Search clinical trials for: OBI-999

Total 3115 results

OBI Pharma, Inc

Terminated

Phase 1/2 Study of OBI-999 in Patients With Advanced Solid Tumors

Locally Advanced Solid Tumor

United States
Palobiofarma SL
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Terminated

Study to Assess the Safety, Tolerability and Pharmacokinetic Profile of PBF-999 "After Multiple Oral Doses" in Healthy Volunteers

Huntington Disease

Spain
Palobiofarma SL
Vall d'Hebron institute of oncology (VHIO), Catalan institute of oncology...

Completed

Study of PBF-999 in Solid Tumour Advanced Cancer

Cancer

Spain
Fundació Institut de Recerca de l'Hospital de la...
Palo Biofarma, S.L

Completed

Study To Assess the Safety and Tolerability of Single Ascending Oral Doses of PBF-999 in Healthy Young Male Volunteers

Huntington's Disease

Spain
Oncology Institute of Vojvodina

Recruiting

Ultra-hypofractionated for Whole Breast Irradiation (WBI) Compared to Partial Breast Irradiation (PBI)

Breast Cancer Female

Serbia
California State University, Long Beach

Completed

Active Moms Project: Physical Activity Intervention for Low-Income Mothers

Physical Inactivity
Ontario Clinical Oncology Group (OCOG)

Recruiting

A Randomized Trial of Five Fraction Partial Breast Irradiation

Breast Neoplasm Female | Radiotherapy | Cosmetic Outcome

Canada
OBI Pharma, Inc

Completed

Trial of Active Immunotherapy With OBI-833 (Globo H-CRM197) in Advanced/Metastatic Gastric, Lung, Colorectal or Breast Cancer Subjects

Metastatic Colorectal Cancer | Metastatic Lung Cancer | Metastatic Breast Cancer | Metastatic Gastric Cancer

Taiwan
Beijing Shenogen Biomedical Co., Ltd
The First Affiliated Hospital with Nanjing Medical University; Guilin Medical... and other collaborators

Unknown

The Phase III Study of Icaritin Versus HUACHANSU PIAN in Hepatocellular Carcinoma Subjects

Advanced HBV-Related Hepatocellular Carcinoma (HCC)

China
Memorial Sloan Kettering Cancer Center
BMS Foundation

Recruiting

Study of Peripheral Arterial Disease (PAD) in People With Cancer Who Will Be Having Surgery

Peripheral Arterial Disease (PAD) in Cancer Patients

United States
M.D. Anderson Cancer Center

Active, not recruiting

Tc99m Sestamibi Molecular Breast Imaging

Breast Cancer

United States
Medtronic Endovascular

Terminated

FlowMet-R Blood Flow Measurement for the Diagnosis of Peripheral Artery Disease and Critical Limb Ischemia

Peripheral Artery Disease

United States
The University of Texas at San Antonio
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University... and other collaborators

Completed

Míranos! Program, a Preschool Obesity Prevention RCT

Obesity | Physical Activity | Health Knowledge, Attitudes, Practice | Healthy Eating | Gross Motor Development

United States
Takeda

Recruiting

A Study About Fazirsiran in People With and Without Liver Problems

Hepatic Impairment

Hungary, Slovakia
T3D Therapeutics, Inc.
National Institute on Aging (NIA); Alzheimer's Association; Clinilabs, Inc.

Completed

Clinical Study Evaluating Efficacy and Safety of T3D-959 in Mild-to-moderate AD Subjects

Alzheimer Disease

United States
National Taiwan University Hospital

Recruiting

To Evaluate OBI-833/OBI-821 in Patients With Locally Advanced, Globo H-Positive Esophageal Cancer for Recurrence

Esophageal Cancer

Taiwan
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

Study to Test AKR1C3-Activated Prodrug OBI-3424 (OBI-3424) in Patients With Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Refractory T Acute Lymphoblastic Leukemia | Recurrent T Acute Lymphoblastic Leukemia

United States
OBI Pharma, Inc

Terminated

A Phase I/II Study of OBI-3424 in Subjects With Advanced Solid Tumors

Pancreatic Adenocarcinoma | Solid Tumor

United States
University of Michigan
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Health Explorer - Optimizing Alcohol Brief Interventions

Alcohol Abuse

United States
University Hospital, Tours

Terminated

Quantification of Dopamine Active Transporter (DAT) in Humans: Validation of a New Radiophamaceutical, the [18F] LBT-999 (LBT 999)

Idiopathic Parkinson Disease

France
Proactina S.A.
Pharmathen S.A.; ConsulTech GmbH; pharmtrace

Completed

Technical Performance Assessment of Tc-99m Tetrofosmin for Differentiation of Recurrence vs Radiation Necrosis in Patients With Glioma

Glioma (Diagnosis)

Hungary, France
Takeda

Enrolling by invitation

An Extension Study to Learn About the Long-Term Safety of Fazirsiran and if Fazirsiran Can Help People With Alpha-1 Antitrypsin Liver Disease

Alpha1-Antitrypsin Deficiency

United Kingdom, Germany, United States, Austria, Portugal
Takeda

Recruiting

Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)

Alpha1-Antitrypsin Deficiency

United States
Takeda

Completed

Study to Evaluate Absorption, Metabolism, and Excretion, of TAK-994 in 6 Healthy Male Adults

Healthy Volunteers

United States
NHS Greater Glasgow and Clyde
University of Glasgow

Unknown

Violence Brief Intervention Pilot v1.1

Alcohol Consumption | Violence | Facial Injuries

United Kingdom
M.D. Anderson Cancer Center

Completed

Setup Variation in the Supraclavicular Lymph Nodes Treatment in Breast Cancer Patients

Breast Cancer

United States
Arrowhead Pharmaceuticals

Active, not recruiting

Study of Fazirsiran (TAK-999, ARO-AAT) in Patients With Alpha-1 Antitrypsin Deficiency Associated Liver Disease (AATD)

Alpha 1-Antitrypsin Deficiency

Austria, Germany, United Kingdom
Takeda

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of TAK-994 in Healthy Participants

Healthy Participants

United States
Takeda
Takeda Development Center Americas, Inc.

Recruiting

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

Alpha1-Antitrypsin Deficiency

United States, Belgium, Switzerland, Canada, Australia, Germany, United Kingdom, Austria, France, Spain, Portugal, Italy, Poland
Mayo Clinic

Recruiting

Molecular Breast Imaging Guidance for Breast Biopsy for Patients With Breast Abnormalities

Breast Neoplasm

United States
AbbVie

Terminated

Study to Assess Adverse Events and How Oral ABBV-990 Moves Through the Body of Adult Healthy Participants

Healthy Volunteers

United States
St George's, University of London

Recruiting

Collection and Characterisation of Human Olfactory Ensheathing Cells

Spinal Cord Injury

United Kingdom
Mathew S. Maurer
National Heart, Lung, and Blood Institute (NHLBI); Yale University; Boston Medical... and other collaborators

Recruiting

Screening for Cardiac Amyloidosis With Nuclear Imaging for Minority Populations (SCAN-MP)

Amyloid Cardiomyopathy, Transthyretin-Related

United States
BTL Industries Ltd.

Completed

Effect of the BTL-899 Therapy for Non-invasive Lipolysis and Circumference Reduction of Abdomen

Improvement of Abdomen Appearance

Bulgaria
BTL Industries Ltd.

Completed

Effect of BTL-899 Device for Non-invasive Lipolysis on Human Upper Arms

Fat Burn

Bulgaria
AbbVie

Completed

A Study to Evaluate the Safety and Pharmacokinetics ABBV-399 in Japanese Participants With Solid Tumors

Advanced Solid Tumors Cancer

Japan
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

DCE-MRI and MBI in Assessing Tumor Response to Chemotherapy in Patients With Triple Negative Breast Cancer

Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma

United States
Oregon Health and Science University
Ionis Pharmaceuticals, Inc.

Recruiting

carDIo-ttranSSfOrm nucLEar Imaging Study (DISSOLvE)

Amyloidosis | Transthyretin Amyloid Cardiomyopathy

United States
Baxalta now part of Shire

Completed

Study of Modified Recombinant Factor VIII (OBI-1) in Subjects With Acquired Hemophilia A

Acquired Hemophilia A

United States, Canada, India, United Kingdom
Baxalta now part of Shire

Terminated

Study of Modified Recombinant Factor VIII (OBI-1) in Subjects With Congenital Hemophilia A

Hemophilia A

United States, South Africa, United Kingdom
University of Michigan
National Institute on Drug Abuse (NIDA)

Completed

Healthier You: Optimizing Screening, Brief Interventions, and Referral to Treatment (SBIRT) in the Emergency Department

Drug Abuse

United States
Arrowhead Pharmaceuticals

Completed

Safety, Tolerability and Pharmacodynamic Effect of Fazirsiran (TAK-999, ARO-AAT) (SEQUOIA)

Alpha 1-Antitrypsin Deficiency

United States, Spain, Netherlands, Germany, Italy, Portugal
Vertex Pharmaceuticals Incorporated

Recruiting

A Phase 1 Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics, of VX-993

Pain

United States
Vertex Pharmaceuticals Incorporated

Completed

A Phase 1 Dose Escalation Study of VX-993 in Healthy Participants

Pain

United Kingdom
Takeda

Terminated

A Study of TAK-994 in Adults With Type 1 and Type 2 Narcolepsy

Narcolepsy Type 1 (NT1) | Narcolepsy Type 2 (NT2)

China, United States, Korea, Republic of, France, Italy, Finland, Spain, Czechia, Canada, Japan, Hungary, Netherlands
BTL Industries Ltd.

Completed

High-Intensity Focused Electromagnetic Procedure and Radiofrequency for Toning of Buttocks

Muscle Tone

United States
Memorial Health University Medical Center

Unknown

Tilmanocept vs Sulfur Colloid in Sentinel Lymph Node Biopsy

Breast Cancer | Sentinel Lymph Node Biopsy

United States
Alkermes, Inc.
QPS Netherlands B.V.

Completed

Single and Multiple Ascending Dose and Food Effect PK Study in Healthy Adult and Elderly Subjects

Healthy

Netherlands
AbbVie

Active, not recruiting

A Study to Assess Disease Activity of Intravenously (IV) Infused Telisotuzumab Vedotin in Adult Participants With Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer

United States, Australia, France, Germany, Israel, Italy, Japan, Korea, Republic of, Taiwan
Washington University School of Medicine
Lloyd J. Old STAR Program

Terminated

Mapping Draining Lymph Nodes in CNS Malignancies

Central Nervous System Neoplasms | Central Nervous System Tumor

United States

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