Search clinical trials for: nucleoside analogues

Total 400 results

Mahidol University

Completed

Steatohepatitis in Chronic Hepatitis B

Fatty Liver | Chronic Hepatitis b

Thailand
King Abdullah International Medical Research Center
Hoffmann-La Roche

Unknown

To Study the Effect of Adding on Pegylated Interferon (PEG-INF) Therapy for Patients Diagnosed With Chronic Hepatitis B (RC14/055)

Hepatitis B

Saudi Arabia
F-star Therapeutics, Inc.
PRA Health Sciences

Terminated

Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic, Hepatitis B e Antigen-negative Subjects Infected With HBV Virus and Receiving or Stopping Treatment With a NUC Inhibitor

Hepatitis B | Hepatitis B, Chronic | HBV

Canada, United Kingdom
St Vincent's Hospital Melbourne
National Health and Medical Research Council, Australia

Unknown

Determinants of Virological Response After Discontinuation of Nucleoside Analogue Therapy in Hepatitis B Patients (STOP)

Chronic Hepatitis B.

Australia
University of Exeter

Completed

Dietary Nucleotides and Ribose on Muscle Fuel Utilisation (FUN)

Healthy

United Kingdom
Gilead Sciences

Completed

Registry Study for Patients With Chronic HBV Receiving Nucleotide Therapy

Hepatitis B

United States, Canada
Third Affiliated Hospital, Sun Yat-Sen University
Peking University; First People's Hospital of Foshan; Shenzhen Third People's...

Unknown

The Optimizing Treatment of PegIFN Alfa in HBeAg-negative CHB Patients With Low Level HBsAg

Chronic Hepatitis B

China
Northwestern University
Abbott

Completed

SNAP: Switching Nucleoside Analogues Protocol - Lipoatrophy and Mitochondrial Function

HIV Infection

United States
Danish HIV Research Group
Odense University Hospital; Aarhus University Hospital; Rigshospitalet, Denmark; Hvidovre University Hospital and other collaborators

Unknown

Comparing a Nucleoside-Analogue-Sparing Regimen and a Protease-Inhibitor-Sparing Regimen in HIV Infected Patients

HIV-Associated Lipodystrophy Syndrome

Denmark
Beijing Ditan Hospital

Unknown

Cohort Study of Clinical Outcomes in Chronic HBV Infection Patients With Low HBsAg Under Unplanned Intervention

Chronic Hepatitis B Infection

China
Wen-hong Zhang
The First Affiliated Hospital with Nanjing Medical University; The First Affiliated... and other collaborators

Not yet recruiting

Predictive Value of HBV pgRNA on Long-term Outcomes in Hepatitis B Patients Treated With Antiviral Therapy

HCC | HBV

China
Beijing Ditan Hospital

Unknown

A Cohort Study on Long-term Clinical Outcomes of Antiviral Therapy in Patients With Chronic Hepatitis B and Cirrhosis

Chronic Hepatitis b

China
The University of Hong Kong

Active, not recruiting

Stopping Antiviral Treatment in Chronic Hepatitis B

Chronic Hepatitis b

Hong Kong
Qilu Hospital of Shandong University

Recruiting

Development and Validation of Models to Predict Functional Cure in Patients With CHB After Peg-IFN Based Therapy

Hepatitis B, Chronic

China
Shanghai Pudong Hospital

Not yet recruiting

Plasma Purification and Chronic Hepatitis B

Chronic Hepatitis b
Sun Yat-sen University

Unknown

Early Response to Interferon Combined Short-Term Nucleoside Analogue Therapy in HBeAg(+) Chronic Hepatitis B

Hepatitis B, Chronic

China
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

Peginterferon Treatment Study for Inactive Chronic Hepatitis B Patients

Hepatitis B, Chronic

China
Qilu Hospital of Shandong University

Recruiting

A Retrospective Observational Study on the Effects of Prebiotics on HBsAg Clearance

Chronic Hepatitis B

China
Sun Yat-sen University

Recruiting

Combination Treatment of NAs and Peg IFN α-2b for Hepatitis B Related, Compensatory Cirrhosis Patients

Cirrhosis of Liver Due to Hepatitis B (Disorder)

China
Beijing Ditan Hospital

Recruiting

Study of COVID-19 Infection and Its Clinical Prognosis in Chronic Hepatitis B Patients With Antiviral Therapy

Chronic Hepatitis B | COVID-19 Infection

China
SYZ Cell Therapy Co..
Sun Yat-sen University; Fujian Cancer Hospital; Beijing 302 Hospital; Nanfang Hospital... and other collaborators

Suspended

Multiple Antigen Specific Cell Therapy (MASCT) for Hepatocellular Carcinoma(HCC) Patients After Radical Resection or Radio Frequency Ablation(RFA). (HCC DC CTL)

Hepatocellular Carcinoma

China
Sun Yat-sen University
First People's Hospital of Foshan; Eighth Affiliated Hospital, Sun Yat-sen...

Recruiting

To Optimize the Therapeutic Pathway of Peginterferon Treatment in Patients With CHB Based on IFNA2p.Ala120Thr /ISGs. (IFNA2/ISGs)

Hepatitis B

China
Roxane Laboratories

Completed

Bioequivalency Study of Torsemide Tablets Under Fasting Conditions

Edema

United States
Henlix, Inc

Unknown

Evaluate the Efficacy and Safety of HLX10 in Chronic Hepatitis B Patients

Hepatitis B, Chronic

Taiwan
NuCana plc

Recruiting

A Safety, Pharmacokinetic and Clinical Activity Study of NUC-7738 in Patients With Advanced Solid Tumours and Lymphoma

Lymphoma | Solid Tumor | Advanced Cancer

United Kingdom
University of Exeter

Completed

High Nucleotide Meal Consumption in Uric Acid and Metabolic Health (TIDE)

Healthy

United Kingdom
Anhui Medical University
First Affiliated Hospital Bengbu Medical College; The Second Hospital of Anhui... and other collaborators

Recruiting

Efficacy of NA Combined With PEG-IFN-α2b in the Continuous Versus Pulsed Treatment of Patients With Chronic Hepatitis B (EPCP)

Hepatitis B, Chronic

China
Kirby Institute
Merck Sharp & Dohme LLC; amfAR, The Foundation for AIDS Research; Abbott

Completed

A Trial of 2 Options for Second Line Combination Antiretroviral Therapy Following Virological Failure of a Standard Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI)+2N(t)RTI First Line Regimen (SECOND-LINE)

HIV Infections

Taiwan, Australia, Argentina, Singapore, India, France, South Africa, Chile, Germany, Hong Kong, Ireland, Malaysia, Mexico, New Zealand, Nigeria, Peru, United Kingdom
Assiut University

Unknown

Nucleotide Protein -3 in Epileptic Children

Epilepsy in Children
Huahui Health

Active, not recruiting

A Study to Evaluate the Antiviral Activity and Safety of HH-003 in Chronic Hepatitis B Subjects With Low-level Viremia

Chronic HBV Infection

China
University Hospital, Basel, Switzerland

Completed

Whole Genome Single Nucleotide Polymorphisms in Elderly Patients With Postoperative Cognitive Dysfunction (GenPOCD)

Postoperative Cognitive Dysfunction

Switzerland
Array BioPharma

Completed

A Study of ARRY-334543 and Gemcitabine in Patients With Advanced Cancer and Pancreatic Cancer

Pancreatic Cancer | Advanced Cancer

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Two Rebeccamycin Analogue Regimens in Treating Patients With Advanced or Recurrent Non-small Cell Lung Cancer

Lung Cancer

United States
Medical University of Graz

Active, not recruiting

Breast Cancer Liquid Biopsy Stratification (BALIBISTRA)

Breast Cancer

Austria
University of Alabama at Birmingham

Completed

TLR4 Polymorphisms and Risk of Skin Cancer

Skin Cancer

United States
University of Exeter

Completed

Chronic Mycoprotein Consumption and Nucleotide Content in Metabolic Health (MYTH)

Healthy
Groupe Hospitalier Paris Saint Joseph

Recruiting

Interest of GLP1 Analogues in Overweight Type 2 Diabetic Patients With Chronic Inflammatory Bowel Disease (DiagMICI)

Diabetes Mellitus, Type 2 | Inflammatory Bowel Diseases

France
Ipsen

Completed

To Evaluate the Criteria for Renewal of Luteinizing Hormone-Releasing Hormone (LHRH) Analogue Treatment in Prostate Cancer Patients (ANAREN)

Prostate Cancer

Spain
National Cancer Institute (NCI)

Terminated

Rebeccamycin Analog as Second-Line Therapy in Treating Patients With Limited-Stage or Extensive-Stage Small Cell Lung Cancer That Relapsed After Previous First-Line Chemotherapy

Extensive Stage Small Cell Lung Cancer | Recurrent Small Cell Lung Cancer | Limited Stage Small Cell Lung Cancer

United States
University of Aarhus
Aarhus University Hospital; Velux Fonden

Active, not recruiting

The ProCaRis Study: Prostate Cancer Risk Assessment in General Practice (ProCaRis)

Prostate Cancer

Denmark
Nantes University Hospital

Completed

QDISS Stud: QD Isentress as Switch Strategy in Virologically Suppressed HIV-1 Infected-Patient (QDISS)

Virus-HIV

France
Peking University

Completed

Targeting Aging and Promoting Longevity With Exogenous Nucleotides (TALENTs)

Aging

China
Soroka University Medical Center
Materna Laboratories

Completed

Clinical Effects of a Nucleotides-Supplemented Infant Formula

Nutritional Requirements

Israel
HaEmek Medical Center, Israel

Completed

The Occurrence of Single Nucleotide Polymorphism Among Women Who Experienced Obstetric Anal Sphincter Injury

Delivery, Obstetric

Israel
University of Athens
Hellenic Sepsis Study Group

Completed

Personalized Needs in Clostridium Difficile Infections (SPECIFY)

Biologic Markers | Clinical Markers

Greece
Guy's and St Thomas' NHS Foundation Trust
Volition Diagnostics UK Ltd

Recruiting

ObsErvational Study of the Practical Cinical UTility of the NuQ.® H3.1 Nucleosome Levels in Adult Patients With Sepsis to Facilitate Early Diagnosis and Prognostication. (EPICETUS) (EPICETUS)

Sepsis

United Kingdom
Enyo Pharma
Parexel; Novotech (Australia) Pty Limited; Synteract, Inc.; Eurofins

Terminated

Study of EYP001a to Assess Its Safety and Anti-viral Effect in CHB Patients in Combination With NA (ETV or TD)

Hepatitis B, Chronic

Australia, Hong Kong, Korea, Republic of, Poland
Hospices Civils de Lyon

Unknown

Constitutional Genetics in Follicular Lymphoma (CONPIL)

Follicular Lymphoma | Genetic Predisposition to Disease

France
Nicola Frei

Not yet recruiting

Evaluation of Post-ERCP Pain as a Predictor for Post-ERCP Pancreatitis (PEP-PREPARE)

Post-ERCP Acute Pancreatitis

Switzerland
University Magna Graecia

Completed

CA 125 and VAS Pain Score Changes to Diagnose Endometriosis

Endometriosis | Pelvic Pain

Italy

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