Search clinical trials for: Naloxone hydrochloride

Total 7620 results

Samjin Pharmaceutical Co., Ltd.

Completed

A Phase 4 Clinical Study to Investigate the Efficacy and Safety of Naloxone HCI IV in Patients With Stroke

Stroke, Acute

Korea, Republic of
Finnish Institute for Health and Welfare

Completed

Treatment of Gambling Disorder With Fast Acting Opiate Antagonist, Naloxone Nasal Spray (NALPILO)

Naloxone | Gambling | Spray | Opioid

Finland
Opiant Pharmaceuticals Inc

Completed

Pharmacodynamic Evaluation of Intranasal Nalmefene

Pharmacodynamic

United States
Leiden University Medical Center
U.S. Food and Drug Administration (FDA)

Recruiting

Reversal of Opioid-induced Respiratory Depression With Opioid Antagonists (ROAR)

Chronic Opioid Use | Opioid Induced Respiratory Depression

Netherlands
Indivior Inc.

Completed

A Randomized Acceptability and Safety Study of the Transfer From Subutex to Suboxone in Opioid- Dependent Subjects (Study P04843)(COMPLETED)

Opiate Dependence | Drug Dependence
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Unknown

Naloxone in Treating Constipation in Patients Who Are Receiving Opioids for Chronic Pain

Unspecified Adult Solid Tumor, Protocol Specific | Constipation, Impaction, and Bowel Obstruction

United States
Purdue Pharma LP

Withdrawn

Clinical Outcomes From Nalmefene (COINED)

Opioid Overdose
King's College London

Unknown

Buccal Versus Injectable Naloxone: a Phase I Healthy Volunteer Study

Opioid-Related Disorders | Drug Overdose
Mundipharma Pharmaceuticals B.V.

Completed

Oxycodone/Naloxone (OXN) Combination in Moderate to Severe Non-malignant Pain

Pain

Netherlands
Pfizer

Completed

Bioavailability Study of Naloxone 5 Milligrams (mg) Intramuscular (IM) Autoinjector

Healthy Volunteers

United States
Elorac, Inc.

Terminated

Naloxone Hydrochloride Study for Relief of Pruritus in Patients With MF or SS Forms of CTCL

Lymphoma, T-Cell, Cutaneous | Mycosis Fungoides | Sézary Syndrome

United States
Seema Capoor

Completed

Topical Naloxone to Diagnose Ocular Pain

Dry Eye Syndromes | Neuropathic Pain

United States
Finnish Institute for Health and Welfare

Unknown

Effects of Intranasal Naloxone on Gambling Urges and Craving in Gambling Disorder (NalGamb)

Naloxone | Gambling Disorder | Opioid Antagonist | Pathological Gambling

Finland
University of Maryland, Baltimore

Recruiting

Neural Correlates of Hypoalgesia Driven by Observation

Pain | Virtual Reality | Placebo

United States
Judith Feinberg

Unknown

Nasal Naloxone for Narcotic Overdose

Drug Overdose

United States
University of California, San Francisco
Johns Hopkins University

Terminated

The Effect of Chronic Pain on Delay Discounting in Methadone Patients

Opioid-use Disorder | Chronic Pain Syndrome

United States
Mitovie Pharma Ltd

Unknown

Naloxone Nasal Spray Pharmacokinetic Study

Opioid Overdose

Jordan
mads u werner
University of Kentucky

Completed

Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia During a Burn Injury (TCI-NX-BI)

Healthy Subjects

Denmark
S.L.A. Pharma AG

Completed

Naloxone SR Capsules in Patients With Opioid Induced Constipation

Chronic Pain | Opioid Induced Constipation

Germany, United Kingdom
mads u werner
University of Kentucky

Completed

Effect of High-dose Naloxone Following Third Molar Extraction (TME)

Pain, Acute | Healthy Subjects | Hyperalgesia | Sensitization, Central | Inflammations, Endodontic

Denmark
Pocket Naloxone Corp

Completed

Pharmacokinetic Evaluation of a New Naloxone Nasal Swab, Naloxone Nasal Spray, and Intramuscular Naloxone Injection in Healthy Volunteers

Opioid Overdose

Canada
Norwegian University of Science and Technology
St. Olavs Hospital; Smerud Medical Research International AS; A/S Den norske...

Completed

Bioavailability of Nasal Naloxone and Injected Naloxone Compared (OPI-15-002)

Drug Overdose

Norway
University of Washington
U.S. National Science Foundation

Completed

Naloxone Auto-injection in Healthy Volunteers

Overdose Antidote

United States
INSYS Therapeutics Inc

Completed

A Study to Compare Bioavailability of Naloxone Nasal Spray, Naloxone Hydrochloride (HCl) Intravenous (IV) and Intramuscular Injection (IM) in Healthy Volunteers

Healthy Volunteer

United States
Medical University of Vienna

Completed

Oral Oxycodone After Major Cardiac Surgery

Heart; Dysfunction Postoperative, Cardiac Surgery

Austria
Centre for Addiction and Mental Health
Academic Health Science Centres

Completed

Feasibility Study of Oral Naloxone for Treatment of Methadone-induced Constipation

Constipation

Canada
INSYS Therapeutics Inc

Completed

A Study to Compare Bioavailability of Naloxone Nasal Spray and Naloxone Hydrochloride (HCl) Intramuscular Injection (IM) in Healthy Volunteers

Healthy Volunteer

United States
Norwegian University of Science and Technology
St. Olavs Hospital

Completed

Pharmacokinetics and Pharmacodynamics of a New Formulation of Nasal Naloxone for Prehospital Use (OPI-14-001)

Drug Overdose

Norway
Norwegian University of Science and Technology
St. Olavs Hospital; University of Iceland

Completed

A Pilot Study of the Bioavailability of Nasal Naloxone

Drug Overdose

Norway
University of Washington

Unknown

Subjective Analgesic Effects of Naloxone and Virtual Reality (Narcan)

Pain

United States
Duke University
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Completed

Buprenorphine Physician-Pharmacist Collaboration in the Management of Patients With Opioid Use Disorder: CTN 0075 (Pharm-OUD-Care)

Opioid Use Disorder

United States
Kasr El Aini Hospital
Mansoura University

Completed

Influence Of Low Dose Intrathecal Naloxone On Bupivacaine - Fentanyl Spinal Anaesthesia For Lower Limb Orthopedic Surgery In Elderly Patients

Elderly | Anesthesia, Spinal

Egypt
New York State Psychiatric Institute
Schering-Plough

Completed

Abuse Liability of Suboxone Versus Subutex

Opioid-related Disorders

United States
Parc de Salut Mar
Food and Drug Administration (FDA)

Recruiting

Pharmacokinetics of Intravenous and Intranasal Formulations of Naloxone in Healthy Volunteers.

Healthy

Spain
University of Minnesota

Completed

Naloxone, Hypoglycemia and Exercise

Diabetes Mellitus, Type 1

United States
Kaiser Permanente
National Institute on Drug Abuse (NIDA); Denver Health and Hospital Authority

Completed

Impact of Direct Outreach to Expand Access to Naloxone in the Context of Standing Orders

Risk Behavior | Opioid Abuse | Overdose

United States
Norwegian University of Science and Technology
Oslo University Hospital; St. Olavs Hospital

Completed

Naloxone Nasal Spray Compared With Naloxone Injection for Opioid Overdoses Outside the Hospital (NINA-1)

Overdose | Drug Abuse

Norway
Emergent BioSolutions

Completed

Pharmacokinetics (PK) and Safety of Multiple Doses of Intranasal Naloxone in Healthy Adults

Opioid Overdose

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Buprenorphine Maintenance vs. Detoxification in Prescription Opioid Dependence

Opiate Dependence

United States
State University of New York - Upstate Medical...
Binghamton University

Completed

A Usability Assessment of Naloxone Administration by Untrained Community Members

Harm Reduction | Opioid-use Disorder | Naloxone

United States
Bicycle Health

Enrolling by invitation

Novel Induction to Buprenorphine/Naloxone

Opioid Use Disorder | Opioid Dependence | Opioid Use | Opioid Abuse | Opioid Misuse

United States
National Institute on Drug Abuse (NIDA)
Johns Hopkins University

Terminated

Abuse Potential of Buprenorphine/Naloxone

Opioid-Related Disorders

United States
National Institute on Drug Abuse (NIDA)

Completed

Buprenorphine Combination Tablet Feasibility - 1

Opioid-Related Disorders

United States
INSYS Therapeutics Inc

Completed

Study of Buprenorphine-Naloxone Sublingual Spray and Suboxone® Sublingual Film in Healthy Volunteers

Opiate Dependence

United States
National Institute on Drug Abuse (NIDA)
New York MDRU

Completed

Buprenorphine and Naloxone for the Treatment of Opiate Dependence - 1

Substance-Related Disorders | Heroin Dependence

United States
National Institute on Drug Abuse (NIDA)

Completed

Buprenorphine/Naloxone for Treatment of Opiate Dependence - 9

Opioid-Related Disorders

United States
University of Pennsylvania

Completed

Buprenorphine/Naloxone - Facilitated Rehabilitation for Opioid Dependent Adolescents - 1

Opioid-Related Disorders

United States
University of Maryland, Baltimore

Recruiting

Neural Mechanisms of Immersive Virtual Reality in Chronic Pain

Pain | Virtual Reality | Temporomandibular Disorder | Placebo

United States
Dartmouth-Hitchcock Medical Center

Completed

Role of Endorphins in the Perception of Dyspnea in Patients With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United States
Massachusetts General Hospital

Not yet recruiting

Buprenorphine/Naloxone Micro-Dosing for Postoperative Pain Management in Opioid-Tolerant Patients

Post-operative Pain

United States

Search clinical trials for: Naloxone hydrochloride

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