Search clinical trials for: Methylnaltrexone IR capsule

Total 3840 results

University Medicine Greifswald

Completed

Effects of 500 mg Immediate Release and Extended Release Methylnaltrexone on Loperamide-induced Delay of the Oro-cecal and Whole-gut Transit Time in Healthy Subjects (LOP-MNTX-2009)

Intestinal Obstruction

Germany
GlaxoSmithKline

Completed

Bioavailability and Food Effect Study of Gelatin Formulation and Immediate Release Tablet Formulation of Afuresertib

Cancer

Australia
Bristol-Myers Squibb

Completed

A Study to Assess the Bioavailability and Effect of Food of BMS-986419 Immediate-release Tablet Formulation in Healthy Adult Participants

Healthy Volunteers

United States
Beijing Union Pharmaceutical Factory Ltd
R&G Pharma Studies Co.,Ltd.

Recruiting

Phase 3 Clinical Trial of Buagafuran Capsules in the Treatment of GAD (BGFN-2022-02)

Generalized Anxiety Disorder

China
Grünenthal GmbH

Completed

A Clinical Study in Healthy Women Which Aims to Explore the Intestinal Uptake of Two Different Tablets of GRTA9906 Into the Body and the Effect of Food on it

Pain | Chronic Pain | Neuropathic Pain | Visceral Pain

Germany
Shanghai Jiao Tong University School of Medicine
Shanghai Chest Hospital

Recruiting

Limonene for Pulmonary Nodule Chemoprevention

Pulmonary Nodules

China
Shire

Completed

Safety and Efficacy Study of SHP465 in Adults Aged 18-55 Years With Attention-deficit/ Hyperactivity Disorder (ADHD)

Attention Deficit Hyperactivity Disorder (ADHD)

United States
Reata, a wholly owned subsidiary of Biogen

Completed

RTA 408 Capsules in Patients With Melanoma - REVEAL

Melanoma | Unresectable (Stage III) Melanoma | Metastatic (Stage IV) Melanoma

United States
Reata, a wholly owned subsidiary of Biogen

Completed

Safety and PK/PD of RTA 1701 in Healthy Adults

Healthy

Australia
AstraZeneca

Withdrawn

A Study to Compare the Pharmacokinetics of Different Formulations of AZD9977 and the Influence of Food in Healthy Male Subjects

Healthy Male Subjects | Pharmacokinetics | Safety | Food Effect

United Kingdom
Hongsheng Tan
Shanghai Shen Kang Hospital Development Center; Longhua Hospital; Hongqiao International...

Completed

Limonene on Regulating Metabolism-related Fatty Liver Disease (MAFLD) and Analysis of TCM Constitution (DL-MAFLD-TCM)

Fatty Liver

China
Enzychem Lifesciences Corporation

Completed

EC-18 for Oral Mucositis in Patients With Concomitant Chemoirradiation

Stomatitis

United States
Bioxodes S.A.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Ir-CPI in Healthy Male Subjects

Healthy

Belgium
OPKO Health, Inc.

Completed

Safety/Efficacy Study of CTAP101 in Chronic Kidney Disease Subjects With Secondary Hyperparathyroidism (SHPT)

Chronic Kidney Disease | Secondary Hyperparathyroidism | Vitamin D Insufficiency

United States
First Affiliated Hospital Xi'an Jiaotong University

Unknown

A Clinical Study on the Efficacy and Safety of the Treatment of Hyperplasia of Mammary Glands With Xiaoru Sanjie Capsule

Fibrocystic Disease of Breast

China
Natrogen Therapeutics International, Inc

Unknown

Efficacy and Tolerability Study of Natura-Alpha in the Treatment of Patients With Active Ulcerative Colitis

Ulcerative Colitis

United States
TaiRx, Inc.

Completed

Safety and Pharmacokinetic Study of CVM-1118 Extended-Release in Advanced Cancer Patients

Advanced Cancer

Taiwan
Psychiatric Hospital of the University of Basel

Terminated

Fecal Microbiota Transplantation in Depression

Major Depressive Disorder

Switzerland
Medtronic - MITG

Terminated

Feasibility Study to Evaluate the Performance of Flocculation-Adsorption System for Colon Cleansing Enhancement (RD-400)

Healthy

Israel
Federal University of São Paulo

Unknown

Far-IR Emitted by Compression Stockings for Cellulitis Treatment

Quality of Life | Cellulitis
Bausch Health Americas, Inc.

Completed

Pharmacokinetics and Bioavailability of Single Subcutaneous Doses of Methylnaltrexone Versus Intravenous Dose

Healthy Subjects

United States
Massachusetts General Hospital
Center for Microbiome Informatics and Therapeutics

Active, not recruiting

Fecal Microbiota Transplant as Treatment of Hepatic Encephalopathy

Hepatic Encephalopathy

United States
Han Yaling

Completed

Tongxinluo Improve High on Clopidogrel Platelet Reactivity Patients With Coronary Heart Disease (Talent)

Coronary Artery Disease

China
POM Wonderful LLC

Completed

Safety and Efficacy of POMx Capsules in Men With Recurrent Prostate Cancer: An 18-Month Study

Recurrent Prostate Cancer

United States
Bausch Health Americas, Inc.

Completed

Safety and Gastrointestinal Effects of Intravenous Methylnaltrexone

Healthy Volunteers

United States
Beijing Tiantan Hospital
NeuroDawn Pharmaceutical Co., Ltd.

Recruiting

Efficacy and Safety of Minocycline in Patients With Moderate to Severe Acute Ischemic Stroke (EMPHASIS)

Ischemic Stroke, Acute

China
Yale University

Completed

Cranberry for UTI Prevention in Residents of Long Term Care Facilities (PACS)

Urinary Tract Infection

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

An Analysis of the Response of Human Tumor Microvascular Endothelium to Ionizing Radiation

Melanoma | Small Cell Lung Cancer | Colorectal Neoplasms | Ovarian Neoplasms | Liposarcoma

United States
Bausch Health Americas, Inc.

Completed

Pharmacokinetics, Safety, and Tolerability of Methylnaltrexone in Volunteers With Impaired Hepatic Function

Liver Dysfunction

United States
Bausch Health Americas, Inc.

Completed

Open-Label Treatment Extension of Protocol MNTX 302

Terminal Illness

United States
Pusan National University Hospital

Completed

Efficacy of Fenugreek Seed and Lespedeza Cuneata in TDS

Hypogonadism

Korea, Republic of
Bioxodes S.A.

Recruiting

A Study to Evaluate the Safety, Tolerability and the Effects of Ixodes Ricinus-Contact Phase Inhibitor (Ir-CPI) in Adult Patients With Spontaneous Intracerebral Haemorrhage (BIRCH)

Intracerebral Hemorrhage

Belgium
Al-Kindy College of Medicine

Completed

The Effect of Cinnamon on Patients With Chronic Prostatitis/Chronic Pelvic Pain Syndrome; a Pilot Study

Chronic Prostatitis | Chronic Pelvic Pain Syndrome

Iraq
Medibiofarma S.L.

Completed

Study to Assess the Safety and Tolerability of MBF-118 in Healthy Volunteers

Cancer

Spain
Bausch Health Americas, Inc.

Completed

Study of the Pharmacokinetics of Intravenous Administered 14C-MNTX

Healthy Male Volunteers

United States
Bausch Health Americas, Inc.

Completed

Study of Pharmacokinetics, Safety and Tolerability of Intravenous Methylnaltrexone Bromide

Healthy Adults

United States
GlaxoSmithKline

Completed

A 5-Period, Single Dose, Phase 1 Study in Healthy Elderly Subjects to Assess Relative Bioavailability and Food Effect of Two Oral Formulations of GSK1325756 (Free Base vs HBr Salt) and Food Effect on the HBr Formulation When Given With Omeprazole

Pulmonary Disease, Chronic Obstructive

United States
Bausch Health Americas, Inc.

Completed

Tolerance and Pharmacokinetics Study of MNTX Tablets

Normal Healthy Volunteers

United States
Bausch Health Americas, Inc.

Completed

Pharmacokinetics, Safety, and Tolerability of Methylnaltrexone (MNTX) in Subjects With Impaired Renal Function

Renal Impairment

United States
Stallergenes Greer

Completed

Efficacy & Safety of STG320 Sublingual Tablets of HDM Allergen Extracts in Adults and Adolescents With HDM-associated AR

Rhinitis, Allergic, Perennial | House Dust Mite Allergy

France, United States
POM Wonderful LLC
Target Health Inc.

Completed

POMx In the Treatment of Erectile Dysfunction

Erectile Dysfunction

United States
Landos Biopharma Inc.

Completed

Safety, Tolerability, and Pharmacokinetics of Oral NX-13 in Active Ulcerative Colitis

Ulcerative Colitis

United States, Ukraine
F2G Biotech GmbH
Quotient Clinical

Completed

Evaluation of Immediate Release Tablet

Invasive Aspergillosis

United Kingdom
Institut Pasteur de Lille
Luxomed

Terminated

Interest in the Medium Term of an Infrared Reflexotherapy on Overweight or Class I Obese People (REFLEX-IR)

Assess the Effect of an IR Reflexotherapy on Overweight and Class I Obese People

France
Bristol-Myers Squibb

Completed

Multiple Dose Study In Cancer Patients: Safety and Tolerability of BMS-754807 in Advanced or Metastatic Solid Tumors

Neoplasms | Solid Tumors | Metastases

Australia
Bausch Health Americas, Inc.
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study of Methylnaltrexone (MNTX) for the Relief of Constipation

Advance Illness Patients With OIC

United States
BioDelivery Sciences International

Completed

Evaluation of the Tolerability of Switching Subjects on Chronic ATC Opioid Therapy to Buprenorphine HCl Buccal Film

Pain

United States
University of Rochester
Stanford University

Recruiting

Breathing, Relaxation, Attention Training, & Health in Older Adults (BREATHE)

Healthy Aging | Mild Cognitive Impairment

United States
Bausch Health Americas, Inc.

Completed

Open-Label Treatment Extension of Protocol MNTX 301

Terminal Illness

United States
Bausch Health Americas, Inc.

Completed

Effect of Cimetidine on the Single-Dose PK of IV- Administered MNTX

Healthy Adult Subjects

United States

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