Search clinical trials for: Nitisinone (NTBC)

Total 41 results

National Human Genome Research Institute (NHGRI)

Completed

Long-Term Study of Nitisinone to Treat Alkaptonuria

Alkaptonuria

United States
University of Florida

Completed

Prevention of Dichloroacetate Toxicity

Chronic Disease | Acidosis, Lactic

United States
University of California, San Diego

Completed

Nitisinone (NTBC) In Different Age Groups Of Patients With Alkaptonuria

Alkaptonuria

United States
University of Washington

Completed

Study of NTBC for Tyrosinemia I

Tyrosinemia I

United States, Canada
Swedish Orphan Biovitrum

Completed

Bioequivalence of Orfadin Suspension Compared to Orfadin Capsules, and the Effect of Food on the Bioavailability of the Suspension

Healthy Volunteers

Netherlands
Cycle Pharmaceuticals Ltd.
Parexel

Completed

Bioequivalence Study of Two Oral Nitisinone Formulations to Treat Hereditary Tyrosinemia (HT-1)

Hereditary Tyrosinemia, Type I

South Africa
Swedish Orphan Biovitrum

Completed

Bioequivalence of Orfadin 20 mg Compared to Orfadin 10 mg Capsules.

Healthy

Netherlands
National Center for Research Resources (NCRR)
University of Michigan

Completed

Phase II Study of the Enzyme Inhibitor NTBC for Tyrosinemia Type I

Tyrosinemia, Type I
Cycle Pharmaceuticals Ltd.
Parexel

Completed

Bioequivalence Study of Two Nitisinone Formulations Compared to Orfadin

Hereditary Tyrosinemia, Type I

South Africa
Cycle Pharmaceuticals Ltd.
Parexel

Completed

Bioavailability Food-Effect Study of an Oral Nitisinone Formulation to Treat Hereditary Tyrosinemia (HT-1)

Hereditary Tyrosinemia, Type I

South Africa
Swedish Orphan Biovitrum

Completed

Taste and Palatability of Orfadin Suspension

Hereditary Tyrosinemia, Type I

Germany, United Kingdom, France
Swedish Orphan Biovitrum

Completed

Long Term Safety Study of Orfadin Treatment in HT-1 Patients in Standard Clinical Care (OPAL)

Hereditary Tyrosinemia, Type I

Belgium, Denmark, France, Germany, Austria, Czechia, Finland, Hungary, Ireland, Italy, Netherlands, Norway, Poland, Portugal, Spain, Sweden, United Kingdom
National Eye Institute (NEI)
National Human Genome Research Institute (NHGRI)

Completed

Nitisinone for Type 1B Oculocutaneous Albinism

Albinism | Vision Loss

United States
University of Liverpool

Unknown

Suitability of Nitisinone in Alkaptonuria 2 (SONIA 2)

Alkaptonuria

United Kingdom
Sutphin Drugs

Unknown

Bio Equivalency 20 Mgm Orfadin and 20 Mgm of Nitisonine (Orfadin)

Hereditary Tyrosinemia, Type I

India
Swedish Orphan Biovitrum

Completed

Efficacy and Safety of Once Daily Dosing Compared to Twice Daily Dosing of Nitisinone in HT-1 (HT-1)

Hereditary Tyrosinemia, Type I

Belgium, Denmark, France, Germany, Sweden
Brno University Hospital

Unknown

Early Identification of Sepsis in Children

Sepsis | Shock, Septic | SIRS | Sepsis, Severe

Czechia
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Safety of Recombinant HIV Vaccines in HIV Infected Young Adults on Stable Therapy

HIV Infections

United States, Puerto Rico
Swedish Orphan Biovitrum

Recruiting

A Non-interventional, Post-Marketing Study to Describe Outcome of Nitisinone Treatment in HT-1 Patients

Hereditary Tyrosinemia, Type I

China
University of Liverpool
Liverpool University Hospitals NHS Foundation Trust

Completed

Dose Response Study of Nitisinone in Alkaptonuria (SONIA1)

Alkaptonuria

United Kingdom
University of Thessaly

Completed

Metabolic Cost of Medicine Ball Training (MΒT-UTH)

Body Composition | Physical Fitness | Energy Expenditure | Resting Metabolic Rate

Greece
National Institute of Allergy and Infectious Diseases...

Completed

Determining an Effective Site (Groin Versus Arm) for Giving HIV Vaccines

HIV Infections

United States
University of Surrey

Completed

The Effect of New Zealand Blackcurrant (NZBC) Supplementation on Recovery Following Strenuous Exercise (CurraNZ_MD)

Muscle Damage

United Kingdom
Swedish Orphan Biovitrum
Parexel

Completed

A Study to Investigate the Potential Influence of Nitisinone on the Metabolism and the Transport of Other Drugs in Healthy Volunteers

Drug Drug Interaction

Germany
National Institute of Allergy and Infectious Diseases...

Completed

Safety of and Immune Response to Two HIV Vaccine Formulations (rMVA-HIV and rFPV-HIV) Alone or in Combination in HIV Uninfected Adults

HIV Infections

United States, Brazil
Neurotrigger Ltd

Recruiting

Evaluate the Usability of the Neuro-trigger Artificial Eye Blinking Stimulation Device in Patients With Paralysis of the Facial Nerve. (paralysis)

Paralysis | Paralysis; Eye | Paralysis; Bell

Israel
Centre Hospitalier Universitaire Vaudois
McGill University; Université du Québec à Trois-Rivières; University of Applied...

Unknown

A Team-Based Care for Hypertension Management (TBC-HTA) (TBC-HTA)

Hypertension

Switzerland
International AIDS Vaccine Initiative

Completed

Safety and Immunogenicity of TBC-M4, a MVA HIV Vaccine Alone or in a Prime-Boost Regimen With ADVAX DNA HIV Vaccine

HIV Infections

United Kingdom
Acclarent

Completed

Study of Safety and Efficacy for the Eustachian Tube Balloon Catheter (ELLIOTT)

Eustachian Tube Dysfunction

United States
Uro-Research, LLC

Unknown

Tissue Bonding Cystostomy(TBC) (TBC)

Urinary Incontinence | Spinal Cord Injury (SCI) | Chronic Urinary Retention
National Institute of Allergy and Infectious Diseases...

Completed

Phase I/II Trial of Modified Vaccinia Virus Ankara (MVA) Vaccine Against Smallpox

Healthy

United States
National Institute of Allergy and Infectious Diseases...

Completed

Phase I Trial of Smallpox Vaccine

Healthy

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Multicenter, Randomized, Placebo-Controlled, Double-Blind Trial to Evaluate the Safety and Immunogenicity of the Therion Recombinant Vaccinia-HIV-1 IIIB ENV/GAG/POL Vaccine (TCB-3B) and MN RGP 120/HIV-1 In Alum.

HIV Infections

United States
Sheba Medical Center

Unknown

Evaluating the Physiological Strain Induced by a BC Membrane Protective Garment Under Exercise-heat Stress Compared to a Protective Coverall

Physiological Stress

Israel
University of Arizona

Completed

Fall Prevention in Older Adults Study

Accidental Fall | Postural Balance

United States
Gulf Medical University
Srinivas University

Completed

Water Versus Land Based Perturbation Exercises in Elderly Participants With Back Pain

Back Pain | Back Pain Lower Back Chronic | Back Pain With Radiation | Back Pain Without Radiation

United Arab Emirates
National Institute of Allergy and Infectious Diseases...

Completed

A Multicenter, Randomized, Placebo-Controlled, Double-Blind Trial to Evaluate the Safety and Immunogenicity of a Recombinant Vaccinia-HIV-1 IIIB Env/Gag/Pol Vaccine (TBC-3B)

HIV Infections

United States
NanoSHIFT LLC

Terminated

Safety and Efficacy Study of NTC-510 to Treat Pain Following Dental Surgery of Third Molars

Dental Pain

United States
Cancer Institute and Hospital, Chinese Academy...
Beijing Huanxing Cancer Hospital; Cancer Hospital, Chinese Academy of Medical...

Recruiting

Adopting the MRD Strategy to Optimize Post-operation Adjuvant Therapies for Early Stage Breast Cancer (AMENDER)

Early-stage Breast Cancer

China
University of Birmingham
Regeneron Pharmaceuticals; Cancer Research UK; Fight Kids Cancer; ADC Therapeutics...

Not yet recruiting

A Global Study of Novel Agents in Paediatric and Adolescent Relapsed and Refractory B-cell Non-Hodgkin Lymphoma (Glo-BNHL)

B-cell Non Hodgkin Lymphoma
Baylor Research Institute

Completed

Safety Study Of Chemotherapy Combined With Dendritic Cell Vaccine to Treat Breast Cancer

Breast Cancer

United States

Search clinical trials for: Nitisinone (NTBC)

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