Search clinical trials for: MEK or PI3K Inhibitor
Total 2606 results
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University Health Network, TorontoActive, not recruitingSalivary Gland Cancer | Metastatic | Recurrent | AdvancedCanada
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Institute of Hematology & Blood Diseases Hospital...YL-PharmaRecruitingRelapsed/Refractory Large Granular T Lymphocytic LeukemiaChina
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SecuraBioTerminatedLymphoma | Lymphoma, Non-Hodgkin | Follicular Lymphoma | Chronic Lymphocytic Leukemia | Lymphoma, Small LymphocyticUnited States
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PIQUR Therapeutics AGCharite University, Berlin, Germany; University Hospital, Basel, Switzerland; University Hospital Freiburg and other collaboratorsCompletedLymphoma | Non-Hodgkin LymphomaGermany
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PIQUR Therapeutics AGM.D. Anderson Cancer Center; Mayo Clinic; University College London Hospitals; Hospital... and other collaboratorsCompleted
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PIQUR Therapeutics AGRoyal Marsden NHS Foundation Trust; University College London Hospitals; Weill... and other collaboratorsCompletedLymphoma, MalignantUnited States, United Kingdom, Serbia, Bosnia and Herzegovina, France, Israel
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Kazia Therapeutics LimitedQuotient SciencesCompleted
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SecuraBioCompletedAsthmaGermany, United Kingdom
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Mayo ClinicNational Cancer Institute (NCI)CompletedRecurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Refractory Mantle Cell Lymphoma | Transformed Recurrent Non-Hodgkin LymphomaUnited States
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Anne ChangNovartis PharmaceuticalsTerminatedCarcinoma, Basal Cell | Skin Neoplasms | Basal Cell Nevus Syndrome | Recurrent Skin CancerUnited States
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Rhizen Pharmaceuticals SACompletedLymphoma, T-Cell, Cutaneous | Lymphoma, T-Cell, PeripheralUnited States
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NRG OncologyNational Cancer Institute (NCI)CompletedEndometrial Endometrioid Adenocarcinoma | Endometrial Mixed Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Undifferentiated Carcinoma | Recurrent Uterine Corpus Cancer | Metastatic Endometrioid AdenocarcinomaUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingProgressive Disease | Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Endometrial Carcinoma | Endometrial Adenocarcinoma | Primary Peritoneal High Grade Serous Adenocarcinoma | Platinum-Resistant Ovarian Carcinoma | High Grade Ovarian... and other conditionsUnited States
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Rhizen Pharmaceuticals SACompletedLymphoma, B-Cell | T-Cell LymphomaFrance, Italy
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National Cancer Institute (NCI)Active, not recruitingHematopoietic and Lymphoid Cell Neoplasm | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple MyelomaUnited States
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Alliance for Clinical Trials in OncologyNational Cancer Institute (NCI); Eli Lilly and Company; Genentech, Inc.; Kazia... and other collaboratorsRecruitingMetastatic Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Brain | NTRK Family Gene Mutation | CDK Gene Mutation | PI3K Gene Mutation | ROS1 Gene Mutation | KRAS G12C MutationUnited States
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National Cancer Institute (NCI)Active, not recruitingHematopoietic and Lymphoid Cell Neoplasm | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple MyelomaUnited States
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SecuraBioCompletedA Phase 3 Study of Duvelisib Versus Ofatumumab in Patients With Relapsed or Refractory CLL/SLL (DUO)Chronic Lymphocytic Leukemia | Small Lymphocytic LymphomaBelgium, France, Italy, Spain, United States, Austria, New Zealand, Hungary, Germany, United Kingdom, Australia
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SecuraBioCompletedChronic Lymphocytic Leukemia | Small Lymphocytic LymphomaBelgium, France, Italy, Spain, United States, Austria, New Zealand, Hungary, United Kingdom, Australia, Germany
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Rhizen Pharmaceuticals SACompleted
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Medikine, Inc.Medikine Australia Pty Ltd.CompletedHealthy VolunteersAustralia
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Columbia UniversityRecruitingCancer | Insulin Resistance | MTOR Gene Mutation | PI3K Gene Mutation | AKT Gene MutationUnited States
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Henan Cancer HospitalRecruitingPeripheral T-Cell LymphomaChina
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M.D. Anderson Cancer CenterWithdrawnLocally Advanced Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Bone
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University of NebraskaNational Cancer Institute (NCI)CompletedRecurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell LymphomaUnited States
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SpringWorks Therapeutics, Inc.AvailableNeurofibromatosis Type 1-Associated Plexiform Neurofibromas | Histiocytic Neoplasm | Other MAP-K Pathway Driven Diseases
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Genentech, Inc.Completed
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Jiangsu HengRui Medicine Co., Ltd.Unknown
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CStone PharmaceuticalsCompletedSolid Tumor, AdultAustralia
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Karus Therapeutics LimitedCompletedLymphoma, B CellUnited States
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Hospices Civils de LyonUniversity of KonstanzCompleted
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UNC Lineberger Comprehensive Cancer CenterGlaxoSmithKlineCompletedUnresectable Melanoma | Stage IV Melanoma | Stage III Melanoma | BRAF Mutant MelanomaUnited States
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EMD SeronoSanofiCompletedMelanoma | Breast Cancer | Colorectal Cancer | Non Small Cell Lung Cancer | Metastatic Solid Tumor | Locally Advanced Solid TumorUnited States, Italy, Spain
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M.D. Anderson Cancer CenterTerminated
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Array Biopharma, now a wholly owned subsidiary...Completed
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Henan Cancer HospitalRecruitingDigestive System TumorsChina
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Array Biopharma, now a wholly owned subsidiary...Completed
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National Cancer Institute (NCI)Completed
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Array Biopharma, now a wholly owned subsidiary...CompletedRheumatoid ArthritisBrazil, Argentina, United States, Poland, Hungary, Peru, Romania
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Cliniques universitaires Saint-Luc- Université...NovartisTerminatedCarcinoma Transitional CellBelgium, Luxembourg
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Memorial Sloan Kettering Cancer CenterAstraZeneca; Novartis PharmaceuticalsRecruitingBreast CancerUnited States
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University Hospital, CaenActive, not recruiting
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MyoKardia, Inc.CompletedDilated CardiomyopathyAustralia
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GlaxoSmithKlineCompletedVomiting | Cardiovascular Event | Arterial Thromboembolic Event
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Atriva Therapeutics GmbHSGS Life Sciences, a division of SGS Belgium NVCompleted
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National Cancer Institute (NCI)Active, not recruitingMalignant Solid NeoplasmUnited States
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Hunan Cancer HospitalCompletedMetastatic Breast Cancer | Circulating Tumor DNA | Gene Abnormality
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University of California, San FranciscoNational Institute of Neurological Disorders and Stroke (NINDS); The Chad-Tough... and other collaboratorsRecruitingDiffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | Recurrent Diffuse Intrinsic Pontine Glioma | Recurrent Diffuse Midline Glioma, H3 K27M-Mutant | Recurrent WHO Grade III Glioma | WHO Grade III GliomaUnited States, Israel, Australia, Netherlands, Switzerland, New Zealand
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University of California, DavisNational Cancer Institute (NCI); Merck Sharp & Dohme LLC; NovartisActive, not recruitingKRAS Gene Mutation | Stage IV Non-Small Cell Lung Cancer AJCC v7 | Recurrent Non-Squamous Non-Small Cell Lung Carcinoma | Metastatic Non-Squamous Non-Small Cell Lung CarcinomaUnited States
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National Cancer Institute (NCI)CompletedStage IV Skin Melanoma | Recurrent Melanoma | Stage III Skin MelanomaUnited States