Search clinical trials for: LentiGlobin BB305 Drug Product

Total 1846 results

bluebird bio

Completed

A Study Evaluating the Safety and Efficacy of LentiGlobin BB305 Drug Product in β-Thalassemia Major (Also Referred to as Transfusion-dependent β-Thalassemia [TDT]) and Sickle Cell Disease

Sickle Cell Disease | Beta-Thalassemia Major

France
bluebird bio

Completed

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia

Beta-Thalassemia

United States, Germany, United Kingdom, France, Greece, Italy
bluebird bio

Completed

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia, Who do Not Have a β0/β0 Genotype

Beta-Thalassemia

France, United Kingdom, United States, Thailand, Italy, Germany
bluebird bio

Completed

A Study Evaluating the Safety and Efficacy of the LentiGlobin BB305 Drug Product in β-Thalassemia Major Participants

β-thalassemia Major

United States, Australia, Thailand
bluebird bio

Recruiting

A Study Evaluating Gene Therapy With BB305 Lentiviral Vector in Sickle Cell Disease

Sickle Cell Disease

United States
bluebird bio

Completed

A Study Evaluating the Safety and Efficacy of bb1111 in Severe Sickle Cell Disease

Sickle Cell Disease

United States
Gruppo Italiano Trapianto di Midollo Osseo

Recruiting

Pentaglobin in CRE and PA Neutropenic Infections (PENTALLO)

Septic Shock

Italy
Northwestern University

Completed

Skin Care for Cancer Patients: A Product Satisfaction Survey

Skin Toxicity

United States
Centre hospitalier de l'Université de Montréal...

Completed

Efficacy of Intranasal Probiotic Treatment to Reduce Severity of Symptoms in COVID19 Infection

COVID-19 Infection

Canada
British American Tobacco (Investments) Limited

Completed

A Study to Characterize Nicotine Pharmacokinetics and Subjective Effects of Nicotine Pouches in Adult Cigarette Smokers

Tobacco Use | Tobacco Smoking

United States
RAI Services Company

Completed

CSD190301: A Study to Assess Elements of Abuse Liability for Two Dissolvable Nicotine Lozenge Tobacco Products

Smoking | Tobacco Use | Tobacco Smoking

United States
Università Politecnica delle Marche

Completed

Effects on Microcirculation of IgGAM in Severe Septic/Septic Shock Patients.

Septic Shock | Severe Sepsis

Italy
RAI Services Company

Completed

CSD200907: A Study to Assess Elements of Abuse Liability for a Heated Tobacco Product With Four Non-Combusted Cigarette Variants

Smoking | Tobacco Use | Tobacco Smoking | Smoking Behaviors

United States
RAI Services Company

Completed

CSD201002: Study to Assess Nicotine Uptake From P10 Nicotine Pouches

Smoking | Tobacco Use

United States
British American Tobacco (Investments) Limited

Completed

A Study to Assess the Pharmacokinetics of Oral Nicotine Pouches and Lozenges in Healthy Adults

Tobacco Use | Tobacco Smoking | Cigarette Smoking

United States
RAI Services Company

Completed

CSD210202: A Study to Assess Nicotine Uptake From Electronic Nicotine Delivery Systems

Smoking | Tobacco Use | Tobacco Smoking | Smoking Behaviors

United States
RAI Services Company

Completed

CSD190401: A Study to Assess Elements of Abuse Liability for Nicotine-containing Pouch Tobacco Products

Smoking | Tobacco Use | Tobacco Smoking | Smoking Behaviors

United States
RAI Services Company
Celerion

Completed

CSD170401: Study to Assess Elements of Abuse Liability for Three Electronic Tobacco Vapor Products During an 11-Day In-Clinic Confinement

Smoking

United States
RAI Services Company

Completed

CSD201301: Study to Assess Elements of Abuse Liability for Four P13 Nicotine Pouches

Smoking | Tobacco Use | Tobacco Smoking

United States
RAI Services Company

Completed

CSD201201: Study to Assess Elements of Abuse Liability for Electronic Nicotine Delivery System P12

Smoking | Tobacco Use | Tobacco Smoking | Smoking Behaviors

United States
RAI Services Company

Recruiting

CSD201001: Study to Assess Elements of Abuse Liability for Three Nicotine Pouches

Smoking | Tobacco Use | Tobacco Smoking

United States
Imperial Brands PLC

Active, not recruiting

A Relative Bioavailability Study of Nicotine Delivery From Selected Oral Nicotine Products

Healthy Volunteers

Sweden
RAI Services Company
ICON plc

Completed

CSD190202: Study to Assess Elements of Abuse Liability for Two Electronic Nicotine Delivery Systems

Smoking | Tobacco Use | Tobacco Smoking

United States
Imperial Brands PLC

Completed

A Randomised, Cross-over, Relative Bioavailability Study of Nicotine Delivery and Nicotine Extraction From Oral Products

Healthy Volunteers

Sweden
Danone Research

Completed

Metabolic Response to Beverages With Various Sweetening Systems Consumed During Meal in Overweight and Obese Subjects (AQUAGLU-1)

Overweight and Obesity

France
Novo Nordisk A/S

Completed

Injection Site Pain Comparison of Excipient Solutions

Obesity

Netherlands
Pharmtechnology LLC
Algorithme Pharma, An Altasciences Company

Completed

Bioequivalence Study of Two Formulations of Telmisartan 80 mg Tablets in Healthy Adult Volunteers Under Fasting State

Bioequivalence

Canada
Fakultas Kedokteran Universitas Indonesia

Unknown

IgM-Enriched Immunoglobulin for Neonatal Sepsis

Inflammation | Infant, Newborn, Disease | Very Low Birth Weight Infant | Neonatal Sepsis, Early-Onset
Lund University
Vinnova; Öste Venture AB

Completed

Dietary Fibre and Metabolic Benefits

Glucose Tolerance

Sweden
Sanofi

Completed

Study of the Tolerability of Different SAR153191 Drug Products, That Differ With Respect to Manufacturing Processes and Formulation, at Different Concentrations and Doses in Healthy Male Subjects

Rheumatoid Arthritis
Sir Takhtasinhji General Hospital

Completed

Efficacy of IgM Rich Immunoglobulin With Antibiotics for Bacterial Sepsis in Very Low Birth Weight Preterm Neonates (IgMNS)

Neonatal SEPSIS | Very Low Birth Weight Baby

India
Amplicon AB

Recruiting

Study to Assess PK, PD, Nicotine Extraction, Palatability, Subjective Effects of Nicotine Pouches - Daily Nicotine Users

Nicotine Use Disorder

Sweden
GlaxoSmithKline

Completed

An Open Label, Randomised, Repeat Dose Study to Assess the Pharmacokinetic Performance of Five Ezogabine/Retigabine Modified Release (MR) Formulations at Steady State Compared to the Immediate Release (IR) Formulation.

Epilepsy

United States
GlaxoSmithKline

Completed

Efficacy Study of Protein Supplementation in Attenuating the Decline in Performance After Strenuous Concurrent Exercise

Sports Nutritional Sciences

United Kingdom
Universidad Católica San Antonio de Murcia

Completed

Efficacy of Different Types of Milk in Improving Sleep Quality in Subjects With Sleep Problems (Milca) (Milca)

Poor Quality Sleep

Spain
Altria Client Services LLC

Completed

Study to Evaluate Changes in Smokers Using on!® Nicotine Pouches

Tobacco Use

United States
Henry Ford Health System
Allergan

Completed

The Effect of Topical Sunscreen Plus Antioxidant Against the Visible Light Biological Effects

Pigmentation

United States
Harokopio University
National and Kapodistrian University of Athens

Completed

Cereal-based Products Fortified With Legumes and Effects on Glycemic Control and Appetite Regulation

Appetite

Greece
Mondelēz International, Inc.
University of Sydney

Completed

Determination of the Glycaemic Index and Insulinaemic Index Values of Five Cereal Products

Metabolic Disorder

Australia
Pierre Fabre Medicament

Completed

Exploratory Study in the Relief of Drug-induced Xerostomia Associated With Hyposialia

Drug-induced Xerostomia

Germany
Shenzhen Precision Health Food Technology Co. Ltd...

Active, not recruiting

The Efficacy on Overweight With Oral Supplemenation of Probiotics and Prebiotics

Overweight

China
Roquette Canada, LTD.

Completed

Investigation of the Efficacy and Safety of Three Test Products and Comparator on Muscular Performance After the Initiation of a Resistance Training Program

Muscle Strength

Canada
AB Biotics, SA

Completed

Impact of a Probiotic-based Formula on Digestive Symptoms and Mood in Ultra Marathon Runners (AB-ULTRA)

Signs and Symptoms

Spain
King's College London

Recruiting

Micronutrient Bioavailability From Wheat

Healthy

United Kingdom
Biogen

Completed

Study in Healthy Volunteers to Establish the Bioequivalence of Two Different Manufacturers.

Healthy Volunteers

United States
Assistance Publique - Hôpitaux de Paris

Active, not recruiting

Safety and Efficacy of Gene Therapy of the Sickle Cell Disease by Transplantation of an Autologous CD34+ Enriched Cell Fraction That Contains CD34+ Cells Transduced ex Vivo With the GLOBE1 Lentiviral Vector Expressing the βAS3 Globin Gene in Patients With Sickle Cell Disease (DREPAGLOBE) (DREPAGLOBE)

Sickle Cell Disease

France
Assistance Publique - Hôpitaux de Paris

Recruiting

Safety and Efficacy Study of Transplantation of Autologous CD34+ Cells Transduced With the G2ARTE Lentiviral Vector Expressing the DCLRE1C cDNA in Artemis (DCLRE1C) Deficient Severe Combined Immunodeficiency Patients (ARTEGENE) (ARTEGENE)

Artemis (DCLRE1C ) Deficient Severe Combined Immunodeficiency

France
Colgate Palmolive

Completed

Clinical Study on Malodor

Oral Malodor

China
Société des Produits Nestlé (SPN)

Completed

Nutritional Intervention to Improve Sleep Quality and Improve Next-day Mood and Cognitive Benefits (Twinkle)

Sleep

Singapore
Danisco
BioFortis

Completed

Effect of an 8-week Bifidobacterium Lactis HN019 Supplementation on Functional Constipation (BifidoDigest)

Functional Constipation

France

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