Search clinical trials for: Modufolin (arfolitixorin)

Total 12 results

Isofol Medical AB

Completed

Study Evaluating ECG Effects, Safety, Tolerability and Pharmacokinetics of Single Doses of Modufolin (Arfolitixorin) in Healthy Volunteers Tetrahydrofolate in Healthy Male Volunteers

Phase I Study in Healthy Volunteers to Evaluate ECG Effect

Sweden
Isofol Medical AB

Completed

An Extended Feasibility Phase I/II Study of Methylenetetrahydrofolate (Arfolitixorin) and Pemetrexed Single Agent, Given as Neoadjuvant Treatment in Patients With Resectable Rectal Cancer

Rectal Cancer

Sweden
Isofol Medical AB

Completed

PK/PD Investigation of Modufolin (Arfolitixorin) in Plasma, Tumor and Adjacent Mucosa Adjacent Mucosa in Patients With Colon Cancer

Colonic Neoplasms

Sweden
Isofol Medical AB

Completed

Investigation of [6R] 5,10-methylenetetrahydrofolate (Arfolitixorin) as Rescue Therapy for Osteosarcoma Patients Treated With HDMTX.

Osteosarcoma

Poland, Czechia, Hungary, Sweden
Vastra Gotaland Region
Isofol Medical AB

Unknown

Modelle 001, TS-inhibition in Colorectal Liver Metastases Comparing Arfolitixorin and Calciumfolinate

Metastatic Colorectal Cancer

Sweden
University of Miami

Recruiting

Clinical Applications of Advanced Ophthalmic Imaging

Multiple Sclerosis | Diabetic Retinopathy | Dementia | Dry Eye Syndromes | Presbyopia | Myopia

United States
Isofol Medical AB

Completed

A Study to Compare the Efficacy of Arfolitixorin Versus Leucovorin in Combination With 5 Fluorouracil, Oxaliplatin, and Bevacizumab in Patients With Advanced Colorectal Cancer (AGENT)

Colo-rectal Cancer

United States, Australia, Austria, Canada, France, Germany, Greece, Japan, Spain, Sweden
Devogelaere Vision

Completed

Effect of Vitamin Supplementation in Glaucoma Patients

Glaucoma | Homocysteinemia | Elevated Retinal Venous Pressure | Abnormal Steady State Pattern Electroretinography

Belgium
Medical University of Vienna
Aprofol AG

Completed

A Study to Assess the Effect of a 3-month Folate Supplementation on Systemic Homocysteine Plasma Concentration and Ocular Blood Flow in Patients With Diabetes

Diabetes

Austria
Isofol Medical AB

Completed

Modufolin (Arfolitixorin) in Combination With 5-Fluorouracil Alone or Together With Oxaliplatin or Irinotecan in Colorectal Cancer

Colorectal Neoplasm

Denmark, Norway, Greece, Sweden
Maastricht University Medical Center

Recruiting

Cognitive Effects of Roflumilast in (a)MCI and Mild Dementia Patients (ROMEMA)

Mild Cognitive Impairment | Mild Dementia | Amnestic Mild Cognitive Disorder

Netherlands
Eli Lilly and Company
Alkermes, Inc.

Completed

A Study for Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Japan

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