Search clinical trials for: Methotrexate

Total 1481 results

European Organisation for Research and Treatment...

Terminated

Transurethral Resection and Combination Chemotherapy in Treating Patients With Stage II or Stage III Bladder Cancer

Bladder Cancer

Italy
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Myelodysplastic Syndrome

Myelodysplastic Syndromes | Leukemia

United States
Pfizer

Completed

Observational Trial With Enbrel

Rheumatoid Arthritis

Germany
Chung Shan Medical University

Unknown

Etanercept Versus Adalimumab in the Treatment of Patients With Ankylosing Spondylitis. A Switch Study

Ankylosing Spondylitis

Taiwan
National Institute of Diabetes and Digestive and...

Completed

Experimental Studies of the Effects of Caffeine on Glucose Regulation

Diabetes Mellitus, Type 2
University of Washington
Merck Sharp & Dohme LLC

Recruiting

Pembrolizumab and Combination Chemotherapy Before Surgery for the Treatment of Muscle-Invasive Bladder Cancer

Stage IIIA Bladder Cancer AJCC v8 | Muscle Invasive Bladder Carcinoma | Stage II Bladder Cancer AJCC v8

United States
The First Affiliated Hospital of Soochow University
The First Affiliated Hospital with Nanjing Medical University; Shenzhen People... and other collaborators

Recruiting

Sitagliptin for Prevention of aGVHD After Alternative Donor Transplantation

Allogeneic Hematopoietic Stem Cell Transplantation | Acute-graft-versus-host Disease

China
Institute of Hematology & Blood Diseases Hospital
The First Affiliated Hospital of Nanchang University; Henan Cancer Hospital; The... and other collaborators

Recruiting

TPM Regimen (Thalidomide, Prednisone and Methotrexate) in LGLL

T-LGL Leukemia | Clpd-Nk

China
UNICANCER
Novartis; National Cancer Institute, France; Chugai Pharmaceutical; Ligue contre... and other collaborators

Active, not recruiting

Combined Chemotherapy With or Without Zoledronic Acid for Patients With Osteosarcoma (OS2006)

Sarcoma

France
JHSPH Center for Clinical Trials

Active, not recruiting

Adalimumab vs. Conventional Immunosuppression for Uveitis Trial (ADVISE)

Uveitis

United States, United Kingdom, Australia, Canada
University of New Mexico

Withdrawn

H-9926-LCH III: Treatment Protocol of the Third International Study for Langerhans Cell Histiocytosis

Leukemia

United States
Jonsson Comprehensive Cancer Center

Withdrawn

Donor Lymphocytes to Prevent Graft-Versus-Host Disease in Patients With Chronic Myeloid Leukemia

Leukemia | Graft Versus Host Disease
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Combination Chemotherapy, Monoclonal Antibody, and Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma

Lymphoma | Brain and Central Nervous System Tumors

United States
University of Southern California
CTI BioPharma

Withdrawn

Neoadjuvant Doxorubicin, Polyglutamate Paclitaxel, Capecitabine and Metronomic Chemotherapy in Breast Cancer

Breast Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Mantle Cell Lymphoma

Lymphoma | Graft Versus Host Disease

United States
Mesoblast International Sàrl
National Cancer Institute (NCI)

Withdrawn

OTI-010 for Graft-Versus-Host Disease Prophylaxis in Treating Patients Who Are Undergoing Donor Peripheral Stem Cell Transplantation for Hematologic Malignancies

Myelodysplastic Syndromes | Leukemia | Graft Versus Host Disease

United States
US Department of Veterans Affairs
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Completed

Rheumatoid Arthritis: Comparison of Active Therapies in Patients With Active Disease Despite Methotrexate Therapy (RACAT)

Rheumatoid Arthritis

United States, Canada
Children's Cancer and Leukaemia Group

Active, not recruiting

Observing Young Patients With Ependymoma Undergoing Standard Combination Chemotherapy

Brain and Central Nervous System Tumors | Ototoxicity | Cognitive/Functional Effects | Long-term Effects Secondary to Cancer Therapy in Children

United Kingdom
Grupo Oncologico Cooperativo del Sur

Suspended

Combination Chemotherapy in Treating Women With Stage III Breast Cancer

Breast Cancer

Argentina
National Cancer Institute (NCI)

Completed

Alemtuzumab With or Without Methotrexate and Mercaptopurine in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia

Recurrent Childhood Acute Lymphoblastic Leukemia

United States
Genentech, Inc.

Completed

A Study of the Safety and Efficacy of Rituximab in Patients With Moderate to Severe Rheumatoid Arthritis Receiving Methotrexate (RUMBA)

Rheumatoid Arthritis
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine and Busulfan Followed by Donor Peripheral Stem Cell Transplant and Antithymocyte Globulin, Tacrolimus, and Methotrexate in Treating Patients With Myeloid Cancer

Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy and Antithymocyte Globulin in Reducing Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplantation For Myelodysplastic Syndrome or Myeloproliferative Disorder

Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease

United States
Merck Sharp & Dohme LLC
Eisai Inc.

Active, not recruiting

Safety and Efficacy of Lenvatinib (E7080/MK-7902) in Combination With Pembrolizumab (MK-3475) Versus Lenvatinib as First-line Therapy in Participants With Advanced Hepatocellular Carcinoma (MK-7902-002/E7080-G000-311/LEAP-002)

Carcinoma, Hepatocellular

United States, Australia, Canada, Chile, China, Colombia, France, Germany, Ireland, Italy, Japan, Korea, Republic of, Mexico, New Zealand, Poland, Russian Federation, Spain, Taiwan, Thailand, Turkey, United Kingdom
PepsiCo Global R&D

Completed

Pilot Study Characterizing the Pharmacokinetic Profile of a Novel Encapsulated Caffeine Beverage in the Fed and Fasted States

Pharmacokinetics

United States
AryoGen Pharmed Co.

Completed

Assessment of Treatment Safety and Quality of Life in Patients Receiving Etanercept Biosimilar for Autoimmune Arthritis (ASQA)

Rheumatoid Arthritis | Psoriatic Arthritis | Ankylosing Spondylitis

Iran, Islamic Republic of
Pfizer

Completed

Etanercept (Enbrel) Special Investigation (Regulatory Post Marketing Commitment Plan)

Arthritis | Rheumatoid

Japan
Ain Shams University

Completed

Caffeine Intake Inrelation to Perioperative Analgesic Consumption

Analgesia | Caffeine

Egypt
Ferring Pharmaceuticals

Terminated

CNI-1493 for Treatment of Moderate to Severe Crohn's Disease (CD02)

Crohn Disease

United States
The Cleveland Clinic

Completed

Echinacea, Propolis and Vitamin C for URI Prevention in Preschoolers

Gastroenteritis | Common Cold

United States
St. Jude Children's Research Hospital
Syndax Pharmaceuticals

Not yet recruiting

Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Refractory Acute Myeloid Leukemia | Acute Leukemia of Ambiguous Lineage | Relapsed Acute Myeloid Leukemia

United States
Memorial Sloan Kettering Cancer Center
Amgen

Active, not recruiting

Blinatumomab and Tyrosine Kinase Inhibitor Therapy in People With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | Philadelphia Chromosome-Positive

United States
Italian Sarcoma Group

Active, not recruiting

ABCB1/P-glycoprotein Expression as Biologic Stratification Factor for Patients With Non Metastatic Osteosarcoma (ISG/OS-2)

Osteosarcoma

Italy
St. Jude Children's Research Hospital
Gateway for Cancer Research

Completed

Study of Venetoclax in Combination With Chemotherapy in Pediatric Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Leukemia of Ambiguous Lineage

Acute Myeloid Leukemia

United States
Xinhua Hospital, Shanghai Jiao Tong University...

Completed

MEDA Chemotherapy and Autologous Hematopoietic Stem Cell Transplantation for Stage IV Natural Killer/T-cell Lymphoma

Extranodal NK-T-Cell Lymphoma, Nasal Type

China
Nanfang Hospital of Southern Medical University

Completed

Sequential Application of Yisaipu® and DMARDs in Treating Mild-to-Moderate AS

Ankylosing Spondylitis

China
Sanofi
Regeneron Pharmaceuticals

Completed

To Evaluate The Effect Of SAR153191 (REGN88) Added To Other RA Drugs In Patients With RA Who Are Not Responding To Or Intolerant Of Anti-TNF Therapy (SARIL-RA-TARGET)

Rheumatoid Arthritis

Hungary, Portugal, Austria, United States, Argentina, Australia, Brazil, Canada, Czechia, Germany, Greece, Guatemala, Israel, Italy, Korea, Republic of, Lithuania, Mexico, New Zealand, Peru, Poland, Romania, Russian Federation, Spain, Taiwa... and more
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Acute Myeloid Leukemia in Second Remission

Leukemia

United States
Tongji Hospital

Unknown

Low-dose Chemotherapy Combine With Tyrosine Kinase Inhibitor to Treat ph+ Acute Lymphoblastic Leukemia Patients (TCLDCWTTNDPP)

ph+ Acute Lymphoblastic Leukemia

China
German Breast Group

Completed

Adjuvant Chemotherapy for Elderly Non Frail Patients With an Increased Risk for Relapse of a Primary Carcinoma of the Breast (ICE-II)

Breast Cancer

Germany
University of Alabama at Birmingham
Pfizer; Amgen; Barr Laboratories

Completed

Treatment of Early Aggressive Rheumatoid Arthritis (TEAR) (TEAR)

Rheumatoid Arthritis

United States
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy and Rituximab in Treating Young Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia

Recurrent Childhood Acute Lymphoblastic Leukemia | B-cell Childhood Acute Lymphoblastic Leukemia | Childhood Diffuse Large Cell Lymphoma | Childhood Immunoblastic Large Cell Lymphoma | Recurrent Childhood Large Cell Lymphoma | Recurrent Childhood Lymphoblastic Lymphoma | Recurrent Childhood Small... and other conditions

United States
Children's Hospital Los Angeles
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Followed by Radiation Therapy in Treating Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma

Brain and Central Nervous System Tumors

United States, Canada
University of Alabama at Birmingham
National Cancer Institute (NCI)

Completed

Liposomal Doxorubicin Plus Combination Chemotherapy in Treating Patients With AIDS-Associated Non-Hodgkin's Lymphoma

Lymphoma

United States
Tehran University of Medical Sciences

Unknown

Hematopoietic Stem Cell Transplantation for Malignant Infantile Osteopetrosis

Osteopetrosis

Iran, Islamic Republic of
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

G-CSF-Treated Donor Bone Marrow Transplant in Treating Patients With Hematologic Disorders

Sarcoma | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Methotrexate and Glucocorticoids in Treating Patients With Newly Diagnosed Acute Graft-Versus-Host Disease After Donor Stem Cell Transplant

Cancer

United States
Karolinska Institutet

Completed

Comparison of MTX+Anti-TNF to MTX+Conventional DMARDs in Patients With Early Rheumatoid Arthritis (RA) Who Failed MTX Alone (SWEFOT) (SWEFOT)

Rheumatoid Arthritis
St. Jude Children's Research Hospital

Completed

Treatment of Burkitt Lymphoma/Leukemia and B Large Cell NHL

Non-Hodgkin Lymphoma | Acute Lymphoblastic Leukemia, Mature B-Cell

United States
Brigham and Women's Hospital

Not yet recruiting

Drug Screening Using IMD in Bladder Cancer

Muscle Invasive Bladder Urothelial Carcinoma

United States

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