Search clinical trials for: Lapaquistat acetate

Total 3937 results

Takeda

Terminated

Efficacy of Lapaquistat Acetate on Blood Cholesterol Levels in Treating Subjects With Hypercholesterolemia

Hypercholesterolemia

Ukraine, Spain, Israel, Netherlands, Estonia, Russian Federation, Hungary, Norway, United Kingdom, Slovakia, Latvia
Takeda

Completed

Effect of Lapaquistat Acetate on Blood Cholesterol Levels in Subjects With Elevated Cholesterol

Dyslipidemia

United States
Takeda

Completed

Safety of Lapaquistat Acetate in Subjects With Hypercholesterolemia

Hypercholesterolemia
Takeda

Terminated

Efficacy of Lapaquistat Acetate in Subjects With Hypercholesterolemia

Hypercholesterolemia

United States
Takeda

Terminated

Efficacy of Lapaquistat Acetate Co-Administered With Current Lipid-Lowering Treatment on Blood Cholesterol Levels in Subjects With Homozygous Familial Hypercholesterolemia

Hypercholesterolemia

France, United Kingdom, United States, Israel, Poland, Canada
Takeda

Completed

Efficacy of Lapaquistat Acetate Alone and With Ezetimibe in Subjects With Primary Dyslipidemia.

Hypercholesterolemia

Serbia, Estonia, Russian Federation, Latvia
Takeda

Completed

Safety and Efficacy of Lapaquistat Acetate Taken Alone and With Atorvastatin in Subjects With Primary Dyslipidemia

Dyslipidemia

United States, Germany, Argentina, Mexico, Poland, South Africa, Chile, Netherlands, Peru, Estonia, Russian Federation, Czech Republic, Hungary, Lithuania, Latvia, Slovakia, United Kingdom
Takeda

Completed

Efficacy and Safety of Lapaquistat Acetate Coadministered With Atorvastatin in Subjects With Hypercholesterolemia

Hypercholesterolemia
Takeda

Completed

Effect of Lapaquistat Acetate Combined With Fenofibrate on Blood Cholesterol Levels

Hyperlipidemias

United States, Canada
Takeda

Completed

Efficacy of Lapaquistat Acetate and Simvastatin in Subjects With Primary Dyslipidemia.

Hypercholesterolemia

Poland, United Kingdom, Germany, South Africa, Finland, Estonia, Czech Republic
Takeda

Completed

Efficacy of Lapaquistat Acetate and Atorvastatin on Blood Cholesterol Levels in Subjects With Primary Hypercholesterolemia

Hypercholesterolemia

United States
Karolinska Institutet

Completed

Hemodynamic Effects of Cold Versus Warm Fluid Bolus

Temperature Change, Body | Hypovolemia

Sweden
Takeda

Completed

Efficacy of Lapaquistat Acetate Alone or Combined With Simvastatin in Subjects With Hypercholesterolemia

Hypercholesterolemia

United States, Canada
Takeda

Completed

Efficacy of Lapaquistat Acetate Alone or Combined With Rosuvastatin in Subjects With Hypercholesterolemia

Hypercholesterolemia

United States, Canada
University Medicine Greifswald

Completed

Neurophysiology of Prophylactic Treatment in Migraine

Migraine

Germany
Joachim Zdolsek

Recruiting

Fluid Challenge and Plasma Volume, During Surgery (FC-VE)

Gynecologic Cancer | Colorectal Cancer | Colorectal Disorders | Urologic Cancer | Benign Neoplasm

Sweden
Takeda

Terminated

Efficacy of Lapaquistat Acetate Alone or Combined With High-Dose Statin Therapy in Subjects With Hypercholesterolemia

Hypercholesterolemia

United States, South Africa, Canada
Wendell Yap, MD
University of Kansas Medical Center

No longer available

Clinical Management Decisions for Recurrent Prostate Cancer Patients Based on [11C]Acetate PET Scan

Prostate Cancer

United States
Takeda

Completed

Efficacy of Lapaquistat Acetate in Subjects Currently Treated With Lipid-Lowering Therapy.

Type 2 Diabetes

United States, Poland, United Kingdom, Germany, South Africa, Finland, Estonia, Slovakia, Czech Republic
University of Michigan
National Institutes of Health (NIH)

Completed

The Impact of Zinc Supplementation on Left Ventricular Function in Nonischemic Cardiomyopathy

Heart Failure | Cardiomyopathies

United States
Uppsala University

Terminated

Effects of Restrictive Fluid Strategy on Postoperative Oliguric Pancreatic Surgery Patients

Postoperative Complications | Fluid Therapy | Fluid Overload | Pancreas Disease | Postoperative Period

Sweden
Jonsson Comprehensive Cancer Center

No longer available

C11 Sodium Acetate PET/CT Imaging of PCa

Prostate Cancer

United States
Daniel Vaena

Completed

PET Acetate for Castrate-Resistant Prostate Cancer on Chemotherapy

Prostate Cancer | Castrate Resistant Prostate Cancer

United States
Vanderbilt University Medical Center

Completed

Balanced Solutions and Plasma Electrolytes (BASE)

Critical Illness | Acidosis, Metabolic

United States
Phoenix Molecular Imaging

Completed

PET Imaging Characteristics of C11-Acetate in Patients With Recurrent Prostate Carcinoma

Prostate Cancer

United States
Repros Therapeutics Inc.

Completed

Extension of Study ZPV-200

Uterine Fibroids

United States
University of Texas Southwestern Medical Center
National Cancer Institute (NCI); Howard Hughes Medical Institute

Recruiting

An Investigation of Kidney and Urothelial Tumor Metabolism in Patients Undergoing Surgical Resection and/or Biopsy

Kidney Cancer | Renal Cell Carcinoma | Urothelial Carcinoma | Hereditary Leiomyomatosis and Renal Cell Cancer | Metastatic Urothelial Carcinoma | Chromophobe Renal Cell Carcinoma | Papillary Renal Cell Carcinoma | HLRCC | Clear Cell Carcinoma | Metastatic Kidney Cancer | Fumarate Hydratase Deficiency | Succinate...

United States
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
Istituto Di Ricerche Farmacologiche Mario Negri

Recruiting

ALBumin Italian Outcome Septic Shock-BALANCED Trial (ALBIOSS-BALANCED) (ALBIOSS-BAL)

Septic Shock

Italy
Phoenix Molecular Imaging

Withdrawn

C11-Sodium Acetate PET/CT Imaging Evaluation in Brain Glioma, Post Therapy Necrosis and Pseudo-progression

Gliomas

United States
University Hospital, Basel, Switzerland

Completed

Estimation of Kidney Function Through Combination of Renal Biomarkers in Blood and Urine of Healthy Infants and Children. (KidMaCare)

Renal Biomarkers in Children

Switzerland
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Indacaterol Acetate Delivered Via the Concept1 Inhalation Device in Children Greater or Equal to 6 and Less Than 12 Years of Age With Asthma

Asthma

South Africa, Belgium, Croatia, Turkey, Hungary, Colombia, Slovakia, Philippines, Russian Federation, Guatemala, Germany
University of Alabama at Birmingham

Not yet recruiting

Understanding the Metabolic and Functional Derangement of Primary Mitral Regurgitation: a Feasibility Study Using Carbon 11(C-11) Acetate Cardiac Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI)

Mitral Valve Regurgitation

United States
University of Pennsylvania

Terminated

11C-Acetate PET/CT Imaging As a Biomarker of Amyloid-Induced Neuroinflammation

Mild Cognitive Impairment

United States
Takeda

Terminated

Efficacy of Lapaquistat Acetate Co-Administered With Statins in Subjects With Hypercholesterolemia

Hypercholesterolemia

United States
Rigshospitalet, Denmark
University of Iceland; Octapharma

Completed

Vasculopathic Injury and Plasma as Endothelial Rescue in Septic Shock (SHOCK) Trial (VIPER-SHOCK)

Septic Shock

Denmark
Repros Therapeutics Inc.

Completed

Evaluation of Safety, Pharmacokinetics, and Efficacy of Proellex Administered Vaginally in Women With Uterine Fibroids

Uterine Fibroids

United States
Repros Therapeutics Inc.

Completed

Evaluate the Safety and PK of Proellex® in Female Patients With Impaired Hepatic Function and Healthy Adults

Impaired Liver Function

United States
Massachusetts General Hospital

Terminated

11C Acetate Imaging Post Prostatectomy

Prostate Cancer

United States
Repros Therapeutics Inc.

Withdrawn

Open-Label Extension Study to ZPE-202

Endometriosis

United States
EMD Serono

Terminated

Efficacy, Safety, and Tolerability of Plovamer Acetate (Pathway 1)

Relapsing Remitting Multiple Sclerosis

United States, Croatia, Bulgaria, Czech Republic, Italy, Mexico, Russian Federation, South Africa, Spain, Turkey, Hungary, Poland, Ukraine, Finland, United Kingdom, Greece, Serbia
Repros Therapeutics Inc.

Completed

Crossover Study of the Safety and PK Properties of Proellex®

Pharmacokinetics

United States
Repros Therapeutics Inc.

Completed

Investigate Absorption, Metabolism and Excretion of [14C}-Proellex Following Single Oral Dose in Healthy Females

ABSORPTION | METABOLISM | EXCRETION

United States
Repros Therapeutics Inc.

Withdrawn

Safety and Efficacy of 25 and 50 mg Doses of Proellex® in Treating the Recurrence of Uterine Fibroid Symptoms

Uterine Fibroids

United States, Brazil
Endo Pharmaceuticals

Completed

Study to Evaluate Efficacy and Safety of Histrelin Subdermal Implant in Men With Advanced Prostate Cancer

Prostate Cancer | Adenocarcinoma of the Prostate
National Cancer Institute (NCI)

Completed

Positron Emission Tomography and Magnetic Resonance Imaging for Prostate Cancer

Prostate Cancer

United States
Repros Therapeutics Inc.

Completed

A Safety and Pharmacokinetic Study of Proellex® (PK)

Healthy

United States
Turku University Hospital

Completed

PET/MRI and Biomarkers in Bladder Cancer (ACEBIB)

Bladder Cancer

Finland
Baker Heart and Diabetes Institute

Completed

Effect of Ghrelin on Sympathetic Nervous System

Healthy | Obesity

Australia
Repros Therapeutics Inc.

Completed

Comparison of Two Formulations of Proellex for Oral Administration

Healthy

United States
Repros Therapeutics Inc.

Completed

Proellex® Pharmacokinetic Bridging Study II (PK)

Healthy

United States

Search clinical trials for: Lapaquistat acetate

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