Search clinical trials for: NUC-3373 leucovorin

Total 2608 results

University of Oxford

Completed

NUC-3373 in Advanced Solid Tumours (NuTide:301)

Cancer

United Kingdom
NuCana plc

Completed

A Safety, Pharmacokinetic and Efficacy Study of NUC-3373 in Combination With Standard Agents Used in Colorectal Cancer Treatment

Colorectal Neoplasms | Colorectal Cancer | Colorectal Tumors | Colorectal Carcinoma | Neoplasms, Colorectal

United States, France, United Kingdom
National Enzyme Company

Unknown

Study to Investigate the Efficacy of Digestive Enzymes on Inflammation After a Meal

Post Prandial Inflammation Markers

Canada
NuCana plc

Recruiting

NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours

Melanoma | Renal Cell Carcinoma | Gastric Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | Advanced Cancer | Head and Neck Squamous Cell Carcinoma | Endometrial Carcinoma | Urothelial Carcinoma | Classical Hodgkin Lymphoma | Neoplasm Malignant | Pleural... and other conditions

United Kingdom
The Hospital for Sick Children
SickKids Foundation; The Cundill Centre for Child and Youth Depression

Unknown

Focused Suicide Prevention Strategy for Youth (FSPS)

Suicidal Ideation | Suicide, Attempted | Suicide

Canada
NuCana plc

Terminated

NUC-1031 in Patients With Platinum-Resistant Ovarian Cancer

Ovarian Cancer

United States, United Kingdom
AbbVie

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of ABBV-3373 in Participants With Moderate to Severe Rheumatoid Arthritis (RA)

Rheumatoid Arthritis (RA)

United States, Germany, Hungary, Israel, Netherlands, Poland, Puerto Rico
Imperial College London
Nucana

Completed

NUC-1031 in Patients With Advanced Solid Tumours (ProGem1)

Cancer

United Kingdom
Dr. Falk Pharma GmbH

Recruiting

norUrsodeoxycholic Acid vs Placebo in PSC

Primary Sclerosing Cholangitis

Austria, Germany
Tengion

Completed

Incontinent Urinary Diversion Using an Autologous Neo-Urinary Conduit

Bladder Cancer

United States
Abbott

Completed

Bioavailability of ABT-333 Tablet Versus First in Human (FIH) Capsule Formulation and Safety, Tolerability and PK Study of Single Doses of ABT-333 in Healthy Volunteers

HCV Infection

United States
Kissei Pharmaceutical Co., Ltd.

Completed

An Extension Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD)

Spinocerebellar Degeneration

Japan
Polichem S.A.

Completed

Study to Evaluate the Efficacy and Safety of P-3073 Nail Solution in the Treatment of Nails Affected by Psoriasis

Nail Psoriasis

Czechia, Russian Federation, Germany, Greece, Poland, Bulgaria, Latvia
Kissei Pharmaceutical Co., Ltd.

Completed

A 24-week Open-label Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD)

Spinocerebellar Degeneration

Japan
Kissei Pharmaceutical Co., Ltd.

Completed

A Long-Term Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD)

Spinocerebellar Degeneration

Japan
NuCana plc

Active, not recruiting

A Study of NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer

Colorectal Neoplasms | Colorectal Cancer | Colorectal Cancer Metastatic | Colorectal Adenocarcinoma | Neoplasm, Colorectal

United States, Spain, United Kingdom, Italy, Germany, France
Kissei Pharmaceutical Co., Ltd.

Completed

An Additional Confirmatory Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD)

Spinocerebellar Degeneration

Japan
Dart NeuroScience, LLC

Terminated

DNS-3379 vs. Placebo in Stroke Rehabilitation (SPIRIT)

Ischemic Stroke

Australia, New Zealand
Kissei Pharmaceutical Co., Ltd.

Completed

A Confirmatory Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD)

Spinocerebellar Degeneration

Japan
SWOG Cancer Research Network
National Cancer Institute (NCI); Halozyme Therapeutics

Completed

S1313, PEGPH20 in Treating Patients With Newly Diagnosed Metastatic Pancreatic Cancer

Metastatic Pancreatic Adenocarcinoma

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S1201: Combination Chemo for Patients W/Advanced or Metastatic Esophageal, Gastric, or Gastroesophageal Junction Cancer

Gastric Cancer | Esophageal Cancer | Adenocarcinoma of the Gastroesophageal Junction

United States
Polichem S.A.
Almirall, S.A.

Withdrawn

Study to Evaluate the Efficacy and Safety of P-3073 Nail Solution in the Treatment of Mild to Moderate Psoriatic Fingernail/s

Nail Psoriasis

United States
Charite University, Berlin, Germany

Completed

FLO +/- Pazopanib as First-line Treatment in Advanced Gastric Cancer (PaFLO)

Advanced Gastric Cancer

Germany
Quigley Pharma, Inc.

Completed

Safety and Efficacy Study of QR-333 in Patient's With Symptomatic Diabetic Neuropathy

Diabetic Neuropathy

United States
Kissei Pharmaceutical Co., Ltd.

Completed

Phase II Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD)

Spinocerebellar Degeneration

Japan
Chong Kun Dang Pharmaceutical

Unknown

Compare the Pharmacokinetics and Safety of CKD-333 With Co-administration CKD-330 and D090 in Healthy Male Adults

Hypertension | Dyslipidemias

Korea, Republic of
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; Cancer and... and other collaborators

Completed

S9415 Chemotherapy in Patients With Stage II or III Colon Cancer That Has Been Surgically Removed

Colorectal Cancer

United States, Canada, South Africa, Puerto Rico
Amgen

Completed

A Phase 1/2 Study Evaluating AMG 337 in Asian Subjects

Stomach Neoplasms

Japan
Sosei

Completed

A Multicentre Trial to Determine the Efficacy and Safety of AD-337 in the Treatment of Fibromyalgia

Fibromyalgia

United Kingdom
Amgen

Terminated

Phase 2 Study of AMG 337 in MET Amplified Gastric/Esophageal Adenocarcinoma or Other Solid Tumors

Stomach Neoplasms

Belgium, France, Italy, Spain, Czechia, Poland, United States, Korea, Republic of, Russian Federation, Canada, United Kingdom, Australia, Austria, Germany, Hungary, Greece, Peru, Chile
AbbVie

Completed

Bioavailability of ABT-333 Within the Gastrointestinal Tract in Healthy Subjects

Relative Bioavailability

United Kingdom
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating SRA-333 in Mild to Moderate Alzheimer's Disease (AD)

Alzheimer's Disease

United States
AbbVie

Completed

Study of ABT-333 in Both Healthy Volunteers and Hepatitis C Virus (HCV) + Genotype 1 Infected Subjects

HCV Infection
Abbott
Abbott Japan Co.,Ltd

Completed

A Study of Single Dose of ABT-333 in Healthy Male Adults

HCV Infections

Japan
Abbott

Completed

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Multiple Ascending Doses of the ABT-333 Tablet

HCV Infection

United States
Kissei Pharmaceutical Co., Ltd.

Completed

A Phase II Double Blind Comparative Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD)

SCD

Japan
Kissei Pharmaceutical Co., Ltd.

Completed

A Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD)

Spinocerebellar Degeneration

Japan
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S9700 Combination Chemotherapy in Treating Patients With Stage II or Stage III Pancreatic Cancer

Pancreatic Cancer

United States
Imperial College Healthcare NHS Trust

Completed

Safety and Efficacy Study of Nuc-1031 and Carboplatin Combination to Treat Recurrent Ovarian Cancer (ProGem2)

Recurrent Ovarian Cancer

United Kingdom
Nobelpharma

Completed

An Additional Study of NPC-22 in Healthy Adult Males

Safety and Pharmacokinetics

Japan
Nobelpharma

Completed

A Study of NPC-22 in Healthy Adult Males

Healthy Adult Subjects

Japan
Amgen

Terminated

Phase I, Double-Blind,Placebo, MAD Study to Evaluate the Safety, Tolerability, PK, and PD of AMG 333 in Healthy Subjects and Migraine Subjects

Migraine

United States
Amgen

Completed

Single-Ascending Dose Study of AMG 333 in Healthy Subjects and Subjects With Migraines

Migraine

United States
Haruhiko Fukuda
Ministry of Health, Labour and Welfare, Japan

Completed

A Trial Comparing Adjuvant Oral UFT/LV to 5-FU/l-LV in Stage III Colorectal Cancer (JCOG-0205-MF)

Colorectal Neoplasms

Japan
Nobelpharma

Completed

A Study for Kidney Transplant Recipients at High-Risk of Cytomegalovirus Infection

Cytomegalovirus Disease

United States, Japan
Kowa Company, Ltd.

Completed

Study of Peretinoin for Suppressing Recurrence of HCV-positive HCC

Hepatic Neoplasm Malignant Recurrent

Japan
Chong Kun Dang Pharmaceutical

Completed

Pharmacokinetics and Safety Profile of CKD-333

Hypertension | Dyslipidemias

Korea, Republic of
Eastern Cooperative Oncology Group
National Cancer Institute (NCI); ECOG-ACRIN Cancer Research Group

Withdrawn

C-Met Inhibitor AMG 337, Oxaliplatin, Leucovorin Calcium, and Fluorouracil in Treating Patients With Advanced Stomach or Esophageal Cancer

Gastrointestinal Cancer | Adenocarcinoma of the Gastroesophageal Junction | Stage IV Gastric Cancer | Adenocarcinoma of the Esophagus | Stage IV Esophageal Cancer | Diffuse Adenocarcinoma of the Stomach | Intestinal Adenocarcinoma of the Stomach | Mixed Adenocarcinoma of the Stomach | Stage IIIA Gastric... and other conditions

United States
Hoffmann-La Roche

Recruiting

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7565020 in Healthy Participants and in Participants With Chronic Hepatitis B Virus Infection

Chronic Hepatitis B

Korea, Republic of, United States, Thailand, Hong Kong, Spain, New Zealand, Bulgaria, Taiwan, France
Rush University Medical Center
Pamlab, Inc.

Completed

Study of the Effects of Cerefolin NAC on Inflammation Blood Markers in Older Individuals With Memory Complaints

Subjective Memory Loss in Older Persons

United States

Search clinical trials for: NUC-3373 leucovorin

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