaceutical Co., Ltd.

Recruiting

Irinotecan Liposome Combined With Oxaliplatin and Tegafur as Adjuvant Therapy for Pancreatic Cancer

Pancreatic Cancer | Adjuvant Therapy

China
Australian & New Zealand Children's Haematology...
The Hospital for Sick Children; Kazia Therapeutics Limited; Day One Biopharmaceuticals... and other collaborators

Not yet recruiting

Optimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent Cancer

Childhood Cancer | Refractory Cancer | Recurrent Cancer | Childhood Solid Tumor | Childhood Brain Tumor

Australia, Canada
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Irinotecan and Docetaxel in Treating Patients With Metastatic or Locally Recurrent Head and Neck Cancer

Head and Neck Cancer

United States
Brown University
Rhode Island Hospital; Merrimack Pharmaceuticals

Terminated

BrUOG 329 Onivyde & Metronomic Temozolomide in Recurrent Glioblastoma (329)

Glioblastoma | Glioblastoma Multiforme | GBM

United States
Fox Chase Cancer Center

Terminated

Chemoembolization Using Irinotecan in Treating Patients With Liver Metastases From Metastatic Colon or Rectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Liver Metastases | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
University of Washington
National Cancer Institute (NCI)

Completed

Surgery With or Without Radiofrequency Ablation Followed by Irinotecan in Treating Patients With Colorectal Cancer That is Metastatic to the Liver

Colorectal Cancer | Metastatic Cancer

United States, Canada
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Irinotecan Plus Radiation Therapy Followed By Chemotherapy in Treating Patients With Glioblastoma Multiforme

Brain and Central Nervous System Tumors
Hallym University Medical Center
Pfizer; HK inno.N Corporation; Handok Inc.; Jeil Pharmaceutical Co., Ltd.

Completed

S-1, Oxaliplatin, and Irinotecan for Advanced Gastrointestinal Cancer

Gastrointestinal Neoplasms

Korea, Republic of
University of Alabama at Birmingham
National Cancer Institute (NCI)

Completed

Cetuximab and Irinotecan in Treating Patients With Advanced Colorectal Cancer

Colorectal Cancer
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
National Cancer Institute (NCI)

Completed

Phase II Study of Oxaliplatin, Irinotecan, and Capecitabine in Advanced Gastric/Gastroesophageal Junction Carcinoma

Adenocarcinoma of the Gastroesophageal Junction | Stage IV Gastric Cancer | Recurrent Gastric Cancer | Diffuse Adenocarcinoma of the Stomach | Intestinal Adenocarcinoma of the Stomach | Mixed Adenocarcinoma of the Stomach | Stage IIIA Gastric Cancer | Stage IIIB Gastric Cancer | Stage IIIC Gastric Cancer

United States
Peking University

Terminated

Study to Compare Irinotecan Combined With Cisplatin (IP) Versus Etoposide Combined With Cisplatin (EP) in Advanced and Metastatic Gastrointestinal Pancreatic and Esophageal Neuroendocrine Carcinoma

Neuroendocrine Carcinoma

China
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Irinotecan Plus Raltitrexed in Treating Patients With Refractory Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Irinotecan, Radiation Therapy, and Docetaxel With or Without Cisplatin in Treating Patients With Locally Advanced Esophageal Cancer

Esophageal Cancer

United States
Sanofi

Completed

Phase 1/1b Dose Escalation Study Evaluating BSI-201 as a Single Agent and in Combination With Irinotecan in Subjects With Advanced Solid Tumors

Tumors

United States
St. Jude Children's Research Hospital
National Cancer Institute (NCI)

Completed

Irinotecan Followed by Radiation Therapy and Temozolomide in Treating Children With Newly Diagnosed Brain Tumor

Brain and Central Nervous System Tumors

United States
Georgetown University
National Cancer Institute (NCI)

Completed

Epirubicin Plus Irinotecan in Treating Patients With Advanced Cancer

Unspecified Adult Solid Tumor, Protocol Specific

United States
Yale University
National Cancer Institute (NCI)

Completed

Paclitaxel and Irinotecan in Treating Patients With Advanced Non-small Cell Lung Cancer

Lung Cancer

United States
National Health Research Institutes, Taiwan
China Medical University Hospital; Chang Gung Memorial Hospital; Kaohsiung Medical... and other collaborators

Not yet recruiting

Nal-IRI (ONIVYDE® ) and Carboplatin in Patients With Advanced or Metastatic GEP-NET

GEP-NET

Taiwan
AIO-Studien-gGmbH
Servier Deutschland GmbH; Crolll Gmbh

Active, not recruiting

2nd-line Therapy With Nal-IRI After Gem/Nab-pac in Advanced Pancreatic Cancer - Predictive Role of 1st-line Therapy (PREDICT)

Metastatic Pancreatic Cancer | Locally Advanced Pancreatic Cancer

Germany
Beth Israel Medical Center
St. Luke's-Roosevelt Hospital Center

Terminated

Neoadjuvant CAPOXIRI Chemotherapy in the Treatment of Pancreatic Adenocarcinoma Protocol

Metastatic Pancreatic Adenocarcinoma

United States
AHS Cancer Control Alberta
Sanofi

Completed

First Line Study of Irinotecan, Capecitabine and Oxaliplatin in Metastatic Gastric or Gastroesophageal Cancer. (IXOGoo1)

Gastric Adenocarcinoma | Gastrointestinal Neoplasm

Canada
New Mexico Cancer Care Alliance

Completed

Combination of Irinotecan, Oxaliplatin and Cetuximab for Locally Advanced or Metastatic Pancreatic Cancer

Pancreatic Cancer

United States
Swiss Group for Clinical Cancer Research

Completed

Oxaliplatin, Irinotecan, and Capecitabine in Treating Patients With Advanced or Metastatic Colorectal Cancer That Cannot Be Removed By Surgery

Colorectal Cancer

Switzerland
Onconova Therapeutics, Inc.

Completed

Safety Study of ON 01910.Na in Combination With Irinotecan or Oxaliplatin

Advanced Solid Tumors

United States
Hebei Medical University Fourth Hospital

Not yet recruiting

Neoadjuvant Chemoradiation With Nal-IRI and Capecitabine Guided by UGT1A1 Status in Patients With Rectal Cancer

Rectal Cancer
Sun Yat-sen University

Recruiting

Regorafenib Combined With Irinotecan Drug-Eluting Beads for Colorectal Cancer Liver Metastases (RIDER)

Colorectal Cancer Liver Metastases | Regorafenib

China
Mayo Clinic
National Comprehensive Cancer Network

Completed

Trifluridine/Tipiracil and Irinotecan for the Treatment of Advanced Refractory Biliary Tract Cancer

Stage III Gallbladder Cancer AJCC v8 | Stage IIIA Gallbladder Cancer AJCC v8 | Stage IIIB Gallbladder Cancer AJCC v8 | Refractory Gallbladder Carcinoma | Stage IV Gallbladder Cancer AJCC v8 | Stage IV Distal Bile Duct Cancer AJCC v8 | Stage IV Intrahepatic Bile Duct Cancer AJCC v8 | Stage IVB Gallbladder... and other conditions

United States
Johns Hopkins All Children's Hospital
The V Foundation; Brain Tumor Alliance

Completed

Study of Irinotecan and Bevacizumab With Temozolomide in Refractory/Relapsed Central Nervous System (CNS) Tumors

Central Nervous System Tumors

United States
Zhejiang University

Not yet recruiting

Irinotecan Liposome for Resectable Pancreatic Cancer With or Without Addebelizumab (CAPT-02)

Resectable Pancreatic Cancer | Neoadjuvant Chemotherapy
Tianjin Medical University Cancer Institute and...
CSPC Ouyi Pharmaceutical Co., Ltd.

Recruiting

Efficacy and Safety of Irinotecan Liposome Injection Combined With 5-FU/LV± Immunotherapy in First-line Gemsitabine + Immunoprogressive Patients With Metastatic Biliary Tract Cancer

Metastatic Biliary Tract Cancer

China
Sun Yat-sen University
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

Doxorubicin Hydrochloride Liposome Combined With Irinotecan Versus VIT Regimen in the Treatment of Pediatric Rhabdomyosarcoma

Rhabdomyosarcoma, Child
National Cancer Institute (NCI)

Completed

Irinotecan and Cisplatin With or Without Amifostine in Treating Children With Solid Tumors That Have Not Responded to Previous Therapy

Unspecified Childhood Solid Tumor, Protocol Specific

United States
University of Toyama

Unknown

Feasibility Study of CDDP + CPT-11 + PSK for Extensive-Stage Disease (ED) Small Cell Lung Cancer (RNCLC)

Small Cell Lung Cancer

Japan
Tianjin Medical University Cancer Institute and...
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

Efficacy and Safety of Anlotinib, Irinotecan and Temozolomide in the Treatment of Refractory or Recurrent Neuroblastoma in Children: an Open, Single Arm, Single Center, Phase II Clinical Study

Refractory or Recurrent Neuroblastoma in Children
Abramson Cancer Center of the University of Pennsylvania
National Cancer Institute (NCI)

Completed

Irinotecan Plus ICI D1694 in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Cisplatin, Irinotecan, and Radiation Therapy in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer That Can Be Removed By Surgery

Esophageal Cancer

United States
Technical University of Munich

Unknown

Trabectedin and Irinotecan for Refractory Pediatric Sarcomas (TrIPReSarc)

Recurrent Ewing Sarcoma | Recurrent Rhabdomyosarcoma | Recurrent Childhood Soft Tissue Sarcoma
Seoul National University Hospital

Completed

Paclitaxel and Irinotecan in Advanced Gastric Cancer (TI-2ndAGC)

Advanced Gastric Cancer

Korea, Republic of
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy, Temozolomide, and Irinotecan in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)

Completed

Irinotecan Hydrochloride With or Without Alvocidib in Treating Patients With Advanced Stomach or Gastroesophageal Junction Cancer That Cannot Be Removed By Surgery

Adenocarcinoma of the Gastroesophageal Junction | Stage IV Gastric Cancer | Recurrent Gastric Cancer | Diffuse Adenocarcinoma of the Stomach | Intestinal Adenocarcinoma of the Stomach | Mixed Adenocarcinoma of the Stomach | Stage IIIA Gastric Cancer | Stage IIIB Gastric Cancer | Stage IIIC Gastric Cancer

United States
Symphogen A/S

Active, not recruiting

Sym021 in Combination With Either Sym022 or Sym023 or Sym023 and Irinotecan in Patients With Recurrent Advanced Selected Solid Tumor Malignancies

Solid Tumor | Metastatic Cancer

United States, Canada, France, Spain
Jonsson Comprehensive Cancer Center

Completed

Irinotecan and Paclitaxel in Treating Patients With Metastatic or Recurrent Cancer of the Esophagus or Stomach

Gastric Cancer | Esophageal Cancer

United States

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