Search clinical trials for: Omeprazole

Total 817 results

Takeda
Richmond Pharmacology Limited

Completed

Safety, Tolerability, and Pharmacokinetics of TAK-438 in Healthy Western Male Subjects, Preliminary Food Effect Analysis, and an Ethnic Comparison With Japanese Subjects

Dose Finding Study
Lise Tarnow
Novo Nordisk A/S; Steno Diabetes Center Copenhagen; Chr Hansen; Statens Serum Institut

Completed

The Effect of Nexium and Probiotics on Insulin Secretion and Cardiovascular Risk Factors in Patients With Type 2 Diabetes (Nexium)

Type 2 Diabetes
AstraZeneca
UMC Utrecht

Completed

PPI Test in GP Patients

GERD

Netherlands
GlaxoSmithKline
Medicines for Malaria Venture

Completed

Efficacy and Safety Study of Tafenoquine (TQ) Co-administered With Dihydroartemisinin-piperaquine (DHA-PQP) for the Radical Cure of Plasmodium Vivax (P. Vivax) Malaria

Malaria, Vivax

Indonesia
Brigham and Women's Hospital

Completed

Oral OKT3 for the Treatment of Active Ulcerative Colitis

Ulcerative Colitis

United States
Royal Marsden NHS Foundation Trust

Unknown

IH636 Grape Seed Extract in Treating Hardening of Breast Tissue in Women Who Have Undergone Radiation Therapy for Early Breast Cancer

Breast Cancer | Radiation Fibrosis

United Kingdom
Eli Lilly and Company

Completed

Effects of Teriparatide in Postmenopausal Women With Osteoporosis

Postmenopausal Osteoporosis

United States
Bristol-Myers Squibb

Completed

A Study to Assess the Levels in Blood Plasma of BMS-986278 in Healthy Participants Following Administration of Tablets, With or Without Food, and in the Presence of an Antacid (Esomeprazole)

Healthy Participants

United States
Millennium Pharmaceuticals, Inc.

Completed

A Study to Assess the Relative Bioavailability, Effect of Food, and Gastric Potential Hydrogen (pH) Modification on the Pharmacokinetics (PK) of TAK-931 in Participants With Advanced Solid Tumors

Neoplasms, Advanced Solid

Netherlands
AstraZeneca

Completed

PPI Sequencing Study

Gastro-Oesophageal Reflux Disease

United Kingdom
Yooyoung Pharmaceutical Co., Ltd.

Completed

PK/PD Clinical Trial of YYD601 in Healthy Adult Male

GERD

Korea, Republic of
Otsuka Pharmaceutical Co., Ltd.

Completed

A Study to Investigate Pharmacodynamics and Pharmacokinetics of OPC-41061 in Patients With Hepatic Edema

Cirrhosis

Japan
Seoul National University Hospital

Completed

Study to Evaluate Effects of Food or Proton Pump Inhibitor on the Pharmacokinetics of Itraconazole in Healthy Volunteers

Achlorhydria

Korea, Republic of
EMS

Completed

Evaluation of Two Therapies for the Treatment of Osteoarticular Inflammation in Dyspeptic Patients

Dyspepsia | Acute and Chronic Inflammation

Brazil
Pamukkale University

Completed

A Comparison of Efficacy of Intravenous Esomeprazole and Ranitidine Treatment of Dyspeptic Pain

Dyspepsia

Turkey
National Cancer Institute (NCI)

Completed

Esomeprazole Magnesium With or Without Aspirin in Preventing Esophageal Cancer in Patients With Barrett Esophagus

Esophageal Cancer | Barrett Esophagus

United States
AstraZeneca

Completed

Comparative Efficacy & Safety Study of Esomeprazole Versus Placebo for the Prevention of Gastric and Duodenal Ulcers With NSAID

Osteoarthritis | Rheumatoid Arthritis | Lumbago | Gastric Ulcer | Duodenal Ulcer

Japan
Christiana Care Health Services

Active, not recruiting

Metformin and Esomeprazole in Preterm Pre-eclampsia

Pre-Eclampsia | Preeclampsia | Preterm | Preeclampsia Severe | Preeclampsia Second Trimester | Preeclampsia Complicating Childbirth | Preeclampsia Puerperium

United States
Eurofarma Laboratorios S.A.

Withdrawn

Study Comparing Esomeprazole Associated With Sodium Bicarbonate From Eurofarma and Esomeprazole in Treatment of Gastroesophageal Reflux Disease ESOBIC

Gastroesophageal Reflux Disease

Brazil
Radboud University Medical Center

Completed

Influence of Cola on the Absorption of the HCV Agent Velpatasvir in Combination With PPI Omeprazole. (COPA)

Hepatitis C | Swallowing Disorder

Netherlands
Icahn School of Medicine at Mount Sinai

Completed

High Dose Dual Therapy vs Clarithromycin Triple Therapy for Treatment Naive H Pylori Infection in an Urban Population

Helicobacter Pylori Infection

United States
AstraZeneca
Quintiles, Inc.

Completed

Effects of AZD1775 on the PK Substrates for CYP3A, CYP2C19, CYP1A2 and on QT Interval in Patients With Advanced Cancer

Solid Tumours

United States
SK Life Science, Inc.

Completed

Assess the Influence of Cenobamate on the PK of Cytochrome P450 (CYP) Probe Drugs as a Means of Predicting Drug-drug Interactions

Healthy

United States
POZEN

Completed

A Study to Evaluate Platlet Aggregation of Clopidogrel, EC Aspirin 81 mg, EC Omeprazole 40 mg Compare to PA32540

Platelet Aggregation

United States
AstraZeneca

Completed

AZD2066 Cocktail Study

Chronic Pain

United Kingdom
Pronova BioPharma

Completed

PRC-4016 (Icosabutate) Phase I Drug-drug Interaction Study

Healthy

United Kingdom
Shandong University
Zibo Central Hospital; Peking University Care Luzhong Hospital; Yuncheng Traditional... and other collaborators

Completed

Bismuth-containing Quadruple Therapy for Helicobacter Pylori First-line Treatment of Different Tetracycline Doses

Helicobacter Pylori Infection

China
National Taiwan University Hospital
Haemonetics Corporation

Unknown

Evaluation of Antiplatelet Drug Resistance in Taiwanese With VASP & Platelet Mapping ™ Assay

30 Healthy People

Taiwan
Odense University Hospital
Hospital of Southern Jutland

Not yet recruiting

Treatment of Gastroesophageal Reflux Disease in Infants

Infant, Newborn, Diseases | Gastroesophageal Reflux
Sanofi
Bristol-Myers Squibb

Completed

Interaction Study of Clopidogrel 600/150 mg Given Alone or Concomitantly With Omeprazole 80 mg in Healthy Subjects

Healthy

United States
Damascus Hospital
UNIPHARMA. Universal Pharmaceutical Industries; Ibn Alhaytham Pharma. Industries...

Unknown

Comparison Efficacy of 14-day Triple Therapy: Clarithromycin vs. Levofloxacin on Eradication of H. Pylori

Helicobacter Pylori Gastrointestinal Tract Infection

Syrian Arab Republic
Göteborg University

Completed

Preoperative Non-steroidal Anti-inflammatory Drugs(NSAID) to Colorectal Cancer Patients

Colorectal Cancer

Sweden
Pfizer

Completed

A Study to Evaluate the Effects of Food and Esomeprazole on the Pharmacokinetics of Crizotinib in a Coated Microsphere Formulation.

Healthy

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Evaluate the Effect of Multiple Doses of Esomeprazole on the Pharmacokinetics of Isavuconazole

Healthy Subjects | Pharmacokinetics of Isavuconazole

United States
Yooyoung Pharmaceutical Co., Ltd.

Completed

Clinical Trial to Assess the Efficacy and Safety of YYD601 in the Treatment of Esophageal Reflux Disease (ERD)

Erosive Esophagitis

Korea, Republic of
Synthetic Biologics Inc.

Completed

A Study Evaluating the Effect of Esomeprazole on SYN-004 Degradation of Ceftriaxone In Adults With an Ileostomy

Healthy Volunteers With Ileostomy

Canada
Hoffmann-La Roche

Completed

A Study Investigating the Effect of Food and Esomeprazole on the Single Oral Dose Pharmacokinetics of Alectinib (RO5424802) in Healthy Volunteers.

Healthy Volunteer

United States
University of Texas Southwestern Medical Center

Terminated

Pioglitazone as Second-Line in Patients With Metastatic Pancreatic Cancer After Treatment With Gemcitabine

Pancreatic Cancer

United States
Yanqing Li
The Affiliated Hospital of Qingdao University; The Second Affiliated Hospital... and other collaborators

Recruiting

Comparison of Two Dual Therapies in the First-line Treatment of Helicobacter Pylori Infection （SHARE2301）

Helicobacter Pylori Infection

China
AstraZeneca

Completed

Study Comparing a Fixed-Dose Capsule of Esomeprazole 40mg and LDA 325mg With Free Combination

Ulcers | Upper GI Symptoms
AstraZeneca

Completed

ASTERIX: Low Dose ASA and Nexium

Gastroesophageal Reflux

Bulgaria, Italy, South Africa, Spain, Hungary, Canada, Hong Kong, Greece, Germany, Australia, United Kingdom
Novartis Pharmaceuticals

Completed

Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid Tumors

Advanced Solid Tumors, Excluding Breast Cancer

United States
Daiichi Sankyo, Inc.
Medpace, Inc.

Completed

Drug-drug Interaction Study of Tivantinib (ARQ 197) With Omeprazole, S-warfarin, Caffeine, Midazolam, and Digoxin in Cancer Subjects

Solid Tumors

United States
First People's Hospital of Hangzhou

Recruiting

A RCT of the Efficacy of Vonoprazan 20mg QD in the Treatment of Helicobacter Pylori Infection (VATH-1)

Helicobacter Pylori Infection | Proton Pump Inhibitor | Vonoprazan

China
Yooyoung Pharmaceutical Co., Ltd.

Completed

Clinical Trial to Assess the PK/PD of YYD601 20mg After Oral Administration if Healthy Adult Subjects (Phase1)

GERD

Korea, Republic of
Takeda

Completed

Effect of Dexlansoprazole on Bone Homeostasis

Bone and Bones | Homeostasis

United States
Yuhan Corporation

Completed

The Exploration for Pharmacodynamics and Pharmacokinetics of YH4808 New Formulation in Healthy Subjects

Healthy

Korea, Republic of
Yooyoung Pharmaceutical Co., Ltd.

Completed

Clinical Trial to Assess the Efficacy and Safety of YYD601 in NERD Patients

Non-erosive Reflux Disease

Korea, Republic of
Galderma R&D

Completed

Long Term Safety and Efficacy Study of Calcitriol 3 mcg/g Ointment in Pediatric Subjects With Plaque Psoriasis

Psoriasis Vulgaris

United States, Canada, Belgium, Germany, Italy
AstraZeneca

Completed

Comparative Efficacy & Safety Study of D961H Versus Placebo for the Prevention of Gastric and Duodenal Ulcers With Low-dose Aspirin

Prevention

Korea, Republic of, Japan, Taiwan

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