Search clinical trials for: Oxazolidinones

Total 41 results

AstraZeneca
Quintiles, Inc.

Completed

Study to Evaluate Safety, Tolerability and Pharmacokinetics (PK) (Including Food Effect) of Oral Doses of AZD5847 in Healthy Volunteers

Healthy

United States
University of Southern California
Merck Sharp & Dohme LLC

Completed

Pharmacokinetics of Tedizolid Phosphate in Cystic Fibrosis

Cystic Fibrosis

United States
Melinta Therapeutics, Inc.

Completed

Safety and Efficacy Study of Oxazolidinone to Treat Pneumonia

Community-Acquired Pneumonia (CAP)

Canada, United States, Russian Federation
Lundquist Institute for Biomedical Innovation at...

Completed

Tolerability, Safety, and Efficacy of Tedizolid as Oral Treatment for Bone and Joint Infections (OTTER)

Bone and Joint Infection

United States
Sequella, Inc.

Completed

PNU-100480 In Newly Diagnosed, Drug Sensitive Patients With Pulmonary TB; Early Bactericidal Activity; Whole Blood Assay

Tuberculosis

South Africa
Sequella, Inc.

Completed

Safety, Tolerability, Pharmacokinetics And Measurement Of Whole Blood Activity (WBA) Of PNU-100480 After Multiple Oral Doses In Healthy Adult Volunteers

Tuberculosis

United States
Melinta Therapeutics, Inc.

Completed

Safety and Efficacy Study of Oxazolidinones to Treat Uncomplicated Skin Infections

Streptococcal Infections | Abscess | Staphylococcal Skin Infections | Infectious Skin Diseases | Bacterial Skin Diseases

United States
Merck Sharp & Dohme LLC

Completed

A Study of the Safety and Efficacy of Anacetrapib (MK-0859) When Added to Ongoing Statin Therapy in Japanese Participants With Dyslipidemia (MK-0859-051 AM1)

Dyslipidemia
Merck Sharp & Dohme LLC

Completed

A Study of the Safety and Efficacy of Anacetrapib (MK-0859) When Added to Ongoing Statin Therapy in Japanese Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-050)

Heterozygous Familial Hypercholesterolemia (HeFH)
LegoChem Biosciences, Inc

Terminated

An Open-label, Single Dose, Parallel Design, Phase 1 Clinical Study of LCB01-0371

Healthy

Korea, Republic of
University of Oxford
Merck Sharp & Dohme LLC

Active, not recruiting

REVEAL: Randomized EValuation of the Effects of Anacetrapib Through Lipid-modification (REVEAL)

Atherosclerotic Cardiovascular Disease

United Kingdom
Sequella, Inc.

Completed

Safety, Tolerability And Pharmacokinetics Study Of Single Doses Of PNU-100480 In Healthy Adults

Tuberculosis

United States
Trius Therapeutics LLC

Completed

A Pharmacokinetics and Safety Study in Subjects With Renal Impairment

Renal Impairment

United States
LegoChem Biosciences, Inc

Completed

IV Dosage Form of LCB01-0371 Phase I Study in Healthy Male Volunteers

Healthy

Korea, Republic of
Bayer
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety of Intravenous to Oral 6-Day Tedizolid Phosphate vs. Intravenous to Oral 10-Day Linezolid in Patients With Acute Bacterial Skin and Skin Structure Infection (ABSSSI)

Bacterial Infections

China, United States, Philippines, Taiwan
Merck Sharp & Dohme LLC

Completed

A Pharmacokinetic Study of Tedizolid Phosphate in Pediatric Participants With Gram-Positive Infections (MK-1986-014)

Gram-Positive Infections

United States, Bulgaria, Colombia, Norway, United Kingdom
Actelion

Completed

Efficacy and Safety of Cadazolid Versus Vancomycin in Subjects With Clostridium Difficile - Associated Diarrhea

Clostridium Difficile Infection

United States, Australia, Brazil, Canada, France, Germany, Italy, Netherlands, Peru, Poland, Romania, Spain
LegoChem Biosciences, Inc

Completed

Multiple Ascending Dose, Phase 1 Clinical Study of LCB01-0371

Healthy

Korea, Republic of
Merck Sharp & Dohme LLC

Completed

A Study of Oral and Intravenous (IV) Tedizolid Phosphate in Hospitalized Participants, Ages 2 to <12 Years, With Confirmed or Suspected Bacterial Infection (MK-1986-013)

Gram-Positive Bacterial Infections
LegoChem Biosciences, Inc

Completed

Multiple Ascending Dose Study for LCB01-0371

Healthy

Korea, Republic of
Actelion

Completed

Efficacy and Safety of Cadazolid Versus Vancomycin in Subjects With Clostridium Difficile-associated Diarrhea

Clostridium Difficile Infection

United States, Belgium, Israel, Argentina, Brazil, Canada, Chile, Croatia, Czechia, Greece, Hungary, Korea, Republic of, Romania, Slovakia
LegoChem Biosciences, Inc

Recruiting

A Phase 2a Study, Effect of Vancomycin With vs Without Delpazolid (LCB01-0371) in Patients With MRSA Bacteremia

MRSA Bacteremia

Korea, Republic of
Actelion

Completed

Efficacy, Safety and Tolerability of Cadazolid in Subjects With Clostridium Difficile Associated Diarrhea (CDAD)

Clostridium Difficile Infection

United States, Canada, Germany, Italy, Sweden, United Kingdom
LegoChem Biosciences, Inc

Completed

Trial to Evaluate Bioequivalence of LCB01-0371 in Different Batches

Healthy

Korea, Republic of
Parc de Salut Mar
Food and Drug Administration (FDA)

Completed

Pharmacokinetics in Oral and Intranasal Formulations of Zolmitriptan.

Healthy

Spain
Primus Pharmaceuticals
Illumination Health

Recruiting

Efficacy of M640 in Acute Lumbosacral Musculoskeletal Conditions.

Lumbar Spinal Stenosis | Sciatica Acute

United States
LegoChem Biosciences, Inc

Completed

To Evaluate the Effect of Food on Pharmacokinetics(PK), Phase I Clinical Study of LCB01-0371

Healthy

Korea, Republic of
Zosano Pharma Corporation

Completed

A Study to Evaluate the Long-Term Safety of M207 in the Acute Treatment of Migraine (ADAM)

Migraine

United States
AstraZeneca

Completed

Zomig - Treatment of Acute Migraine Headache in Adolescents (TEENZ)

Migraine Headache

United States, Estonia, Hungary, Latvia, Poland, Finland, Slovakia, Serbia
Primus Pharmaceuticals
ClinOhio Research Services, LLC

Recruiting

Study to Assess Drowsiness, Cognition, Fall Risk After Metaxalone 640 mg and Metaxalone 800 mg

Healthy Participants

United States
Xijing Hospital

Unknown

Efficacy and Safety of Zolmitriptan by Sublingual Administration

Cluster Headache
Acorda Therapeutics

Completed

Safety and Pharmacokinetics (PK) Study of Single Ascending Doses of CVT-427 (Zolmitriptan Inhalation Powder) In Healthy Adults

Migraine

United States
Merck Sharp & Dohme LLC

Completed

A Study of the Safety and Efficacy of Anacetrapib (MK-0859) When Added to Ongoing Statin Therapy (MK-0859-021)

Hypercholesterolemia
Trius Therapeutics LLC

Completed

Ascending Dose Pharmacokinetic (PK) and Absolute Bioavailability (BA) (IV/SAD/MAD)

Bacterial Infections

United States
LegoChem Biosciences, Inc

Completed

A Phase II Clinical Study of LCB01-0371 to Evaluate the EBA, Safety and PK

Pulmonary Tuberculosis

Korea, Republic of
Trius Therapeutics LLC

Completed

A Thorough QT Study of TR-701free Acid (FA) in Healthy Subjects

Healthy Volunteer

United States
Merck Sharp & Dohme LLC

Completed

Study of Telcagepant (MK-0974) in Participants With Moderate to Severe Acute Migraine With or Without Aura (MK-0974-011)

Migraine
National Institute of Allergy and Infectious Diseases...
TB Alliance

Not yet recruiting

Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis (RAD-TB)

Pulmonary Tuberculosis

Botswana, Brazil, Haiti, India, Kenya, Malawi, Mexico, Peru, Philippines, South Africa, Thailand, Uganda, Zimbabwe
Zosano Pharma Corporation

Completed

A Study of M207 With Intranasal Zolmitriptan in Healthy Volunteers

Migraine

United States
Bill & Melinda Gates Medical Research Institute
Global Alliance for TB Drug Development; Janssen Pharmaceutica; Otsuka Pharmaceutical...

Recruiting

Efficacy and Safety Evaluation of Two to Four Months of Treatment With the Combination Regimens of DBOS and PBOS in Adults With Pulmonary Tuberculosis

Pulmonary Tuberculosis

Philippines, South Africa
Fundacion Clinic per a la Recerca Biomédica

Not yet recruiting

Oral Antimicrobial Treatment vs. Outpatient Parenteral for Infective Endocarditis (OraPAT-IEGAMES)

Endocarditis Infective

Spain

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