Search clinical trials for: MEDI0382 mid dose

Total 10281 results

Innovent Biologics (Suzhou) Co. Ltd.

Completed

Single Dose Tolerability and Pharmacokinetics of IBI112 in Healthy Subjects

Healthy Subjects

China
AstraZeneca
MedImmune LLC

Completed

A Study to Evaluate the Efficacy and Safety of MEDI0382 in the Treatment of Overweight and Obese Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2

Germany, United States, Canada, Russian Federation, Slovakia, Czechia, Bulgaria, Mexico
MedImmune LLC

Completed

A Study to Evaluate Safety and Pharmacodynamic Efficacy of 0382 in Obese Subjects With NAFLD/NASH.

Non-alcoholic Fatty Liver Disease (NAFLD) | Non-alcoholic Steatohepatitis (NASH)

United States, Puerto Rico
Aclaris Therapeutics, Inc.

Completed

ATI-501 Oral Suspension Compared to Placebo in Subjects With Alopecia Areata, Alopecia Universalis or Alopecia Totalis

Alopecia

United States
Oblato, Inc.

Recruiting

Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients With Recurrent High-Grade Glioma

Astrocytoma | Glioblastoma Multiforme | Oligodendroglioma | High-grade Glioma

United States
Chiesi Farmaceutici S.p.A.

Completed

Phase II Study to Evaluate the Cardiac Safety of 2 Doses of CHF5993 Both Combined With CHF1535 BID Versus CHF1535 BID in Patients With Moderate to Severe COPD (CARSAF)

Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Bulgaria, Germany, Hungary, Poland, Russian Federation, United Kingdom
AstraZeneca

Completed

Safety and Tolerability Study of MEDI0382 in Japanese Preobese or Obese Subjects With Type 2 Diabetes

Type 2 Diabetes

Japan
Lexeo Therapeutics

Recruiting

Gene Therapy for Cardiomyopathy Associated With Friedreich's Ataxia

Friedreich Ataxia | Cardiomyopathy, Secondary

United States, Canada
University of Oxford

Completed

Research Study to Assess New Chikungunya and Zika Vaccines in Healthy Adults in Mexico.

Chikungunya | Zika

Mexico
MedImmune LLC

Completed

A Multiple-ascending-dose Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of MEDI0382 in Overweight and Obese Participants With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Germany
MedImmune LLC

Completed

A Phase 1, Single Dose Study to Evaluate the Safety and Pharmacokinetics of MEDI0382 in Healthy Volunteers

Healthy Volunteers

Germany
MedImmune LLC

Completed

A Study to Evaluate Pharmacokinetics, Safety and Tolerability of MEDI0382 in Renal Impairment Subjects

Renal Insufficiency

New Zealand, Germany
Samjin Pharmaceutical Co., Ltd.

Completed

Clinical Study to Investigate the Efficacy and Safety of Orally Administered SA001 in Patients With Dry Eye Syndrome.

Dry Eye Syndrome

Korea, Republic of
AsclepiX Therapeutics, Inc.

Recruiting

Safety and Bioactivity of AXT107 in Subjects With Neovascular Age-Related Macular Degeneration (nAMD) (DISCOVER)

Neovascular Age-related Macular Degeneration

United States
Emmecell

Recruiting

Study of Safety and Tolerability of EO2002 in the Treatment of Corneal Edema

Endothelial Dysfunction | Corneal Edema | Fuchs Dystrophy | Corneal Endothelial Dystrophy | Bullous Keratopathy | Pseudophakic Bullous Keratopathy | Corneal Endothelial Dysfunction | Fuchs Endothelial Corneal Dystrophy | Moderate Corneal Endothelial Decompensation

United States
Samjin Pharmaceutical Co., Ltd.

Completed

Clinical Study to Investigate the Efficacy of Orally Administered SA001 in Patients With Primary Sjögren's Syndrome

Primary Sjögren's Syndrome (pSS)

Korea, Republic of
University of Missouri-Columbia
National Center for Complementary and Integrative Health (NCCIH); Office of...

Completed

A Controlled Study of the Safety and Efficacy of Lessertia Frutescens in HIV-infected South African Adults

HIV Infections

South Africa
MedImmune LLC

Completed

A Study to Evaluate the Safety and Tolerability of MEDI0382 in Overweight and Obese Participants With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Germany
MedImmune LLC

Completed

A Study to Investigate Different Doses of 0382 in Overweight and Obese Subjects With Type 2 Diabetes Mellitus.

Type 2 Diabetes Mellitus

Germany
MedImmune LLC

Completed

A Pilot Study Investigating Bioequivalence Between a Single Dose of Formulation 2 and Formulation 3 of MEDI0382

Type 2 Diabetes Mellitus

United States
Oncocross Australia Pty Ltd.

Completed

A First in Human Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics Effects of OC514

Cancer Cachexia

Australia
MedImmune LLC

Completed

A Study to Evaluate the Effect of MEDI0382 on Energy Balance in Overweight and Obese Participants With Type 2 Diabetes Mellitus

Obesity | Diabetes Mellitus, Type II

United Kingdom
MedImmune LLC

Completed

A Study to Evaluate the Safety and Pharmacokinetics of MEDI0382 in Overweight/Obese Subjects of Japanese or Chinese Descent

Healthy Subjects | Safety

United States
Frontera Therapeutics

Recruiting

Gene Therapy in Subjects With Biallelic RPE65 Mutation-associated Retinal Dystrophy

Biallelic RPE65 Mutation-associated Retinal Dystrophy

China
Kangpu Biopharmaceuticals, Ltd.

Active, not recruiting

Phase 1b/2a Study to Evaluate Safety and Efficacy of KPG-818 in SLE (Lupus)

SLE; Drug

United States
MedImmune LLC

Completed

A Study to Assess Safety, Tolerability, and Pharmacokinetics of MEDI0382 in Non-diabetic Obese Participants

Obesity

United States
Anavex Life Sciences Corp.
Anavex Australia Pty Ltd.; Anavex Germany GmbH; Anavex Canada Ltd.

Completed

ANAVEX2-73 for Treatment of Early Alzheimer's Disease

Alzheimer Disease

Australia, Canada, Germany, Netherlands, United Kingdom
Anavex Life Sciences Corp.
Anavex Germany GmbH

Completed

ANAVEX2-73 Study in Parkinson's Disease Dementia

Parkinsons Disease With Dementia

Spain, Australia
Genocea Biosciences, Inc.

Completed

Safety and Immunogenicity Study of Prophylactic Streptococcus Pneumoniae Vaccine

Streptococcus Pneumoniae

United States
Kolon TissueGene, Inc.

Not yet recruiting

Study to Determine the Safety and Tolerability of TG-C in Subjects With Back Pain Due to Degenerative Disc Disease

Degenerative Disc Disease
Pfizer

Completed

A Study To Examine The Safety, Pharmacokinetics And Pharmacodynamics Of PF-03635659 In Patients With Chronic Obstructive Pulmonary Disease

Respiratory Tract Diseases | Lung Diseases | Pulmonary Disease, Chronic Obstructive | COPD | Chronic Obstructive Airway Disease

Germany
The University of Texas Health Science Center,...

Terminated

Dose Ranging Study of the Safety and Efficacy of Orally Administered Lyophilized Fecal Microbiota Product (PRIM-DJ2727) for the Treatment of Recurrent Clostridium Difficile Infection (CDI)

Recurrent C. Difficile Infection

United States
Taiho Pharmaceutical Co., Ltd.

Recruiting

A Study of TAS3731 in Healthy Adults

Healthy Adult Males

Japan
Azura Ophthalmics
Syneos Health; Cliantha Research

Completed

A Multicenter Study Evaluating AZR-MD-001 in Patients With Meibomian Gland Dysfunction and Evaporative Dry Eye Disease (DED)

Dry Eye | Meibomian Gland Dysfunction

Canada, Australia, New Zealand
Ocugen

Recruiting

Study to Assess the Safety and Efficacy of OCU400 for Retinitis Pigmentosa and Leber Congenital Amaurosis (OCU400)

Retinitis Pigmentosa | Leber Congenital Amaurosis

United States
Reistone Biopharma Company Limited

Terminated

Assess the Efficacy and Safety of SHR0302 Ointment in Adult Patients With Vitiligo

Vitiligo

China
Johns Hopkins University

Withdrawn

Feasibility and Efficacy of Dietary Interventions for Older Adults With Subjective Cognitive Decline

Cognitive Impairment | Alzheimer Disease
Institute of Medical Biology, Chinese Academy of...
Guangxi Center for Disease Control and Prevention

Completed

Clinic Trial to Evaluate the Safety and Immunogenicity by Different Sequential Schedules of bOPV and IPV

Poliomyelitis

China
Duke University
National Institutes of Health (NIH)

Not yet recruiting

Mechanistic Study of Inspiratory Training in Childhood Asthma (MICA) (MICA)

Obesity | Pediatric Obesity | Asthma in Children | Pediatric Asthma

United States
Medigen Vaccine Biologics Corp.

Completed

A Study to Evaluate MVC-COV1901 Vaccine Against COVID-19 in Elderly Adults

Covid19 Vaccine

Taiwan
Pearl Therapeutics, Inc.

Completed

Efficacy and Safety Study of Two Dose Levels of AZD2115 in Subjects With Moderate to Severe COPD

Chronic Obstructive Pulmonary Disease (COPD)

United States
Chiesi Farmaceutici S.p.A.

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Inhaled CHF6001 (CHF6001Ext)

Chronic Obstructive Pulmonary Disease

United Kingdom
Allena Pharmaceuticals

Completed

Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Hyperoxaluria and Kidney Stones

Nephrolithiasis | Kidney Stones | Hyperoxaluria | Secondary Hyperoxaluria | Dietary Hyperoxaluria

United States
Lexicon Pharmaceuticals

Completed

Study of LX3305 in Subjects With Active Rheumatoid Arthritis on Stable Methotrexate

Rheumatoid Arthritis

United States, Bulgaria, Czech Republic, Hungary, Poland, Serbia
Cellular Biomedicine Group Ltd.
RenJi Hospital

Completed

Autologous Adipose Tissue Derived Mesenchymal Stem Cells Therapy for Patients With Knee Osteoarthritis

Knee Osteoarthritis

China
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Safety and Efficacy Study of SHR4640 and Febuxostat in Subjects With Hyperuricemia

Hyperuricemia
Oryn Therapeutics, LLC

Withdrawn

A Study of ORTD-1 in Patients Hospitalized With COVID-19 Related Pneumonia

COVID-19

United States
Alkermes, Inc.

Completed

A Study of ALKS 9072 in Subjects With Chronic Stable Schizophrenia

Schizophrenia

United States
Janssen Research & Development, LLC

Completed

A Study of Seltorexant (JNJ-42847922) After Single-Dose Administration in Healthy Participants

Healthy

United States
Sun Yat-sen University

Unknown

Mild-dose IMRT for Early-staged Extranodal Nasal-type NK/T-cell Lymphoma With CR Tumor After GELOX Chemotherapy

Lymphoma, | Non-Hodgkin Lymphoma, | Extranodal NK/T-cell Lymphoma,Nasal-type,

China

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