Search clinical trials for: Nalmefene

Total 35 results

Somaxon Pharmaceuticals

Completed

Nalmefene Gambling Study: Study of Nalmefene HCl in the Treatment of Pathological Gambling

Pathological Gambling
Otsuka Pharmaceutical Co., Ltd.
H. Lundbeck A/S

Completed

A Single-center, Open-label, Single-dose Study Investigating the Safety, Tolerability, and Pharmacokinetic Properties of Nalmefene 10 mg Tablets in Healthy Japanese Male Subjects

Alcohol Dependence

Japan
H. Lundbeck A/S

Completed

Effects of Nalmefene After Single Dose on the Blood Oxygen Level Dependent (BOLD) fMRI Signal in the Ventral Striatum to Reward Responding in the Monetary Incentive Delay Task (MIDT), in Non-treatment Seeking Subjects With Alcohol Dependence Following Alcohol Challenge

Alcohol Dependence

United Kingdom
Somaxon Pharmaceuticals

Completed

Nalmefene Smoking Cessation Study

Smoking Cessation

United States
Opiant Pharmaceuticals Inc

Completed

Pharmacokinetic Evaluation of Intranasal Nalmefene Using Three Dosing Regimens

Opioid Overdose

United States
Opiant Pharmaceuticals Inc

Completed

Pharmacokinetic Evaluation of Intranasal Nalmefene

Pharmacokinetics

United States
Otsuka Pharmaceutical Co., Ltd.
H. Lundbeck A/S

Completed

A Long-term Extension Study for the Phase 3 Study of Nalmefene (339-14-001) in Patients With Alcohol Dependence

Alcohol Dependence

Japan
H. Lundbeck A/S

Completed

Pharmacokinetic Properties of Nalmefene in Subjects With Renal Impairment and in Healthy Subjects

Renal Impairment

Germany
Otsuka Pharmaceutical Co., Ltd.

Active, not recruiting

Post-Marketing Surveillance Study of Nalmefene Hydrochloride Hydrate in Patients With Alcohol Dependence

Alcohol Dependence

Japan
Otsuka Pharmaceutical Co., Ltd.
H. Lundbeck A/S

Completed

A Multicenter, Randomized, Double-blind, Placebo-controlled, 3-parallel-group Comparison Trial to Investigate the Effect of Nalmefene on Alcohol Consumption Reduction in Patients With Alcohol Dependence (Phase 3 Trial)

Alcohol Dependence

Japan
Opiant Pharmaceuticals Inc

Completed

Pharmacodynamic Evaluation of Intranasal Nalmefene

Pharmacodynamic

United States
H. Lundbeck A/S

Completed

Treatment of Patients Suffering of Alcohol Dependence and Impaired Liver Function With Selincro® As-needed Use

Alcohol Dependence

Germany
Purdue Pharma LP

Withdrawn

Clinical Outcomes From Nalmefene (COINED)

Opioid Overdose
Centre Hospitalier Universitaire, Amiens

Withdrawn

Nalmefene in Patients With Alcoholic Compensated Cirrhosis for the Treatment of Alcohol Dependence. (NalmeCir)

Alcohol Dependence | Cirrhosis | Nalmefene

France
United BioPharma
Kaohsiung Medical University Chung-Ho Memorial Hospital; Taipei Veterans General... and other collaborators

Completed

To Investigate the Safety and Efficacy of UB-421 Monotherapy in HIV Infected Adults

HIV-1 Infection

Taiwan
H. Lundbeck A/S

Terminated

Study of 18 mg Selincro® As-needed Use, in the Treatment of Patients With Alcohol Dependence in Primary Care

Alcohol Dependence

France, Germany, Spain, United Kingdom
National Institute on Drug Abuse (NIDA)

Completed

Pharmacokinetic Evaluation of Nalmefene Administered Intranasally to Healthy Volunteers

Opioid-Related Disorders

United States
National Jewish Health

Completed

FiteBac Hand Sanitizer in the Management of Hand Dermatitis in Adults (FiteBac)

Hand Dermatitis

United States
Tharimmune Inc

Active, not recruiting

An Evaluation of The Absolute Bioavailability of TH104

Healthy

United States
University Hospital, Clermont-Ferrand

Unknown

Evaluation of Nalmefene in Impulse Control Disorders in Parkinson's Disease: A Prospective Open Label Study (Nalmefene TCI)

Parkinson Disease | Impulse Control Disorders

France
Nantes University Hospital

Recruiting

NAlmefene Versus Placebo in Addition to Treatment as Usual on Craving in Behavioural Addictions (NABAb)

Behavioural Addiction

France
RenJi Hospital
Shanghai Tong Ren Hospital; The First Affiliated Hospital of Zhengzhou University and other collaborators

Recruiting

Effect of Nalmefene on the Quality of Resuscitation in Patients Under General Anesthesia

Resuscitation

China
National Institute on Alcohol Abuse and Alcoholism...

Completed

Title: Effect of Opioid Receptor Modulation on Alcohol Self-Administration and Neural Response to Alcohol Cues in Heavy Drinkers: Role of OPRM1 Gene Variation

AUD

United States
Central Institute of Mental Health, Mannheim
Lundbeck GmbH, Ericusspitze 2, 20457 Hamburg

Terminated

Single-dose of Nalmefene to Modulate Neural Alcohol Cue Reactivity (NALCUE)

Alcoholism

Germany
H. Lundbeck A/S

Completed

Efficacy of Nalmefene in Patients With Alcohol Dependence (ESENSE2)

Alcohol Dependence

Poland, Belgium, Czech Republic, France, Italy, Portugal, Spain
Fundació Institut de Recerca de l'Hospital de la...
Hospital Universitari General de Catalunya

Unknown

Nalmefene in Alcohol Dependence and Borderline Personality Disorder

Borderline Personality Disorder | Alcohol Use Disorder

Spain
H. Lundbeck A/S

Completed

Safety and Efficacy of Nalmefene in Patients With Alcohol Dependence (SENSE)

Alcohol Dependence

Poland, Russian Federation, Ukraine, Czech Republic, Estonia, Hungary, Latvia, Lithuania, Slovakia, United Kingdom
H. Lundbeck A/S

Completed

Efficacy of Nalmefene in Patients With Alcohol Dependence (ESENSE1)

Alcohol Dependence

Austria, Finland, Germany, Sweden
University of Bordeaux
Lundbeck France

Completed

Use of Selincro and Impact on Usual Practice (USE-PACT)

Alcohol Dependence

France
Yale University
First Pavlov State Medical University in St. Petersburg, Russia

Completed

Patient Driven Recovery With Nalmefene and Coaching

Opioid-use Disorder | Harmful; Use, Alcohol

United States
Boston Medical Center
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

St. PETERsburg Pain and Alcohol Intervention With Naltrexone and Nalmefene (PETER PAIN)

HIV Infection | Pain | Alcohol Use

Russian Federation
Baskent University

Completed

Effects of a Cyclic NSAID Regimen on Levels of GCF PGE-E2 and IL-1beta

Non-steroidal Anti-inflammatory Poisoning
Prof. Daniele Zullino

Completed

Nalmefene, Baclofen and Impulsivity in Subjects With Alcohol Use Disorder and Healthy Control Subjects

Alcohol Use Disorder

Switzerland
Tianjin Medical University General Hospital

Completed

Effect of Dexmedetomidine Combined With Low-dose Nalmefene on Preventing Remifentanil-induced Postoperative Hyperalgesia

Pain | Anesthesia

China
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Olanzapine With or Without Fosaprepitant Dimeglumine in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Receiving Highly Emetogenic Chemotherapy

Malignant Neoplasm

United States, Guam

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