Search clinical trials for: Ketamine and Org 25935

Total 5808 results

Merck Sharp & Dohme LLC

Terminated

Org 25935 Versus Placebo as Augmentation to Cognitive-behavioral Therapy to Treat Panic Disorder (P05705)

Panic Disorder
Merck Sharp & Dohme LLC

Completed

Adjuvant Treatment With a Glycine Uptake Inhibitor in Participants With Negative Symptoms of Schizophrenia (P05695) (MK-8435-001) (GIANT)

Schizophrenia
Yale University
Organon

Completed

Pilot Study of ORG 25935 Modulation of Ketamine-induced Behavioral and Cognitive Effects in Healthy Male Subjects

Healthy

United States
Merck Sharp & Dohme LLC

Terminated

Trial Investigating the Efficacy and Safety of SCH 900435 (Org 25935) in Relapse Prevention in Participants With Alcohol Dependence (P05718) (OD-H)

Alcoholism
University of Plymouth
Veeda Clinical Research; Organon Teknika

Completed

First Administration to Man Of Org 25435 a New Intravenous Anesthetic

Anaesthesia

United Kingdom
Medical University of Vienna

Recruiting

Imaging Neural Correlates of Ketamine Using PET/MR (RSKet)

Major Depressive Disorder

Austria
Erasmus Medical Center

Enrolling by invitation

Long-term Pain Modulation by Intravenous Esketamine in CRPS (KetCRPS-2)

Complex Regional Pain Syndromes | CRPS (Complex Regional Pain Syndromes)

Netherlands
Juvenile Bipolar Research Foundation

Terminated

Intranasal Ketamine In the Treatment of Pediatric Bipolar Disorder (IKBP)

Bipolar Disorder

United States
Janssen Research & Development, LLC

Completed

Crossover Study to Evaluate the Abuse Potential of Intranasal Esketamine Compared to Racemic Intravenous Ketamine in Nondependent, Recreational Drug Users

Drug Abuse

United States
Tianjin Medical University General Hospital

Recruiting

S-ketamine Prevents Postoperative Pain and Cognitive Dysfunction After Tibial Fracture

Postoperative Pain | Postoperative Cognitive Dysfunction

China
Fujian Provincial Hospital

Completed

Esketamine-propofol Versus Propofol for Flexible Bronchoscopy

Postoperative Recovery

China
Turku University Hospital
University of Turku; University of Helsinki

Completed

Dose-response of Ketamine in Patient Controlled Analgesia in Orthopaedic Surgery Patients (DoseRespKeta)

Pain, Postoperative

Finland
Eye & ENT Hospital of Fudan University

Completed

S-ketamin Premedication in Pediatric EENT Surgery

Pain, Procedural | Emotions | Separation Anxiety

China
The George Institute
The University of New South Wales

Not yet recruiting

Comparative Effectiveness Study of Two Forms of Ketamine for Treatment-resistant Depression (TREK)

Treatment Resistant Depression

Australia
Second Affiliated Hospital, School of Medicine,...

Recruiting

Intraoperative S-ketamine to Prevent Postoperative Hyperalgesia in Patients Undergoing Video-assisted Thoracic Surgery

Postoperative Hyperalgesia

China
Beijing Obstetrics and Gynecology Hospital
Obstetrics & Gynecology Hospital of Fudan University; Beijing Haidian Maternal... and other collaborators

Unknown

The Efficacy and Safety of S-ketamine in Elective Cesarean Section (ES-CS)

Depression | Analgesia | Cesarean Section | Anesthesia | Parturition
Yan Qiu

Unknown

The Effect of S-ketamine for Patients Undergoing Electroconvulsive Therapy (ECT) (ECT)

Major Depressive Disorder | Depression, Unipolar | Depression, Bipolar | Manic-Depressive - Now Depressed

China
Zylorion Health

Withdrawn

Repeated Intranasal Esketamine Plus Almond Therapy in Participants With Treatment Resistant Depressive Disorder - 3 Month Extension Study (ZYL-730-02)

Treatment Resistant Major Depressive Disorder
Lund University

Completed

Racemic Ketamine Versus S-ketamine With Arterial Spin Labeling (ASL)-MRI in Healthy Volunteers

Healthy | Abnormal Vascular Flow

Sweden
Centre Hospitalier Universitaire de Charleroi
Centre Hospitalier Universitaire de Liege

Recruiting

Comparison of Ketamine and Esketamine in Patients Suffering From Fibromyalgia Syndrome. (KESK-FIQ)

Fibromyalgia

Belgium
Zylorion Health

Terminated

Repeated Intranasal Esketamine Plus Almond Therapy in Patients With Treatment Resistant Depression (ZYL-730-01)

Treatment Resistant Major Depressive Disorder

Canada
Dr. Inge Winter
Universität Münster

Not yet recruiting

The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. (INTENSIFY MDD)

Major Depressive Disorder | Treatment Resistant Depression

Austria, Italy, Germany, Spain, United Kingdom
Eye & ENT Hospital of Fudan University

Recruiting

Comparison of Esketamine-Propofol and Fentanyl-Propofol

Hemodynamics

China
Peking University First Hospital
Peking University International Hospital; Women's Hospital School Of Medicine... and other collaborators

Completed

Low-dose S-Ketamine and Postpartum Depression in Parturients With Prenatal Depression

Postpartum Depression | Ketamine | Prenatal Depression

China
Peking University First Hospital
Peking University International Hospital; Women's Hospital School Of Medicine... and other collaborators

Completed

Low-dose S-ketamine in Women With Prenatal Depression

Postpartum Depression | Ketamine | Prenatal Depression

China
Chinese PLA General Hospital
First Affiliated Hospital, Sun Yat-Sen University; Shengjing Hospital; First... and other collaborators

Not yet recruiting

Safety and Efficacy Evaluation of S (+) - Ketamine in Adults

Postoperative Pain | Anesthesia | Adults
Chinese PLA General Hospital
Shanghai Children's Medical Center; Beijing Children's Hospital; Southern Medical... and other collaborators

Enrolling by invitation

Safety and Efficacy Evaluation of S (+) - Ketamine in Children

Delirium | Postoperative Pain | Analgesia | Children | Acute Pain | Depression, Anxiety | Hyperalgesia | S-ketamine | Esketamine

China
Psych Atlanta

Completed

Intranasal Esketamine to Maintain the Antidepressant Response to IV Racemic Ketamine

Treatment Resistant Depression

United States
The Second Hospital of Anhui Medical University

Recruiting

Effect of Intravenous S-ketamine on Opioid Consumption

Breast Cancer Surgery

China
Merck Sharp & Dohme LLC

Withdrawn

Efficacy & Safety of SCH 900435 in Schizophrenia (Study P06079)(WITHDRAWN) (GUEST)

Schizophrenia
Grace Lim, MD, MS
National Institute of Mental Health (NIMH)

Recruiting

Ketamine Tolerated Dose for Postpartum Depression and Pain After Cesarean Delivery

Pain, Postoperative | Depression, Postpartum

United States
Janssen Research & Development, LLC

Completed

A Study to Investigate the Different Modes of (S) Ketamine Administration in Healthy Participants

Healthy

Belgium
Medical University of Vienna

Unknown

Positron Emission Tomography Assessment of Ketamine Binding of the Serotonin Transporter

Depression | Ketamine

Austria
Wuhan Union Hospital, China

Not yet recruiting

Prophylactic Effects of Esketamine in Surgical Patients

Surgical Injury

China
Universidade Federal de Goias

Completed

Sevoflurane Associated With Oral Midazolam and Ketamine for Dental Sedation

Dental Anxiety

Brazil
Grand Hôpital de Charleroi

Recruiting

ESKETamine for FIBromyalgia Treatment (ESKEFIB)

Fibromyalgia

Belgium
Assistance Publique - Hôpitaux de Paris

Completed

Ketamine Associated With Morphine PCA After Total Hip Arthroplasty (KETAMINE)

Arthroplasty, Replacement, Hip

France
Elina Brinck

Not yet recruiting

KetaMoHydBup: Pharmacokinetic Interaction of S-ketamine, Morphine, Hydromorphone and Buprenorphine (KetaMoHydBup)

The Effect of S-ketamine on Pharmacokinetics of Morphine, Hydromorphone, and Buprenorphine
Anshi Wu

Recruiting

Intravenous Esketamine on Prevention of Postoperative Depression in Patients Undergoing Cardiac Surgery

Postoperative Depression

China
Peking University First Hospital

Recruiting

Analgesic Effects of Low-dose S-ketamine in Major Spine Fusion Surgery

Spine Fusion | Postoperative Analgesia | S-ketamine

China
Beijing Tiantan Hospital

Unknown

Effects of Small-dose S-ketamine on Anesthesia-induced Atelectasis in Anesthetized Patients Accessed by Pulmonary Ultrasound

Atelectasis
Peking University First Hospital

Recruiting

General Anesthetics-related Changes in Prefrontal EEG During Pediatric Surgical Anesthesia

Electroencephalogram | General Anesthetic

China
Ullevaal University Hospital
University of Oslo

Completed

Ketamine on Acute Pain in Females and Males

Tooth, Impacted | Mouth and Tooth Diseases

Norway
Rigshospitalet, Denmark
Copenhagen Trial Unit, Center for Clinical Intervention Research

Recruiting

The Anesthetic Ketamine as Treatment for Patients With Severe Acute Brain Injury (KETA-BID)

Traumatic Brain Injury | Subarachnoid Hemorrhage, Aneurysmal | Intracerebral Hemorrhage

Denmark
Tianjin Nankai Hospital

Recruiting

Effect of S-ketamine Anesthetic on Inflammatory Response in Septic Patients Undergoing Abdominal Surgery

Sepsis | Acute Lung Injury

China
Medical University of Graz

Completed

The Preemptive Analgetic Potency of Low Dose S-Ketamine (Miniket)

Pain

Austria
Assiut University

Completed

Comparing Three Different Doses of Intrathecal Ketamine

Ketamine Causing Adverse Effects in Therapeutic Use

Egypt
Ling Dong

Recruiting

The Effect of S-ketamine Combined With Sufentanil for Postoperative Analgesia in Patients Following Cesarean Section

Cesarean Section | S-ketamine | Analgesia, Patient-Controlled

China
Tao Zhang

Recruiting

Analgesic Effects of Caudal S-ketamine for Supplementation of Ropivacaine Caudal Analgesia in Children With Hypospadias

Hypospadias | Caudal Block | Pediatrics | Postoperative Analgesia | S-ketamine

China
The Second Affiliated Hospital of Chongqing Medical...

Completed

Effect of S-ketamine in Cesarean Section Combined Anesthesia

Postoperative Pain

China

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