Search clinical trials for: LMT (atorvastatin, simvastatin, or rosuvastatin)

Total 245 results

Regeneron Pharmaceuticals
Sanofi

Completed

Study of Alirocumab (REGN727/SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy) (ODYSSEY FH II)

Heterozygous Familial Hypercholesterolemia

United Kingdom, Netherlands, Czech Republic, Norway
Organon and Co

Completed

Ezetimibe/Simvastatin (MK-0653A) Versus Rosuvastatin Versus Doubling Statin Dose in Participants With Cardiovascular Disease and Diabetes Mellitus (MK-0653A-133)(COMPLETED)

Diabetes Mellitus | Cardiovascular Disorder
Organon and Co

Completed

A Study to Determine the Number of Patients Who Reach Optimal Cholesterol Levels on Each of Three Different Treatments (0653A-121)

Hypercholesterolemia
Canadian Network for Observational Drug Effect...
Canadian Institutes of Health Research (CIHR); Drug Safety and Effectiveness...

Completed

High Potency Statins and the Risk of Diabetes (Statins-DM)

Cardiovascular Disease | Diabetes Mellitus, Type 2
Canadian Network for Observational Drug Effect...
Canadian Institutes of Health Research (CIHR); Drug Safety and Effectiveness...

Completed

High Potency Statins and Acute Kidney Injury

Hypercholesterolemia

Canada
Wenzhou Medical University

Terminated

The Therapeutic Effects of Statins and Berberine on the Hyperlipemia

Dyslipidemias

China
AstraZeneca

Completed

Assessment of the Lipid Lowering Effect of Rosuvastatin Compared to Atorvastatin in Subjects With Coronary Heart Disease

Coronary Heart Disease

Sweden
Hospital Israelita Albert Einstein
Novartis; epHealth

Completed

Real World Evidence Study of Statin Use in Brazil (RWE-Statins)

Myocardial Infarction | Cardiovascular Diseases | Stroke | Hypertension | Diabetes Mellitus | Dyslipidemias

Brazil
Organon and Co
Merck Sharp & Dohme LLC

Completed

Comparison of Ezetimibe Added to Ongoing Statin Therapy Versus Doubling the Dose of Statin in the Treatment of Hypercholesterolemia (P04355)

Hypercholesterolemia
Samsung Medical Center
Don-A Pharmaceutical, Seoul, South Korea

Unknown

Intensive Statin Treatment in Acute Ischemic Stroke Patients With INtracranial Atherosclerosis (STAMINA-MRI)

Stroke | Intracranial Atherosclerosis

Korea, Republic of
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Active, not recruiting

Investigating the Lowest Threshold of Vascular Benefits From LDL Cholesterol Lowering in Patients With Stable CV Disease (INTENSITY-HIGH)

Cardiovascular Diseases | Atherosclerosis

United Kingdom
Rockefeller University
Cornell University; Adelphi University

Terminated

Quality of Life in Patients With Statin-Associated Myopathy

Statin Adverse Reaction

United States
Organon and Co

Completed

A 12 Week Study of MK0653A in Patients Who Have Been Hospitalized for a Possible Heart Problem (0653A-808)

Hypercholesterolemia
Sunnybrook Health Sciences Centre
Merck Frosst Canada Ltd.; Schering-Plough

Terminated

INdians Followed for INtensive Lipid Lowering Treatment and Its safetY (INFINITY)

Hypercholesterolemia

Canada
Kuhnil Pharmaceutical Co., Ltd.

Completed

Efficacy and Safety of Prescription Omega-3 Fatty Acid Added to Stable Statin Therapy in Patients With Type 2 Diabetes and Hypertriglyceridemia

Diabetes Mellitus, Type 2 | Hypertriglycemia

Korea, Republic of
Sanofi
Regeneron Pharmaceuticals

Completed

Safety, Tolerability, and Effect of Alirocumab in High Cardiovascular Risk Patients With Severe Hypercholesterolemia Not Adequately Controlled With Conventional Lipid-modifying Therapies (ODYSSEY APPRISE)

Hypercholesterolemia

France, Belgium, Austria, Canada, Czechia, Denmark, Finland, Germany, Greece, Hungary, Poland, Romania, Slovakia, Slovenia, Spain, Switzerland
Eli Lilly and Company

Completed

A Study of LY3015014 in Participants With High Cholesterol

Hypercholesterolemia

Poland, Netherlands, United States, Denmark, Canada, Japan, Czechia, Puerto Rico
Novartis Pharmaceuticals

Completed

Safety, Pharmacokinetics and Pharmacodynamics of LGT209 in Healthy Volunteers With Elevated Cholesterol and in Hypercholesterolemic Patients Treated With Statins

Hypercholesterolemia | LDL Cholesterol

United States
Peking University People's Hospital

Recruiting

Progesterone Therapeutic Regimen Plus Statins in Young Women With Early Endometrial Carcinoma and Atypical Endometrial Hyperplasia

Atypical Endometrial Hyperplasia and Endometrial Carcinoma Stage I

China
Damanhour University
Tanta University

Completed

Type 2 Diabetic Patients Maintained on Statin Therapy

Dyslipidemia Associated With Type II Diabetes Mellitus

Egypt
Abbott

Completed

A Year 2, Safety Extension Study of the Combination of ABT-335 and Statin Therapy for Subjects With Mixed Dyslipidemia

Mixed Dyslipidemia

United States
GlaxoSmithKline

Completed

A Drug Interaction Study Between Simvastatin, Atorvastatin, Rosuvastatin, and GSK2248761 in Healthy Subjects.

Infection, Human Immunodeficiency Virus

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Evaluation of Alirocumab Versus Ezetimibe on Top of Statin in Asia in High Cardiovascular Risk Patients With Hypercholesterolemia (ODYSSEY EAST)

Hypercholesterolemia

China, India, Thailand
Makerere University
University of Oxford; Case Western Reserve University

Unknown

Statin Adjunct Therapy Among ART-treated Adults in Sub-Saharan Africa: Atorvastatin and Rosuvastatin Equivalence Trial (STAR)

HIV Infection
AstraZeneca

Completed

Comparing the Efficacy and Safety of Rosuvastatin With Atorvastatin and Simvastatin (SOLAR) (SOLAR)

Hypercholesterolemia
McMaster University
Canadian Cancer Society (CCS); Prostate Cancer Canada

Recruiting

A RAndomizeD Intervention for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients (RADICALPC)

Cardiovascular Disease | Prostate Cancer

United States, Canada, Australia, Brazil, Israel, Turkey, Colombia
Johns Hopkins University
National Institute on Aging (NIA)

Completed

High-Density Lipoprotein (HDL) Cholesterol Increased Plaque Stabilization in the Elderly (NIA-Plaque)

Cardiovascular Disease | Atherosclerosis

United States
AstraZeneca

Completed

Mercury II - Compare the Efficacy and Safety of Lipid Lowering Agents Atorvastatin and Simvastatin With Rosuvastatin in High Risk Subjects With Type IIa and IIb Hypercholesterolemia

Hypercholesterolemia
Baskent University

Completed

Effects of Achieving Very Low LDL-Cholesterol After Treatment With Statins on Steroidogenesis and Cognition

Cardiovascular Disease | Type 2 Diabetes Mellitus | Cognition | LDL Cholesterol
Organon and Co
Merck Shering-Plough JV Study

Completed

A Study to Assess the Cholesterol Lowering Effect of Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Elderly Patients With High Cholesterol at High or Moderately High Risk for Coronary Heart Disease (0653A-128)

Hypercholesterolemia
Abbott

Completed

Study to Evaluate the Long-Term Safety and Efficacy of ABT-335, in Combination With Three Different Statins in Subjects With Mixed Dyslipidemia.

Dyslipidemia | Coronary Heart Disease | Mixed Dyslipidemia

United States
AstraZeneca

Completed

STELLAR-Rosuvastatin vs. Atorvastatin, Pravastatin, Simvastatin Across Dose Ranges (STELLAR)

Hypercholesterolemia
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Cardiovascular Events Based On Statin Initiation In The Elderly

Dyslipidemia | Cardiovascular
Eli Lilly and Company

Completed

A Study of LY2484595 in Patients With High LDL-C or Low HDL-C

Dyslipidemia

United States, Netherlands, Germany, Denmark, Poland, United Kingdom
Organon and Co

Completed

Ezetimibe/Simvastatin (10 mg/40 mg) vs. the Doubling of Atorvastatin in High Risk Participants (MK-0653A-134 AM1)(COMPLETED)

Hypercholesterolemia
Pfizer

Completed

Atorvastatin Versus Simvastatin In The Prevention Of Coronary Heart Disease (CHD) In Patients With Known CHD (IDEAL)

Cardiovascular Diseases

Denmark, Finland, Sweden, Norway, Netherlands, Iceland
Mayo Clinic

Completed

Statin Interchange by Pharmacist Collaborative Practice Agreement (CPA)

Hypercholesterolemia

United States
Radboud University Medical Center

Completed

Short Term Statin Treatment and Endothelial Dysfunction Due to Ischemia and Reperfusion Injury

Endothelial Dysfunction | Ischemia Reperfusion Injury

Netherlands
Pfizer

Terminated

A Clinical Trial Comparing Torcetrapib/Atorvastatin to Ezetimibe/Simvastatin In Subjects With A Cholesterol Disorder.

Dyslipidemia | Hyperlipidemia

United States
Organon and Co

Completed

EASEGO Study: Doubling of Atorvastatin/Simvastatin or INEGY in Patients With Hypercholesterolemia and Coronary Artery Disease(CAD)(0653A-089)

Atherosclerosis
Chong Kun Dang Pharmaceutical

Completed

To Assess the Safety, Efficacy and Tolerability of CKD-519, Administered With HMG-CoA Reductase Inhibitors

Dyslipidemias

Australia
Organon and Co

Completed

MK0653A (Ezetimibe (+) Simvastatin) Compared to an Approved Drug (Atorvastatin) for the Treatment of High Cholesterol (0653A-051)(COMPLETED)

Hypercholesterolemia
Pfizer

Completed

A Clinical Trial Comparing Torcetrapib/Atorvastatin To Simvastatin In Subjects With High Cholesterol.

Dyslipidemia | Hypercholesterolemia | Hyperlipidemia

United States
Centre de Recherche de l'Institut Universitaire...

Completed

Evaluation of the Influence of Statins and Proton Pump Inhibitors on Clopidogrel Antiplatelet Effects (SPICE)

Coronary Artery Disease

Canada
Tobira Therapeutics, Inc.

Completed

Pharmacokinetic and Safety Study of Cenicriviroc and HMG-CoA Reductase Inhibitors, Caffeine and Digoxin

Healthy

United States
Takeda

Terminated

Efficacy of Lapaquistat Acetate Alone or Combined With High-Dose Statin Therapy in Subjects With Hypercholesterolemia

Hypercholesterolemia

United States, South Africa, Canada
Pfizer

Terminated

A Clinical Trial Comparing Torcetrapib/Atorvastatin To Simvastatin In Subjects With High Cholesterol (A5091031).

Dyslipidemia | Hypercholesterolemia | Hyperlipidemia

United States
Mitsubishi Tanabe Pharma Corporation

Completed

A Study to Investigate the Effect of MT-8554 on the Pharmacokinetics of Simvastatin and Rosuvastatin in Healthy Subjects

Healthy

United Kingdom
Seoul National University Hospital
Merck Sharp & Dohme LLC

Unknown

Study to Compare the Effect of Vytorin (Simvastatin/Ezetimibe) 10/20mg Versus Atorvastatin 20mg on ApoB/ApoA1 Ratio in Subjects With Diabetes

Type 2 Diabetes Mellitus Without Insulin Treatment

Korea, Republic of
Chinese University of Hong Kong

Completed

Genome-wide Analysis of Lipid-lowering Efficacy and Drug Level of Simvastatin and Rosuvastatin

Hypercholesterolemia

Hong Kong

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