Search clinical trials for: Isotretinoin

Total 159 results

Y-mAbs Therapeutics

Withdrawn

Naxitamab and Granulocyte-Macrophage Colony Stimulating Factor (GMCSF) and Isotretinoin for Consolidation of Patients With High-Risk Neuroblastoma in First Remission.

Neuroblastoma

Korea, Republic of, Singapore, Hong Kong, Russian Federation
Bayer

Completed

Evaluation of Patient and Physician Reported Reasons for Switching Factor VIII Replacement Therapies (PARkER)

Hemophilia A

United States
Memorial Sloan Kettering Cancer Center

Completed

Anti-GD2 3F8 Monoclonal Antibody and GM-CSF for High-Risk Neuroblastoma

Neuroblastoma

United States
Federal University of São Paulo

Unknown

Efficacy and Safety of Low-dose Oral Isotretinoin for Seborrhea

Quality of Life | Seborrheic Dermatitis | Seborrhea

Brazil
Zagazig University

Recruiting

Oral Isotretinoin in Melasma a Randomized Controlled Trial

Melasma

Egypt
National Cancer Institute (NCI)

Terminated

Vorinostat and Isotretinoin in Treating Patients With Advanced Kidney Cancer

Stage III Renal Cell Cancer | Stage IV Renal Cell Cancer | Recurrent Renal Cell Cancer

United States
National Cancer Institute (NCI)

Completed

MS-275 and Isotretinoin in Treating Patients With Metastatic or Advanced Solid Tumors or Lymphomas

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Effect of Isotretinoin on Immune Activation Among HIV-1 Infected Subjects With Incomplete CD4+ T Cell Recovery

HIV-1 Infection

United States, Puerto Rico
National Cancer Institute (NCI)

Completed

Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia

Unspecified Childhood Solid Tumor, Protocol Specific | Juvenile Myelomonocytic Leukemia | Recurrent Childhood Medulloblastoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Childhood Acute Promyelocytic Leukemia (M3) | Childhood Chronic Myelogenous Leukemia | Recurrent Childhood Acute Lymphoblastic... and other conditions

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biological Therapy, Sargramostim, and Isotretinoin in Treating Patients With Relapsed or Refractory Neuroblastoma

Recurrent Neuroblastoma

United States, Canada
University of Aberdeen

Completed

A Pilot Study of the Effects of Isotretinoin on Cognition, Learning and Memory

Acne Vulgaris

United Kingdom
University of California, Davis

Completed

De Novo Lipogenesis of Sebaceous Glands in Acne

Acne Vulgaris

United States
Lady Davis Institute

Recruiting

Doxycycline vs Isotretinoin for Acneiform Eruptions of TKI

Acneiform Eruptions | Cancer, Treatment-Related

Canada
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Isotretinoin Plus Dexamethasone in Treating Patients With Multiple Myeloma

Multiple Myeloma and Plasma Cell Neoplasm

United States
University of Colorado, Denver

Completed

13-Cis Retinoic Acid With or Without Vitamin E for Prevention of Lung Cancer (13-Cis)

Lung Cancer | Drug Toxicity

United States
Universidade Federal de Goias
Conselho Nacional de Desenvolvimento Científico e Tecnológico; Germed Pharma; Theraski...

Completed

Oral Isotretinoin Versus Topical Tretinoin for Actinic Keratosis (ARISOAK)

Actinic Keratosis

Brazil
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Therapy Plus Etoposide in Treating Patients With Neuroblastoma

Neuroblastoma

United States
Eastern Cooperative Oncology Group

Completed

Double Blind Phase III Trial of Effects of Low Dose 13-Cisretinoic Acid on Prevention of Second Primaries in Stages I-II Head and Neck Cancer

Stage I-II Head and Neck Cancer
M.D. Anderson Cancer Center

Completed

Phase II Study Of Roferon and Accutane For Patients With T-Cell Malignancies

Hematologic Neoplasms | Lymphoma, T-Cell | Mycosis Fungoides

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

Erlotinib Hydrochloride and Isotretinoin in Treating Patients With Recurrent Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Oligodendroglioma | Recurrent Adult Brain Tumor

United States
Kafrelsheikh University

Unknown

Efficacy and Safety of Drug Combination Therapy of Isotretinoin and Some Antifungal Drugs as A Potential Aerosol Therapy for COVID-19 : An Innovative Therapeutic Approach COVID-19 (Isotretinoin)

Covid19

Egypt
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Procarbazine and Isotretinoin in Treating Patients With Recurrent Primary Malignant Gliomas

Brain and Central Nervous System Tumors
University Hospital, Gentofte, Copenhagen

Completed

Single Dose of 9-cis-retinoic Acid in Hepatic Patients

Hepatic Insufficiency

Denmark
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Isotretinoin, Interferon Alfa, and Vitamin E in Treating Patients With Stage III or Stage IV Head and Neck Cancer

Head and Neck Cancer

United States, Australia, South Africa, Peru, Puerto Rico
Memorial Sloan Kettering Cancer Center

Terminated

3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Consolidation of Second or Greater Remission of High-Risk Neuroblastoma

Neuroblastoma

United States
Memorial Sloan Kettering Cancer Center

Completed

3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Consolidation of First Remission After Non-Myeloablative Therapy in Patients With High-Risk Neuroblastoma

Neuroblastoma

United States
University of Medicine and Dentistry of New Jersey
National Cancer Institute (NCI)

Terminated

Isotretinoin, Interferon Alpha-2b, and Paclitaxel in Stage IV, Recurrent, or Persistent Cervical Cancer

Cervical Cancer

United States
National Cancer Institute (NCI)

Completed

A Phase I Trial of Tamoxifen and 9-Cis-Retinoic Acid in Breast Cancer Patients

Breast Cancer | Breast Neoplasm

United States
Nova Laboratories Limited

Completed

Oral Liquid 13-cis-retinoic Acid (13-CRA) (My-CRA)

Neuroblastoma

United Kingdom
University of Iowa
Molecular Insight Pharmaceuticals, Inc.

Withdrawn

90Y DOTA/Retinoic Acid for Neuroblastoma and Neuroendocrine Tumor (NET)

Neuroendocrine Tumor | Neuroblastoma

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Feasibility of Retinoic Acid Treatment in Emphysema (FORTE)

Lung Diseases | Lung Diseases, Obstructive | Chronic Obstructive Pulmonary Disease | Emphysema
Edward Lain, MD
Vyne Therapeutics Inc.

Completed

A Companion Treatment Study for Patients With Moderate to Severe Acne Vulgaris

Acne Vulgaris

United States
European Organisation for Research and Treatment...

Completed

Docetaxel With or Without Oblimersen in Treating Patients With Hormone-Refractory Adenocarcinoma (Cancer) of the Prostate

Prostate Cancer

Belgium, Poland, Italy, Austria, France, Denmark, Netherlands, United Kingdom, Israel, Spain, Portugal
M.D. Anderson Cancer Center
AstraZeneca

Terminated

ZD6474 Alone and in Combination With Retinoic Acid in Pediatric Neuroblastoma

Neuroblastoma

United States
Zagazig University

Completed

Combined Low-Dose Isotretenion and Long-Pulsed 1064 ND-YAG Laser in the Treatment of Acne Erythema

Acne Vulgaris

Egypt
University of New Mexico
National Cancer Institute (NCI)

Completed

Biological Therapy Plus Chemotherapy in Treating Patients With Metastatic or Recurrent Kidney Cancer

Kidney Cancer

United States
BeiGene

Completed

Evaluation of the Safety and Pharmacokinetics of Dinutuximab Beta as Maintenance Therapy in Chinese Patients With High-risk Neuroblastoma

High-risk Neuroblastoma

China
Kafrelsheikh University
Damietta University

Unknown

Aerosol Combination Therapy of All-trans Retinoic Acid and Isotretinoin as A Novel Treatment for Inducing Neutralizing Antibodies in COVID -19 Infected Patients Better Than Vaccine : An Innovative Treatment (Antibodies)

COVID-19
Medical University of South Carolina

Not yet recruiting

Weekly Isotretinoin vs Tetracycline for Moderate Acne

Acne Vulgaris
Kafrelsheikh University

Not yet recruiting

Combination of Recombinant Bacterial ACE2 Receptors -Like Enzyme of B38-CAP and Isotretinoin Could be Promising Treatment for COVID-19 Infection- and Its Inflammatory Complications

COVID
University of Medicine and Dentistry of New Jersey
National Cancer Institute (NCI)

Terminated

Isotretinoin, Interferon Alfa-2b, Docetaxel, and Estramustine in Treating Patients With Metastatic Prostate Cancer That Did Not Respond to Hormone Therapy

Prostate Cancer

United States
University of Cologne

Terminated

NB2013-HR German (GPOH) / Dutch (DCOG) Trial (NB2013-HR)

Neuroblastoma

Germany
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche

Completed

Chemoprevention of Anal Neoplasia Arising Secondary to Anogenital Human Papillomavirus Infection in Persons With HIV Infection.

HIV Infections | Anus Neoplasms

United States
Memorial Sloan Kettering Cancer Center

Completed

High-Dose 3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Consolidation of First Remission After Myeloablative Therapy and Autologous Stem-Cell Transplantation

Neuroblastoma

United States
Masonic Cancer Center, University of Minnesota

Completed

High Dose Chemotherapy and Autologous Transplant for Neuroblastoma

Neuroblastoma

United States
Marmara University

Recruiting

The Effects of Systemic Isotretinoin Treatment on Adrenal Steroid and Sex Hormones Level in Severe Acne Vulgaris

Acne Vulgaris

Turkey
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Therapy With Sargramostim and Interleukin-2 in Treating Children With Neuroblastoma

Recurrent Neuroblastoma | Disseminated Neuroblastoma | Regional Neuroblastoma

United States
National Cancer Institute (NCI)

Completed

Belinostat and Isotretinoin in Treating Patients With Solid Tumors That Are Metastatic or That Cannot Be Removed by Surgery

Adult Solid Neoplasm

United States
Galderma R&D

Completed

Efficacy & Safety Comparison of Epiduo With Doxycycline Versus Vehicle With Isotretinoin in the Treatment of Severe Acne (POWER)

Acne

Canada
University of Pennsylvania
Gilead Sciences

Recruiting

CART-EGFR-IL13Ra2 in EGFR Amplified Recurrent GBM

Glioblastoma

United States

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