Search clinical trials for: OZ439 400mg API capsules

Total 149 results

Medicines for Malaria Venture

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of OZ439 in Healthy Male and Female Subjects

Healthy Volunteers | Malaria Falciparum | Malaria Vivax

United States
Medicines for Malaria Venture
Syneos Health; Nucleus Network Ltd

Completed

Study To Investigate The Relative Bioavailability of OZ439 Formulations In Healthy Volunteers

Healthy Volunteers

Australia
Shanghai Jiatan Pharmatech Co., Ltd

Completed

Sudapyridine (WX-081) in Healthy Volunteers

Healthy

China
Medicines for Malaria Venture
University of Cape Town

Terminated

Safety, Tolerability & Pharmacokinetics (PK) of Co-administered Single Doses of OZ439 and Mefloquine (MQ) in Healthy Volunteers

Malaria

South Africa
Chong Kun Dang Pharmaceutical

Completed

Study to Investigate the Effects of Food on the Pharmacokinetics/Pharmacodynamics of CKD-519

Healthy Volunteers

Korea, Republic of
University of California, Los Angeles

Completed

Therapeutic Response of Cannabidiol in Rheumatoid Arthritis

Rheumatoid Arthritis | Cannabis

United States
Aclaris Therapeutics, Inc.

Completed

ATI-501 Oral Suspension Compared to Placebo in Subjects With Alopecia Areata, Alopecia Universalis or Alopecia Totalis

Alopecia

United States
Cheng-Chung Wei
Golden Biotechnology Corporation

Unknown

A Randomized, Placebo-controlled Trial of Antroquinonol in Patients With Chronic Hepatitis B

Chronic Hepatitis B

Taiwan
Medicines for Malaria Venture
Cross Research S.A.

Completed

Safety Tolerability & Pharmacokinetics of Co-administered Single Doses of OZ439 & Piperaquine to Healthy Subjects

Healthy

Switzerland
Medicines for Malaria Venture
Quotient Clinical

Completed

Bioavailability Study of Oral OZ439 Prototype Formulations Administered With Piperaquine Phosphate (PQP)

Malaria

United Kingdom
Stiefel, a GSK Company
GlaxoSmithKline

Completed

A Study to Compare the Blood Levels of Albaconazole in Healthy Subjects Who Have Received a Single Dose of 400 mg Albaconazole as a Tablet Versus Albaconazole as a Capsule

Onychomycosis

United States
Guangzhou Yipinhong Pharmaceutical CO.,LTD

Completed

The Safety and Tolerability of Metacavir Enteric-coated Capsules in Healthy Adult Volunteers

Chronic Hepatitis B

China
Medicines for Malaria Venture
Richmond Pharmacology Limited

Completed

Healthy Volunteer Study of the Pharmacokinetics of Oral Piperaquine With OZ439 + TPGS Formulation in the Fasted State

Malaria

United Kingdom
Hyundai Pharmaceutical Co., LTD.

Completed

Compare Safety and Pharmacokinetic Properties of Surfolase Capsule(Acebrophylline 100mg) and Surfolase CR(200mg)

Healthy Male
University of South Florida
Edison Pharmaceuticals Inc

Completed

A Phase 2A Trial of EPI-743 for Patients With Parkinson's Disease

Parkinson's Disease

United States
DS Biopharma

Terminated

Efficacy and Safety of Orally Administered DS107 in Adult Patients With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

United States, Austria, Germany, Latvia, Poland
CTI BioPharma
SGS S.A.

Completed

Determine Pacritinib Pharmacokinetics in Impaired Hepatic Patients and Healthy Subjects

Myelofibrosis

Moldova, Republic of, Germany
Medicines for Malaria Venture

Completed

A Comparison of the Bioavailability of OZ439 When Delivered Directly to the Small Intestine, or Via the Oral Route

Healthy Volunteers

United Kingdom
Reata, a wholly owned subsidiary of Biogen

Completed

RTA 408 Capsules in Patients With Melanoma - REVEAL

Melanoma | Unresectable (Stage III) Melanoma | Metastatic (Stage IV) Melanoma

United States
Kwang Dong Pharmaceutical co., ltd.

Unknown

To Evaluate the Safety, Tolerability, PK, PK-PD Relation of KD101 in the Fed State in Obese or Overweight Subjects

Obesity

Korea, Republic of
Medicines for Malaria Venture

Completed

Phase II Efficacy Study of Artefenomel & Piperaquine in Adults & Children With P. Falciparum Malaria.

Uncomplicated Plasmodium Falciparum Malaria

Uganda, Benin, Burkina Faso, Congo, The Democratic Republic of the, Gabon, Mozambique, Vietnam
TaiGen Biotechnology Co., Ltd.

Completed

A Study Evaluating the Effect of a Single-dose Oral Administration of Nemonoxacin Capsule on QTc Intervals and Heart Rhythms of Healthy Subjects and the Influence of Food Intake on QTc Intervals and Pharmacokinetic Characteristics

Healthy Volunteers
MedDay Pharmaceuticals SA

Unknown

Effect of MD1003 in Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis (MS-ON)

Multiple Sclerosis

United Kingdom, France
SIGA Technologies
Biomedical Advanced Research and Development Authority

Withdrawn

A Phase 4, Observational Field Study to Evaluate TPOXX in Patients With Smallpox

Smallpox

United States
MedDay Pharmaceuticals SA

Unknown

Effect of MD1003 in Spinal Progressive Multiple Sclerosis (MS-SPI)

Multiple Sclerosis

France
Hanlim Pharm. Co., Ltd.

Completed

A Multicenter, Randomized, Double-blind, Parallel Group Study to Determine the Optimal Dose of HL301 After 7 Days Oral Administration in Acute Bronchitis or Acute Exacerbations of Chronic Bronchitis Patients (HL301: Mixed Extract of Rehmannia Glutinosa, Schisandra and so on) (HL301)

Acute Exacerbations of Chronic Bronchitis | Acute Bronchitis

Korea, Republic of
Al-Azhar University

Completed

Host Modulatory Effects of β-glucan on Localized Aggressive Periodontitis

Localized Aggressive Periodontitis
HK inno.N Corporation

Completed

Bioequivalence and Safety Study of IN-A012 and Akynzeo Capsules in Male and Female Healthy Korean Subjects

Healthy

Korea, Republic of
Khoo Teck Puat Hospital

Recruiting

Omega-3 Supplementation for LIver VolumE Reduction Study (OLIVER) Study (OLIVER)

Fatty Liver | Bariatric Surgery Candidate

Singapore
Imperial College Healthcare NHS Trust
National Institute for Health Research, United Kingdom

Completed

Effects of Oral Sodium Bicarbonate Supplementation in Haemodialysis Patients (BicHD) (BicHD)

End-stage Renal Disease

United Kingdom
University of Nottingham
University of Oxford; Nottingham University Hospitals NHS Trust; University of... and other collaborators

Completed

Helicobacter Eradication Aspirin Trial (HEAT)

Bacterial Infection Due to Helicobacter Pylori (H. Pylori) | Gastrointestinal Ulcer Haemorrhage

United Kingdom
Corcept Therapeutics

Completed

First-in-human Study in Healthy Subjects

Healthy

United Kingdom
Joe Fenn

Completed

Study to Evaluate Safety and Efficacy of PreCrea® on Subjects With Higher Than Normal Blood Sugar Levels (Precrea)

Hyperglycemia | Diabetes Mellitus | Metabolic Syndrome | Pre-Diabetes

India
Steven Moore
Racing the Planet

Recruiting

Effects of Riboflavin in Mitigating Muscle Soreness in Ultra-marathon Athletes

Muscle Soreness

United States
Texas Tech University Health Sciences Center

Completed

Pharmacokinetics of Decursin/Decursinol Angelate (CognIQTM)

Healthy

United States
Chung Shan Medical University
Golden Biotechnology Corporation

Terminated

A Phase II, Placebo-controlled Trial Evaluating the Efficacy of Antroquinonol in Patients With Atopic Dermatitis

Atopic Dermatitis

Taiwan
Ascentage Pharma Group Inc.
Suzhou Yasheng Pharmaceutical Co., Ltd.

Recruiting

APG-2449 in Patients With Advanced Solid Tumors

Esophageal Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Malignant Pleural Mesothelioma | Advanced Solid Cancer

China
Beta Pharma, Inc.

Completed

A Phase I Study to Determine the Effect of Food on the Pharmacokinetic Profile of BPI-7711

NSCLC

China
Vedic Lifesciences Pvt. Ltd.

Completed

Study to Evaluate Efficacy of EnXtra on Accuracy & Reaction Time, Perceived Alertness & Digital Fatigue for Video Gamers

Alert Fatigue, Health Personnel

India
Galapagos NV

Completed

Single and Multiple Dose Pharmacokinetics of GLPG0634 in Elderly Healthy Subjects

Healthy

Belgium
Instituto Mexicano del Seguro Social

Completed

Effect of the Use of Probiotic S. Boulardii on Acute Viral Inflammatory Diarrhea Diagnosed With Multiplex PCR.

Viral Diarrhea

Mexico
Medicines for Malaria Venture
Richmond Pharmacology Limited

Completed

Open Label Pharmacokinetic Study of OZ439 and Piperaquine on Administration of OZ439+TPGS Granules for Oral Suspension Alone or With Either Piperaquine Phosphate Tablets or Granules for Oral Solution in Healthy Volunteers

Malaria

United Kingdom
Chong Kun Dang Pharmaceutical

Completed

The Study to Evaluate Efficacy and Safety of Celecoxib Capsule in Hand Osteoarthritis Patients

Osteoarthritis Hand

Korea, Republic of
AstraZeneca
Parexel

Terminated

Evaluation of AZD8154 Concentrations in Blood

Asthma

Germany
Georgetown University

Unknown

Impact of Nilotinib on Safety, Tolerability, Pharmacokinetics and Biomarkers in Parkinson's Disease (PD Nilotinib)

Parkinson Disease | Parkinsons Disease With Dementia

United States
Northwestern University
University of Iowa; University of Rochester; Michael J. Fox Foundation for Parkinson...

Completed

Nilotinib in Parkinson's Disease (NILO-PD)

Parkinson Disease

United States
University of Oxford
Oxford University Hospitals NHS Trust

Unknown

The Oxford Marfan Trial

Marfan Syndrome

United Kingdom
Reckitt Benckiser Healthcare (UK) Limited
Premier Research Group plc

Completed

Ibuprofen Liquid Capsules 2 x 200 mg Efficacy and PK/PD Study in Surgical Removal of Impacted Third Molars

Stomatognathic Diseases | Tooth Diseases | Tooth, Impacted

United States
LEO Pharma

Completed

A Trial to Investigate the Safety, Tolerability, and Drug Levels in Blood After Single and Multiple Doses of LEO 32731 in Healthy People

Healthy

United Kingdom
Suzhou Zanrong Pharma Limited

Recruiting

Trial of ZN-A-1041 Enteric Capsules in Patients With HER2-Positive Advanced Solid Tumors

Advanced Solid Tumors | HER2-positive Breast Cancer

China

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