Search clinical trials for: Nalmefene Hydrochloride Hydrate

Total 7673 results

Otsuka Pharmaceutical Co., Ltd.

Active, not recruiting

Post-Marketing Surveillance Study of Nalmefene Hydrochloride Hydrate in Patients With Alcohol Dependence

Alcohol Dependence

Japan
Opiant Pharmaceuticals Inc

Completed

Pharmacodynamic Evaluation of Intranasal Nalmefene

Pharmacodynamic

United States
Purdue Pharma LP

Withdrawn

Clinical Outcomes From Nalmefene (COINED)

Opioid Overdose
Otsuka Pharmaceutical Co., Ltd.
H. Lundbeck A/S

Completed

A Single-center, Open-label, Single-dose Study Investigating the Safety, Tolerability, and Pharmacokinetic Properties of Nalmefene 10 mg Tablets in Healthy Japanese Male Subjects

Alcohol Dependence

Japan
Opiant Pharmaceuticals Inc

Completed

Pharmacokinetic Evaluation of Intranasal Nalmefene Using Three Dosing Regimens

Opioid Overdose

United States
Opiant Pharmaceuticals Inc

Completed

Pharmacokinetic Evaluation of Intranasal Nalmefene

Pharmacokinetics

United States
Otsuka Pharmaceutical Co., Ltd.
H. Lundbeck A/S

Completed

A Long-term Extension Study for the Phase 3 Study of Nalmefene (339-14-001) in Patients With Alcohol Dependence

Alcohol Dependence

Japan
Otsuka Pharmaceutical Co., Ltd.
H. Lundbeck A/S

Completed

A Multicenter, Randomized, Double-blind, Placebo-controlled, 3-parallel-group Comparison Trial to Investigate the Effect of Nalmefene on Alcohol Consumption Reduction in Patients With Alcohol Dependence (Phase 3 Trial)

Alcohol Dependence

Japan
Marian Macsai, MD

Recruiting

Glanatec(R) for Descemet Stripping in Fuch's Endothelial Dystrophy

Fuchs' Endothelial Dystrophy

United States
Somaxon Pharmaceuticals

Completed

Nalmefene Gambling Study: Study of Nalmefene HCl in the Treatment of Pathological Gambling

Pathological Gambling
H. Lundbeck A/S

Completed

Effects of Nalmefene After Single Dose on the Blood Oxygen Level Dependent (BOLD) fMRI Signal in the Ventral Striatum to Reward Responding in the Monetary Incentive Delay Task (MIDT), in Non-treatment Seeking Subjects With Alcohol Dependence Following Alcohol Challenge

Alcohol Dependence

United Kingdom
Somaxon Pharmaceuticals

Completed

Nalmefene Smoking Cessation Study

Smoking Cessation

United States
Philadelphia Department of Public Health
Children's Hospital of Philadelphia; Stanford University

Completed

Increasing Water Access and Appeal in Community Recreation Centers (Hydrate Philly)

Health Behavior

United States
Cancer Research UK

Active, not recruiting

A CR-UK Phase I Trial of LY3143921

a. Colorectal Cancer | b. High Grade Serous Ovarian Cancer | c. Non Small-cell Lung Cancer (Squamous Cell Variant) | d. Squamous Carcinoma of the Oesophagus | e. Squamous Carcinoma of the Head and Neck (HPV Negative) | f. Urothelial Cancer | g. Breast Cancer (Triple Negative Type) | h. Pancreatic...

United Kingdom
Pfizer

Recruiting

Special Investigation for VIZIMPRO Tablets (Secondary Data Collection Study; Safety and Efficacy of VIZIMPRO Under Japanese Medical Practice)

EGFR Mutation-positive Inoperable or Reccrent NSCLC

Japan
H. Lundbeck A/S

Completed

Pharmacokinetic Properties of Nalmefene in Subjects With Renal Impairment and in Healthy Subjects

Renal Impairment

Germany
H. Lundbeck A/S

Completed

Treatment of Patients Suffering of Alcohol Dependence and Impaired Liver Function With Selincro® As-needed Use

Alcohol Dependence

Germany
Sun Yat-sen University

Completed

Comparison Between Oral and Enema of Chloral Hydrate

Congenital Cataract
National Cancer Institute (NCI)

Completed

Berberine Chloride in Preventing Colorectal Cancer in Patients With Ulcerative Colitis in Remission

Ulcerative Colitis

United States, China
Centre Hospitalier Universitaire, Amiens

Withdrawn

Nalmefene in Patients With Alcoholic Compensated Cirrhosis for the Treatment of Alcohol Dependence. (NalmeCir)

Alcohol Dependence | Cirrhosis | Nalmefene

France
Aerie Pharmaceuticals

Completed

Efficacy and Safety Study of Netarsudil 0.02% Ophthalmic Solution Compared to Ripasudil Hydrochloride Hydrate 0.4% Ophthalmic Solution in Japanese Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

Japan
Astellas Pharma Inc
FibroGen

Completed

A Drug Interaction Study to Evaluate the Pharmacokinetics of ASP1517 and Lanthanum Carbonate Hydrate

Healthy Subjects

Japan
United BioPharma
Kaohsiung Medical University Chung-Ho Memorial Hospital; Taipei Veterans General... and other collaborators

Completed

To Investigate the Safety and Efficacy of UB-421 Monotherapy in HIV Infected Adults

HIV-1 Infection

Taiwan
Merck Sharp & Dohme LLC

Completed

Bioequivalence of Two Tablet Forms of MK0974 (0974-045)

Migraine
H. Lundbeck A/S

Terminated

Study of 18 mg Selincro® As-needed Use, in the Treatment of Patients With Alcohol Dependence in Primary Care

Alcohol Dependence

France, Germany, Spain, United Kingdom
University of Florida
National Institutes of Health (NIH)

Completed

Pharmacotoxicology of Trichloroethylene Metabolites

Healthy

United States
Yonsei University

Completed

Effects of Chloral Hydrate on Induction, Maintenance, and Recovery From Sevoflurane Anesthesia in Day-case Pediatric Surgery

Pediatric

Korea, Republic of
Zeria Pharmaceutical

Recruiting

A Phase III Trial of Z-338 in Paediatric Patients With Functional Dyspepsia

Functional Dyspepsia

Japan
Agios Pharmaceuticals, Inc.

Completed

A Study to Compare the Pharmacokinetics and Safety of Mitapivat 100 mg Tablet Formulation With Mitapivat 2 × 50 mg Tablet Formulation in Healthy Adult Participants

Healthy Volunteers

United States
Fr Muller Homoeopathic Medical College
Father Muller Medical College

Unknown

A Clinical Study on Causticum 200 Centesimal Potency in Primary Enuresis (PE)

Bed Wetting | Primary Enuresis

India
National Cancer Institute (NCI)

Active, not recruiting

Gemcitabine Hydrochloride, Dasatinib, and Erlotinib Hydrochloride in Treating Patients With Pancreatic Cancer That Is Metastatic or Cannot Be Removed by Surgery

Metastatic Pancreatic Adenocarcinoma | Recurrent Pancreatic Carcinoma | Stage III Pancreatic Cancer AJCC v6 and v7 | Stage IV Pancreatic Cancer AJCC v6 and v7

United States
Ono Pharmaceutical Co. Ltd
Astellas Pharma Inc

Completed

Controlled Study of ONO-5920 in Patients With Involutional Osteoporosis in Japan

Involutional Osteoporosis

Japan
National Institute on Drug Abuse (NIDA)

Completed

Pharmacokinetic Evaluation of Nalmefene Administered Intranasally to Healthy Volunteers

Opioid-Related Disorders

United States
National Jewish Health

Completed

FiteBac Hand Sanitizer in the Management of Hand Dermatitis in Adults (FiteBac)

Hand Dermatitis

United States
Cairo University

Completed

Effect of Intracameral Injection of Mydriatic Plus Anaesthetic Combination on Corneal Endothelial Count in Phaco

Cataract | Corneal Endothelial Cell Loss | Mydriasis

Egypt
Assiut University

Completed

Comparison of Postoperative Analgesic Efficacy of Caudal Block Versus Spinal Block With Levobupivacaine for Inguinal Hernia in Children

Pain, Postoperative | Analgesia

Egypt
Amir Safwat

Completed

The Bio-Clinical Effects of the (Sacubitril-Valsartan) Combination on Patients With Chronic Heart Failure

Heart Failure

Egypt
Tharimmune Inc

Active, not recruiting

An Evaluation of The Absolute Bioavailability of TH104

Healthy

United States
University Hospital, Clermont-Ferrand

Unknown

Evaluation of Nalmefene in Impulse Control Disorders in Parkinson's Disease: A Prospective Open Label Study (Nalmefene TCI)

Parkinson Disease | Impulse Control Disorders

France
Nantes University Hospital

Recruiting

NAlmefene Versus Placebo in Addition to Treatment as Usual on Craving in Behavioural Addictions (NABAb)

Behavioural Addiction

France
Helixmith Co., Ltd.

Completed

The Efficacy and Safety of TADIOS as an Adjuvant Therapy in Patients Diagnosed With Mild to Moderate COVID-19

COVID-19

India
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Completed

Metformin and Dietary Restriction to Prevent Age-related Morbid Events in People With Metabolic Syndrome (MeMeMe)

Metabolic Syndrome

Italy
University of Nottingham

Completed

Hydration and Outcome in Older Patients (HOOP)

Dehydration

United Kingdom
RenJi Hospital
Shanghai Tong Ren Hospital; The First Affiliated Hospital of Zhengzhou University and other collaborators

Recruiting

Effect of Nalmefene on the Quality of Resuscitation in Patients Under General Anesthesia

Resuscitation

China
Eli Lilly and Company

Completed

Effects of LY450139 Dihydrate on Subjects With Mild to Moderate Alzheimer's Disease

Alzheimer's Disease

United States
Dermofarm, S.A.U

Completed

Efficacy and Safety of a Hyaluronic Acid-Based Vaginal Moisturizer Medical Device to Ease Symptoms of Vaginal Dryness (HYALU-LAUDE)

Vaginal Disease

Spain
National Institute on Alcohol Abuse and Alcoholism...

Completed

Title: Effect of Opioid Receptor Modulation on Alcohol Self-Administration and Neural Response to Alcohol Cues in Heavy Drinkers: Role of OPRM1 Gene Variation

AUD

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Suspended

Copanlisib and Venetoclax for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma

Recurrent Mantle Cell Lymphoma | Refractory Mantle Cell Lymphoma

United States
Central Institute of Mental Health, Mannheim
Lundbeck GmbH, Ericusspitze 2, 20457 Hamburg

Terminated

Single-dose of Nalmefene to Modulate Neural Alcohol Cue Reactivity (NALCUE)

Alcoholism

Germany
Catholic University of the Sacred Heart
Sunstar Italiana SRL.

Completed

GUM Hydral Mouthwash vs Placebo in the Management of Hyposalivation.

Xerostomia | Xerostomia Following Radiotherapy

Italy

3

Subscribe