Search clinical trials for: Manganese Chloride

Total 3099 results

Chinese PLA General Hospital

Recruiting

An Open-label, Phase I/II Study of Manganese Plus Radiotherapy in Patients With Metastatic Solid Tumors or Lymphoma

Lymphoma | Solid Tumor

China
Hospital Sirio-Libanes

Completed

Exploratory Study to Determine Tissue Alterations of Advanced Hepatocellular Carcinoma Induced by Electromagnetic Waves of Low Energy Amplitude Modulated to Specific Frequencies During Imaging Study by MRI

Primary or Metastatic Tumor in the Liver Parenchyma

Brazil
Sharp HealthCare
Food and Drug Administration (FDA)

Completed

Safety of Manganese Restriction in Neonatal Parenteral Nutrition

Infant, Newborn, Disease

United States
Chinese PLA General Hospital

Unknown

A Safety Study of the Pan-immunotherapy in Patients With Unresectable/Metastatic Solid Tumors or Lymphomas

Lymphoma | Solid Tumor

China
Galera Therapeutics, Inc.

Terminated

Effects of Intravenous GC4419 on the Incidence and Severity of Esophagitis Due to Chemoradiotherapy for Lung Cancer

Esophagitis

United States
Stanford University

Completed

Efficacy of EVP 1001-1 (SeeMore) in the Assessment of Myocardial Viability in Patients With Cardiovascular Disease

ISCHEMIC CARDIOMYOPATHY

United States
Galera Therapeutics, Inc.

Terminated

Phase I/II Study of SBRT and GC4711 for Centrally Located or Large NSCLC (GRECO-1)

NSCLC | SBRT | Non-metastatic

United States
Galera Therapeutics, Inc.

Completed

ROMAN: Phase 3 Trial Investigating the Effects of GC4419 on Radiation Induced Oral Mucositis in Head/Neck Cancer Patients

Oral Mucositis

United States, Puerto Rico, Canada
University of Nebraska
BioMimetix JV, LLC

Recruiting

Safety Study of BMX-001 (Radio-protector) in Patients With Newly Diagnosed Anal Cancer

Radiation Exposure | Anal Cancer, Squamous Cell Carcinoma

United States
Stanford University
General Electric

Completed

Clinical Trial of Manganese-Enhanced MRI (MEMRI) to Assess Peri-Infarct Injury

ISCHEMIC CARDIOMYOPATHY

United States
Chinese PLA General Hospital

Completed

An Open-label, Phase I/II Study of the Pan-immunotherapy in Patients With Relapsed/Refractory Ovarian Cancer

Ovarian Cancer

China
BioMimetix JV, LLC
Duke University; University of California, San Francisco

Withdrawn

Trial of BMX-001 or Placebo in Head and Neck Cancer Patients

Head and Neck Cancer
Galera Therapeutics, Inc.
M.D. Anderson Cancer Center

Completed

Pilot Dose Escalation Trial of Stereotactic Body Radiation Therapy (SBRT) in Combination With GC4419 in Pancreatic Cancer

Pancreatic Cancer | Stereotactic Body Radiation Therapy

United States
M.D. Anderson Cancer Center
Bayer; Prostate Cancer Foundation

Completed

Radium 223 in Castrate Resistant Prostate Cancer Bone Metastases

Prostate Cancer

United States
North-West University, South Africa
Global Alliance for Improved Nutrition; Unilever R&D; DSM Ltd

Completed

Randomized Controlled Trial in South Africa Comparing the Efficacy of Complementary Food Products on Child Growth (TSWAKA)

Malnutrition

South Africa
BioMimetix JV, LLC
National Cancer Institute (NCI); Duke Cancer Institute

Active, not recruiting

Trial of Newly Diagnosed High Grade Glioma Treated With Concurrent Radiation Therapy, Temozolomide and BMX-001 (BMX-HGG)

Glioblastoma | High Grade Glioma | Astrocytoma, Grade III

United States
Chinese PLA General Hospital

Unknown

A Phase I/II Study of the Pan-immunotherapy in Patients With Local Advanced/Metastatic BTC

Biliary Tract Cancer (BTC)

China
Bayer

Completed

Alpharadin™ (Radium-223 Chloride) Safety and Dosimetry With HRPC That Has Metastasized to the Skeleton

Prostate Cancer | Pharmacokinetics | Metastases

United States
Chinese PLA General Hospital

Unknown

An Open-label, Phase I/II Study of the Pan-immunotherapy in Patients With Local Advanced/Metastatic Pancreatic Cancer

Pancreatic Cancer

China
Galera Therapeutics, Inc.

Completed

Study to Evaluate the Effects of Renal Impairment on the Pharmacokinetics, Safety and Tolerability of GC4419

Renal Impairment

United States
University of Southern California
National Cancer Institute (NCI)

Active, not recruiting

Enzalutamide With or Without Radium Ra 223 Dichloride in Patients With Metastatic, Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IV Prostate Cancer | Prostate Carcinoma Metastatic in the Bone

United States
AGUNCO Obstetrics and Gynecology Centre

Completed

Myo-inositol Versus D-chiro-inositol in the Treatment of Polycystic Ovary Syndrome and Insulin Resistance: Evaluation of Clinical, Metabolic, Endocrine and Ultrasound Parameters

PCOS

Italy
Bayer

Completed

BAY88-8223, Alpharadin, Breast Cancer Patients With Bone Dominant Disease

Breast Cancer | Bone Metastases

Belgium, United Kingdom, Norway
Galera Therapeutics, Inc.
Celerion

Completed

A Study to Investigate the Absorption, Metabolism, Excretion, and Mass Balance of GC4419 in Healthy Adult Subjects

Healthy | Healthy Volunteers

United States
McMaster University
Hamilton Health Sciences Corporation

Completed

Fluids in Sepsis and Septic Shock (FISSH)

Sepsis | Septic Shock

Canada
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust

Completed

Nebulised Hypertonic Saline in Children and Young People With Neuromuscular Disease and Cerebral Palsy

Neuromuscular Diseases

United Kingdom
University of Jena

Completed

Sino-nasal Inhalation of Sodium Chloride 6,0% in Patients With Cystic Fibrosis and Chronic Rhinosinusitis

Cystic Fibrosis | Rhinosinusitis

Germany
Aga Khan University

Unknown

Comparison of Enteral Versus Intravenous Potassium Supplementation (EIPS)

Acute Hypokalemia

Pakistan
Joel Greenberger

Terminated

MnSOD (Esophageal Protectant) to Prevent Esophagitis During Radiation/Chemotherapy Treatment for Non-Small Cell Lung Cancer (NSCLC) (MnSOD)

Toxicity | Esophageal

United States
Galera Therapeutics, Inc.

Terminated

A Trial of GC4419 in Patients With Critical Illness Due to COVID-19

Covid19 | SARS-CoV-2 Infection

United States
National Cancer Institute (NCI)

Completed

Berberine Chloride in Preventing Colorectal Cancer in Patients With Ulcerative Colitis in Remission

Ulcerative Colitis

United States, China
Federal University of São Paulo

Completed

Fluid Therapy During Brain Tumor Resection in Children

Brain Neoplasms

Brazil
Bayer

Completed

PK in Pts With HRPC & Skeletal Metastes

Prostatic Neoplasms

United Kingdom
National Cancer Institute (NCI)

Recruiting

Testing the Addition of a New Anti-cancer Drug, Radium-223 Dichloride, to the Usual Treatment (Cabozantinib) for Advanced Renal Cell Cancer That Has Spread to the Bone, the RadiCaL Study

Clear Cell Renal Cell Carcinoma | Stage IV Renal Cell Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Bone | Chromophobe Renal Cell Carcinoma | Papillary Renal Cell Carcinoma | Collecting Duct Carcinoma | Kidney Medullary Carcinoma | Advanced Renal Cell Carcinoma | Unclassified Renal Cell Carcinoma

United States
Bayside Health
Australian and New Zealand College of Anaesthetists

Completed

Limiting IV Chloride to Reduce AKI After Cardiac Surgery (LICRA)

Patients Undergoing Cardiothoracic Surgery

Australia
Frank Mose
Herning Hospital

Completed

The Effect of Orally Administrated Nitrate on Renal Parameters and Systemic Haemodynamics (APNI)

Hypertension

Denmark
Sidney Kimmel Cancer Center at Thomas Jefferson...
Bayer; Janssen, LP; Prostate Cancer Clinical Trials Consortium

Completed

Phase IB Trial of Radium-223 and Niraparib in Patients With Castrate Resistant Prostate Cancer (NiraRad)

Stage IV Prostate Adenocarcinoma | Hormone-refractory Prostate Cancer | Prostate Carcinoma Metastatic to the Bone

United States
Göteborg University

Terminated

Saline Injections for Prophylactic Treatment of Chronic Migraine

Chronic Migraine

Sweden
Ain Shams University

Recruiting

Incidence of Acute Kidney Injury and Mortality in Critically Ill Patients: Urinary Chloride as a Prognostic Marker

Acute Kidney Injury

Egypt
Ziekenhuis Oost-Limburg

Completed

Liberal Use of Sodium in Ambulatory Heart Failure (LUSA-HF)

Heart Failure

Belgium
National Institute of Diabetes and Digestive and...

Terminated

Pre-ESRD Syndrome in High Risk African Americans

Blood Pressure

United States
M.D. Anderson Cancer Center
Bayer

Completed

Trial of Ra-223 Dichloride in Combination With Hormonal Therapy and Denosumab in the Treatment of Patients With Hormone-Positive Bone-Dominant Metastatic Breast Cancer

Breast Cancer

United States
University Hospital, Linkoeping

Unknown

Colloid Osmotic Pressure and Osmolality in Hyponatremia

Hyponatremia

Sweden
University Medical Center Groningen

Completed

Comparison of Two Potassium Targets Within the Normal Range in Intensive Care Patients (GRIP-COMPASS)

Cardiac Surgery | Critically Ill | Thoracic Surgery

Netherlands
Institut d'Anesthesiologie des Alpes Maritimes
Université de Nice Sophia Antipolis; Medical University of Grenoble

Completed

Preventive Sodium Lactate and Traumatic Brain Injury

Head Trauma

France
Amsterdam UMC, location VUmc

Active, not recruiting

Rhenium-188-HEDP vs. Radium-223-chloride in Patients With Advanced Prostate Cancer Refractory to Hormonal Therapy (RaRe)

Prostate Cancer Metastatic to Bone

Netherlands
Haudongchun Co., Ltd.

Unknown

Clinical Study to Evaluate the Efficacy of HUDC_VT in Patients With Bacterial Vaginosis

Bacterial Vaginosis | HUDC_VT | Haudongchun

Korea, Republic of
Galera Therapeutics, Inc.
Syneos Health

Completed

A Study Designed to Compare the Safety and Pharmacokinetics of Intravenously Administered Superoxide Dismutase Mimetic GC4711 and GC4419 in Healthy Volunteers

Healthy | Healthy Volunteers

Australia
Imam Abdulrahman Bin Faisal University

Unknown

Type and Frequency of Nasal Irrigation in Rhinosinusitis Patients

Otorhinolaryngologic Diseases | Rhinosinusitis

Saudi Arabia
University of Leicester

Recruiting

Prevalence and Determinants of Subclinical Cardiovascular Dysfunction in Adults With Type 2 Diabetes Mellitus (PREDICT)

Diabetes Mellitus, Type 2 | Diabetic Cardiomyopathies

United Kingdom

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