Search clinical trials for: Optimized Background Therapy

Total 20383 results

Otsuka Pharmaceutical Development & Commercialization...

Terminated

Safety and Pharmacokinetics (PK) in Multidrug-Resistant (MDR) Refractive Tuberculosis

Tuberculosis

Latvia, Lithuania
United BioPharma

Not yet recruiting

UB-421 Combine With Optimized Background Therapy Regimen in Multi-Drug Resistant HIV-1 Infection Patients

HIV-1 Infection
National Institute of Allergy and Infectious Diseases...
Otsuka Pharmaceutical Development & Commercialization, Inc.

Recruiting

Evaluating the Pharmacokinetics, Safety, and Tolerability of Delamanid in Combination With Optimized Multidrug Background Regimen (OBR) for Multidrug-Resistant Tuberculosis (MDR-TB) in HIV-Infected and HIV-Uninfected Children With MDR-TB

HIV Infections | Tuberculosis

Tanzania, India, South Africa, Botswana
Otsuka Pharmaceutical Development & Commercialization...

Completed

A Trial to Evaluate OPC 67683 in Participants With Pulmonary Sputum Culture-positive, Multidrug-resistant Tuberculosis (TB)

Tuberculosis, Pulmonary | Extensively Drug-Resistant Tuberculosis | Tuberculosis, Multidrug Resistant

Korea, Republic of, China, United States, Egypt, Estonia, Japan, Latvia, Peru, Philippines
University Hospital, Bordeaux

Completed

Impact of a Therapeutic Education Program of Patient on the Evolution of the Cardiovascular Chronic Disease (ETHEPAT)

Myocardial Infarction | Stroke

France
Carlo Chiesa
Associazione Italiana per la Ricerca sul Cancro

Recruiting

Metastatic Thyroid Cancer Therapy Optimization With 124I PET Dosimetry (131THEROPT124)

Metastatic Differentiated Thyroid Cancer

Italy
TaiMed Biologics Inc.
Westat

Completed

Ibalizumab Plus Optimized Background Regimen in Treatment-Experienced Patients With Multi-Drug Resistant HIV-1

HIV

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Study of a Single Dose of Pretomanid Added to an Optimized Background Regimen in Children With Rifampicin-Resistant Tuberculosis

Tuberculosis | Rifampicin Resistant Tuberculosis

Brazil, India, South Africa, Tanzania, Thailand
Otsuka Pharmaceutical Development & Commercialization...

Completed

A 6-Month Safety, Efficacy, and Pharmacokinetic (PK) Trial of Delamanid in Pediatric Participants With Multidrug Resistant Tuberculosis (MDR-TB)

Multidrug Resistant Tuberculosis

Philippines, South Africa
CytoDyn, Inc.

Completed

Randomized, Double-Blind, Placebo-Controlled Trial, Followed by Single-Arm Treatment of PRO 140 (PRO140)

HIV

United States, Puerto Rico
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

LET Optimized IMPT in Treating Pediatric Patients With Ependymoma

Ependymoma | Anaplastic Ependymoma

United States
ViiV Healthcare
Pfizer

Completed

Prospective Observational Epidemiologic Study of Maraviroc's Safety (POEM)

Human Immunodeficiency Virus

United States, Canada, Spain, Belgium, France, United Kingdom, Italy, Brazil, Puerto Rico, Germany, Greece
NYU Langone Health

Active, not recruiting

Aerobic Exercise and Aphasia Treatment

Aphasia

United States
Hoffmann-La Roche

Completed

INNOVE Study: A Study of 3 Months Induction With Fuzeon (Enfuvirtide) + Optimized Background (OB) Versus OB Alone in HIV-1 Infected Patients With Virological Failure.

HIV Infections

France
Gilead Sciences

Active, not recruiting

Study to Evaluate the Safety and Efficacy of Lenacapavir (GS-6207) in Combination With an Optimized Background Regimen (OBR) in Heavily Treatment Experienced Participants Living With HIV-1 Infection With Multidrug Resistance (CAPELLA)

HIV-1-infection

United States, Spain, France, Taiwan, Japan, Thailand, Dominican Republic, Germany, Canada, Italy, South Africa
Impulse Dynamics

Completed

Evaluate Safety and Efficacy of the OPTIMIZER® System in Subjects With Moderate-to-Severe Heart Failure: FIX-HF-5C (FIX-HF-5C)

NYHA Class III Heart Failure | NYHA Class IV Heart Failure

United States, Germany, Czechia
National Institute of General Medical Sciences...

Completed

Virtual Reality Analgesia During Pediatric Physical Therapy (VRD/Peds)

Burn

United States
TaiMed Biologics Inc.

Completed

Ibalizumab Plus Optimized Background Regimen in Patient With Multi-Drug Resistant HIV

HIV

United States, Taiwan, Puerto Rico
ViiV Healthcare
Pfizer

Completed

Trial of Maraviroc (UK-427,857) in Combination With Optimized Background Therapy Versus Optimized Background Therapy Alone for the Treatment of HIV-1 Infected Subjects (MOTIVATE 2)

HIV Infections

Netherlands, United States, Italy, Spain, United Kingdom, France, Germany, Australia, Switzerland, Belgium, Canada, Poland, Sweden
Center Eugene Marquis

Completed

Internal Radiation Therapy for Hepatocellular Carcinomas With Therasphere: Optimized Dosimetry Versus Standard Dosimetry

Adenoma, Liver Cell

France
Centro Prevenzione Malattie Cardiovascolari N....

Unknown

Atrioventricular Junction Ablation and Biventricular Pacing for Atrial Fibrillation and Heart Failure (APAF-CRT)

Permanent Atrial Fibrillation

Italy
ViiV Healthcare
Pfizer

Completed

Trial of Maraviroc (UK-427,857) in Combination With Optimized Background Therapy Versus Optimized Background Therapy Alone for the Treatment of HIV-1 Infected Subjects (MOTIVATE 1)

HIV Infections

United States, Canada
ViiV Healthcare
Pfizer

Completed

Trial of Maraviroc (UK-427,857) in Combination With Optimized Background Therapy Versus Optimized Background Therapy Alone for the Treatment of Antiretroviral-Experienced NonCCR5-Tropic HIV-1 Infected Subjects

HIV Infections

Canada, United States, United Kingdom, Netherlands, Australia, Germany, Spain, Belgium, Switzerland
Myrexis Inc.

Terminated

A Study to Assess the Long-term Efficacy (24 Weeks) of MPC-4326 in Combination With a 2-3 Drug OBR Relative to the Efficacy of a 3-4 Drug ARV Regimen in Treatment Experienced HIV-1 Infected Subjects Who Are Failing Current Antiretroviral Therapy

HIV Infections

Canada, United States
Mayo Clinic

Completed

Environmental Factors to Increase Patient Comfort During Urodynamics Testing

Urologic Diseases | Lower Urinary Tract Symptoms

United States
Augustana College

Recruiting

A Feasibility Study of a Novel, Fully Remote Counseling and Sound Therapy Program for Hyperacusis

Hyperacusis

United States
University of California, Los Angeles
United States Agency for International Development (USAID); Ministry of Health... and other collaborators

Completed

Use of HIV Self-Test Kits to Increase Identification of HIV-Infected Individuals and Their Partners

HIV Infections

Malawi
Biotronik, Inc.

Completed

Interventricular Delay of Lumax HF-T for Heart Failure

Congestive Heart Failure

Switzerland, United States
University of Medicine and Pharmacy at Ho Chi Minh...

Completed

Comparing Efficacy of Optimal Treatment and Conventional Treatment for Major Depressive Disorder in Viet Nam

Major Depressive Disorder

Vietnam
Novartis Pharmaceuticals

Completed

Study in Primary Care Evaluating Inclisiran Delivery Implementation + Enhanced Support (SPIRIT)

Atherosclerotic Cardiovascular Disease | Atherosclerotic Cardiovascular Disease Risk Equivelents | Elevated Low Density Lipoprotein Cholesterol

United Kingdom
Tibotec Pharmaceuticals, Ireland

Completed

TMC125-TiDP35-C213: Safety and Antiviral Activity of Etravirine (TMC125) in Treatment-Experienced, HIV Infected Children and Adolescents

HIV-1

United States, France, Spain, Portugal, Canada, United Kingdom, South Africa, Argentina, Brazil, Puerto Rico, Thailand, Netherlands, Romania
Les Laboratoires des Médicaments Stériles

Completed

Optimized-dose Amoxicillin Versus Standard-dose Amoxicillin for Quadruple Therapy in Helicobacter Pylori Eradication (Helicomatri)

Helicobacter Pylori

Tunisia
Hoffmann-La Roche
Trimeris

Completed

A Study Comparing the Efficacy and Safety of Once-Daily Fuzeon (Enfuvirtide) Dosing Versus the Currently Recommended Twice-Daily Dosing in Human Immunodeficiency Virus-Type 1 (HIV-1) Infected Patients

HIV Infections

United States, Canada, Puerto Rico
Chang Gung Memorial Hospital
Kaohsiung Medical University

Recruiting

The Effects of Background Noise for Adult Patients' Sleep Quality in Intensive Care Unit.

Sleep

Taiwan
University Hospital, Caen

Recruiting

Haemodynamic and Respiratory Effects of a Low Positive End Expiratory Pressure Associated With a Fluid Challenge in Knee-chest Position (OPTIPEP)

Surgery

France
Centre Hospitalier Intercommunal de Toulon La Seyne...
Hamilton Medical AG

Recruiting

Patient-ventilator Synchronisation Study for Intensive Care Unit Patients (SyncAutoVNI)

Acute Respiratory Failure

France
Impulse Dynamics

Recruiting

Assessment of CCM in HF With Higher Ejection Fraction (AIM HIGHer)

Heart Failure | Heart Failure With Preserved Ejection Fraction | Diastolic Heart Failure | Heart Failure With Mid Range Ejection Fraction | Heart Failure With Moderately Reduced Ejection Fraction

United States
University of Copenhagen
Herlev and Gentofte Hospital

Completed

Developing and Testing Delicious and Nutritious for the Old People

Quality of Life | Nutritional Deficiency | Physical Performance

Denmark
University of North Carolina, Chapel Hill
Robert Wood Johnson Foundation

Completed

Designing Impactful Warnings for Sugary Drinks

Health Behavior

United States
Clinica Gema Leon

Recruiting

Impact of Craniosacral Treatment on Child Neurodevelopment

Child Development Disorder

Spain
Regeneron Pharmaceuticals

Completed

Study of Evinacumab (REGN1500) in Participants With Persistent Hypercholesterolemia

Hypercholesterolemia

United States, Spain, Australia, Netherlands, Japan, Jordan, Denmark, Israel, Sweden, South Africa, Canada, Austria, Czechia, France, Italy, New Zealand, Norway, Poland, Russian Federation, United Kingdom
Otsuka Pharmaceutical Development & Commercialization...

Completed

Pharmacokinetic and Safety Trial to Determine the Appropriate Dose for Pediatric Patients With Multidrug Resistant Tuberculosis

Pediatric | Multidrug Resistant Tuberculosis

Philippines, South Africa
Chongqing University Cancer Hospital

Recruiting

NBI Combined With MRI to Guide CTV Optimization in Eccentric Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma by AJCC V8 Stage

China
Beijing Aerospace General Hospital

Completed

A Clinical Study of Optimized CT-guided Pulmonary Nodule Microcoil Localization Technique

Pulmonary Nodule, Solitary

China
Hoffmann-La Roche

Completed

Efficacy, and Safety Study of Optimized Background Antiretroviral Regimen (OB) in Combination With Enfuvirtide in the Treatment-Experienced Participants With Human Immunodeficiency Virus-1 (HIV-1) Infection

HIV Infections

France
University of Texas at Austin

Unknown

Do Patients Perceive Surgeons Who Provide Personal Information as More Trustworthy and Empathetic?

Trust
University Hospital, Montpellier

Completed

Impact of an Optimized Communication on the Readmission for Adverse Drug Event (URGEIM)

Adverse Drug Event

France
Duke University

Completed

Quality Improvement - Monitoring Alarm Optimization Study (QI-MAOS)

No Applicable Condition; Study of Physiologic Monitor Alarms
Beijing Children's Hospital

Unknown

Management Following Lumbar Puncture In Children (MFLPIC)

Spinal Puncture Complications
University Hospital, Geneva

Terminated

Impact of Early Goal-directed Fluid Therapy in Hypovolemic Patients Undergoing Emergency Surgery

Trauma | Surgery | Emergency | Hypovolemic Shock

Switzerland

Search clinical trials for: Optimized Background Therapy

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