Search clinical trials for: OPN-375

Total 8430 results

Optinose US Inc.

Recruiting

OPN-375 Efficacy and Safety in Adolescents With Bilateral Nasal Polyps

Bilateral Nasal Polyposis

United States
Optinose US Inc.

Completed

Study Evaluating the Efficacy and Safety of Intranasal Administration of OPN-375 in Subjects With Chronic Rhinosinusitis With or Without the Presence of Nasal Polyps

Chronic Rhinosinusitis

United States, United Kingdom, Bulgaria, Canada, Georgia, Poland, Russian Federation, Sweden
Optinose US Inc.

Completed

Study Evaluating the Efficacy and Safety of Intranasal Administration of OPN-375 in Subjects With Chronic Rhinosinusitis Without the Presence of Nasal Polyps

Chronic Rhinosinusitis

United States, Australia, Poland, New Zealand, Spain, Georgia, United Kingdom, Bulgaria, Czechia, Romania
Opsona Therapeutics Ltd.
M.D. Anderson Cancer Center; Montefiore Medical Center; New York Presbyterian... and other collaborators

Completed

A Phase I/II Study of OPN-305 in Second-line Lower Risk Myelodysplastic Syndrome

Myelodysplastic Syndrome

United States
Opsona Therapeutics Ltd.
M.D. Anderson Cancer Center; Montefiore Medical Center; New York Presbyterian... and other collaborators

Completed

Follow up Protocol to the Phase I/II Study of OPN-305 in Second-line or Third-line Lower Lower Risk Myelodysplastic Syndrome

Myelodysplastic Syndrome

United States
Opsona Therapeutics Ltd.

Completed

Placebo-Controlled Study to Evaluate the Safety and Efficacy of OPN-305 in Preventing Delayed Renal Graft Function

Delayed Graft Function

United States, Spain, Belgium, Switzerland, France, Germany, United Kingdom, Poland, Netherlands, Austria, Czech Republic
Otsuka Frankfurt Research Institute GmbH

Completed

Safety, Efficacy and Pharmacokinetics of OPC-67683 in Patients With Pulmonary Tuberculosis

Pulmonary Tuberculosis

South Africa
Neuramedy Co. Ltd.
Quotient Sciences

Not yet recruiting

Single and Multiple Ascending Dose Study to Assess Safety, Tolerability and Pharmacokinetics of NM-101

Parkinson Disease

United Kingdom
Syndax Pharmaceuticals
Merck Sharp & Dohme LLC

Completed

Ph1b/2 Dose-Escalation Study of Entinostat With Pembrolizumab in NSCLC With Expansion Cohorts in NSCLC, Melanoma, and Colorectal Cancer

Melanoma | Non-Small Cell Lung Cancer | Mismatch Repair-Proficient Colorectal Cancer

United States
Chong Kun Dang Pharmaceutical

Unknown

The Clinical Trial to Investigate the Pharmacokinetics and Safety/Tolerability of CKD-375

Type 2 Diabetes Mellitus
Chong Kun Dang Pharmaceutical

Unknown

A Clinical Study to Evaluate the Pharmacokinetics, Safety and Tolerability of CKD-375

Type2 Diabetes Mellitus

Korea, Republic of
Guangdong Zhongsheng Pharmaceutical Co., Ltd.

Completed

Study in Chinese Healthy Adults to Evaluate the Safety, Tolerability and Pharmacokinetics on ZSP1601, and the Effect of Food on ZSP1601 Pharmacokinetics

Nonalcoholic Steatohepatitis (NASH)

China
Takeda

Completed

Efficacy of Ramelteon in Subjects With Chronic Insomnia

Sleep Initiation and Maintenance Disorders

United States
Takeda

Completed

The Exploratory Study to Investigate the Effect of Ramelteon for Insomnia Patients With Major Depressive Disorder by Using Actigraphy

Insomnia | Major Depressive Disorder

Japan
Takeda

Completed

Pharmacokinetic and Safety of Ramelteon Between Adolescents With Insomnia and Healthy Adults

Insomnia

United States
Takeda

Completed

Efficacy and Safety of Ramelteon in Subjects With Mild to Moderate Alzheimer's Disease

Chronic Insomnia

United States
Sohag University

Active, not recruiting

Clinical Outcomes of Post-placental Insertion of Cupper T380A and Multiload 375 Contraceptive Devices During Cesarean Section

IUD; Complications, Infection or Inflammation | IUD (Intrauterine Device) Malposition

Egypt
Northwestern University
Takeda

Terminated

Efficacy and Tolerability of Ramelteon in Patients With Rapid Eye Movement (REM) Behavior Disorder and Parkinsonism

Parkinsonism | REM Behavior Disorder

United States
Takeda

Completed

Long-Term Efficacy of Ramelteon on Endocrine Function in Adult Subjects With Chronic Insomnia

Insomnia

United States
Takeda

Completed

Long-Term Efficacy and Safety of Ramelteon in Adults With Chronic Insomnia.

Chronic Insomnia

United States, Australia, France, Germany, Belgium, Finland, Russian Federation, Italy, Czech Republic
Takeda

Completed

Subjective Efficacy of Ramelteon on Sleep in Adults With Chronic Insomnia.

Chronic Insomnia

United States
Takeda

Terminated

Efficacy of Ramelteon in Adults With Chronic Insomnia

Chronic Insomnia

United States
Takeda

Completed

Efficacy of Ramelteon on Speeding Up Sleep in Subjects With Delayed Sleep Phase Syndrome

Sleep Disorders, Circadian Rhythm

United States
Takeda

Completed

Safety and Efficacy of Ramelteon in Elderly Subjects With Chronic Insomnia

Chronic Insomnia

United States, Canada
Takeda

Completed

Efficacy of Ramelteon on Transient Insomnia in Healthy Adults

Transient Insomnia

United States
Takeda

Completed

Safety and Efficacy Study of Ramelteon in Subjects With Chronic Insomnia

Sleep Initiation and Maintenance Disorders
Takeda

Completed

Ramelteon in Adults With Chronic Insomnia

Chronic Insomnia

United States
Takeda

Completed

Study of Efficacy of Ramelteon in Adults With Chronic Insomnia

Chronic Insomnia

United States
Takeda

Completed

Safety and Efficacy of Ramelteon in Healthy Subjects

Sleep Disorder

United States
Takeda

Completed

Efficacy of Ramelteon on Insomnia Symptoms Associated With Jet Lag in Healthy Adult Volunteers

Circadian Dysregulation

United States
Apnimed

Completed

AD109 Dose Finding in Mild to Moderate OSA

Obstructive Sleep Apnea

United States
Takeda

Completed

Safety of Ramelteon in Subjects With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United States
Takeda

Completed

Safety of Ramelteon in Subjects With Mild to Moderate Obstructive Sleep Apnea

Sleep Apnea, Obstructive

United States
Optinose US Inc.

Completed

Efficacy and Safety Study of Intranasal Administration of 100, 200, and 400 μg of Fluticasone Propionate Using a Novel Bi-directional Device

Bilateral Nasal Polyposis

United States
Optinose US Inc.

Completed

12-Month OL Intranasal Fluticasone Propionate BID Using OptiNose Device

Nasal Polyps

United States
Optinose US Inc.

Completed

Study Evaluating the Efficacy and Safety of Intranasal Administration of 100, 200, and 400 μg of Fluticasone Propionate Twice a Day (BID) Using a Novel Bi Directional Device in Subjects With Bilateral Nasal Polyposis Followed by an 8-Week Open-Label Extension Phase to Assess Safety

Bilateral Nasal Polyposis

United States, Canada
Takeda

Completed

Safety of Ramelteon in Subjects With Mild to Moderate Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease | COPD

United States
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Aliskiren in Pediatric Hypertensive Patients 6-17 Years of Age

Hypertension

United States, Belgium, Hungary, Turkey, Guatemala, Slovakia, Germany, Puerto Rico, Poland
Syndax Pharmaceuticals
Merck Sharp & Dohme LLC

Completed

Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

Neoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms, Glandular and Epithelial | Digestive System Neoplasms | Endocrine Gland Neoplasms | Breast Diseases | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Respiratory Tract Neoplasms | Thoracic Neoplasms | Bronchial Neoplasms | Solid Tumors | Renal...

United States
Novartis Pharmaceuticals

Completed

Crossover Study to Evaluate the Efficacy, Safety and Tolerability of Different Doses of Indacaterol in Patients With Persistent Asthma (QAB149)

Asthma

United States
University of Alexandria

Not yet recruiting

Post-surgical Delirium in Patients Undergoing Open Heart Surgery.

Delirium | Open Heart Surgery

Egypt
Optinose US Inc.

Terminated

A Study to Evaluate Change in Viral Load After OPN-019 in Adults With COVID-19

Covid19

Mexico
Assiut University

Unknown

Markers of Vascular Calcification in Diabetic Nephropathy in Patients With Diabetic Nephropathy

Diabetic Nephropathies | Vascular Calcification

Egypt
Cytokinetics

Completed

A Study of CK-2017357 in Patients With Peripheral Artery Disease and Symptomatic Claudication

Intermittent Claudication | Peripheral Artery Disease

United States
Takeda

Completed

Safety and Efficacy of Ramelteon in Elderly Subjects With Chronic Insomnia.

Chronic Insomnia

United States
Takeda

Completed

Efficacy and Safety of Ramelteon on Chronic Insomnia

Chronic Insomnia
Hacettepe University

Not yet recruiting

Effect of Open Kinetic Chain Shoulder Exercises on Scapulothoracic Muscle Activity on Stable and Unstable Ground

Muscle Weakness | Exercise

Turkey
Indiana University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Terminated

Pediatric Robotic Versus Open Pyeloplasty

Pediatric Urology | Ureteropelvic Junction Obstruction

United States
Verrica Pharmaceuticals Inc.
Instat Clinical Research; HeartcoR Solutions; Myonex; Vial Health Technology, Inc

Recruiting

Open-Label Proof of Concept Study of VP-315 in Basal Cell Carcinoma

Carcinoma | Skin Cancer | Basal Cell Carcinoma | Cancer of the Skin, Basal Cell | Cancer of the Skin

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Safety and Efficacy of the Combination of the Antibody Pembrolizumab and Entinostat in Patients With Myelodysplastic Syndrome Who Are Not Responding to Hypomethylating Agents

Myelodysplastic Syndrome

United States

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